Research Explorer

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Researcher

Tessa Kerre

Awards & Distinctions

199 Results

2024

A novel heterozygous variant in AICDA impairs Ig class switching and somatic hypermutation in human B cells and is associated with autosomal dominant HIGM2 syndrome

Erika Della MinaKatherine J. L. JacksonAlexander J. I. CrawfordMegan L. FaulksKarrnan PathmanandavelNicolino AcquarolaMichael O’SullivanTessa KerreLeslie NaesensKarlien Claes et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in acute myeloid leukemia

Niels VandewalleHatice SatilmisEmma VerheyeRong FanYanmeng WangTimo W. M. De GroofJessica BridouxTessa KerreNathan De BeuleAnn De Becker et al.

A1 Journal Article in THERANOSTICS

Baseline chest computed tomography for diagnosis of invasive aspergillosis in patients with acute myeloid leukaemia treated with intensive chemotherapy : a retrospective single‐centre cohort study

Emilie JanssensSammy HuygensIne MoorsAnke DelieTessa KerreYannick Vande WeygaerdeEva Van BraeckelJerina BoelensLieve MorbéeAlexander Schauwvlieghe

A1 Journal Article in MYCOSES

Importance of sinonasal evaluation before transplantation : systematic review with meta-analysis and proposal of a screening protocol

Casper De VrieseConstantijn BogaertSteven Van LaeckeAnke DelieXavier VerhelstTessa KerreThibaut Van Zele

A2 Journal Article in EXPERIMENTAL AND CLINICAL TRANSPLANTATION

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

Stijn De MunterJuliane L. BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukHanne Jansen et al.

A1 Journal Article in CANCER IMMUNOLOGY RESEARCH

Longevity of the humoral and cellular responses after SARS-CoV-2 booster vaccinations in immunocompromised patients

Matthijs OyaertMarie-Angélique De ScheerderSophie Van HerrewegeGuy LaureysSofie Van AsscheMelissa CambronLeslie NaesensLevi HosteKarlien ClaesFilomeen Haerynck et al.

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSASKIA DE SMETNELE LOOTENS et al.

A1 Journal Article in CELL REPORTS MEDICINE

Optimizing computational cytometry tools for clinical applications

Artuur CouckuytYvan SaeysTessa Kerre

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore BillietHanne JansenMelissa PilleLena BöhmeGuillem Sanchez SanchezLaurenz De CockGlenn GoetgelukEva PascalStijn De MunterLucas Deseins et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

2023

Added value of baseline chest CT scan for IPA diagnosis in AML patients receiving intensive chemotherapy : a retrospective single-centre cohort study

Sammy HuygensEmilie JanssensIne MoorsTessa KerreAnke DelieLieve MorbéeAlexander Schauwvlieghe

Agents contributing to secondary immunodeficiency development in patients with multiple myeloma, chronic lymphocytic leukemia and non-Hodgkin lymphoma : a systematic literature review

Stephen JollesSergio GiraltTessa KerreHillard M. LazarusS. Shahzad MustafaRoberto RiaDonald C. Vinh

A1 Journal Article in FRONTIERS IN ONCOLOGY

Cartitude-2 cohort B 18-month follow-up : ciltacabtagene autoleucel (cilta-cel), a BCMA-directed car-T cell therapy, in patients with multiple myeloma (MM) and early relapse after initial therapy

Niels van de DonkMounzer AghaAdam D. CohenYael C. CohenSebastien AnguilleTessa KerreWilfried RoeloffzenDeepu MadduriJordan M. SchecterKevin C. De Braganca et al.

Immunologic monitoring after allogeneic stem cell transplantation : T-SPOT.CMV and QuantiFERON-CMV, are they the same?

Rutger CallensSofie ColmanAnke DelieAlexander SchauwvliegheTom LodewyckDominik SelleslagMarijke ReyndersTessa KerreElizaveta Padalko

A1 Journal Article in TRANSPLANTATION AND CELLULAR THERAPY

Infrared spectroscopy : a new frontier in hematological disease diagnosis

Charlotte DelrueReinhart SpeeckaertMatthijs OyaertTessa KerreSylvie RotteyRenaat CoopmanWouter HuvenneSander De BruyneMarijn Speeckaert

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Innate immune sensors balance infection surveillance and autoinflammation

Leslie NaesensFilomeen HaerynckTessa KerreSimon Tavernier

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion

Stijn De MunterJuliane BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukLore Billiet et al.

Multipotent mesenchymal stromal cells as treatment for poor graft function after allogeneic hematopoietic cell transplantation : a multicenter prospective analysis

Sophie ServaisFrederic BaronChantal LechanteurLaurence SeidelEtienne BaudouxAlexandra BriquetDominik SelleslagJohan MaertensXavier PoireWilfried Schroyens et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Optimization of VHH-based chimeric antigen receptor T cells for the treatment of solid and liquid malignancies

Stijn De MunterBart VandekerckhoveTessa Kerre

Recommendations for management of secondary antibody deficiency in multiple myeloma

Sergio GiraltStephen JollesTessa KerreHillard M. LazarusS. Shahzad MustafaGenovefa A. PapanicolaouRoberto RiaDonald C. VinhJohn R. Wingard

A1 Journal Article in CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Safety and efficacy of autologous stem cell transplantation in dialysis-dependent myeloma patients : the DIADEM study from the chronic malignancies working party of the EBMT

Anna Waszczuk-GajdaLuuk GrasLiesbeth C. de WreedeTiarlan SiraitArpad IllesZubeyde Nur OzkurtJohn A. SnowdenMutlu AratClaude Eric BulaboisJudith Niederland et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Secondary antibody deficiency in chronic lymphocytic leukemia and non-Hodgkin lymphoma : recommendations from an international expert panel

Stephen JollesSergio GiraltTessa KerreHillard M. LazarusS. Shahzad MustafaGenovefa A. PapanicolaouMarcel ReiserRoberto RiaDonald C. VinhJohn R. Wingard

A1 Journal Article in BLOOD REVIEWS

Serious adverse events or reactions in related donors after HPC donation : a report from the EBMT donor outcome registry

Nina WorelAnja de Jonge-HenselerJakob PasswegRegis Peffault de LatourUrs SchanzMutlu AratYves ChalandonAndrew McDonaldChloe AnthiasMohamed Bayoumy et al.

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore BillietLaurenz De CockGuillem Sanchez SanchezRupert MayerGlenn GoetgelukStijn De MunterMelissa PilleJoline IngelsHanne JansenKarin Weening et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia

Rong FanHatice SatilmisNiels VandewalleEmma VerheyeElke De BruyneEline MenuNathan De BeuleAnn De BeckerGamze AtesAnn Massie et al.

A1 Journal Article in BLOOD CANCER JOURNAL

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Melissa PilleJohn AvilaGuillem Sanchez SanchezGlenn GoetgelukStijn De MunterHanne JansenLore BillietKarin WeeningHaipeng XueSarah Bonte et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The phase 2 CARTITUDE-2 trial : updated efficacy and safety of ciltacabtagene autoleucel in patients with multiple myeloma and 1-3 prior lines of therapy (cohort A) and with early relapse after first line treatment (cohort B)

Jens HillengassAdam D. CohenMounzer E. AghaMichel DelforgeTessa KerreWilfried RoeloffzenHermann EinseleHartmut GoldschmidtKatja WeiselMarc S. Raab et al.

2022

A unique phenotype of longitudinal extensive transverse myelitis in autoimmune lymphoproliferative syndrome

Cathérine DekeyserLeslie NaesensFritz OffnerCiel De VriendtAlexander SchauwvliegheTessa KerreGuy Laureys

A1 Journal Article in JOURNAL OF NEUROIMMUNOLOGY

Allogeneic hematopoietic cell transplantation in patients with therapy-related myeloid neoplasm after breast cancer : a study of the Chronic Malignancies Working Party of the EBMT

Mitja NabergojKatya MauffDietrich BeelenArnold GanserNicolaus KrögerFriedrich StölzelJürgen FinkeJakob PasswegJan CornelissenNatalie Schub et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Autoimmune loss of entero-endocrine cells is a hallmark apeced manifestation that results in severe malabsorption but can recover with immune suppressants

Levi HosteLeslie NaesensSara Van AkenBruno LapauwGuy T'SjoenCharlotte VerrokenNicolette MoesRuth De BruyneTessa KerreFilomeen Haerynck

Biological correlative analyses and updated clinical data of ciltacabtagene autoleucel (cilta-cel), a BCMA-directed CAR-T cell therapy, in patients with multiple myeloma (MM) and early relapse after initial therapy : CARTITUDE-2, cohort B

Niels W. C. J. van de DonkMounzer E. AghaAdam D. CohenYael C. CohenSebastien AnguilleTessa KerreWilfried RoeloffzenJordan Mark SchecterKevin C. De BragancaHelen Varsos et al.

CARTITUDE-2 cohort B : efficacy and safety of ciltacabtagene autoleucel, a chimeric antigen receptor T-cell therapy directed against B-cell maturation antigen, in patients with multiple myeloma and early relapse after initial treatment

Niels W. C. J. Van de DonkMichel DelforgeMounzer AghaAdam D. CohenYael C. CohenJens HillengassSebastien AnguilleTessa KerreWilfried RoeloffzenJordan M. Schecter et al.

Ciltacabtagene autoleucel (cilta-cel), a BCMA-directed CAR-T cell therapy, in patients with multiple myeloma (MM) and early relapse after initial therapy : CARTITUDE-2 cohort B 18-month follow-up

Niels W. C. J. Van de DonkMounzer AghaAdam D. CohenYael C. CohenSebastien AnguilleTessa KerreWilfried W. H. RoeloffzenJordan M. SchecterKevin C. De BragancaCarolyn C. Jackson et al.

Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50

Manfred FliegaufMatias KinnunenSara Posadas-CanteraNadezhda Camacho-OrdonezHassan AbolhassaniLaia AlsinaFaranaz AtschekzeiDelfien BogaertSiobhan O. BurnsJoseph A. Church et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients

Matthijs OyaertMarie-Angélique De ScheerderSophie Van HerrewegeGuy LaureysSofie Van AsscheMelissa CambronLeslie NaesensLevi HosteKarlien ClaesFilomeen Haerynck et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Fecal microbiota transplantation in the treatment of acute gastrointestinal graft-versus-host disease : a retrospective survey of the transplant complications working party of EBMT

J. BilinskiG. W. BasakK. HalaburdaD. WuO. GoloshchapovS. MauryA. TanaseG. Van GorkomAnke DelieTessa Kerre et al.

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensSantoshi MuppalaDhiraj AcharyaJosephine NemegeerDelfien BogaertJung-Hyun LeeKatrien StaesVeronique DebackerPieter De BleserMarieke De Bruyne et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Method comparison between T-SPOT.CMV and QuantiFERON-CMV for immunological monitoring after allogeneic stem cell transplantation

Renaat CallensSofie ColmanAnke DelieAlexander SchauwvliegheT. LodewyckD. SelleslagM. ReyndersTessa KerreElizaveta Padalko

Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPATRICK VERLOOBenson OgunjimiDimitri HemelsoetLevi Hoste et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy

Elena CatanzaroEleonora TurriniTessa KerreSimon SioenAns BaeyensAlessandra GuerriniMohamed Lamin Abdi BellauGianni SacchettiGuglielmo PaganettoDmitri Krysko et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Phase 2 CARTITUDE-2 study (cohort B) : updated clinical data and biological correlative analyses of ciltacabtagene autoleucel (cilta-cel), a BCMA-directed CAR-T cell therapy, in patients with multiple myeloma (MM) and early relapse after initial therapy

Mounzer AghaNiels W. C. J. van de DonkAdam D. CohenYael C. CohenSebastien AnguilleTessa KerreWilfried RoeloffzenJordan M. SchecterKevin C. De BragancaHelen Varsos et al.

Sequential administration of low dose 5-azacytidine (AZA) and donor lymphocyte infusion (DLI) for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in relapse after allogeneic stem cell transplantation (SCT) : a prospective study from the Belgian Hematology Society (BHS)

Xavier PoireCarlos GrauxAurelie OryJulie HermanFrederic BaronHelene SchoemansPhilippe LewalleAnn De BeckerDries DeerenZwi Berneman et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Shortcutting the diagnostic odyssey : the multidisciplinary program for undiagnosed rare diseases in adults (UD-PrOZA)

Nika SchuermansDimitri HemelsoetWim TerrynSanne SteyaertRudy Van CosterPaul CouckeWouter SteyaertBert CallewaertElke BogaertPatrick Verloo et al.

A1 Journal Article in ORPHANET JOURNAL OF RARE DISEASES

The Euroflow PID Orientation Tube in the diagnostic workup of primary immunodeficiency : daily practice performance in a tertiary university hospital

Jana NeirinckAnnelies EmmaneelMalicorne BuysseJan PhilippéSofie Van GassenYvan SaeysXavier BossuytStefanie De BuyserMirjam van der BurgMartin Perez-Andres et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The value of baseline chest CT scan for the diagnosis of ipa in patients with AML treated with intensive chemotherapy : a retrospective single-centre cohort study

Els JanssensSammy HuygensIne MoorsTessa KerreAnke DelieLieve MorbéeJerina BoelensAlexander Schauwvlieghe

Upper and/or lower respiratory tract infection caused by human metapneumovirus after allogeneic stem cell transplantation

J. L. PinanaG. TrideloA. XhaardL. WendelJ. MontoroL. VazquezI. HerasP. LjungmanM. MikulskaU. Salmen-Niemi et al.

Value of baseline CT scan for early diagnosis of IPA in AML patients

Emilie JanssensSammy HuygensIne MoorsTessa KerreAnke DelieLieve MorbéeAlexander Schauwvlieghe

2021

A prospective phase I/IIa trial to evaluate the safety and efficacy of GTA002, an off-the-shelf, ex vivo-cultured allogeneic NK cell preparation in patients with acute myeloid leukemia in complete morphological remission who have measurable residual disease

Michael HeuserWalter M. FiedlerTessa KerreJohan MaertensJakob PasswegArjan Van De LoosdrechtAntonia Maria MuellerJean-Henri BourhisKatarzyna NowekJan Spanholtz et al.

A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: the UPSIDE study protocol

Julia SpieringsAnna van RhenenPaco M. W. WelsingAnne C. A. MarijnissenEllen De LangheNicoletta Del PapaDaan DierickxKarina R. GheorgheJoerg HenesRoger Hesselstrand et al.

A1 Journal Article in BMJ OPEN

Allogeneic hematopoietic cell transplantation in patients with therapy-related myeloid neoplasm after breast cancer treatment : a study of The Chronic Malignancies Working Party of The EBMT

Mitja NabergojKatya MauffDietrich BeelenArnold GanserNicolaus KroegerFriedrich StoelzelJuergen FinkeJakob PasswegJan CornelissenNatalie Schub et al.

Autologous stem cell transplantation for post-transplant lymphoproliferative disorders after solid organ transplantation : a retrospective analysis from the Lymphoma Working Party of the EBMT

Toby A. EyreSophie CaillardHerve FinelAriane BoumendilJaimal KothariHeiner ZimmermannRalf Ulrich TrappeVirginie De WildeEleni TholouliEdward Kanfer et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Clinical, genetic and immunological evaluation of the type I interferonopathy Aicardi-Goutieres syndrome caused by mutations in RNU7-1

Leslie NaesensJosephine NemegeerTessa KerreRudi BeyaertSimon TavernierJonathan MaelfaitFilomeen Haerynck

GTF3A mutations in a patient with herpes simplex encephalitis reveals a novel role in viral immunity by transcribing 5S rRNA pseudogenes serving as RIG-I ligands

Leslie NaesensSantoshi MuppalaJung-Hyun LeeJosephine NemegeerDhiraj AcharyaDelfien BogaertMichiel van GentJens StaalKatrien StaesVeronique Debacker et al.

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJudith ClausSimon SchelfhoutJarno De CraemerLaurens De KetelaereDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa Kerre et al.

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

Sarah BonteStijn De MunterLore BillietGlenn GoetgelukJoline IngelsHanne JansenMelissa PilleLaurenz De CockKarin WeeningTom Taghon et al.

A1 Journal Article in ONCOIMMUNOLOGY

Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

Julian ThalhammerGerhard KindleAlexandra NietersStephan RuschMikko R.J. SeppänenAlain FischeBodo GrimbacherDavid EdgarMatthew BucklandNizar Mahlaoui et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Managing viral hepatitis in cancer patients under immune checkpoint inhibitors : should we take the risk?

Stijn De KeukeleireTijl VermassenZahra Mosala NezhadTessa KerreVibeke KruseHans Van VlierbergheKarim VermaelenSylvie Rottey

A1 Journal Article in IMMUNOTHERAPY

Novel mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPATRICK VERLOOBenson OgunjimiDimitri HemelsoetProgram for Undiagnosed Rare Diseases (UD-PrOZA) et al.

Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency

Leslie NaesensJulie SmetSimon TavernierPetra SchelstraeteLevi HosteStijn LambrechtHelene VerhelstJutte van der Werff Ten BoschAlina FersterSophie Blumental et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TCR-based T cell immunotherapy for AML : multidimensional aids in optimizing treatment and patient identification

Sarah BonteTessa KerreBart Vandekerckhove

Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells

Joline IngelsSaskia De SmetKelly HeynsNele LootensJonas SegaertTom TaghonGeorges LeclercqKarim VermaelenEvelyne WillemsEtienne Baudoux et al.

A1 Journal Article in ACTA CLINICA BELGICA

Use of chimerism analysis after allogeneic stem cell transplantation : Belgian guidelines and review of the current literature

Anke DelieAnke VerlindenKarolien BeelDries DeerenDominiek MazureFrederic BaronDimitri BreemsAnn De BeckerCarlos GrauxPhilippe Lewalle et al.

A1 Journal Article in ACTA CLINICA BELGICA

2020

Allogeneic hematopoietic cell transplantation in patients with therapy-related myeloid neoplasm after breast cancer : a study of the chronic malignancies working party of the EBMT

Mitja NabergojKatya MauffDietrich W. BeelenArnold GanserNicolaus KrogerMartin BornhauserSr. Finke, JurgenJakob R. PasswegJan J. CornelissenNatalie Schub et al.

Big children or small adults? Acute myeloid leukaemia (AML) treatment in adolescence and young adulthood

Karolien MaesBarbara De MoerlooseMARIJKE QUAGHEBEURJOHAN DE MUNTERTessa KerreIne Moors

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Big children or small adults? Leukaemia treatment in adolescence and young adulthood

Rutger CallensBarbara De MoerlooseTessa KerreMARIJKE QUAGHEBEURJOHAN DE MUNTERIne Moors

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Chimeric antigen receptor T-cell therapy : design improvements and therapeutic strategies in cancer treatment

Steven Van SchandevylTessa Kerre

A1 Journal Article in ACTA CLINICA BELGICA

Chimeric antigen receptor-T-cell therapy for B-cell hematological malignancies : an update of the pivotal clinical trial data

Gils RoexTom FeysYves BeguinTessa KerreXavier PoirePhilippe LewallePeter VandenbergheDominique BronSebastien Anguille

A1 Journal Article in PHARMACEUTICS

Clinical significance of TARP expression in pediatric acute myeloid leukemia

B. DepreterBarbara De MoerlooseKarl VandepoeleA. UyttebroeckA. Van DammeB. DenysL. DedekenM. -F. DresseJ. Van der Werff Ten BoschM. Hofmans et al.

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeBarbara DenysLaurence DedekenMarie-Françoise DresseJutte Van Der Werff Ten BoschMattias Hofmans et al.

A1 Journal Article in HEMASPHERE

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

Anne-Catherine DolensKaat DurinckMarieke LavaertJoni Van der MeulenImke VelgheJelle De MedtsKarin WeeningJuliette RoelsKatrien De MulderPieter-Jan Volders et al.

A1 Journal Article in EMBO REPORTS

GATA2 deficiency and haematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertGenevieve LaureysLeslie NaesensDominiek MazureMarieke De BruyneAmy P. HsuVictoria Bordon MariaErik WoutersSimon TavernierBart Lambrecht et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients : a report from the EBMT Severe Aplastic Anemia Working Party

Pedro H. PrataDirk-Jan EikemaBoris AfansyevPaul BosmanFrans SmiersJose L. Diez-MartinCelso Arrais-RodriguesYener KocXavier PoireAnne Sirvent et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

How to make an immune system and a foreign host quickly cohabit in peace? The challenge of acute graft-versus-host disease prevention after allogeneic hematopoietic cell transplantation

Benoit VandenhoveLorenzo CantiHelene SchoemansYves BeguinFrederic BaronCarlos GrauxTessa KerreSophie Servais

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage

Lore BillietGlenn GoetgelukSarah BonteStijn De MunterLaurenz De CockMelissa PilleJoline IngelsHanne JansenKarin WeeningFilip Van Nieuwerburgh et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Improved standardization of flow cytometry diagnostic screening of primary immunodeficiency by software-based automated gating

Eleni LinskensAM DiksJana NeirinckM Perez-AndresEmilie De MaertelaereMA BerkowskaTessa KerreMattias HofmansA Orfaovan Dongen JJM et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly

Stijn De MunterAlexander Van ParysLayla BralJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleLore BillietKarin WeeningAnnick Verhee et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Results from the phase I clinical studies evaluating Cyad-01, a first-generation NKG2D CAR T-cell product in relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome patients

David A. SallmanA. Samer Al-HomsiMarco L. DavilaTessa KerreIne MoorsXavier PoireViolaine HavelangePhilippe LewalleDaniel A. PollyeaEunice S. Wang et al.

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

Sarah BonteStijn De MunterGlenn GoetgelukJoline IngelsMelissa PilleLore BillietTom TaghonGeorges LeclercqBart VandekerckhoveTessa Kerre

A1 Journal Article in ONCOIMMUNOLOGY

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara DepreterKarin WeeningKarl VandepoeleMagnus EssandBarbara De MoerlooseMaria ThemeliJacqueline CloosDiana HanekampIne MoorsINGE D'HONT et al.

A1 Journal Article in HAEMATOLOGICA

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie TaveirneSigrid WahlenWouter Van LoockeLaura KiekensEva PersynEls Van AmmelKatrien De MulderJuliette RoelsLaurentijn TillemanMarc Aumercier et al.

A1 Journal Article in BLOOD

Transplantation for congenital sideroblastic anaemia is feasible and offers outcomes comparable to other transfusion dependent anaemias : a joint retrospective study of the paediatric diseases and severe aplastic anaemia working parties (PDWP/SAAWP) of EBMT

Josu de la FuenteDirk-Jan EikemaPaul BosmanRobert F. WynnMiguel DiazPeter J. ShawAmal Al-SeraihyMuhlis Cem ArMohamed Salaheldin MohamedDominique Bron et al.

2019

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia following total body irradiation : the effect of anti-thymocyte globulin on transplant outcome : ALWP of the EBMT study

Arnon NaglerMyriam LabopinRiitta NiittyvuopioJohan MaertensXavier PoireJan CornelissenPeter RemenyiJean Henri BourhisYves BeguinCharles Craddock et al.

Clinical implications of measurable residual disease in AML : review of current evidence

Ine MoorsKarl VandepoeleJan PhilippéDries DeerenDominik SelleslagDimitri BreemsNicole StraetmansTessa KerreBarbara Denys

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Effect of recombinant zoster vaccine on incidence of Herpes zoster after autologous stem cell transplantation : a randomized clinical trial

Adriana BastidasJavier de la SernaMohamed El IdrissiLidia OostvogelsPhilippe QuittetJavier Lopez-JimenezFiliz VuralDavid PohlreichTsila ZuckermanNicolas C Issa et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evaluation 1 year after the launch of the motion comic immuno-T, explaining patients and their caregivers how immunotherapy strategies work

Chiel Gharakhani NiaBarbara CasteelsJonas SegaertBruno BollaertTessa Kerre

GATA2 deficiency and hematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertLeslie NaesensGenevieve LaureysVictoria Bordon MariaErik WoutersSimon TavernierBart LambrechtFilomeen HaerynckTessa Kerre

HIV rebound is predominantly fueled by genetically identical viral expansions from diverse reservoirs

Marie-Angélique De ScheerderBram VranckenSimon DellicourTimothy SchlubEunok LeeWei ShaoSofie RutsaertChris VerhofstedeTessa KerreThomas Malfait et al.

A1 Journal Article in CELL HOST & MICROBE

Immune dysregulation with lymphoproliferation progressing to a rare T-cell non-hodgkin lymphoma

Leslie NaesensHilde DemuynckKristof CokelaereCiel De VriendtDelfien BogaertCarolien BonroyRik SchrijversFilomeen HaerynckTessa Kerre

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJudith ClausSimon SchelfhoutJarno De CraemerLaurens De KetelaereDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa Kerre et al.

Impact of antithymocyte globulin on outcomes of allogeneic hematopoietic cell transplantation with TBI

Arnon NaglerMyriam LabopinBhagirathbhai DholariaRiitta NiittyvuopioJohan MaertensXavier PoireJan CornelissenPeter RemenyiJean Henri BourhisYves Beguin et al.

A1 Journal Article in BLOOD ADVANCES

Implementation of an adult nurse-led stem cell donor search and long term follow-up process Ghent university hospital

JOHAN DE MUNTERMARIJKE QUAGHEBEURSofie De WildeEvi SprangersAmy SenaveANNA VANTILBORGHPhilip VlummensTessa Kerre

Interim results from the phase I DEPLETHINK trial evaluating the infusion of a NKG2D CAR T-cell therapy post a non-myeloablative conditioning in relapse or refractory acute myeloid leukemia and myelodysplastic syndrome patients

A. Samer Al-HomsiEnkhtsetseg PurevPhilippe LewalleMaher Abdul-HayDaniel A. PollyeaAdriano SalaroliThomas LequertierErik Alcantar-OrozcoFabian BorgheseCaroline Lonez et al.

Molecular interactions controlling immune homeostasis in the marginal zone

Matthias VanderkerkenBart LambrechtTessa Kerre

Multipotent mesenchymal stromal cells for poor graft function after allogeneic hematopoietic cell transplantation : a multicenter prospective study

Sophie ServaisFrederic BaronChantal LechanteurEtienne BaudouxAlexandra BriquetDominik SelleslagJohan A. MaertensXavier PoireWilfried SchroyensCarlos Graux et al.

Pitfalls in diagnosing complement factor I deficiencies : from clinical phenotype to laboratory diagnosis

Leslie NaesensJulie SmetSimon TavernierStijn LambrechtTessa KerreJohan Van de WalleLubka RoumeninaPatrick StordeurFilomeen Haerynck

Primary intestinal aspergillosis resulting in acute intestinal volvulus after autologous stem cell transplantation in a patient with relapsed non-Hodgkin lymphoma : report on a rare infectious complication and a review of the literature

Soetkin KennesDirk Van de PutteJo Van DorpeVANESSA VAN HENDETessa KerrePhilip Vlummens

A1 Journal Article in ACTA CLINICA BELGICA

Providing both autologous and allogeneic hematopoietic stem cell transplants (HSCT) may have a stronger impact on the outcome of autologous HSCT in adult patients than activity levels or implementation of JACIE at Belgian transplant centres

Helene A. PoirelMarijke VanspauwenGilles MacqAnke De GeyndtJohan MaertensEvelyne WillemsDominik SelleslagXavier PoireKoen TheunissenCarlos Graux et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Results from the completed dose-escalation of the hematological arm of the Phase I Think Study evaluating multiple infusions of NKG2D-based CAR T-cells as standalone therapy in relapse/refractory acute myeloid leukemia and myelodysplastic syndrome patients

David A. SallmanJason B. BrayerXavier PoireViolaine HavelangeAhmad AwadaPhilippe LewalleKunle OdunsiEunice S. WangCaroline LonezThomas Lequertier et al.

TARP as immunotherapeutic target in AML expressed in the LSC compartment

Barbara DepreterKarin WeeningKarl VandepoeleM EssandBarbara De MoerlooseM ThemeliJ CloosD HanekampIne MoorsINGE D'HONT et al.

2018

A Belgian consensus protocol for autologous hematopoietic stem cell transplantation in multiple sclerosis

Guy LaureysBarbara WillekensLudo VanopdenboschOlivier DeryckDominik SelleslagMiguel D'HaeseleerAnn De BeckerBenedicte DuboisDaan DierickxGaetano Perrotta et al.

A1 Journal Article in ACTA NEUROLOGICA BELGICA

A crépinette sign

Soetkin KennesCiel De VriendtDominiek MazurePieter De VisschereTessa Kerre

A national multi-center randomized study to assess the accuracy, reliability, and user satisfaction of the Ebmt GvHD App in graft versus host disease assessment

Helene M SchoemansKathy GorisRaf Van DurmKoen VanbrabantSabina De GeestSteven Z PavleticAnnie ImDaniel WolffStephanie J LeeHildegard Greinix et al.

Early signs of clinical activity in Aml patients receiving NKG2D CAR T cell therapy in the absence of pre-conditioning chemotherapy : an alternative strategy to CAR T cell therapy

Eytan BremanDavid A SallmanJason B BrayerXavier PoireTessa KerrePhilippe LewalleEunice S WangBikash VermaMarco L DavilaNathalie Braun et al.

Haploidentical transplantation using high dose post-transplant cyclophosphamide for patients with aplastic anemia : the European Group for Blood and Marrow Transplantation experience

Pedro H PrataBoris AfanasyevDirk-Jan EikemaFrans SmiersCora KnolJose L Diez-MartinVanderson G RochaYener KocXavier PoireNathalie Fegueux et al.

Hereditary polycystic kidney disease is characterized by lymphopenia across all stages of kidney dysfunction : an observational study

Steven Van LaeckeTessa KerreEvi NaglerBart MaesRogier CaluweEva SchepersGriet GlorieuxWim Van BiesenFrancis Verbeke

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Immuno-T, a motion comic educating patients and caregivers on how immunotherapy works

Chiel Gharakhani NiaStijn CalisYves BertrandLieve AchtenJASMIEN SOETENSBarbara CasteelsDaisy FlamezBruno BollaertTessa Kerre

Nanobody based dual specific CARs

Stijn De MunterJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleKarin WeeningTessa KerreHinrich AbkenBart Vandekerckhove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phase 1 studies assessing the safety and clinical activity of multiple doses of a NKG2D-based CAR-T therapy, Cyad-01, in acute myeloid leukemia

Jason B BrayerDavid A SallmanTessa KerreXavier PoireViolaine HavelangePhilippe LewalleEunice S WangDominik SelleslagSebastien AnguilleYves Beguin et al.

Remissions in relapse/refractory acute myeloid leukemia patients following treatment with NKG2D CAR-T therapy without a prior preconditioning chemotherapy

David A SallmanTessa KerreXavier PoireViolaine HavelangePhilippe LewalleMarco L DavilaEunice S WangDoreen DekkerSarah SnykersPanagiota A Sotiropoulou et al.

The THINK clinical trial : preliminary evidence of clinical activity of NKG2D chimeric antigen receptor T cell therapy (CYAD-01) in acute myeloid leukemia

David A SallmanJason B BrayerXavier PoireTessa KerrePhilippe LewalleEunice S WangBikash VermaEytan BremanMarco DavilaNathalie Braun et al.

The eGVHD App has the potential to improve the accuracy of graft-versus-host disease assessment : a multicenter randomized controlled trial

Helene M SchoemansKathy GorisRaf Van DurmSteffen FieuwsSabina De GeestSteven Z PavleticAnnie ImDaniel WolffStephanie J LeeHildegard Greinix et al.

A1 Journal Article in HAEMATOLOGICA

2017

A NKG2D-based CAR-T therapy in a multinational phase I dose escalation and expansion study targeting multiple solid and hematologic tumor types

Bikash VermaPhilippe Georges AftimosAhmad AwadaJean -Pascal H MachielsJason B BrayerDavid A SallmanTessa KerreKunle OdunsiCaroline LonezDavid Edward Gilham et al.

A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties

Aline Van AckerKonrad GronkeAindrila BiswasLiesbet MartensYvan SaeysJessica FiltjensSylvie TaveirneEls Van AmmelTessa KerrePatrick Matthys et al.

A1 Journal Article in CELL REPORTS

A phase I global trial targeting multiple solid and hematologic malignancies through a NKG2D receptor-based CAR-T immunotherapy

B VermaA AwadaP AftimosP LewalleN MeulemanJ-P MachielsG CatalaE VandennesteJ BrayerD Sallman et al.

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Yasmine Van CaeneghemStijn De MunterPaola TieppoGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqTessa Kerre et al.

A1 Journal Article in ONCOIMMUNOLOGY

Bijwerkingen van 'immune checkpoint' inhibitoren : waar dient een huisarts alert op te zijn?

S De KeukeleireTessa KerrePiet OstBarbara De MoerlooseKarim VermaelenLieve BrochezVibeke Kruse

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

E-Learning as a tool for continuing education of nurses in hematopoietic stem cell transplantation

Tieneke BautersJOHAN DE MUNTERSophie Van LanckerTessa KerreGenevieve LaureysAnnelies MannaertsLiesbeth SteendamCatharina Dhooge

In vitro generation of tumor antigen-specific T cells from patient and healthy donor stem cells

Sarah BonteSylvia SnauwaertGlenn GoetgelukBart VandekerckhoveTessa Kerre

Medicamenteus geïnduceerde hyponatriëmie : het SIADH-syndroom

Annemie SomersKaren VermisLorenz Van der LindenIsabel SprietTessa KerreMirko Petrovic

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Study protocol for THINK : a multinational open-label phase I study to assess the safety and clinical activity of multiple administrations of NKR-2 in patients with different metastatic tumour types

Caroline LonezBikash VermaAlain HendliszPhilippe AftimosAhmad AwadaEric Van den NesteGaetan CatalaJean-Pascal H MachielsFanny PietteJason B Brayer et al.

A1 Journal Article in BMJ OPEN

The ION-Ghent guidelines for the management of immune related adverse events (irAE's)

Vibeke KruseMax SchreuerKarim VermaelenPiet OstTessa KerreBarbara De MoerlooseLieve Brochez

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

The checkpoint for agonist selection precedes conventional selection in human thymus

Greet VerstichelDavid VermijlenLiesbet MartensGlenn GoetgelukMargreet BrouwerNicolas ThiaultYasmine Van CaeneghemStijn De MunterKarin WeeningSarah Bonte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaBart LambrechtTessa Kerre et al.

A1 Journal Article in HAEMATOLOGICA

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaBart LambrechtTessa Kerre et al.

Thymic development of a new innate CD8+ T cell population

Greet VerstichelBart VandekerckhoveTessa Kerre

2016

CVID, isolated IgG deficiency and isolated IgG subclass deficiency : clinical features and B cell maturation of the Ghent cohort

Delfien BogaertVeronique De BackerTessa KerreVictoria Bordon MariaBart LambrechtKarim VermaelenFrans De BaetsElfride De BaereMelissa DullaersFilomeen Haerynck

Early TCRA rearrangements favor development of agonist selected CD8ααhi T cells in human

Greet VerstichelGlenn GoetgelukLiesbet MartensYvan SaeysTessa KerreHilde CheroutreDavid VermijlenBart Vandekerckhove

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours

Jessica FiltjensJiri KeirsseEls Van AmmelSylvie TaveirneAline Van AckerTessa KerreTom TaghonBart VandekerckhoveJean PlumJo A Van Ginderachter et al.

A1 Journal Article in SCIENTIFIC REPORTS

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

Inge Van de WalleAnne-Catherine DolensKaat DurinckKatrien De MulderWouter Van LoockeSagar DamleEls WaegemansJelle De MedtsImke VelgheMagda De Smedt et al.

A1 Journal Article in NATURE COMMUNICATIONS

Humanized mice to study human T cell development

Sarah BonteSylvia SnauwaertStijn VanheeAnne-Catherine DolensTom TaghonBart VandekerckhoveTessa Kerre

Bookchapter in T-Cell development : methods and protocols

JAK2 deficiency as a novel cause of impaired Th17 immunity

Filomeen HaerynckDelfien BogaertElfride De BaereKristof Van SchilFrauke CoppietersMarieke De BruyneMargot HagendorensTessa KerreFrans De BaetsVictoria Bordon Maria et al.

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection

Jessica FiltjensNicolas ColtelSabrina CencigSylvie TaveirneEls Van AmmelAline Van AckerTessa KerrePatrick MatthysTom TaghonBart Vandekerckhove et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology

Delfien BogaertPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaTessa KerreBart LambrechtAndrea CeruttiKarim Vermaelen et al.

The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression

Aline Van AckerEls LouagieJessica FiltjensSylvie TaveirneEls Van AmmelTessa KerreDirk ElewautTom TaghonBart VandekerckhoveJean Plum et al.

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Yannick WillemenJohan M. J. Van den BerghSarah BonteSebastien AnguilleCarlo HeirmanBarbara MH SteinHerman GoossensTessa KerreKris ThielemansMarc Peeters et al.

A1 Journal Article in ONCOTARGET

Vaccination following stem cell transplantation in adults: initiatives to improve vaccination adherence and follow-up

J De MunterM QuaghebeurT BautersIne MoorsTessa Kerre

2015

Chimeric antigen receptor transgenic, T cell receptor/CD3 negative monospecific T cells generated from cord blood CD34 positive cells

Yasmine Van CaeneghemGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqFritz OffnerHinrich AbkenTessa Kerre et al.

Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSylvia SnauwaertM HeemskerkH StaussR StripeckeB VandekerckhoveTessa Kerre

Immune recovery after allogeneic hematopoietic stem cell transplantation following Flu-TBI versus TLI-ATG conditioning

Muriel HannonYves BeguinGrégory EhxSophie ServaisLaurence SeidelCarlos GrauxJohan MaertensTessa KerreColine DaulneMuriel de Bock et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart Lambrecht et al.

A1 Journal Article in HAEMATOLOGICA

In vitro studies on human hematopoiesis

Stijn VanheeBart VandekerckhoveTessa Kerre

Non-myeloablative allogeneic hematopoietic cell transplantation following fludarabine plus 2 Gy TBI or ATG plus 8 Gy TLI: a phase II randomized study from the Belgian Hematological Society

Frédéric BaronPierre ZachéeJohan MaertensTessa KerreAurélie OryLaurence SeidelCarlos GrauxPhilippe LewalleMichel Van GelderKoen Theunissen et al.

A1 Journal Article in JOURNAL OF HEMATOLOGY & ONCOLOGY

2014

A case of dendritic cell, monocyte, B and NK lymphoid deficiency (DCML)

Melissa DullaersTessa KerreFrauke CoppietersDorine SichienNancy De CabooterVeronique DebackerReinhart SpeeckaertPaul CouckeElias DebaereFilomeen Haerynck et al.

Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development

Jessica FiltjensLander FoquetSylvie TaveirneEls Van AmmelMandy VanheesAline Van AckerTessa KerreTom TaghonBart VandekerckhoveJean Plum et al.

A1 Journal Article in PLOS ONE

Follow-up of vaccination status in adults after allogeneic hematopoietic stem cell transplantation

Tieneke BautersLise DinhJOHAN DE MUNTERMARIJKE QUAGHEBEURDominiek MazureLucien NoensTessa Kerre

Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSylvia SnauwaertG GoetgelukM HeemskerkH StaussBart VandekerckhoveTessa Kerre

In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSylvia SnauwaertGlenn GoetgelukH StaussR StripeckeM HeemskerkYasmine Van CaeneghemGreet VerstichelStijn VanheeBart Vandekerckhove et al.

In vitro generation of AML-specific T cells from human hematopoietic progenitor cells : a step towards curing acute myeloid leukemia?

Sylvia SnauwaertTessa KerreBart Vandekerckhove

In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

Sylvia SnauwaertGreet VerstichelSarah BonteGlenn GoetgelukStijn VanheeYasmine Van CaeneghemKatrien De MulderCarlo HeirmanHans StaussMiriam HM Heemskerk et al.

A1 Journal Article in LEUKEMIA

In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemNadine Van RoyBjörn MentenImke VelgheJan PhilippéTom TaghonGeorges LeclercqTessa Kerre et al.

Ly49E Expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases

Aline Van AckerJessica FiltjensSophie Van WeldenSylvie TaveirneEls Van AmmelMandy VanheesLindsey DevisscherTessa KerreTom TaghonBart Vandekerckhove et al.

A1 Journal Article in PLOS ONE

Notch3 activation is sufficient but not required for inducing human T-lineage specification

Els WaegemansInge Van de WalleJelle De MedtsMagda De SmedtTessa KerreBart VandekerckhoveGeorges LeclercqTao WangJean PlumTom Taghon

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Polyfunctional tumor antigen-specific T cells generated in vitro from human CD34 positive precursor cells transduced to express T cell receptor alpha beta chains fused to CD28-CD3 zeta signaling cassette

Yasmine Van CaeneghemGlenn GoetgelukSylvia SnauwaertFritz OffnerReno DebetsTessa KerreBart Vandekerckhove

Set-up of a long-term follow-up clinic for young adults who had an allogeneic stem cell transplantation during childhood : impact of a good collaboration between pediatric and adult hematological teams

JOHAN DE MUNTERSophie Van LanckerTessa KerreVictoria Bordon MariaCatharina Dhooge

2013

Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function

Jessica FiltjensSylvie TaveirneAline Van AckerEls Van AmmelMandy VanheesTessa KerreTom TaghonBart VandekerckhoveJean PlumGeorges Leclercq

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

CMYB expression during human in vitro hematopoiesis

Stijn VanheeYasmine Van CaeneghemKatrien De MulderImke VelgheSylvie TaveirneNadine Van RoyBjörn MentenSylvia SnauwaertGreet VerstichelMelissa Dullaers et al.

Can immunotherapy specifically target acute myeloid leukemic stem cells?

Sylvia SnauwaertBart VandekerckhoveTessa Kerre

A1 Journal Article in ONCOIMMUNOLOGY

Differential Ly49e expression pathways in resting versus TCR-activated intraepithelial γδ T cells

Tina Van Den BroeckEls Van AmmelMaarten DelforcheSylvie TaveirneTessa KerreBart VandekerckhoveTom TaghonJean PlumGeorges Leclercq

A1 Journal Article in JOURNAL OF IMMUNOLOGY

In vitro generation of antigen-specific T-cells from CD34+haematopoietic progenitor cells: a new and promising immunotherapeutic strategy

Sylvia SnauwaertS Van CoppernolleGreet VerstichelGlenn GoetgelukYasmine Van CaeneghemStijn VanheeImke VelgheJean PlumTessa KerreBart Vandekerckhove

Proctological problems in relation to chemotherapy

Tom LagaertBRUNO VANDUYFHUYSBeatrijs StrubbeINGRID BRUGGEMANKOEN GORLEERPieter HindryckxDaan De MaeseneerIne MoorsStéphanie LaurentKaren Geboes et al.

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

Inge Van de WalleEls WaegemansJelle De MedtsGreet De SmetMagda De SmedtSylvia SnauwaertBart VandekerckhoveTessa KerreGeorges LeclercqJean Plum et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2012

A new case of dendritic cell immunodeficiency: the 'DCML-like' syndrome

Tessa KerreMelissa DullaersDorine SichienReinhart SpeeckaertPaul CouckeB. LambrechtK. Vermaelen

Birdshot-like chorioretinopathy in common variable immunodeficiency

Véronique de MaeyerBart LeroyTessa KerreLiesbeth FerdinandeFilomeen HaerynckFrans De BaetsPhilippe Kestelyn

A2 Journal Article in RETINAL CASES & BRIEF REPORTS

Evaluation of the receptor for hyaluronic acid mediated motility as a tumour-specific antigen in AML

Sylvia SnauwaertStijn VanheeYasmine Van CaeneghemGreet VerstichelGlenn GoetgelukImke VelgheBart VandekerckhoveTessa Kerre

Notch induces T cell receptor gamma delta thymocytes to differentiate along a bipotent CD4 CD8 double positive pathway

Bart VandekerckhoveStefanie Van CoppernolleGreet VerstichelSylvia SnauwaertAnton LangerakTessa Kerre

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertA van der SpekImke VelgheMieke SinnesaelMH HeemskerkTom TaghonGeorges Leclercq et al.

A1 Journal Article in LEUKEMIA

Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength

Tom TaghonInge Van de WalleEls WaegemansJelle De MedtsGreet De SmetMagda De SmedtBart VandekerckhoveTessa KerreGeorges LeclercqTao Wang et al.

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia

Sylvia SnauwaertStijn VanheeGlenn GoetgelukGreet VerstichelYasmine Van CaeneghemImke VelgheJan PhilippéZwi N BernemanJean PlumTom Taghon et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

TCR-dependency of in vitro T cell maturation in OP9-DL1 cocultures

Greet VerstichelSylvia SnauwaertTessa KerreBart Vandekerckhove

The simultaneous appearance of a nasal natural killer-cell lymphoma and acute myelogenous leukemia

L Van CrombruggeG De VosC VancloosterM LemmerlingTessa Kerre

A1 Journal Article in B-ENT

2011

Double positive and double negative TCR gamma delta plus cells independently generate mature functional TCR gamma delta plus cells in the human thymus

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertImke VelgheMieke SinnesaelA van der SpekTom TaghonGeorges LeclercqJean Plum et al.

In vitro generation of immune cells from pluripotent stem cells

Bart VandekerckhoveStijn VanheeStefanie Van CoppernolleSylvia SnauwaertImke VelgheTom TaghonGeorges LeclercqTessa KerreJean Plum

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

Sylvie TaveirneJessica FiltjensEls Van AmmelVeerle De ColvenaerTessa KerreTom TaghonBart VandekerckhoveJean PlumWerner HeldGeorges Leclercq

A1 Journal Article in BLOOD

Outcome in critically ill patients with allogeneic BM or peripheral haematopoietic SCT : a single-centre experience

Pieter DepuydtTessa KerreLucien NoensJOKE NOLLETFritz OffnerJohan DecruyenaereDominique Benoit

A1 Journal Article in BONE MARROW TRANSPLANTATION

Study of human T cell differentiation using the OP9-DL1 co-culture system as a model

Stefanie Van CoppernolleBart VandekerckhoveTessa Kerre

T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells

Magda De SmedtGeorges LeclercqBart VandekerckhoveTessa KerreTom TaghonJean Plum

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

2009

CD4 and CD8 TCR alpha beta cells are selected on MHC expressed on thymocyte precursors in OP9-DL1 cultures

Stefanie Van CoppernolleBart VandekerckhoveGreet VerstichelImke VelgheTom TaghonGeorges LeclercqJean PlumTessa Kerre

Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells

Stefanie Van CoppernolleGreet VerstichelFrank TimmermansImke VelgheDavid VermijlenMagda De SmedtGeorges LeclercqJean PlumTom TaghonBart Vandekerckhove et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Generation of T cells from human embryonic stem cell-derived hematopoietic zones

Frank TimmermansImke VelgheLieve VanwalleghemMagda De SmedtStefanie Van CoppernolleTom TaghonHarry MooreGeorges LeclercqAnton LangerakTessa Kerre et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

2008

Generation of T cells from human embryonic stem cells

Frank TimmermansImke VelgheLieve VanwalleghemMagda De SmedtStefanie Van CoppernolleGeorges LeclercqTom TaghonHarry MooreAnton W LangerakTessa Kerre et al.

Human intrathymic development: a selective approach

Jean PlumMagda De SmedtGeorges LeclercqTom TaghonTessa KerreBart Vandekerckhove

A1 Journal Article in SEMINARS IN IMMUNOPATHOLOGY

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcr alpha beta And Tcr gamma delta T Cells, through Both Conventional and Aberrant Developmental Pathways

Tessa KerreGreet VerstichelStefanie Van CoppernolleImke VelgheFrank TimmermansJean PlumBart Vandekerckhove

2007

A combined case report of 4 adult patients with hemophagocytic lymphohistiocytosis at the Ghent University Hospital in 2006

Tessa KerreE. SteelA. VantilborghFritz OffnerLucien Noens

2002

Active form of notch imposes T cell fate in human progenitor cells

Magda De SmedtKatia ReynvoetTessa KerreTom TaghonBruno VerhasseltBart VandekerckhoveGeorges LeclercqJean Plum

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells.

Tessa KerreG DE SMETM DE SMEDTA ZIPPELIUSMJ PITTETAW LANGERAKJ DE BOSSCHERFritz OffnerBart VandekerckhoveJean Plum

A1 Journal Article in BLOOD

Cytokine deprivation improves the homing of long-term cultured human hematopoietic stem cells after intravenous injection into NOD/SCID mice

Tessa KerreKatrien VanheusdenFritz OffnerJean PlumBart Vandekerckhove

Cytokine deprivation improves the homing of long-term cultured human hematopoietic stem cells after transplantation int NOD/SCID mice

Tessa KerreBart VandekerckhoveFritz OffnerJean Plum

Long term culture of human hematopoietic stem cells influence on homing, organ selectivity, survival and proliferation early after transplantation into NOD/SCID mice

Tessa KerreBart VandekerckhoveFritz OffnerJean Plum

2001

An adapted NOD/SCID model supports the development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells

Tessa KerreBart VandekerckhoveFritz OffnerJean Plum

Both CD34(+)38(+) and CD34(+)38(-) cells home specifically to the bone marrow of NOD/LtSZ scid/scid mice but show different kinetics in expansion.

Tessa KerreG DE SMETM DE SMEDTFritz OffnerJ DE BOSSCHERJean PlumBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

The behavior of long-term cultured human hematopoietic stem cells early after transplantation into NOD/SCID mice provides explanations for their impaired long-term engraftment in this model

Tessa KerreBart VandekerckhoveFritz OffnerJean Plum

2000

Both human CD34(+)38(+) and CD34(+)38(-) cells home specifically to the bone marrow, but show different kinetics in take and proliferation

Tessa KerreG DE SMETMagda De SmedtFritz OffnerJean PlumBart Vandekerckhove

Human T lymphopoiesis - In vitro and in vivo study models.

Jean PlumM DE SMEDTBruno VerhasseltTessa KerreDominique VanheckeBart VandekerckhoveGeorges Leclercq

A1 Journal Article in NEUROIMMUNOMODULATION

Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development.

M DE SMEDTBruno VerhasseltTessa KerreDominique VanheckeE NAESSENSGeorges LeclercqJC RENAULDJ VAN SNICKJean Plum

A1 Journal Article in JOURNAL OF IMMUNOLOGY

1999

Bone marrow CD34+ cells generate fewer T cells in vitro with increasing age and following chemotherapy

Fritz OffnerTessa KerreMagda De SmedtJean Plum

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Gallstone recurrence after successful shock wave therapy: the magnitude of the problem and the predictive factors

Ercan CesmeliAE ElewautTessa KerreMarc De BuyzereMarcel AfschriftAndré Elewaut

A1 Journal Article in AMERICAN JOURNAL OF GASTROENTEROLOGY

Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells

Bruno VerhasseltEvelien NaessensChris VerhofstedeMagda De SmedtSigrid SchollenTessa KerreDominique VanheckeJean Plum

A1 Journal Article in BLOOD

In vitro intrathymic differentiation kinetics of human fetal liver CD34(+)CD38(-) progenitors reveals a phenotypically defined dendritic/T-NK precursor split

Jean PlumMagda De SmedtBruno VerhasseltFritz OffnerTessa KerreD VANHECKEGeorges LeclercqBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Thymic repopulation by CD34+ human cord blood cells after expansion in stroma-free culture

Bruno VerhasseltTessa KerreEvelien NaessensDominique VanheckeMagda De SmedtBart VandekerckhoveJean Plum

A1 Journal Article in BLOOD

1997

Gallstone recurrence after successful shock-wave therapy: the magnitude of the problem and the predictive factors

Ercan CesmeliAE ElewautTessa KerreMarc De BuyzereMarcel AfschriftAndré Elewaut