Code
179I0207
Duration
01 December 2007 → 30 November 2011
Funding
Regional and community funding: various
Promotor
Research disciplines
-
Natural sciences
- Microbiology
- Systems biology
-
Medical and health sciences
- Immunology
- Laboratory medicine
- Microbiology
- Immunology
- Laboratory medicine
- Microbiology
- Immunology
- Laboratory medicine
- Microbiology
Keywords
protein-protein interactions
nef
LEDGF/p75
Project description
Our objective is to increase basic understanding of protein-protein interactions, to develop technology to identify and validate protein-protein interaction relevent for human disease and to develop assays and evaluate inhibitors of protein-protein interaction. Specifically, we want to develop novel treatment strategies for HIV infection by targeting cellular co-factors involved in HIV replication: Lens Epithelium Derived Growth Factor (LEDGF/p75) and Nef.