Project

RealThe aging proteome and peptidome of the nematode model Caenorhabditis elegans.

Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • General biology
  • Medical and health sciences
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
    • Nursing
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
aging Peptidomics caenorhabditis elegans proteomics
 
Project description

By means of mass spectrometry, we will study the proteomic and peptidomic patterns in aging Caenorhabditis elegans nematodes. These patterns will also be focused on in worm populations showing lifespan extension (by mutation in the Ins/IGF signal transduction pathway, the mitochondria and by dietary restriction). We will search for functional overlap in the resulting patterns.