Sorting out functionally conserved plant orthologs using comparative expression analysis

01 January 2015 → 31 December 2020
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Scientific computing
    • Bioinformatics and computational biology
    • Plant biology
  • Medical and health sciences
    • Bioinformatics and computational biology
    • Bioinformatics and computational biology
    • Public health care
    • Public health services
    • Bioinformatics and computational biology
  • Engineering and technology
    • Biomaterials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
    • Scientific computing
alternative splicing gene ontology comparative transcriptomics orthology RNA-Seq function prediction
Project description

New methods will be developed to predict functions for genes and transcripts. These methods will robustly transfer functions between coexpressing transcripts and will detect orthologs with a conserved coexpression context. This allows to make high quality function predictions, even for species with few known exerimental functions or with a large evolutionary distance to a model organism.