Research Explorer

Project

Effect of bioactive peptides on the cholecystokinin (CCK)-receptor regulating satiety and food intake in humans and insects
Code
01J13309
Duration
01 January 2009 → 31 October 2013
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Other chemical sciences
    • Biochemistry and metabolism
    • Plant biology
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Nutrition and dietetics
    • Medical biochemistry and metabolism
  • Agricultural and food sciences
    • Agricultural animal production
    • Agricultural plant production
    • Food sciences and (bio)technology
    • Horticultural production
Keywords
bioactive peptides cholecystokinin satiety in vitro insects rat in vivo
 
Project description
 

This project evaluates the potential of bioactive peptides to reduce food intake by interacting with the cholecystokinin (CCK)-receptor. After enzymatich hydrolysis of food proteins, bioactive peptides are isolated and their in vitro activity on the CCK-receptor is determined using a cell bioassay. Moreover, their in vivo satiating effect in rats and their potential in the control of insect pests are evaluated.