Benchtop photoporator

15 July 2017 → 14 July 2019
Regional and community funding: Industrial Research Fund
Research disciplines
  • Natural sciences
    • Other biological sciences
nanotechnology photoporation Cell transfections vapor nanobubbles biophotonics
Project description

Introduction of exogenous material into the cytoplasm of living cells is an important aspect of different biomedical applications. Throughout the cell membrane, inducing toxicity without cell is the most important bottleneck. Meanwhile, various techniques have been developed where electroporation and lipofection are the best known for in vitro and ex vivo applications. Nevertheless, these technologies have important limitations in terms of versatility, toxicity and efficiency.

In recent years, the promoter and his team pioneered nanoparticle (NP) facilitated photoporation, which can solve many of the shortcomings of current commercially available methods. The team proved in various research areas the added value and versatility of this technology to bring in material and this with very limited toxicity. The growing interest of potential customers is evident in the increasing number of requests from various life-science groups to use the technology as a research method.

A unique opportunity arises to put a photo-imaging device and related disposables on the market. Our first goal is to translate the complex lab setup into an integrated, user-friendly table model, including software. The feedback from our users will show the need for further optimization before we can put an efficient device on the market and the generated PoCs will help convince future customers of the value of this technology. At the end of the project, our goal is to draw up a business plan with a clear understanding of the pricing of the products and the investments needed to start the spin-off.