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Infrastructure

Waters NanoAcquity / Synapt G2-Si LC-MS
Type
Equipment
Acronym
Synapt
Code
APP/00095
Date of commissioning
05 September 2016 → …
Research disciplines
  • Natural sciences
    • Analytical biochemistry
    • Proteins
    • Proteomics
  • Medical and health sciences
    • Protein diagnostics
    • Medical proteomics
    • Medical proteomics
  • Engineering and technology
    • Industrial molecular engineering of nucleic acids and proteins
Keywords
mass spectrometry proteomics HPLC proteins biomolecule analysis
Brand Name/manufacturer
SCIEX
Other information
 
Description
 

The Synapt G2-Si is a versatile Q-TOF device comprising Ion Mobility separation (IMS) and Electron Transfer Dissociation (ETD) capabilities. It allows for a plethora of different acquisition strategies, the most prominent of which are HDMSE or ion mobility-assisted data-independent acquisition and HDDDA or ion mobility-assisted data-dependent acquisition. Herein, both identification and quantitation is done on DIA data. The Synapt G2-Si is coupled to a Nano Acquity LC-system, capable of both capillary- and nano-flow LC.