The versatility of biomass (food, fiber, materials, energy), the functional role of biomass in ecological processes and the fact that climate change is linked to issues of food, materials and energy security, degradation of ecosystems and loss of biodiversity require new (smart) forms of land management which can be tested and optimized through practical experiments. In its recent study 'A roadmap form moving to a competitive low carbon economy in 2050' the European Commission underlines the importance of more holistic views regarding land use, land use change and forestry. Bringing smart land use practice also plays a fundamental role in the sustainability of biomass for energy and material applications. The overall objective of this research is to develop a generic framework applicable on the basis of the Forest case study for simultaneous optimization of biomass production and other ecosystem services by means smart land management.