Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Does angiopoietin-Tie signaling affect podocyte integrity in kidney glomeruli?

Outputs and Outcomes

Code

01J01919

Duration

01 October 2019 → 30 July 2024

Funding

Regional and community funding: Special Research Fund

Promotor

Ward De Spiegelaere

Research disciplines

Agricultural and food sciences
- Veterinary anatomy, morphology and (clinical) pathology

Keywords

podocytes kidney glomeruli angiopoietins TIE2-receptor

Project description

We recently discovered TIE1 and TIE2 receptor signaling on kidney glomerular podocytes, which are important cells of the glomerular filtration barrier. To investigate if TIE-receptors regulate glomerular integrity, we will investigate the role of this signaling system on podocyte function, i.e. survival, migration, proliferation and permeability. In addition, we will investigate the downstream
signaling pathways regulated by TIE-receptors in podocytes.

English

Dutch

English

Cookie settings

In addition to functional cookies which are necessary for the website to function, Ghent University uses non-functional cookies such as statistical cookies and social media cookies. These non-functional cookies can also be placed by third parties, for example to measure the use of the site or to share content on social media. Certain media are only available if you accept the cookies. You can set and modify your cookie preferences yourself. Find out what cookies we use and why in the Cookie Statement.

Analytics

AnalyticsWe'll collect information about your visit to our site. It helps us understand how the site is used – what's working, what might be broken and what we should improve.

Powered by