Research Explorer

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Project

Understanding the immunological basis of persistent airway obstruction in asthma

Outputs & Impact

Publications & research data ( 23 )

Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus

Jose Cristian Vidal-QuistFelix OrtegoBart LambrechtStephane RombautsPedro Hernandez-Crespo

A1 Journal Article in BMC GENOMICS

Targeting γc family cytokines with biologics : current status and future prospects

Fabian BickChristophe BlanchetotBart LambrechtMartijn Schuijs

A1 Journal Article in MABS

A genetically encoded endogenous antibody recruitment strategy for innate immune-mediated killing of cancer cells

Justine AelvoetZifu ZhongClaudia Mariela Brenis GómezHelena Catharine AegerterBenoit LouageBart LambrechtBruno De GeestMartijn Schuijs

A1 Journal Article in ADVANCED MATERIALS

Small-angle X-ray scattering of engineered antigen-binding fragments : the case of glycosylated Fab from the Mannitou IgM antibody

Shubham SemwalMaria KaramolegkouStéphanie FlamentNessim RaouraouaKenneth VerstraeteAurélien ThureauFrank WienFabrice BraySavvas SavvidesJulie Bouckaert

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS

A reappraisal of IL-9 in inflammation and cancer

Fabian BickChristophe BlanchetotBart LambrechtMartijn Schuijs

A1 Journal Article in MUCOSAL IMMUNOLOGY

Coordinated chemokine expression defines macrophage subsets across tissues

Xin LiArlind B. MaraShawn C. MusialFred W. KollingSophie L. GibbingsNikita GerebtsovClaudia V. Jakubzick

A1 Journal Article in NATURE IMMUNOLOGY

TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders

Nincy DebeufSahine LameireManon VanheerswynghelsJulie DeckersCaroline De WolfWendy ToussaintRein VerbekeKevin VerstaenHamida HammadStijn Vanhee et al.

A2 Journal Article in ELIFE

Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa

Jozefien DeclercqSarah GerloSharon Van NevelNatalie De RuyckGabriële HoltappelsLiesbeth DelesieEls TobbackInés LammensNikita GerebtsovKoen Sedeyn et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Inhaled GM-CSF administered during ongoing pneumovirus infection alters myeloid and CD8 T cell immunity without affecting disease outcome

Nincy DebeufJulie DeckersSahine LameireCedric BosteelsHamida HammadBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Case report : dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma : a proteome analysis

Manon BlauwblommePhilippe GevaertSharon Van NevelSebastian RiemannElke VandewalleGabriële HoltappelsNatalie De RuyckLara DeryckeAnne-Sophie EeckelsStijn Vanhee et al.

A2 Journal Article in FRONTIERS IN ALLERGY

Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Martijn SchuijsClaudia Mariela Brenis GómezFabian BickJustine Van MoorleghemManon VanheerswynghelsGeert van LooRudi BeyaertDavid VoehringerRichard M. LocksleyHamida Hammad et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma

Fabian BickClaudia Mariela Brenis GómezInés LammensJustine Van MoorleghemCaroline De WolfSam DupontLaure DumoutierNeal P. SmithAlexandra-Chloé VillaniRobin Browaeys et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells

Katrien Van Der BorghtJens BrimnesEline HaspeslaghStephanie BrandKatrijn NeytShashank GuptaNiels Peter Hell KnudsenHamida HammadPeter S. AndersenBart Lambrecht

A1 Journal Article in MUCOSAL IMMUNOLOGY

Ym1 protein crystals promote type 2 immunity

Ines HeyndrickxKim DeswarteKenneth VerstraeteKoen VerschuerenUrsula SmoleHelena Catharine AegerterAnn DansercoerHamida HammadSavvas SavvidesBart Lambrecht

A1 Journal Article in ELIFE

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy Wullaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes

Kavita RawatAnita TewariXin LiArlind B. B. MaraWilliam T. T. KingSophie L. L. GibbingsChinaza F. F. NnamFred W. W. KollingBart LambrechtClaudia V. V. Jakubzick

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity

Bastiaan MaesFarzaneh FayazpourLeen CatrysseGuillaume LornetEvelien Van De VeldeCaroline De WolfSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsKim Deswarte et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

RNA viruses alter house dust mite physiology and allergen production with no detected consequences for allergenicity

José Cristian Vidal‐QuistJozefien DeclercqStijn VanheeBart LambrechtJosé Gómez‐RialCarmen VidalEylem Aydogdu LohausStephane RombautsPedro Hernández‐Crespo

A1 Journal Article in INSECT MOLECULAR BIOLOGY

Biology of lung macrophages in health and disease

Helena Catharine AegerterBart LambrechtClaudia V. Jakubzick

A1 Journal Article in IMMUNITY

Advancing lung immunology research : an official American Thoracic Society workshop report

Rod A. RahimiJosalyn L. ChoV Jakubzick, ClaudiaShabaana A. KhaderBart LambrechtClare M. LloydAri B. MolofskySebastien TalbotCatherine A. BonhamWonder P. Drake et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection : from prognostic marker to therapeutic agent

Jozefien DeclercqElisabeth De LeeuwBart Lambrecht

A1 Journal Article in CYTOKINE

The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice

Bastiaan MaesUrsula SmoleMatthias VanderkerkenKim DeswarteJustine Van MoorleghemKarl VergoteManon VanheerswynghelsCaroline De WolfSofie De PrijckNincy Debeuf et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )