Research Explorer

Project

Elucidating the details of the interaction between specific nutrients-microbiota-intestinal health and the consequences for inflammatory diseases
Code
01G00419
Duration
01 January 2019 → 31 December 2023
Funding
Regional and community funding: Special Research Fund
Promotor-spokesperson
Research disciplines
  • Medical and health sciences
    • Gastro-enterology
    • Autoimmunity
    • Inflammation
    • Innate immunity
    • Regulation of metabolism
  • Agricultural and food sciences
    • Veterinary immunology
Keywords
microbiome signal transduction nuclear receptors health Inflammation inflammatory bowel disease sepsis infection nutrients
 
Project description
 

We will investigate the molecular mechanisms by which a number of nutrients (zinc, abscisic acid and berberine) protect against inflammatory and infectious diseases. We will focus on the effect of these nutrients on intestinal health and homeostasis. More specifically, we wish to study their effect on the composition of the gut microbiome and the interaction between gut microbes and gut epithelial cells.