Importance and interaction of allergy, infections and respiratory environmental exposures in chronic lower & upper airway diseases

01 January 2007 → 31 March 2012
Federal funding: various
Research disciplines
  • Medical and health sciences
    • Respiratory medicine
    • Respiratory medicine
    • Respiratory medicine
airway diseases
Project description

The acronym AIReWAY describes the global objective of this project. With this interuniversity approach, we want to unravel cellular and molecular mechanisms underlying the upper (rhinitis, sinusitis, nasal polyposis) and lower airway diseases (asthma and COPD). The individual and combined effects of allergens. infections and air pollution on the main cellular and molecular mediators, will be characterized at different phases typing the natural history of each disease entity, using experimental animal models. In addition, validation will be realized by analyses on material from healthy controls and defined study populations.