Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

STOP SEPSIS

Outputs & Impact

Publications & research data ( 19 )

CARD14 signaling in intestinal epithelial cells induces intestinal inflammation and intestinal transit delay

Aigerim AidarovaMarieke CarelsMira HaegmanYasmine DriegeSteven TimmermansEline Van DammeJavier Aguilera-LizarragaMaria Francesca ViolaRita de Cassia de Oliveira CollacoJoan Manils et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

Louise NuyttensMarah HeyerickMaxime RoesElise MoensCéline Van DenderCharlotte WallaeysTino HochepiedSteven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Céline Van DenderSteven TimmermansMaxime RoesMadeleine HellemansElise MoensLouise NuyttensMaarten ClaesBart RomanKarolien De BosscherJolien Vandewalle et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

Louise NuyttensMarah HeyerickGeike HeremansElise MoensMaxime RoesCéline Van DenderLiesbet De BusJohan DecruyenaereJan De WaeleJolien Vandewalle et al.

A1 Journal Article in CELL REPORTS

Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Natalia Garcia GonzalezCharlotte WallaeysWendy ToussaintTino HochepiedSylviane DewaeleSomara De BeulRobin Van LokeJolien VandewalleSteven TimmermansClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Modulation of glucocorticoid receptor function under iron overload

Wanting ZhuTineke VanderhaeghenSteven TimmermansJolien VandewalleMelanie EggermontNicolette J. D. VerhoogClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Balancing metabolism and regeneration in liver diseases through HNF4α targeting

Céline Van DenderJolien VandewalleClaude Libert

A1 Journal Article in TRENDS IN ENDOCRINOLOGY AND METABOLISM

Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

Steven TimmermansCharlotte WallaeysSomara De BeulNatalia Garcia GonzalezClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

Fëllanza HalimiTineke VanderhaeghenSteven TimmermansSiska CroubelsClaude LibertJolien Vandewalle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sepsis-induced changes in pyruvate metabolism : insights and potential therapeutic approaches

Louise NuyttensJolien VandewalleClaude Libert

A1 Journal Article in EMBO MOLECULAR MEDICINE

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van DenderSteven TimmermansVille PaakinahoTineke VanderhaeghenJolien VandewalleMaarten ClaesBruno GarciaBart RomanJan De WaeleSiska Croubels et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Identification and characterization of multiple Paneth cell types in the mouse small intestine

Steven TimmermansCharlotte WallaeysNatalia Garcia GonzalezLotte PollarisYvan SaeysClaude Libert

A1 Journal Article in CELLS

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte WallaeysNatalia Garcia GonzalezSteven TimmermansJolien VandewalleTineke VanderhaeghenSomara De BeulHester DufoorMelanie EggermontElise MoensVictor Bosteels et al.

A1 Journal Article in CELL HOST & MICROBE

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Sofie DesmetJonathan ThommisTineke VanderhaeghenEdmee VandenboornDorien ClarisseYunkun LiSteven TimmermansDaria FijalkowskaDariusz RatmanEvelien Van Hamme et al.

A1 Journal Article in MOLECULAR METABOLISM

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke VanderhaeghenSteven TimmermansMelanie EggermontDeepika WattsJolien VandewalleCharlotte WallaeysLouise NuyttensJoyca De TemmermanTino HochepiedSylviane Dewaele et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Mousepost 2.0, a major expansion of the resource

Steven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock

Jolien VandewalleBruno GarciaSteven TimmermansTineke VanderhaeghenLise Van WyngeneMelanie EggermontHester DufoorCéline Van DenderFëllanza HalimiSiska Croubels et al.

A1 Journal Article in CELLS

Sepsis : a failing starvation response

Jolien VandewalleClaude Libert

A1 Journal Article in TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dimerization of the glucocorticoid receptor and its importance in (patho)physiology : a primer

Steven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in CELLS

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )