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Researcher
Yvan Saeys
Profile
Projects
Publications
Activities
Awards & Distinctions
319
Results
2024
A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
Joanna Pozniak
Dennis Pedri
Ewout Landeloos
Yannick Van Herck
Asier Antoranz
Lukas Vanwynsberghe
Ada Nowosad
Niccolo Roda
Samira Makhzami
Greet Bervoets
et al.
A1
Journal Article
in
CELL
2024
An innate immune signature induced by AS01-or AS03-adjuvanted vaccines predicts the antibody response magnitude and quality consistently over time
Setareh Tasdighian
Viviane Bechtold
Ahmed Essaghir
Yvan Saeys
Wivine Burny
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2024
An introduction to adversarially robust deep learning
Jonathan Peck
Bart Goossens
Yvan Saeys
A1
Journal Article
in
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
2024
Defining and benchmarking open problems in single-cell analysis
Malte Luecken
Scott Gigante
Daniel Burkhardt
Robrecht Cannoodt
Daniel Strobl
Nikolay Markov
Luke Zappia
Giovanni Palla
Wesley Lewis
Daniel Dimitrov
et al.
Preprint
2024
Efficient cytometry analysis with FlowSOM in Python boosts interoperability with other single-cell tools
Artuur Couckuyt
Benjamin Rombaut
Yvan Saeys
Sofie Van Gassen
A1
Journal Article
in
BIOINFORMATICS
2024
Evaluating feature attribution methods in the image domain
Arne Gevaert
Axel-Jan Rousseau
Thijs Becker
Dirk Valkenborg
Tijl De Bie
Yvan Saeys
A1
Journal Article
in
MACHINE LEARNING
2024
Identification and characterization of multiple Paneth cell types in the mouse small intestine
Steven Timmermans
Charlotte Wallaeys
Natalia Garcia Gonzalez
Lotte Pollaris
Yvan Saeys
Claude Libert
A1
Journal Article
in
CELLS
2024
Incorporating Topological Priors Into Low-Dimensional Visualizations Through Topological Regularization
Edith Heiter
Robin Vandaele
Tijl De Bie
Yvan Saeys
Jefrey Lijffijt
U
Journal Article
in
IEEE Access
2024
Methods for differential expression analysis in single-cell transcriptomics at the gene- and subgene level
Jeroen Gilis
Lieven Clement
Yvan Saeys
Koen Van den Berge
Dissertation
2024
Myelodysplastic neoplasms dissected into indolent, leukaemic and unfavourable subtypes by computational clustering of haematopoietic stem and progenitor cells
Margot F. van Spronsen
Sofie Van Gassen
Carolien Duetz
Theresia M. Westers
Yvan Saeys
Arjan A. van de Loosdrecht
A1
Journal Article
in
LEUKEMIA
2024
Optimizing computational cytometry tools for clinical applications
Artuur Couckuyt
Yvan Saeys
Tessa Kerre
Dissertation
2024
Pattern or Artifact? Interactively Exploring Embedding Quality with TRACE
Edith Heiter
Liesbet Martens
Ruth Seurinck
Martin Guilliams
Tijl De Bie
Yvan Saeys
Jefrey Lijffijt
U
Conference
2024
SCIP: A scalable, reproducible, and open-source pipeline for morphological profiling image cytometry and microscopy data.
Maxim Lippeveld
Daniel Peralta Cámara
Andrew Filby
Yvan Saeys
U
Journal Article
in
Cytometry. Part A : the journal of the International Society for Analytical Cytology
2024
SpatialData : an open and universal data framework for spatial omics
Luca Marconato
Giovanni Palla
Kevin A. Yamauchi
Isaac Virshup
Elyas Heidari
Tim Treis
Wouter-Michiel Vierdag
Marcella Toth
Sonja Stockhaus
Rahul B. Shrestha
et al.
A1
Journal Article
in
NATURE METHODS
2024
Spotless, a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics
Chananchida Sang-aram
Robin Browaeys
Ruth Seurinck
Yvan Saeys
A1
Journal Article
in
ELIFE
2024
Uncertainty-aware single-cell annotation with a hierarchical reject option
Lauren Theunissen
Thomas Mortier
Yvan Saeys
Willem Waegeman
A1
Journal Article
in
BIOINFORMATICS
2024
2023
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state
Sandra Van Lint
Alexander Van Parys
Bram Van Den Eeckhout
Niels Vandamme
Stephane Plaisance
Annick Verhee
Dominiek Catteeuw
Elke Rogge
Jennifer De Geest
Nele Vanderroost
et al.
A1
Journal Article
in
MOLECULAR CANCER
2023
A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis
Trang Hieu Nguyen
Louis Thiers
Alex Van Moerkercke
Yuechen Bai
Patricia Fernandez Calvo
Max Minne
Thomas Depuydt
Maite Colinas Martinez
Kevin Verstaen
Gert Van Isterdael
et al.
A1
Journal Article
in
NATURE PLANTS
2023
A robust pipeline for high-content, high-throughput immunophenotyping reveals age- and genetics-dependent changes in blood leukocytes
Thomas Liechti
Sofie Van Gassen
Margaret Beddall
Reid Ballard
Yaser Iftikhar
Renguang Du
Thiagarajan Venkataraman
David Novák
Massimo Mangino
Stephen Perfetto
et al.
A2
Journal Article
in
CELL REPORTS METHODS
2023
Adjuvant dendritic cell-based immunotherapy after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with malignant peritoneal mesothelioma : a phase II clinical trial
Michelle Dietz
Katrien Quintelier
Job P. van Kooten
Nadine L. de Boer
Madelief Vink
Alexandra R. M. Brandt-Kerkhof
Cornelis Verhoef
Yvan Saeys
Joachim G. J. V. Aerts
Marcella Willemsen
et al.
A1
Journal Article
in
JOURNAL FOR IMMUNOTHERAPY OF CANCER
2023
Cell type-specific attenuation of brassinosteroid signaling precedes stomatal asymmetric cell division
Kim Eunji
Cheng Zhang
Boyu Guo
Thomas Eekhout
Anaxi Houbaert
Jos Wendrich
Niels Vandamme
Manish Tiwari
Claire Simon--Vezo
Isabelle Vanhoutte
et al.
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2023
Dysregulation of developmental and cell type-specific expression of glycoconjugates on hematopoietic cells : a new characteristic of myelodysplastic neoplasms (MDS)
Margot F. van Spronsen
Sophie Horrevorts
Claudia Cali
Theresia M. Westers
Sofie Van Gassen
Yvan Saeys
Sandra J. van Vliet
Yvette van Kooyk
Arjan A. van de Loosdrecht
A1
Journal Article
in
LEUKEMIA
2023
Efficient approximation of asymmetric Shapley values using functional decomposition
Arne Gevaert
Anna Saranti
Andreas Holzinger
Yvan Saeys
C1
Conference
2023
Ferroptosis and pyroptosis signatures in critical COVID-19 patients
Cédric Peleman
Samya Van Coillie
Symen Ligthart
Sze Men Choi
Jan De Waele
Pieter Depuydt
Dominique Benoit
Hannah Schaubroeck
Sven M. Francque
Karolien Dams
et al.
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2023
Functions of the RIP kinase family members in the skin
Corinne Urwyler
Giel Tanghe
Michael Devos
Paco Hulpiau
Yvan Saeys
Wim Declercq
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2023
Gut inflammation in axial spondyloarthritis patients is characterized by a marked type 17 skewed mucosal innate‐like T cell signature
Céline Mortier
Katrien Quintelier
Ann-Sophie De Craemer
Thomas Renson
Liselotte Deroo
Emilie Dumas
Eveline Verheugen
Julie Coudenys
Tine Decruy
Zuzanna Łukasik
et al.
A1
Journal Article
in
ARTHRITIS & RHEUMATOLOGY
2023
Improving the robustness of deep neural networks to adversarial perturbations
Jonathan Peck
Yvan Saeys
Bart Goossens
Dissertation
2023
LXR signaling controls homeostatic dendritic cell maturation
Victor Bosteels
Sandra Maréchal
Clint De Nolf
Sofie Rennen
Jonathan Maelfait
Simon Tavernier
Jessica Vetters
Evelien Van De Velde
Farzaneh Fayazpour
Kim Deswarte
et al.
A1
Journal Article
in
SCIENCE IMMUNOLOGY
2023
Machine learning pipeline for predicting bone marrow edema along the sacroiliac joints on magnetic resonance imaging
Joris Roels
Ann-Sophie De Craemer
Thomas Renson
Manouk de Hooge
Arne Gevaert
Thomas Van Den Berghe
Lennart Jans
Nele Herregods
Philippe Carron
Filip Van den Bosch
et al.
A1
Journal Article
in
ARTHRITIS & RHEUMATOLOGY
2023
Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability
Anthony Sonrel
Almut Luetge
Charlotte Soneson
Izaskun Mallona
Pierre-Luc Germain
Sergey Knyazev
Jeroen Gilis
Reto Gerber
Ruth Seurinck
Dominique Paul
et al.
A1
Journal Article
in
GENOME BIOLOGY
2023
Modeling intercellular communication from transcriptomics data by linking ligands to target genes
Robin Browaeys
Yvan Saeys
Dissertation
2023
MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data
Robin Browaeys
Jeroen Gilis
Chananchida Sang-aram
Pieter De Bleser
Levi Hoste
Simon Tavernier
Diether Lambrechts
Ruth Seurinck
Yvan Saeys
Preprint
2023
QT–GWAS : a novel method for unveiling biosynthetic loci affecting qualitative metabolic traits
Marlies Brouckaert
Meng Peng
René Höfer
Ilias El Houari
Chiarina Darrah
Veronique Storme
Yvan Saeys
Ruben Vanholme
Geert Goeminne
Vitaliy I. Timokhin
et al.
A1
Journal Article
in
MOLECULAR PLANT
2023
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma
Dena Panovska
Pouya Nazari
Basiel Cole
Pieter-Jan Creemers
Marleen Derweduwe
Lien Solie
Sofie Van Gassen
Annelies Claeys
Tatjana Verbeke
Elizabeth F. Cohen
et al.
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2023
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs
Beatriz F. Côrte-Real
Ibrahim Hamad
Rebeca Arroyo Hornero
Sabrina Geisberger
Joris Roels
Lauren Van Zeebroeck
Aleksandra Dyczko
Marike W. van Gisbergen
Henry Kurniawan
Allon Wagner
et al.
A1
Journal Article
in
CELL METABOLISM
2023
2022
A cellular hierarchy in melanoma uncouples growth and metastasis
Panagiotis Karras
Ignacio Bordeu
Joanna Pozniak
Ada Nowosad
Cecilia Pazzi
Nina Van Raemdonck
Ewout Landeloos
Yannick Van Herck
Dennis Pedri
Greet Bervoets
et al.
A1
Journal Article
in
NATURE
2022
A machine learning pipeline for prediction of bone marrow oedema along the sacroiliac joints on magnetic resonance imaging
Joris Roels
Ann-Sophie De Craemer
Thomas Renson
Manouk de Hooge
Arne Gevaert
Lennart Jans
Nele Herregods
Thomas Van Den Berghe
Philippe Carron
Filip Van den Bosch
et al.
C3
Conference
2022
An introduction to information technology for lawyers
Yvan Saeys
Bookchapter
in
An introduction to law & technology
2022
Angiogenesis goes computational : the future way forward to discover new angiogenic targets?
Abhishek Subramanian
Pooya Zakeri
Mira Mousa
Halima Alnaqbi
Fatima Yousif Alshamsi
Leo Bettoni
Ernesto Damiani
Habiba Alsafar
Yvan Saeys
Peter Carmeliet
A1
Journal Article
in
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2022
BioSegment : active learning segmentation for 3D electron microscopy imaging
Benjamin Rombaut
Joris Roels
Yvan Saeys
C1
Conference
2022
CARD14 signalling ensures cell survival and cancer associated gene expression in prostate cancer cells
Domien Vanneste
Jens Staal
Mira Haegman
Yasmine Driege
Marieke Carels
Elien Van Nuffel
Pieter De Bleser
Yvan Saeys
Rudi Beyaert
Inna Afonina
A1
Journal Article
in
BIOMEDICINES
2022
CD8 memory precursor cell generation is a continuous process
Helena Todorov
Margaux Prieux
Daphne Laubreton
Matteo Bouvier
Shaoying Wang
Simon de Bernard
Christophe Arpin
Robrecht Cannoodt
Wouter Saelens
Arnaud Bonnaffoux
et al.
A1
Journal Article
in
ISCIENCE
2022
Cell type-specific attenuation of brassinosteroid signalling drives stomatal asymmetric cell division
Kim Eunji
Cheng Zhang
Boyu Guo
Thomas Eekhout
Anaxi Houbaert
Jos Wendrich
Niels Vandamme
Manish Tiwari
Claire Simon--Vezo
Isabelle Vanhoutte
et al.
Preprint
2022
Challenges in translational machine learning
Artuur Couckuyt
Ruth Seurinck
Annelies Emmaneel
Katrien Quintelier
David Novák
Sofie Van Gassen
Yvan Saeys
A1
Journal Article
in
HUMAN GENETICS
2022
Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq
Viacheslav Mylka
Irina Matetovici
Suresh Poovathingal
Jeroen Aerts
Niels Vandamme
Ruth Seurinck
Kevin Verstaen
Gert Hulselmans
Silvie van den Hoecke
Isabelle Scheyltjens
et al.
A1
Journal Article
in
GENOME BIOLOGY
2022
Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition
Johannes Bues
Marjan Biocanin
Joern Pezoldt
Riccardo Dainese
Antonius Chrisnandy
Saba Rezakhani
Wouter Saelens
Vincent Gardeux
Revant Gupta
Rita Sarkis
et al.
A1
Journal Article
in
NATURE METHODS
2022
Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer
Nele Loret
Niels Vandamme
Jordy De Coninck
Joachim Taminau
Kato De Clercq
Gillian Blancke
Sven Jonckheere
Steven Goossens
Kelly Lemeire
Sofie De Prijck
et al.
A1
Journal Article
in
MOLECULAR CANCER RESEARCH
2022
Evaluating feature attribution methods in the image domain
Arne Gevaert
Axel-Jan Rousseau
Thijs Becker
Dirk Valkenborg
Tijl De Bie
Yvan Saeys
Preprint
2022
Improving diagnosis of primary immunodeficiencies using computional cytometry
Annelies Emmaneel
Yvan Saeys
Sofie Van Gassen
Dissertation
2022
Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures
Laetitia Dubouchet
Helena Todorov
Ruth Seurinck
Nicolas Vallet
Sofie Van Gassen
Aurelien Corneau
Catherine Blanc
Habib Zouali
Anne Boland
Jean-Francois Deleuze
et al.
A1
Journal Article
in
SCIENCE TRANSLATIONAL MEDICINE
2022
PDD-SHAP: Fast Approximations for Shapley Values using Functional Decomposition
Arne Gevaert
Yvan Saeys
C1
Conference
2022
PeacoQC : peak-based selection of high quality cytometry data
Annelies Emmaneel
Katrien Quintelier
Dorine Sichien
Paulina Rybakowska
Concepcion Maranon
Marta E. Alarcon-Riquelme
Gert Van Isterdael
Sofie Van Gassen
Yvan Saeys
A1
Journal Article
in
CYTOMETRY PART A
2022
Protocol for large scale whole blood immune monitoring by mass cytometry and Cyto Quality Pipeline
P Rybakowska
Sofie Van Gassen
J Martorell Marugán
Katrien Quintelier
Yvan Saeys
ME Alarcón-Riquelme
C Marañón
A2
Journal Article
in
STAR PROTOCOLS
2022
Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues
Isabelle Scheyltjens
Hannah Van Hove
Karen De Vlaminck
Daliya Kancheva
Jonathan Bastos
Monica Vara-Perez
Ana Rita Pombo Antunes
Liesbet Martens
Charlotte Scott
Jo Van Ginderachter
et al.
A1
Journal Article
in
NATURE PROTOCOLS
2022
Single-cell transcriptomics sheds light on the identity and metabolism of developing leaf cells
Rubén Tenorio Berrio
Kevin Verstaen
Niels Vandamme
Julie Pevernagie
Ignacio Achón
Julie Van Duyse
Gert Van Isterdael
Yvan Saeys
Lieven De Veylder
Dirk Inzé
et al.
A1
Journal Article
in
PLANT PHYSIOLOGY
2022
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
Martin Guilliams
Johnny Bonnardel
Birthe Haest
Bart Vanderborght
Camille Wagner
Anneleen Remmerie
Anna Bujko
Liesbet Martens
Tinne Thoné
Robin Browaeys
et al.
A1
Journal Article
in
CELL
2022
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Levi Hoste
Lisa Roels
Leslie Naesens
Victor Bosteels
Stijn Vanhee
Sam Dupont
Cédric Bosteels
Robin Browaeys
Niels Vandamme
Kevin Verstaen
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2022
Targeting ferroptosis protects against experimental (multi)organ dysfunction and death
Samya Van Coillie
Emily Van San
Ines Goetschalckx
Bartosz Wiernicki
Banibrata Mukhopadhyay
Wulf Tonnus
Sze Men Choi
Ria Roelandt
Catalina Dumitrascu
Ludwig Lamberts
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2022
The Euroflow PID Orientation Tube in the diagnostic workup of primary immunodeficiency : daily practice performance in a tertiary university hospital
Jana Neirinck
Annelies Emmaneel
Malicorne Buysse
Jan Philippé
Sofie Van Gassen
Yvan Saeys
Xavier Bossuyt
Stefanie De Buyser
Mirjam van der Burg
Martin Perez-Andres
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
The curse revisited : when are distances informative for the ground truth in noisy high-dimensional data?
Robin Vandaele
Bo Kang
Tijl De Bie
Yvan Saeys
P1
Conference
2022
Topologically regularized data embeddings
Robin Vandaele
Bo Kang
Jefrey Lijffijt
Tijl De Bie
Yvan Saeys
C1
Conference
2022
2021
A study on the calibration of fingerprint classifiers
Daniel Peralta Cámara
Lin Tang
Maxim Lippeveld
Yvan Saeys
P1
Conference
2021
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism
Leen Catrysse
Bastiaan Maes
Parul Mehrotra
Arne Martens
Esther Hoste
Liesbet Martens
Christian Maueröder
Anneleen Remmerie
Anna Bujko
Karolina Slowicka
et al.
A1
Journal Article
in
CELL REPORTS
2021
Advances and opportunities in single-cell transcriptomics for plant research
Carolin Seyfferth
Jim Renema
Jos Wendrich
Thomas Eekhout
Ruth Seurinck
Niels Vandamme
Bernhard Blob
Yvan Saeys
Yrjo Helariutta
Kenneth D. Birnbaum
et al.
A1
Journal Article
in
ANNUAL REVIEW OF PLANT BIOLOGY
2021
Analyzing high-dimensional cytometry data using FlowSOM
Katrien Quintelier
Artuur Couckuyt
Annelies Emmaneel
Joachim Aerts
Yvan Saeys
Sofie Van Gassen
A1
Journal Article
in
NATURE PROTOCOLS
2021
Cell-by-cell dissection of phloem development links a maturation gradient to cell specialization
Pawel Roszak
Jung-ok Heo
Bernhard Blob
Koichi Toyokura
Yuki Sugiyama
Maria Angels de Luis Balaguer
Winnie W. Y. Lau
Fiona Hamey
Jacopo Cirrone
Ewelina Madej
et al.
A1
Journal Article
in
SCIENCE
2021
Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes
Carolien Duetz
Sofie Van Gassen
Theresia M. Westers
Margot F. van Spronsen
Costa Bachas
Yvan Saeys
Arjan A. van de Loosdrecht
A1
Journal Article
in
CYTOMETRY PART A
2021
DALI (Diversity AnaLysis Interface) : a novel tool for the integrated analysis of multimodal single cell RNAseq data and immune receptor profiling
Kevin Verstaen
Inés Lammens
Jana Roels
Yvan Saeys
Bart Lambrecht
Niels Vandamme
Stijn Vanhee
Preprint
2021
Data processing workflow for large-scale immune monitoring studies by mass cytometry
Paulina Rybakowska
Sofie Van Gassen
Katrien Quintelier
Yvan Saeys
Marta E. Alarcón-Riquelme
Concepción Marañón
A1
Journal Article
in
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2021
Fibrotic enzymes modulate wound-induced skin tumorigenesis
Lisette Van Hove
Kim Lecomte
Jana Roels
Niels Vandamme
Hanna-Kaisa Vikkula
Isabelle Hoorens
Katia Ongenae
Tino Hochepied
Giacomo Donati
Yvan Saeys
et al.
A1
Journal Article
in
EMBO REPORTS
2021
Graph approximations to geodesics on metric graphs
Robin Vandaele
Yvan Saeys
Tijl De Bie
P1
Conference
2021
High dimensional profiling identifies specific immune types along the recovery trajectories of critically ill COVID19 patients
P. A. Penttila
Sofie Van Gassen
D. Panovska
L. Vanderbeke
Y. Van Herck
Katrien Quintelier
Annelies Emmaneel
J. Filtjens
B. Malengier-Devlies
K. Ahmadzadeh
et al.
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2021
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
Matthias Vanderkerken
Antonio Pires da Silva Baptista
Marco De Giovanni
Satoshi Fukuyama
Robin Browaeys
Charlotte Scott
Paula S. Norris
Gerard Eberl
James P. Di Santo
Eric Vivier
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2021
Immune monitoring in melanoma and urothelial cancer patients treated with anti-PD-1 immunotherapy and SBRT discloses tumor specific immune signatures
Annabel Meireson
Simon Tavernier
Sofie Van Gassen
Nora Sundahl
Annelies Demeyer
Mathieu Spaas
Vibeke Kruse
Liesbeth Ferdinande
Jo Van Dorpe
Benjamin Hennart
et al.
A1
Journal Article
in
CANCERS
2021
Macrophages are metabolically heterogeneous within the tumor microenvironment
Xenia Geeraerts
Juan Fernandez-Garcia
Felix J. Hartmann
Kyra E. de Goede
Liesbet Martens
Yvon Elkrim
Ayla Debraekeleer
Benoit Stijlemans
Anke Vandekeere
Gianmarco Rinaldi
et al.
A1
Journal Article
in
CELL REPORTS
2021
Maize specialized metabolome networks reveal organ-preferential mixed glycosides
Sandrien Desmet
Yvan Saeys
Kevin Verstaen
Rebecca Dauwe
Hoon Kim
Claudiu Niculaes
Atsushi Fukushima
Geert Goeminne
Ruben Vanholme
John Ralph
et al.
A1
Journal Article
in
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2021
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
L. Vanderbeke
P. Van Mol
Y. Van Herck
F. De Smet
S. Humblet-Baron
K. Martinod
A. Antoranz
I. Arijs
B. Boeckx
F. M. Bosisio
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
Non-cell autonomous and spatiotemporal signaling from a tissue organizer orchestrates root vascular development
Baojun Yang
Max Minne
Federica Brunoni
Lenka Plačková
Ivan Petřík
Yanbiao Sun
Jonah Nolf
Wouter Smet
Kevin Verstaen
Jos Wendrich
et al.
A1
Journal Article
in
NATURE PLANTS
2021
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
Esther Hoste
Kim Lecomte
Karl Annusver
Niels Vandamme
Jana Roels
Sophia Maschalidi
Lien Verboom
Hanna-Kaisa Vikkula
Mozes Sze
Lisette Van Hove
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
Recent advances in trajectory inference from single-cell omics data
Louise Deconinck
Robrecht Cannoodt
Wouter Saelens
Bart Deplancke
Yvan Saeys
A2
Journal Article
in
CURRENT OPINION IN SYSTEMS BIOLOGY
2021
SCMFTS : scalable and distributed complexity measures and features for univariate and multivariate time series in Big Data environments
Francisco J. Baldan
Daniel Peralta Cámara
Yvan Saeys
Jose M. Benitez
A1
Journal Article
in
INTERNATIONAL JOURNAL OF COMPUTATIONAL INTELLIGENCE SYSTEMS
2021
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
Ana Rita Pombo Antunes
Isabelle Scheyltjens
Francesca Lodi
Julie Messiaen
Asier Antoranz
Johnny Duerinck
Daliya Kancheva
Liesbet Martens
Karen De Vlaminck
Hannah Van Hove
et al.
A1
Journal Article
in
NATURE NEUROSCIENCE
2021
Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells
Robrecht Cannoodt
Wouter Saelens
Louise Deconinck
Yvan Saeys
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
Stabilization of human whole blood samples for multicenter and retrospective immunophenotyping studies
Paulina Rybakowska
Catalina Burbano
Sofie Van Gassen
Nieves Varela
Rocio Aguilar-Quesada
Yvan Saeys
Marta E. Alarcon-Riquelme
Concepcion Maranon
A1
Journal Article
in
CYTOMETRY PART A
2021
Stable topological signatures for metric trees through graph approximations
Robin Vandaele
Bastian Rieck
Yvan Saeys
Tijl De Bie
A1
Journal Article
in
PATTERN RECOGNITION LETTERS
2021
Targeting ferroptosis protects against multiorgan dysfunction and death
Tom Vanden Berghe
Samya Van Coillie
Ines Goetschalckx
Bartosz Wiernicki
Banibrata Mukhopadhyay
Wulf Tonnus
Emily Van San
Sze Men Choi
Ria Roelandt
Catalina Dumitrascu
et al.
Preprint
2021
The RNA Atlas expands the catalog of human non-coding RNAs
Lucia Lorenzi
Hua-Sheng Chiu
Francisco Avila Cobos
Stephen Gross
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
et al.
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2021
The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)
Lucia Lorenzi
Hua-Sheng Chiu
Francisco Avila Cobos
Stephen Gross
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
et al.
Correction
2021
2020
A cell atlas of human thymic development defines T cell repertoire formation
Jong-Eun Park
Rachel A. Botting
Cecilia Domínguez Conde
Dorin-Mirel Popescu
Marieke Lavaert
Daniel J. Kunz
Issac Goh
Emily Stephenson
Roberta Ragazzini
Elizabeth Tuck
et al.
A1
Journal Article
in
SCIENCE
2020
A scalable SCENIC workflow for single-cell gene regulatory network analysis
Bram van de Sande
Christopher Flerin
Kristofer Davie
Maxime De Waegeneer
Gert Hulselmans
Sara Aibar
Ruth Seurinck
Wouter Saelens
Robrecht Cannoodt
Quentin Rouchon
et al.
A1
Journal Article
in
NATURE PROTOCOLS
2020
An interactive ImageJ plugin for semi-automated image denoising in electron microscopy
Joris Roels
Frank Vernaillen
Anna Kremer
Amanda Gonçalves
Jan Aelterman
Hiep Luong
Bart Goossens
Wilfried Philips
Saskia Lippens
Yvan Saeys
A1
Journal Article
in
NATURE COMMUNICATIONS
2020
Asynchronous processing for latent fingerprint identification on heterogeneous CPU-GPU systems
Andres J. Sanchez-Fernandez
Luis F. Romero
Daniel Peralta Cámara
Miguel Angel Medina-Perez
Yvan Saeys
Francisco Herrera
Siham Tabik
A1
Journal Article
in
IEEE ACCESS
2020
Automated learning of biologically relevant features from primary sequence using convolutional neural networks
Jasper Zuallaert
Wesley De Neve
Nico Callewaert
Yvan Saeys
Dissertation
2020
Calibrated multi-probabilistic prediction as a defense against adversarial attacks
Jonathan Peck
Bart Goossens
Yvan Saeys
C1
Conference
2020
Classification of human white blood cells using machine learning for stain-free imaging flow cytometry
Maxim Lippeveld
Carly Knill
Emma Ladlow
Andrew Fuller
Louise J Michaelis
Yvan Saeys
Andrew Filby
Daniel Peralta Cámara
A1
Journal Article
in
CYTOMETRY PART A
2020
CytoNorm : a normalization algorithm for cytometry data
Sofie Van Gassen
Brice Gaudilliere
Martin S Angst
Yvan Saeys
Nima Aghaeepour
A1
Journal Article
in
CYTOMETRY PART A
2020
Detecting adversarial manipulation using inductive Venn-ABERS predictors
Jonathan Peck
Bart Goossens
Yvan Saeys
A1
Journal Article
in
NEUROCOMPUTING
2020
Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection
Cédric Bosteels
Katrijn Neyt
Manon Vanheerswynghels
Mary van Helden
Dorine Sichien
Nincy Debeuf
Sofie De Prijck
Victor Bosteels
Niels Vandamme
Liesbet Martens
et al.
A1
Journal Article
in
IMMUNITY
2020
Integrated scRNA-seq identifies human postnatal thymus seeding progenitors and regulatory dynamics of differentiating immature thymocytes
Marieke Lavaert
Kai Ling Liang
Niels Vandamme
Jong-Eun Park
Juliette Roels
Monica S. Kowalczyk
Bo Li
Orr Ashenberg
Marcin Tabaka
Danielle Dionne
et al.
A1
Journal Article
in
IMMUNITY
2020
Mining topological structure in graphs through forest representations
Robin Vandaele
Yvan Saeys
Tijl De Bie
A1
Journal Article
in
JOURNAL OF MACHINE LEARNING RESEARCH
2020
NicheNet : modeling intercellular communication by linking ligands to target genes
Robin Browaeys
Wouter Saelens
Yvan Saeys
A1
Journal Article
in
NATURE METHODS
2020
OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis
Lien Verboom
Arne Martens
Dario Priem
Esther Hoste
Mozes Sze
Hanna-Kaisa Vikkula
Lisette Van Hove
Sofie Voet
Jana Roels
Jonathan Maelfait
et al.
A1
Journal Article
in
CELL REPORTS
2020
Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver
Anneleen Remmerie
Liesbet Martens
Tinne Thoné
Angela Castoldi
Ruth Seurinck
Benjamin Pavie
Joris Roels
Bavo Vanneste
Sofie De Prijck
Mathias Vanhockerhout
et al.
A1
Journal Article
in
IMMUNITY
2020
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury
Elke Ydens
Lukas Amann
Bob Asselbergh
Charlotte Scott
Liesbet Martens
Dorine Sichien
Omar Mossad
Thomas Blank
Sofie De Prijck
Donovan Low
et al.
A1
Journal Article
in
NATURE NEUROSCIENCE
2020
Regional image perturbation reduces Lp norms of adversarial examples while maintaining model-to-model transferability
Utku Özbulak
Jonathan Peck
Wesley De Neve
Bart Goossens
Yvan Saeys
Arnout Van Messem
C1
Conference
2020
Robust unsupervised dimensionality reduction based on feature clustering for single-cell imaging data
Daniel Peralta Cámara
Yvan Saeys
A1
Journal Article
in
APPLIED SOFT COMPUTING
2020
Special issue on machine learning for single cell cata
Yvan Saeys
Greg Finak
Editorial material
2020
Structure learning to unravel mechanisms of the immune system
Helena Todorov
Yvan Saeys
Jacqueline Marvel
Dissertation
2020
TinGa : fast and flexible trajectory inference with Growing Neural Gas
Helena Todorov
Robrecht Cannoodt
Wouter Saelens
Yvan Saeys
A1
Journal Article
in
BIOINFORMATICS
2020
Topological inference in graphs and images
Robin Vandaele
Tijl De Bie
Yvan Saeys
Dissertation
2020
Trajectory-based differential expression analysis for single-cell sequencing data
Koen Van den Berge
Hector Roux de Bézieux
Kelly Street
Wouter Saelens
Robrecht Cannoodt
Yvan Saeys
Sandrine Dudoit
Lieven Clement
A1
Journal Article
in
NATURE COMMUNICATIONS
2020
Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions
Jos Wendrich
Baojun Yang
Niels Vandamme
Kevin Verstaen
Wouter Smet
Celien Van de Velde
Max Minne
Brecht Wybouw
Eliana Mor
Helena Arents
et al.
A1
Journal Article
in
SCIENCE
2020
2019
A comparison of single-cell trajectory inference methods
Wouter Saelens
Robrecht Cannoodt
Helena Todorov
Yvan Saeys
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2019
A computational pipeline for the diagnosis of CVID patients
Annelies Emmaneel
Delfien Bogaert
Sofie Van Gassen
Simon Tavernier
Melissa Dullaers
Filomeen Haerynck
Yvan Saeys
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2019
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation
Simon Tavernier
V Athanasopoulos
PATRICK VERLOO
G Behrens
Jens Staal
Delfien Bogaert
Leslie Naesens
Marieke De Bruyne
Sofie Van Gassen
Eef Parthoens
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Hannah Van Hove
Liesbet Martens
Isabelle Scheyltjens
Karen De Vlaminck
Ana Rita Pombo Antunes
Sofie De Prijck
Niels Vandamme
Sebastiaan De Schepper
Gert Van Isterdael
Charlotte Scott
et al.
A1
Journal Article
in
NATURE NEUROSCIENCE
2019
Computational approaches for high-throughput single-cell data analysis
Helena Todorov
Yvan Saeys
A1
Journal Article
in
FEBS JOURNAL
2019
Detecting adversarial examples with inductive Venn-ABERS predictors
Jonathan Peck
Bart Goossens
Yvan Saeys
C1
Conference
2019
Developing and benchmarking methods for analysing transcriptomics data
Wouter Saelens
Yvan Saeys
Bart Lambrecht
Dissertation
2019
Distillation of Deep Reinforcement Learning Models using Fuzzy Inference Systems
Arne Gevaert
Jonathan Peck
Yvan Saeys
C3
Conference
2019
Distributed, numerically stable distance and covariance computation with MPI for extremely large datasets
Daniel Peralta Cámara
Yvan Saeys
P1
Conference
2019
Domain adaptive segmentation in volume electron microscopy imaging
Joris Roels
Julian Hennies
Yvan Saeys
Wilfried Philips
Anna Kreshuk
P1
Conference
2019
Dynbenchmark : accuracy, scalability, robustness and usability of single-cell trajectory inference methods
Robrecht Cannoodt
Wouter Saelens
Helena Todorov
Yvan Saeys
C3
Conference
2019
Epithelial HMGB1 delays skin wound healing and drives tumor initiation by priming neutrophils for NET formation
Esther Hoste
Christian Maueröder
Lisette Van Hove
Leen Catrysse
Hanna-Kaisa Vikkula
Mozes Sze
Bastiaan Maes
Dyah Karjosukarso
Liesbet Martens
Amanda Gonçalves
et al.
A1
Journal Article
in
CELL REPORTS
2019
Essential guidelines for computational method benchmarking
Lukas M Weber
Wouter Saelens
Robrecht Cannoodt
Charlotte Soneson
Alexander Hapfelmeier
Paul P Gardner
Anne-Laure Boulesteix
Yvan Saeys
Mark D Robinson
A1
Journal Article
in
GENOME BIOLOGY
2019
Geautomatiseerde segmentatie van 3D-elektronenmicroscopiebeelden
Joris Roels
Wilfried Philips
Yvan Saeys
Dissertation
2019
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Andrea Cossarizza
Hyun-Dong Chang
Andreas Radbruch
Andreas Acs
Dieter Adam
Sabine Adam-Klages
William W Agace
Nima Aghaeepour
Muebeccel Akdis
Matthieu Allez
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF IMMUNOLOGY
2019
Investigating the biological relevance in trained embedding representations of protein sequences
Jasper Zuallaert
Xiaoyong Pan
Yvan Saeys
Xi Wang
Wesley De Neve
C1
Conference
2019
Local topological data analysis to uncover the global structure of data approaching graph-structured topologies
Robin Vandaele
Tijl De Bie
Yvan Saeys
C1
Conference
2019
Mining the enriched subgraphs for specific vertices in a biological graph
Pieter Meysman
Yvan Saeys
Ehsan Sabaghian
Wout Bittremieux
Yves Van de Peer
Bart Goethals
Kris Laukens
A1
Journal Article
in
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS
2019
Modelling single-cell dynamics with trajectories and gene regulatory networks
Robrecht Cannoodt
Yvan Saeys
Katleen De Preter
Dissertation
2019
Network inference from single-cell transcriptomic data
Helena Todorov
Robrecht Cannoodt
Wouter Saelens
Yvan Saeys
Bookchapter
in
Gene regulatory networks : methods and protocols
2019
Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
Hanne Dubois
Frederic Sorgeloos
Soroush T. Sarvestani
Liesbet Martens
Yvan Saeys
Jason M. Mackenzie
Mohamed Lamkanfi
Geert van Loo
Ian Goodfellow
Andy Wullaert
A1
Journal Article
in
PLOS PATHOGENS
2019
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients
Koen Venken
Peggy Jacques
Céline Mortier
Mark E. Labadia
Tine Decruy
Julie Coudenys
Kathleen Hoyt
Anita L. Wayne
Robert Hughes
Michael Turner
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells
Christopher Andrew Tibbitt
Julian Mario Stark
Liesbet Martens
Junjie Ma
Jeff Eron Mold
Kim Deswarte
Ganna Oliynyk
Xiaogang Feng
Bart Lambrecht
Pieter De Bleser
et al.
A1
Journal Article
in
IMMUNITY
2019
Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche
Johnny Bonnardel
Wouter T'Jonck
Djoere Gaublomme
Robin Browaeys
Charlotte Scott
Liesbet Martens
Bavo Vanneste
Sofie De Prijck
Sergei A Nedospasov
Anna Kremer
et al.
A1
Journal Article
in
IMMUNITY
2019
The boundary coefficient : a vertex measure for visualizing and finding structure in weighted graphs
Robin Vandaele
Yvan Saeys
Tijl De Bie
C1
Conference
2019
Unravelling gene functions in Arabidopsis thaliana by means of network biology and machine learning
Ehsan Sabaghian
Yves Van de Peer
Yvan Saeys
Dissertation
2019
Weight selection strategies for ordered weighted average based fuzzy rough sets
Sarah Vluymans
Neil Mac Parthalain
Chris Cornelis
Yvan Saeys
A1
Journal Article
in
INFORMATION SCIENCES
2019
2018
A comprehensive evaluation of module detection methods for gene expression data
Wouter Saelens
Robrecht Cannoodt
Yvan Saeys
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
An overview of state-of-the-art image restoration in electron microscopy
Joris Roels
Jan Aelterman
Hiep Luong
Saskia Lippens
Aleksandra Pizurica
Yvan Saeys
Wilfried Philips
A1
Journal Article
in
JOURNAL OF MICROSCOPY
2018
Ancient origin of the CARD-coiled coil/Bcl10/MALT1-like paracaspase signaling complex indicates unknown critical functions
Jens Staal
Yasmine Driege
Mira Haegman
Alice Borghi
Paco Hulpiau
Laurens Lievens
Ismail Sahin Gül
Srividhya Sundararaman Iyer
Amanda Gonçalves
Ineke Dhondt
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2018
Dealing with imbalanced and weakly labelled data in machine learning using fuzzy and rough set methods
Sarah Vluymans
Yvan Saeys
Chris Cornelis
Dissertation
2018
Dynamic affinity-based classification of multi-class imbalanced data with one-versus-one decomposition : a fuzzy rough set approach
Sarah Vluymans
Alberto Fernández
Yvan Saeys
Chris Cornelis
Francisco Herrera
A1
Journal Article
in
KNOWLEDGE AND INFORMATION SYSTEMS
2018
GC content of Early Metazoan genes and its impact on gene expression levels in mammalian cell lines
Ismail Sahin Gül
Jens Staal
Paco Hulpiau
Evi De Keuckelaere
Kai Kamm
Tom Deroo
Ellen Sanders
Katrien Staes
Yasmine Driege
Yvan Saeys
et al.
A1
Journal Article
in
GENOME BIOLOGY AND EVOLUTION
2018
Identifying and classifying protein coding gene polymorphisms between laboratory mouse strains and investigating glucocorticoid actions in sepsis models
Steven Timmermans
Claude Libert
Yvan Saeys
Dissertation
2018
IncGraph : incremental graphlet counting for topology optimisation
Robrecht Cannoodt
Joeri Ruyssinck
Jana Ramon
Katleen De Preter
Yvan Saeys
A1
Journal Article
in
PLOS ONE
2018
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Isabelle Cambré
Djoere Gaublomme
Arne Burssens
Peggy Jacques
Nadia Schryvers
Amélie De Muynck
Leander Meuris
Stijn Lambrecht
Shea Carter
Pieter De Bleser
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
Multi-label classification using a fuzzy rough neighborhood consensus
Sarah Vluymans
Chris Cornelis
Francisco Herrera
Yvan Saeys
A1
Journal Article
in
INFORMATION SCIENCES
2018
Myeloid cell heterogeneity in cancer: not a single cell alike
Mate Kiss
Sofie Van Gassen
Kiavash Movahedi
Yvan Saeys
Damya Laoui
A1
Journal Article
in
CELLULAR IMMUNOLOGY
2018
Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells
Katrien Van Der Borght
Charlotte Scott
Liesbet Martens
Dorine Sichien
Gert Van Isterdael
Veronika Nindl
Yvan Saeys
Louis Boon
Burkhard Ludewig
Thierry Gillebert
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2018
Nanos genes and their role in development and beyond
Evi De Keuckelaere
Paco Hulpiau
Yvan Saeys
Geert Berx
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2018
On the use of convolutional neural networks for robust classification of multiple fingerprint captures
Daniel Peralta Cámara
Isaac Triguero
Salvador García
Yvan Saeys
Jose M Benitez
Francisco Herrera
A1
Journal Article
in
INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS
2018
Response to Orlova et al. 'Science not art: statistically sound methods for identifying subsets in multi-dimensional flow and mass cytometry data sets'
Yvan Saeys
Sofie Van Gassen
Bart Lambrecht
A1
Journal Article
in
NATURE REVIEWS IMMUNOLOGY
2018
SpliceRover : interpretable convolutional neural networks for improved splice site prediction
Jasper Zuallaert
Fréderic Godin
Mi Jung Kim
Arne Soete
Yvan Saeys
Wesley De Neve
A1
Journal Article
in
BIOINFORMATICS
2018
Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha
Srinath Govindarajan
Djoere Gaublomme
Renée Van der Cruyssen
Eveline Verheugen
Sofie Van Gassen
Yvan Saeys
Simon Tavernier
Takao Iwawaki
Yehudi Bloch
Savvas Savvides
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
TISRover : ConvNets learn biologically relevant features for effective translation initiation site prediction
Jasper Zuallaert
Mijung Kim
Arne Soete
Yvan Saeys
Wesley De Neve
A1
Journal Article
in
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS
2018
TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Liesbet Martens
Yvan Saeys
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
The TLX1 oncogene modules the enhancer RNA landscape in T-ALL
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Yvan Saeys
Liesbet Martens
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages
Charlotte Scott
Wouter T'Jonck
Liesbet Martens
Helena Todorov
Dorine Sichien
Bieke Soen
Johnny Bonnardel
Sofie De Prijck
Niels Vandamme
Robrecht Cannoodt
et al.
A1
Journal Article
in
IMMUNITY
2018
2017
A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties
Aline Van Acker
Konrad Gronke
Aindrila Biswas
Liesbet Martens
Yvan Saeys
Jessica Filtjens
Sylvie Taveirne
Els Van Ammel
Tessa Kerre
Patrick Matthys
et al.
A1
Journal Article
in
CELL REPORTS
2017
Computational analysis of multimorbidity between asthma, eczema and rhinitis
Daniel Aguilar
Mariona Pinart
Gerard H Koppelman
Yvan Saeys
Martijn C Nawijn
Dirkje S Postma
Mübeccel Akdis
Charles Auffray
Stéphane Ballereau
Marta Benet
et al.
A1
Journal Article
in
PLOS ONE
2017
ConTra v3 : a tool to identify transcription factor binding sites across species, update 2017
Lukasz Kreft
Arne Soete
Paco Hulpiau
Alexander Botzki
Yvan Saeys
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2017
Convolutional neural network pruning to accelerate membrane segmentation in electron microscopy
Joris Roels
Jonas De Vylder
Jan Aelterman
Yvan Saeys
Wilfried Philips
P1
Conference
2017
Coordinated functional divergence of genes after genome duplication in Arabidopsis thaliana
Riet De Smet
Ehsan Sabaghian
Zhen Li
Yvan Saeys
Yves Van de Peer
A1
Journal Article
in
PLANT CELL
2017
Development of machine learning techniques for flow cytometry data
Sofie Van Gassen
Tom Dhaene
Yvan Saeys
Dissertation
2017
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay (vol 6, 36111, 2016)
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
Correction
2017
Distributed incremental fingerprint identification with reduced database penetration rate using a hierarchical classification based on feature fusion and selection
Daniel Peralta Cámara
Isaac Triguero
Salvador García
Yvan Saeys
Jose M Benitez
Francisco Herrera
A1
Journal Article
in
KNOWLEDGE-BASED SYSTEMS
2017
Evolution and diversity of cadherins and catenins
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2017
Interpretable convolutional neural networks for effective translation initiation site prediction
Jasper Zuallaert
Mi Jung Kim
Yvan Saeys
Wesley De Neve
P1
Conference
2017
Lower bounds on the robustness to adversarial perturbations
Jonathan Peck
Joris Roels
Bart Goossens
Yvan Saeys
P1
Conference
2017
Machine learning for biological network inference
Joeri Ruyssinck
Tom Dhaene
Yvan Saeys
Dissertation
2017
Mechanisms of the Development of Allergy (MeDALL) : introducing novel concepts in allergy phenotypes
Josep M Anto
Jean Bousquet
Mubeccel Akdis
Charles Auffray
Thomas Keil
Isabelle Momas
Dirkje S Postma
Rudolf Valenta
Magnus Wickman
Anne Cambon-Thomsen
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Metazoan evolution of the armadillo repeat superfamily
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2017
Myocardial infarction primes autoreactive T cells through activation of dendritic cells
Katrien Van Der Borght
Charlotte Scott
Veronika Nindl
Ann Bouché
Liesbet Martens
Dorine Sichien
Justine Van Moorleghem
Manon Vanheerswynghels
Sofie De Prijck
Yvan Saeys
et al.
A1
Journal Article
in
CELL REPORTS
2017
Nlrp6-and ASC-dependent inflammasomes do not shape the commensal gut microbiota composition
Michail Mamantopoulos
Francesca Ronchi
Filip Van Hauwermeiren
Sara Vieira-Silva
Bahtiyar Yilmaz
Liesbet Martens
Yvan Saeys
Stefan K Drexler
Amir S Yazdi
Jeroen Raes
et al.
A1
Journal Article
in
IMMUNITY
2017
TGFβR signalling controls CD103⁺CD11b⁺ dendritic cell development in the intestine
CC Bain
J Montgomery
Charlotte Scott
JM Kel
MJH Girard-Madoux
Liesbet Martens
TFP Zangerle-Murray
J Ober-Blobaum
D Lindenbergh-Kortleve
JN Samsom
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2017
The checkpoint for agonist selection precedes conventional selection in human thymus
Greet Verstichel
David Vermijlen
Liesbet Martens
Glenn Goetgeluk
Margreet Brouwer
Nicolas Thiault
Yasmine Van Caeneghem
Stijn De Munter
Karin Weening
Sarah Bonte
et al.
A1
Journal Article
in
SCIENCE IMMUNOLOGY
2017
2016
A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes
N Aghaeepour
P Chattopadhyay
M Chikina
Tom Dhaene
Sofie Van Gassen
M Kursa
Bart Lambrecht
M Malek
GJ McLachlan
Y Qian
et al.
A1
Journal Article
in
CYTOMETRY PART A
2016
An evolutionary perspective on the necroptotic pathway
Yves Dondelinger
Paco Hulpiau
Yvan Saeys
Mathieu Bertrand
Peter Vandenabeele
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2016
Automated Membrane Detection in Electron Microscopy using Convolutional Neural Networks
Joris Roels
Jonas De Vylder
Jan Aelterman
Yvan Saeys
Wilfried Philips
C3
Conference
2016
Bayesian deconvolution of scanning electron microscopy images using point-spread function estimation and non-local regularization
Joris Roels
Jan Aelterman
Jonas De Vylder
Hiep Luong
Yvan Saeys
Wilfried Philips
P1
Conference
2016
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Charlotte Scott
Fang Zheng
Patrick De Baetselier
Liesbet Martens
Yvan Saeys
Sofie De Prijck
Saskia Lippens
Chloé Abels
Steve Schoonooghe
Geert Raes
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2016
Computational flow cytometry: helping to make sense of high-dimensional immunology data
Yvan Saeys
Sofie Van Gassen
Bart Lambrecht
A1
Journal Article
in
NATURE REVIEWS IMMUNOLOGY
2016
Computational methods for trajectory inference from single-cell transcriptomics
Robrecht Cannoodt
Wouter Saelens
Yvan Saeys
A1
Journal Article
in
EUROPEAN JOURNAL OF IMMUNOLOGY
2016
Decreasing time consumption of microscopy image segmentation through parallel processing on the GPU
Joris Roels
Jonas De Vylder
Yvan Saeys
Bart Goossens
Wilfried Philips
P1
Conference
2016
Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8
Delphine Demeestere
Eline Dejonckheere
Sophie Steeland
Paco Hulpiau
Jurgen Haustraete
Nick Devoogdt
Rielana Wichert
Christoph Becker-Pauly
Elien Van Wonterghem
Sylviane Dewaele
et al.
A1
Journal Article
in
MOLECULAR THERAPY
2016
Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
EPRENNID : an evolutionary prototype reduction based ensemble for nearest neighbor classification of imbalanced data
Sarah Vluymans
Isaac Triguero
Chris Cornelis
Yvan Saeys
A1
Journal Article
in
NEUROCOMPUTING
2016
Early TCRA rearrangements favor development of agonist selected CD8ααhi T cells in human
Greet Verstichel
Glenn Goetgeluk
Liesbet Martens
Yvan Saeys
Tessa Kerre
Hilde Cheroutre
David Vermijlen
Bart Vandekerckhove
C3
Conference
2016
Efficient analysis of mouse genome sequences reveal many nonsense variants
Sophie Steeland
Steven Timmermans
Sara Van Ryckeghem
Paco Hulpiau
Yvan Saeys
Marc Van Montagu
Roosmarijn Vandenbroucke
Claude Libert
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2016
FloReMi : flow density survival regression using minimal feature redundancy
Sofie Van Gassen
Celine Vens
Tom Dhaene
Bart Lambrecht
Yvan Saeys
A1
Journal Article
in
CYTOMETRY PART A
2016
From a biological sample to high-quality digital image representation : avoiding and restoring image artifacts through proper acquisition and image restoration
Joris Roels
Jan Aelterman
Jonas De Vylder
Hiep Luong
Saskia Lippens
Chris Guerin
Yvan Saeys
Wilfried Philips
C3
Conference
2016
Fuzzy multi-instance classifiers
Sarah Vluymans
Dánel Sánchez Tarragó
Yvan Saeys
Chris Cornelis
Francisco Herrera
A1
Journal Article
in
IEEE TRANSACTIONS ON FUZZY SYSTEMS
2016
Fuzzy rough classifiers for class imbalanced multi-instance data
Sarah Vluymans
Dánel Sánchez Tarragó
Yvan Saeys
Chris Cornelis
Francisco Herrera
A1
Journal Article
in
PATTERN RECOGNITION
2016
Fuzzy rough sets for self-labelling : an exploratory analysis
Sarah Vluymans
Neil Mac Parthaláin
Chris Cornelis
Yvan Saeys
P1
Conference
2016
GATA1-deficient dendritic cells display impaired CCL21-dependent migration toward lymph nodes due to reduced levels of polysialic acid
Maaike R Scheenstra
Iris M De Cuyper
Filipe Branco Madeira
Pieter De Bleser
Mirjam Kool
Marjolein Meinders
Mark Hoogenboezem
Erik Mu
Monika C Wolkers
Fiamma Salerno
et al.
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2016
IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively
Dorine Sichien
Charlotte Scott
Liesbet Martens
Matthias Vanderkerken
Sofie Van Gassen
Maud Plantinga
Thorsten Joeris
Sofie De Prijck
Leen Vanhoutte
Manon Vanheerswynghels
et al.
A1
Journal Article
in
IMMUNITY
2016
Improving marker gene discovery from high-dimensional single-cell snapshot data
Robrecht Cannoodt
Wouter Saelens
Katleen De Preter
Yvan Saeys
C3
Conference
2016
Improving nearest neighbor classification using Ensembles of Evolutionary Generated Prototype Subsets
Nele Verbiest
Sarah Vluymans
Chris Cornelis
Nicolás García-Pedrajas
Yvan Saeys
A1
Journal Article
in
APPLIED SOFT COMPUTING
2016
Machine learning challenges for single cell data
Sofie Van Gassen
Tom Dhaene
Yvan Saeys
P1
Conference
2016
Netter: re-ranking gene network inference predictions using structural network properties
Joeri Ruyssinck
Piet Demeester
Tom Dhaene
Yvan Saeys
A1
Journal Article
in
BMC BIOINFORMATICS
2016
Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; project no: 261357; 2010-2015
J Bousquet
JM Anto
M Akdis
C Auffray
T Keil
I Momas
DS Postma
R Valenta
M Wickman
A Cambon-Thomsen
et al.
A1
Journal Article
in
ALLERGY
2016
Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry
Ellina Macaeva
Yvan Saeys
Kevin Tabury
Ann Janssen
Arlette Michaux
Mohammed A Benotmane
Winnok De Vos
Sarah Baatout
Roel Quintens
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Semi-automated segmentation in 3D electron microscopy imaging
Joris Roels
Jan Aelterman
Jonas De Vylder
Hiep Luong
Saskia Lippens
Yvan Saeys
Wilfried Philips
C3
Conference
2016
Superpixel quality in microscopy images: the impact of noise & denoising
Joris Roels
Jonas De Vylder
Jan Aelterman
Saskia Lippens
Yvan Saeys
Wilfried Philips
P1
Conference
2016
The checkpoint for agonist selection precedes conventional selection in human thymus
Greet Verstichel
David Vermijlen
Liesbet Martens
Glenn Goetgeluk
Yvan Saeys
Hilde Cheroutre
Bart Vandekerckhove
C3
Conference
2016
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
Charlotte Scott
Bieke Soen
Liesbet Martens
Nicolas Skrypek
Wouter Saelens
Joachim Taminau
Gillian Blancke
Gert Van Isterdael
Danny Huylebroeck
Jody Haigh
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2016
Unbiased modelling of dynamic processes with single-cell RNA-sequencing
Robrecht Cannoodt
Wouter Saelens
Katleen De Preter
Yvan Saeys
C3
Conference
2016
Unbiased modelling of dynamic processes with single-cell RNA-sequencing
Robrecht Cannoodt
Wouter Saelens
Katleen De Preter
Yvan Saeys
C3
Conference
2016
Unbiased modelling of dynamic processes with single-cell RNA-sequencing
Robrecht Cannoodt
Wouter Saelens
Katleen De Preter
Yvan Saeys
C3
Conference
2016
Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species
Martin Guilliams
Charles-Antoine Dutertre
Charlotte Scott
Naomi McGovern
Dorine Sichien
Svetoslav Chakarov
Sofie Van Gassen
Jinmiao Chen
Michael Poidinger
Sofie De Prijck
et al.
A1
Journal Article
in
IMMUNITY
2016
Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages
Lianne van de Laar
Wouter Saelens
Sofie De Prijck
Liesbet Martens
Charlotte Scott
Gert Van Isterdael
Eik Hoffmann
Rudi Beyaert
Yvan Saeys
Bart Lambrecht
et al.
A1
Journal Article
in
IMMUNITY
2016
2015
An integrated network of Arabidopsis growth regulators and its use for gene prioritization
Ehsan Sabaghian
Zuzanna Drebert
Dirk Inzé
Yvan Saeys
A1
Journal Article
in
SCIENTIFIC REPORTS
2015
Applications of fuzzy rough set theory in machine learning: a survey
Sarah Vluymans
Lynn D'eer
Yvan Saeys
Chris Cornelis
A1
Journal Article
in
FUNDAMENTA INFORMATICAE
2015
Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? : the MeDALL hypothesis
J Bousquet
JM Anto
M Wickman
T Keil
R Valenta
T Haahtela
K Lodrup Carlsen
M van Hage
C Akdis
Claus Bachert
et al.
A1
Journal Article
in
ALLERGY
2015
CATCh, an ensemble classifier for chimera detection in 16S rRNA sequencing studies
Mohamed Mysara
Yvan Saeys
Natalie Leys
Jeroen Raes
Pieter Monsieurs
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2015
Characterization of genome-wide ordered sequence-tagged Mycobacterium mutant libraries by Cartesian Pooling-Coordinate Sequencing
Kristof Vandewalle
Nele Festjens
Evelyn Plets
Marnik Vuylsteke
Yvan Saeys
Nico Callewaert
A1
Journal Article
in
NATURE COMMUNICATIONS
2015
Complex aggregates over clusters of elements
Celine Vens
Sofie Van Gassen
Tom Dhaene
Yvan Saeys
P1
Conference
2015
Computational inference of developmental chronology using flow cytometry data
Leen De Baets
Tom Dhaene
Yvan Saeys
C3
Conference
2015
Differential module analysis in neuroblastoma regulatory networks
Robrecht Cannoodt
Anneleen Beckers
Caroline Van Cauwenbergh
Franki Speleman
Katleen De Preter
Yvan Saeys
C3
Conference
2015
Distributed fuzzy rough prototype selection for big data regression
Sarah Vluymans
Hasan Asfoor
Yvan Saeys
Chris Cornelis
Matthew Tolentino
Ankur Teredesai
Martine De Cock
P1
Conference
2015
Evolutionary undersampling for imbalanced big data classification
Isaac Triguero
Mikel Galar
Sarah Vluymans
Chris Cornelis
Humberto Bustince
Francisco Herrera
Yvan Saeys
P1
Conference
2015
FlowSOM: using self-organizing maps for visualization and interpretation of cytometry data
Sofie Van Gassen
Britt Callebaut
Mary van Helden
Bart Lambrecht
Piet Demeester
Tom Dhaene
Yvan Saeys
A1
Journal Article
in
CYTOMETRY PART A
2015
Fuzzy rough set prototype selection for regression
Sarah Vluymans
Yvan Saeys
Chris Cornelis
Ankur Teredesai
Martine De Cock
P1
Conference
2015
Inferring developmental chronologies from single cell RNA
Robrecht Cannoodt
Wouter Saelens
Katleen De Preter
Yvan Saeys
C3
Conference
2015
Noise analysis in 3D electron microscopy
Joris Roels
Jan Aelterman
Jonas De Vylder
Hiep Luong
Saskia Lippens
Yvan Saeys
Wilfried Philips
C3
Conference
2015
Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster
J Garcia-Aymerich
M Benet
Yvan Saeys
M Pinart
X Basagaña
HA Smit
V Siroux
J Just
I Momas
F Rancière
et al.
A1
Journal Article
in
ALLERGY
2015
Semi-supervised fuzzy-rough feature selection
Richard Jensen
Sarah Vluymans
Neil Mac Parthaláin
Chris Cornelis
Yvan Saeys
P1
Conference
2015
Unsupervised trajectory inference using graph mining
Leen De Baets
Sofie Van Gassen
Tom Dhaene
Yvan Saeys
C1
Conference
2015
2014
Differential module analysis in neuroblastoma regulatory networks
Robrecht Cannoodt
Anneleen Beckers
Caroline Van Cauwenbergh
Katleen De Preter
Yvan Saeys
C3
Conference
2014
Fuzzy rough and evolutionary approaches to instance selection
Nele Verbiest
Chris Cornelis
Yvan Saeys
Dissertation
2014
Identifying novel neuroblastoma oncogenes using semi-supervised learning
Leen De Baets
Robrecht Cannoodt
Joeri Ruyssinck
Katleen De Preter
Tom Dhaene
Yvan Saeys
C3
Conference
2014
Image optimization for 3D electron microscopy images
Joris Roels
Jan Aelterman
Hiep Luong
Jonas De Vylder
Wilfried Philips
Saskia Lippens
Yvan Saeys
C3
Conference
2014
Instance selection for imbalanced data
Sarah Vluymans
Nele Verbiest
Chris Cornelis
Yvan Saeys
C3
Conference
2014
NIMEFI: gene regulatory network inference using multiple ensemble feature importance algorithms
Joeri Ruyssinck
Anh Huynh-Thu Van
Pierre Geurts
Tom Dhaene
Piet Demeester
Yvan Saeys
A1
Journal Article
in
PLOS ONE
2014
Noise analysis and removal in 3D electron microscopy
Joris Roels
Jan Aelterman
Jonas De Vylder
Hiep Luong
Yvan Saeys
Saskia Lippens
Wilfried Philips
P1
Conference
2014
Systematic structural characterization of metabolites in Arabidopsis via candidate substrate-product pair networks
Kris Morreel
Yvan Saeys
Oana Dima
Fachuang Lu
Yves Van de Peer
Ruben Vanholme
John Ralph
Bartel Vanholme
Wout Boerjan
A1
Journal Article
in
PLANT CELL
2014
The function of Fcγ receptors in dendritic cells and macrophages
Martin Guilliams
Pierre Bruhns
Yvan Saeys
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
NATURE REVIEWS IMMUNOLOGY
2014
The image processing revolution: the next step in electron microscopy
Jan Aelterman
Jonas De Vylder
Hiep Luong
Saskia Lippens
Yvan Saeys
Bart Goossens
Wilfried Philips
C3
Conference
2014
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α⁺ dendritic cells
Fabiola Osorio
Simon Tavernier
Eik Hoffmann
Yvan Saeys
Liesbet Martens
Jessica Vetters
Iris Delrue
Riet De Rycke
Eef Parthoens
Philippe Pouliot
et al.
A1
Journal Article
in
NATURE IMMUNOLOGY
2014
2013
A re-ranking algorithm for gene regulatory network predictions using graphlets and graph-invariant properties
Joeri Ruyssinck
Tom Dhaene
Yvan Saeys
C3
Conference
2013
Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach
Pablo Meyer
Geoffrey Siwo
Danny Zeevi
Eilon Sharon
Raquel Norel
Eran Segal
Gustavo Stolovitzky
the DREAM6 consortium
Yvan Saeys
Kathleen Marchal
A1
Journal Article
in
GENOME RESEARCH
2013
Network inference by integrating biclustering and feature selection
Robrecht Cannoodt
Joeri Ruyssinck
Katleen De Preter
Tom Dhaene
Yvan Saeys
C3
Conference
2013
Stable feature selection techniques for microarray data
Sofie Van Gassen
Joeri Ruyssinck
Yvan Saeys
Tom Dhaene
C3
Conference
2013
2012
Flexible motif discovery using feature selection trees: a high performance computing approach
Dries Decap
Bart Dhoedt
Jan Fostier
Yvan Saeys
C3
Conference
2012
Flexible motif discovery using feature selection trees: a high performance computing approach (poster)
Dries Decap
Bart Dhoedt
Jan Fostier
Yvan Saeys
C3
Conference
2012
GenomeView : a next-generation genome browser
Thomas Abeel
Thomas Van Parys
Yvan Saeys
James Galagan
Yves Van de Peer
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2012
Inferring gene regulatory network topologies using ensembles of feature selection techniques
Joeri Ruyssinck
Tom Dhaene
Yvan Saeys
C3
Conference
2012
Inferring gene regulatory networks using ensembles of feature selection techniques
Joeri Ruyssinck
Vân anh Huynh-thu
Pierre Geurts
Tom Dhaene
Piet Demeester
Yvan Saeys
C3
Conference
2012
Playing hide and seek on the genomic playground: unveiling biological function from literature
Sofie Van Landeghem
Yves Van de Peer
Bernard De Baets
Yvan Saeys
Dissertation
2012
SBFC: an efficient feature frequency-based approach to tackle cross-lingual word sense disambiguation
Dieter Mourisse
Els Lefever
Nele Verbiest
Yvan Saeys
Martine De Cock
Chris Cornelis
P1
Conference
2012
Statistical interpretation of machine learning-based feature importance scores for biomarker discovery
Anh Huynh-Thu Van
Yvan Saeys
Louis Wehenkel
Pierre Geurts
A1
Journal Article
in
BIOINFORMATICS
2012
Wisdom of crowds for robust gene network inference
Daniel Marbach
James C Costello
Robert Küffner
Nicole M Vega
Robert J Prill
Diogo M Camacho
Kyle R Allison
Manolis Kellis
James J Collins
Gustavo Stolovitzky
et al.
A1
Journal Article
in
NATURE METHODS
2012
2011
A greedy, graph-based algorithm for the alignment of multiple homologous gene lists
Jan Fostier
Sebastian Proost
Bart Dhoedt
Yvan Saeys
Piet Demeester
Yves Van de Peer
Klaas Vandepoele
A1
Journal Article
in
BIOINFORMATICS
2011
An alternative approach to avoid overfitting for surrogate models
Huu Minh Nguyen
Ivo Couckuyt
Luc Knockaert
Tom Dhaene
Dirk Gorissen
Yvan Saeys
P1
Conference
2011
Avoiding overfitting in surrogate modeling: an alternative approach
Huu Minh Nguyen
Ivo Couckuyt
Yvan Saeys
Luc Knockaert
Tom Dhaene
Dirk Gorissen
C1
Conference
2011
Exploring signature multiplicity in microarray data using ensembles of randomized trees
Pierre Geurts
Yvan Saeys
C1
Conference
2011
High-precision bio-molecular event extraction from text using parallel binary classifiers
Sofie Van Landeghem
Bernard De Baets
Yves Van de Peer
Yvan Saeys
A1
Journal Article
in
COMPUTATIONAL INTELLIGENCE
2011
Peakbin selection in mass spectrometry data using a consensus approach with estimation of distribution algorithms
Rubén Armananzas
Yvan Saeys
Iñaki Inza
Miguel Garcia-Torres
Concha Bielza
Yves Van de Peer
Pedro Larranaga
A1
Journal Article
in
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS
2011
2010
Discriminative and informative features for biomolecular text mining with ensemble feature selection
Sofie Van Landeghem
Thomas Abeel
Yvan Saeys
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2010
Event based text mining for integrated network construction
Yvan Saeys
Sofie Van Landeghem
Yves Van de Peer
C1
Conference
2010
Highlights of the BioTM 2010 workshop on advances in bio text mining
Thomas Abeel
Sofie Van Landeghem
Roser Morante
Vincent Van Asch
Yves Van de Peer
Walter Daelemans
Yvan Saeys
Editorial material
2010
In-silico prediction methods for genome annotation : promoter prediction, biomarker discovery and next-generation sequencing analysis
Thomas Abeel
Yves Van de Peer
Yvan Saeys
Dissertation
2010
Influence of feature selection on ensemble diversity
Huu Minh Nguyen
Luc Knockaert
Tom Dhaene
Piet Demeester
Yvan Saeys
C1
Conference
2010
Robust biomarker identification for cancer diagnosis with ensemble feature selection methods
Thomas Abeel
Thibault Helleputte
Yves Van de Peer
Pierre Dupont
Yvan Saeys
A1
Journal Article
in
BIOINFORMATICS
2010
Towards an ASR-free objective analysis of pathological speech
Catherine Middag
Yvan Saeys
Jean-Pierre Martens
P1
Conference
2010
2009
Analyzing text in search of bio-molecular events: a high-precision machine learning framework
Sofie Van Landeghem
Yvan Saeys
Bernard De Baets
Yves Van de Peer
C1
Conference
2009
Comparison of embedded feature selection algorithms for splice site detection
Huu Minh Nguyen
Yvan Saeys
Luc Knockaert
Tom Dhaene
C3
Conference
2009
Java-ML: a machine learning library
Thomas Abeel
Yves Van de Peer
Yvan Saeys
A1
Journal Article
in
JOURNAL OF MACHINE LEARNING RESEARCH
2009
Toward a gold standard for promoter prediction evaluation
Thomas Abeel
Yves Van de Peer
Yvan Saeys
A1
Journal Article
in
BIOINFORMATICS
2009
Valued constraint satisfaction problems applied to functional harmony
Nele Verbiest
Chris Cornelis
Yvan Saeys
P1
Conference
2009
2008
A review of estimation of distribution algorithms in bioinformatics
Rubén Armañanzas
Iñaki Inza
Roberto Santana
Yvan Saeys
Jose Luis Flores
Jose Antonio Lozano
Yves Van de Peer
Rosa Blanco
Victor Robles
Concha Bielza
et al.
A1
Journal Article
in
BIODATA MINING
2008
Benchmarking machine learning techniques for the extraction of protein-protein interactions from text
Sofie Van Landeghem
Yvan Saeys
Yves Van de Peer
Bernard De Baets
C1
Conference
2008
Comparing distance measures with visual methods
Isis Bonet
Abdel Rodríguez
Ricardo Grau
Maria M García
Yvan Saeys
Ann Nowé
P1
Conference
2008
Extracting protein-protein interactions from text using rich feature vectors and feature selection
Sofie Van Landeghem
Yvan Saeys
Yves Van de Peer
Bernard De Baets
C1
Conference
2008
FunSiP: a modular and extensible classifier for the prediction of functional sites in DNA
Michiel Van Bel
Yvan Saeys
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2008
Generic eukaryotic core promoter prediction using structural features of DNA
Thomas Abeel
Yvan Saeys
Eric Bonnet
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
GENOME RESEARCH
2008
ProSOM: core promoter identification in the human genome
Thomas Abeel
Yvan Saeys
Yves Van de Peer
C1
Conference
2008
ProSOM: core promoter prediction based on unsupervised clustering of DNA physical profiles
Thomas Abeel
Yvan Saeys
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2008
Robust feature selection using ensemble feature selection techniques
Yvan Saeys
Thomas Abeel
Yves Van de Peer
P1
Conference
2008
Towards robust feature selection techniques
Yvan Saeys
Thomas Abeel
Yves Van de Peer
C1
Conference
2008
2007
A review of feature selection techniques in bioinformatics
Yvan Saeys
Iñaki Inza
Pedro Larrañaga
A1
Journal Article
in
BIOINFORMATICS
2007
Enhancing coding potential prediction for short sequences using complementary sequence features and feature selection
Yvan Saeys
Yves Van de Peer
P1
Conference
2007
In search of the small ones: improved prediction of short exons in vertebrates, plants, fungi and protists
Yvan Saeys
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2007
Predicting human immunodeficiency virus (HIV) drug resistance using recurrent neural networks
Isis Bonet
Maria M García
Yvan Saeys
Yves Van de Peer
Ricardo Grau
P1
Conference
2007
Translation initiation site prediction on a genomic scale : beauty in simplicity
Yvan Saeys
Thomas Abeel
Sven Degroeve
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2007
Validating module network learning algorithms using simulated data
Tom Michoel
Steven Maere
Eric Bonnet
Anagha Joshi
Yvan Saeys
Tim Van den Bulcke
Koenraad Van Leemput
Piet Van Remortel
Martin Kuiper
Kathleen Marchal
et al.
A1
Journal Article
in
BMC BIOINFORMATICS
2007
2006
A Scalable Hardware Accelerator for Comparing Protein Sequences
Philippe Faes
Bram Minnaert
M CHRISTIAENS
Eric Bonnet
Yvan Saeys
Dirk Stroobandt
Yves Van de Peer
C1
Conference
2006
Annual Machine Learning Conference of Belgium and The Netherlands
Book editor
2006
Combining signal processing and machine learning techniques for coding potential prediction
Yvan Saeys
Yves Van de Peer
C1
Conference
2006
Enhancing coding potential prediction for short sequences using complementary sequence features and feature selection
Yvan Saeys
Yves Van de Peer
C1
Conference
2006
Feature extraction using clustering of protein
Iris Bonet
Yvan Saeys
Ricardo Grau Ábalo
Maria M García
Robersy Sanchez
Yves Van de Peer
A1
Journal Article
in
Lecture Notes in Computer Science
2006
Feature ranking using an EDA-based wrapper approach
Yvan Saeys
Sven Degroeve
Yves Van de Peer
Bookchapter
in
Towards a new evolutionary computation : advances in estimation of distribution algorithms
2006
Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features
Evelyne Derelle
Conchita Ferraz
Stephane Rombauts
Pierre Rouzé
Alexandra Z Worden
Steven Robbens
Frédéric Partensky
Sven Degroeve
Sophie Echeynié
Richard Cooke
et al.
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2006
Improved core promoter prediction using ensembles of Support Vector Machines
Thomas Abeel
Yvan Saeys
Yves Van de Peer
C1
Conference
2006
Predicting human immunodeficiency virus (HIV) drug resistance using recurrent neural networks
Isis Bonet
Maria M García
Sain Salazar
Robersy Sanchez
Yvan Saeys
Yves Van de Peer
Ricardo Grau
C1
Conference
2006
2005
Genome analysis of the world's smallest free-living eukaryote Ostreococcus tauri unveils unique genome heterogeneity
Steven Robbens
Stephane Rombauts
Pierre Rouzé
Jan Wuyts
Yvan Saeys
Hervé Moreau
Yves Van de Peer
C1
Conference
2005
Large-scale structural analysis of the core promoter in mammalian and plant genomes
Kobe Florquin
Yvan Saeys
Sven Degroeve
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2005
Large-scale structural analysis of the core promoter in mammalian and plant genomes
Kobe Florquin
Yvan Saeys
Sven Degroeve
Yves Van de Peer
C3
Conference
2005
SpliceMachine: predicting splice sites from high-dimensional local context representations
Sven Degroeve
Yvan Saeys
Bernard De Baets
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
BIOINFORMATICS
2005
2004
Building genomic profiles for uncovering segmental homology in the twilight zone
Cedric Simillion
Klaas Vandepoele
Yvan Saeys
Yves Van de Peer
A1
Journal Article
in
GENOME RESEARCH
2004
Building genomic profiles for uncovering segmental homology in the twilight zone
Cedric Simillion
Klaas Vandepoele
Yvan Saeys
Yves Van de Peer
C3
Conference
2004
Digging into acceptor splice site prediction : an iterative feature selection approach
Yvan Saeys
Sven Degroeve
Yves Van de Peer
A1
Journal Article
in
LECTURE NOTES IN ARTIFICIAL INTELLIGENCE
2004
Feature selection for classification of nucleic acid sequences
Yvan Saeys
Yves Van de Peer
Dirk Aeyels
Dissertation
2004
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Pierre Rouzé
Yves Van de Peer
A1
Journal Article
in
BMC BIOINFORMATICS
2004
Selecting relevant features for gene structure prediction
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Pierre Rouzé
Yves Van de Peer
C1
Conference
2004
Splice site prediction in eukaryote genome sequences : the algorithmic issues
Sven Degroeve
Yvan Saeys
Bernard De Baets
Yves Van de Peer
Pierre Rouzé
Bookchapter
in
The new avenues in bioinformatics
2004
The role of non-linear DNA structures in transcription
Kobe Florquin
Sven Degroeve
Yvan Saeys
Yves Van de Peer
C3
Conference
2004
2003
Fast feature selection using a simple estimation of distribution algorithm: a case study on splice site prediction
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Yves Van de Peer
Pierre Rouzé
A1
Journal Article
in
BIOINFORMATICS
2003
Feature selection using a simple estimation of distribution algorithm: a case study on splice site prediction
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Yves Van de Peer
Pierre Rouzé
C3
Conference
2003
Investigating ancient duplication events in the Arabidopsis genome
Jeroen Raes
Klaas Vandepoele
Cedric Simillion
Yvan Saeys
Yves Van de Peer
Bookchapter
in
Genome evolution : gene and genome duplications and the origin of novel gene functions
2003
Investigating ancient duplication events in the Arabidopsis genome
Jeroen Raes
Klaas Vandepoele
Cedric Simillion
Yvan Saeys
Yves Van de Peer
A2
Journal Article
in
JOURNAL OF STRUCTURAL AND FUNCTIONAL GENOMICS
2003
2002
Detecting microcolinearity between Arabidopsis and Rice
Klaas Vandepoele
Yvan Saeys
Cedric Simillion
J RAES
Yves Van de Peer
C1
Conference
2002
Feature subset selection for splice site prediction by estimation of distribution algorithms
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Yves Van de Peer
Pierre Rouzé
C3
Conference
2002
Retrieving DNA sequence information from mass spectra of nucleic acids: application to the detection and identification of SNPs
Yvan Saeys
Dirk Aeyels
Patrick Stanssens
Yves Van de Peer
Marc Zabeau
C3
Conference
2002
Selecting Relevant Features for Splice Site Prediction by Estimation of Distribution Algorithms.
Yvan Saeys
Sven Degroeve
Dirk Aeyels
Yves Van de Peer
Pierre Rouzé
C1
Conference
2002
The automatic detection of homologous regions (ADHoRe) and its application to microcolinearity between Arabidopsis and rice
Klaas Vandepoele
Yvan Saeys
Cedric Simillion
Jeroen Raes
Yves Van de Peer
A1
Journal Article
in
GENOME RESEARCH
2002
2000
A Study and Improvement of the Genetic Algorithm in the CAM-Brain Machine
Yvan Saeys
H VAN MARCK
C1
Conference
2000