Code
3E020614
Duration
01 October 2014 → 31 May 2020
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Genetics
- Systems biology
-
Medical and health sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
Keywords
developmental disorders
Project description
Studies of individuals with a genetic disease lacking coding mutations but with a non-coding genetic defect provided many insights into the function of cis-regulatory elements. An example of this is FOXL2, encoding a forkhead transcription factor playing a role in ovarian development. Here we aim to dissect the cis-regulatory landscape of FOXL2 and to identify and validate ovary-specific enhancers