Research Explorer

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Project

Understanding the immunological basis of persistent airway obstruction in asthma

Outputs and Outcomes

Publications

Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Martijn SchuijsClaudia Mariela Brenis GómezFabian BickJustine Van MoorleghemManon VanheerswynghelsGeert van LooRudi BeyaertDavid VoehringerRichard M. LocksleyHamida HammadBart Lambrecht et al.

U Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma

Fabian BickClaudia Mariela Brenis GómezInés LammensJustine Van MoorleghemCaroline De WolfSam DupontLaure DumoutierNeal P. SmithAlexandra-Chloé VillaniRobin BrowaeysJehan AlladinaAlexis M. HaringBenjamin D. MedoffJosalyn L. ChoRené BigirimanaJoao VieiraHamida HammadChristophe BlanchetotMartijn SchuijsBart Lambrecht et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

Nincy DebeufSahine LameireManon VanheerswynghelsJulie DeckersCaroline De WolfWendy ToussaintRein VerbekeKevin VerstaenHamida HammadStijn VanheeBart Lambrecht et al.

Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells

Katrien Van Der BorghtJens BrimnesEline HaspeslaghStephanie BrandKatrijn NeytShashank GuptaNiels Peter Hell KnudsenHamida HammadPeter S. AndersenBart Lambrecht

A1 Journal Article in MUCOSAL IMMUNOLOGY

Ym1 protein crystals promote type 2 immunity

Ines HeyndrickxKim DeswarteKenneth VerstraeteKoen VerschuerenUrsula SmoleHelena Catharine AegerterAnn DansercoerHamida HammadSavvas SavvidesBart Lambrecht

A1 Journal Article in ELIFE

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy WullaertTino HochepiedEsther HosteLieselotte Vande WalleMohamed LamkanfiSavvas SavvidesDirk ElewautBart LambrechtGeert van Loo et al.

A1 Journal Article in SCIENTIFIC REPORTS

CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes

Kavita RawatAnita TewariXin LiArlind B. B. MaraWilliam T. T. KingSophie L. L. GibbingsChinaza F. F. NnamFred W. W. KollingBart LambrechtClaudia V. V. Jakubzick

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn VerwaerdeNicky VermeulenSahine LameireNincy DebeufJulie DeckersPatrick StordeurPieter DepuydtEva Van BraeckelLinos VandekerckhoveMartin GuilliamsSjoerd SchettersFilomeen HaerynckSimon TavernierBart Lambrecht et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity

Bastiaan MaesFarzaneh FayazpourLeen CatrysseGuillaume LornetEvelien Van De VeldeCaroline De WolfSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsKim DeswarteBenedicte DescampsChristian VanhoveBart Van der SchuerenRoman VangoitsenhovenHamida HammadSophie JanssensBart Lambrecht et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

RNA viruses alter house dust mite physiology and allergen production with no detected consequences for allergenicity

José Cristian Vidal‐QuistJozefien DeclercqStijn VanheeBart LambrechtJosé Gómez‐RialCarmen VidalEylem Aydogdu LohausStephane RombautsPedro Hernández‐Crespo

A1 Journal Article in INSECT MOLECULAR BIOLOGY

Biology of lung macrophages in health and disease

Helena Catharine AegerterBart LambrechtClaudia V. Jakubzick

A1 Journal Article in IMMUNITY

Advancing lung immunology research : an official American Thoracic Society workshop report

Rod A. RahimiJosalyn L. ChoV Jakubzick, ClaudiaShabaana A. KhaderBart LambrechtClare M. LloydAri B. MolofskySebastien TalbotCatherine A. BonhamWonder P. DrakeI Sperling, AnneBenjamin D. Singer et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection : from prognostic marker to therapeutic agent

Jozefien DeclercqElisabeth De LeeuwBart Lambrecht

A1 Journal Article in CYTOKINE

The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice

Bastiaan MaesUrsula SmoleMatthias VanderkerkenKim DeswarteJustine Van MoorleghemKarl VergoteManon VanheerswynghelsCaroline De WolfSofie De PrijckNincy DebeufBenjamin PavieWendy ToussaintSophie JanssensSavvas SavvidesBart LambrechtHamida Hammad et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY