Code
01J07408
Duration
01 January 2008 → 31 December 2012
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
-
Engineering and technology
- Chemical product design and formulation
- Biomaterials engineering
Keywords
biodegradable
siRNA
nanogel
controlled release
Project description
For in vivo application of therapeutic siRNA, effective delivery is still defined as the major hurdle to overcome. Also, appropriate attention should be paid to optimize the gene silencing effect, both in terms of magnitude and duration. The major focus of this project is therefore the design of dextran nanogels for intracellular controlled release of siRNA.