Project

Study on the influence of mycotoxin binders on the oral bioavailability, pharmacokinetics and tissue residues of veterinary drugs applied in poultry and pigs

Code

HGA160E91012

Duration

01 July 2012 → 30 June 2015

Funding

Regional and community funding: various

Promotor

Siska Croubels

Research disciplines

Natural sciences
- Analytical chemistry
- Other chemical sciences
- Animal biology
Medical and health sciences
- Nutrition and dietetics
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutical analysis and quality assurance
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
Agricultural and food sciences
- Agricultural animal production
- Food sciences and (bio)technology
- Veterinary medicine
- Other veterinary sciences
- Other agricultural and food sciences

Keywords

poultry pigs oral bioavailability pharmacokinetics food safety mycotoxin binders tissue residues drug interactions

Project description

Recent EFSA guidelines (2010) state that in vivo efficacy and safety of the currently available mycotoxin binders need to be studied. This project aims to identify and test the most common mycotoxin binders for possible interactions with orally administered veterinary drugs. Therefore, appropriate in vitro and in vivo tests will be executed.