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Onderzoeker
Steve Lefever
Profiel
Projecten
Publicaties
Activiteiten
Prijzen & Erkenningen
104
Resultaten
2023
Challenges in neoantigen-directed therapeutics
Lien Lybaert
Steve Lefever
Bruno Fant
Evelien Smits
Bruno De Geest
Karine Breckpot
Luc Dirix
Steven A. Feldman
Wim Van Criekinge
Kris Thielemans
et al.
A1
Artikel in een tijdschrift
in
CANCER CELL
2023
Identification and characterization of a novel retinaspecific lncRNA upstream ABCA4 with a potential role in ABCA4-associated inherited retinal disease
Alfredo Dueñas Rey
Victor Lopez Soriano
Zelia Corradi
Claire-Marie Dhaenens
Manon Bouckaert
Jasper Verwilt
Avril Watson
Majlinda Lako
Eva D'haene
Karla Alejandra Ruiz Ceja
et al.
C3
Conferentie
2023
2022
Comprehensive RNA dataset of tissue and plasma from patients with esophageal cancer or precursor lesions
Kathleen Schoofs
Annouck Philippron
Francisco Avila Cobos
Jan Koster
Steve Lefever
Jasper Anckaert
Danny De Looze
Jo Vandesompele
Piet Pattyn
Katleen De Preter
A1
Artikel in een tijdschrift
in
SCIENTIFIC DATA
2022
The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells
Louis Delhaye
Eric de Bony de Lavergne
Dries Rombaut
Lim Fang Qi
Bieke Decaesteker
Lisa Depestel
Amber Louwagie
Eva D'haene
Pieter-Jan Volders
Nurten Yigit
et al.
C3
Conferentie
2022
mRNA capture sequencing and RT-qPCR for the detection of pathognomonic, novel, and secondary fusion transcripts in FFPE tissue : a sarcoma showcase
Anneleen Decock
David Creytens
Steve Lefever
Joni Van der Meulen
Jasper Anckaert
Ariane De Ganck
Jill Deleu
Bram De Wilde
Carolina Fierro
Scott Kuersten
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
2021
Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Liselot Mus
Stéphane Van Haver
Mina Popovic
Wim Trypsteen
Steve Lefever
Nadja Zeltner
Yudelca Ogando
Eva Jacobs
Geertrui Denecker
Ellen Sanders
et al.
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2021
Selection and validation of reference genes for accurate RT-qPCR gene expression normalization in cacao beans during fermentation
Jocelyn De Wever
Tibo De Coninck
Helena Everaert
Emmanuel Ohene Afoakwa
Frauke Coppieters
Hayley Rottiers
Stephen Yaw Opoku
Samuel Lowor
Koen Dewettinck
Jo Vandesompele
et al.
A1
Artikel in een tijdschrift
in
TREE GENETICS & GENOMES
2021
The RNA Atlas expands the catalog of human non-coding RNAs
Lucia Lorenzi
Hua-Sheng Chiu
Francisco Avila Cobos
Stephen Gross
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
et al.
A1
Artikel in een tijdschrift
in
NATURE BIOTECHNOLOGY
2021
The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)
Lucia Lorenzi
Hua-Sheng Chiu
Francisco Avila Cobos
Stephen Gross
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
et al.
Correctie
2021
Validation of circular RNAs using RT‐qPCR after effective removal of linear RNAs by ribonuclease R
Marieke Vromman
Nurten Yigit
Kimberly Verniers
Steve Lefever
Jo Vandesompele
Pieter-Jan Volders
A2
Artikel in een tijdschrift
in
CURRENT PROTOCOLS
2021
2020
A combined RNA preservation and extraction protocol for gene expression studies in cacao beans
Jocelyn De Wever
Dieter Tulkens
Jan Verwaeren
Helena Everaert
Hayley Rottiers
Koen Dewettinck
Steve Lefever
Kathy Messens
A1
Artikel in een tijdschrift
in
FRONTIERS IN PLANT SCIENCE
2020
Charting extracellular transcriptomes in the human biofluid RNA atlas
Eva Hulstaert
Annelien Morlion
Francisco Avila Cobos
Kimberly Verniers
Justine Nuytens
Eveline Vanden Eynde
Nurten Yigit
Jasper Anckaert
Anja Geerts
Pieter Hindryckx
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS
2020
Genetic classification of Vietnamese cacao cultivars assessed by SNP and SSR markers
Helena Everaert
Jocelyn De Wever
Thi Kim Hong Tang
Thi Lam An Vu
Kevin Maebe
Hayley Rottiers
Steve Lefever
Guy Smagghe
Koen Dewettinck
Kathy Messens
A1
Artikel in een tijdschrift
in
TREE GENETICS & GENOMES
2020
Genotyping and bean transcriptomics towards identification of cacao flavor genes
Jocelyn De Wever
Kathy Messens
Steve Lefever
Proefschrift
2020
Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity
Iuliia Efimova
Elena Catanzaro
Louis Van der Meeren
Victoria Turubanova
Hamida Hammad
Tatiana Mishchenko
Maria Vedunova
Carmela Fimognari
Claus Bachert
Frauke Coppieters
et al.
A1
Artikel in een tijdschrift
in
JOURNAL FOR IMMUNOTHERAPY OF CANCER
2020
2019
Antisense oligonucleotide-based downregulation of the G56R pathogenic variant causing NR2E3-associated autosomal dominant retinitis pigmentosa
Sarah Naessens
Laurien Ruysschaert
Steve Lefever
Frauke Coppieters
Elfride De Baere
A1
Artikel in een tijdschrift
in
GENES
2019
Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR
Steve Lefever
Ali Rihani
Joni Van der Meulen
Filip Pattyn
Tom Van Maerken
Jo Van Dorpe
Jan Hellemans
Jo Vandesompele
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2019
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes
Dries Rombaut
Hua-Sheng Chiu
Bieke Decaesteker
Celine Everaert
Nurten Yigit
Agathe Pelthier
Isabelle Janoueix
Christophe Bartenhagen
Matthias Fischer
Stephen Roberts
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2019
LncRNAs as novel players in neuroblastoma tumor biology
Dries Rombaut
Pieter Mestdagh
Steve Lefever
Proefschrift
2019
Long non-coding RNAs and latent HIV : a search for novel targets for latency reversal
Wim Trypsteen
Cory H White
Amey Mukim
Celsa A Spina
Ward De Spiegelaere
Steve Lefever
Christopher H Woelk
Alberto Bosque
Linos Vandekerckhove
Nadejda Beliakova-Bethell
C3
Conferentie
2019
Long noncoding RNA expression profiling in cancer : challenges and opportunities
Lucia Lorenzi
Francisco Avila Cobos
Anneleen Decock
Celine Everaert
Hetty Helsmoortel
Steve Lefever
Karen Verboom
Pieter-Jan Volders
Franki Speleman
Jo Vandesompele
et al.
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2019
PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow
Frauke Coppieters
Thalia Van Laethem
Matthias De Smet
Paul Coucke
Elfride De Baere
Kathleen Claes
Björn Menten
Jo Vandesompele
Steve Lefever
C3
Conferentie
2019
The RNA Atlas, a single nucleotide resolution map of the human transcriptome
Lucia Lorenzi
Hua-Sheng Chiu
Francisco Avila Cobos
Stephen Gross
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
et al.
Preprint
2019
The development of a novel SNP genotyping assay to differentiate cacao clones
Jocelyn De Wever
Helena Everaert
Frauke Coppieters
Hayley Rottiers
Koen Dewettinck
Steve Lefever
Kathy Messens
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2019
Variant calling and fusion gene detection in formalin-fixed paraffin-embedded tumor tissue using RNA capture sequencing
Anneleen Decock
David Creytens
Joni Van der Meulen
Sandra Steyaert
Carolina Fierro
Manuel Luypaert
Steve Lefever
Eveline Vanden Eynde
Katrien Vanderheyden
Kimberly Verniers
et al.
C3
Conferentie
2019
2018
A comprehensive pan-cancer molecular study of gynecologic and breast cancers
Ashton C Berger
Anil Korkut
Rupa S Kanchi
Apurva M Hegde
Walter Lenoir
Wenbin Liu
Yuexin Liu
Huihui Fan
Hui Shen
Visweswaran Ravikumar
et al.
A1
Artikel in een tijdschrift
in
CANCER CELL
2018
A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes
Gert Van Peer
Evelien Mets
Shana Claeys
Ines De Punt
Steve Lefever
Maté Ongenaert
Pieter Rondou
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
A1
Artikel in een tijdschrift
in
PLOS ONE
2018
A mechanistic classification of clinical phenotypes in neuroblastoma.
Sandra Ackermann
Maria Cartolano
Barbara Hero
Anne Welte
Yvonne Kahlert
Andrea Roderwieser
Christoph Bartenhagen
Esther Walter
Judith Gecht
Laura Kerschke
et al.
A1
Artikel in een tijdschrift
in
SCIENCE
2018
Contribution of lncRNAs in establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Pieter Mestdagh
Steve Lefever
Celsa A Spina
Linos Vandekerckhove
Nadejd Beliakova-Bethell
C3
Conferentie
2018
Contribution of lncRNAs in the establishment of HIV latency in CD4+ T cell models
Wim Trypsteen
Clarissa Van Hecke
Tinus Schynkel
Cory H White
Christopher Woelk
Alberto Bosque
Celsa Spina
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
et al.
C3
Conferentie
2018
How long noncoding RNAs enforce their will on mitochondrial activity : regulation of mitochondrial respiration, reactive oxygen species production, apoptosis, and metabolic reprogramming in cancer
Boel De Paepe
Steve Lefever
Pieter Mestdagh
A1
Artikel in een tijdschrift
in
CURRENT GENETICS
2018
Targeted genomic screen reveals focal long non-coding RNA copy number alterations in cancer cell lines
Pieter-Jan Volders
Steve Lefever
Shalina Baute
Justine Nuytens
Katrien Vanderheyden
Björn Menten
Pieter Mestdagh
Jo Vandesompele
A2
Artikel in een tijdschrift
in
NON-CODING RNA
2018
The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease
Bram De Wilde
Anneleen Beckers
Sven Lindner
Kristina Althoff
Katleen De Preter
Pauline Depuydt
Pieter Mestdagh
Tom Sante
Steve Lefever
Falk Hertwig
et al.
A2
Artikel in een tijdschrift
in
ONCOTARGET
2018
The neuroblastoma-specific lncRNA NESPR activates PHOX2B expression and is essential for neuroblastoma cell survival
Dries Rombaut
Tiago França Brazao
Louis Delhaye
Eva D'haene
Giorgio Milazzo
Roberto Ciaccio
Nurten Yigit
Celine Everaert
Matthias Fischer
Thorsten Simon
et al.
C3
Conferentie
2018
Two cases of seborrheic keratosis of the external ear canal : involvement of PIK3CA and FGFR3 genes
MARIE DE LOOF
Jo Van Dorpe
Joni Van der Meulen
Steve Lefever
Ingeborg Dhooge
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF DERMATOLOGY
2018
2017
A next-generation sequencing approach targeting the highly repetitive ORF15 region of RPGR improves molecular diagnostics of X-linked retinitis pigmentosa
Annelies De Jaegher
Sarah De Jaegere
Toon Rosseel
Steve Lefever
Frauke Coppieters
Kim De Leeneer
Elfride De Baere
C3
Conferentie
2017
Contribution of lncRNAs in establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Celsa Spina
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
Nadejd Beliakova-Bethell
C3
Conferentie
2017
Contribution of lncRNAs in the establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
Christopher Woelk
C3
Conferentie
2017
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay (vol 6, 36111, 2016)
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
Correctie
2017
High-throughput PCR assay design for targeted resequencing using primerXL
Steve Lefever
Filip Pattyn
Bram De Wilde
Frauke Coppieters
Sarah De Keulenaer
Jan Hellemans
Jo Vandesompele
A1
Artikel in een tijdschrift
in
BMC BIOINFORMATICS
2017
In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations
Joni Van der Meulen
Barbara Denys
Elien De Latter
Steve Lefever
Toon Rosseel
Wouter Steyaert
GRETA VAN DER CRUYSSEN
Isabelle Rottiers
David Creytens
Jo Van Dorpe
et al.
C3
Conferentie
2017
In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations
Joni Van der Meulen
Barbara Denys
Elien De Latter
Steve Lefever
Toon Rosseel
Wouter Steyaert
GRETA VAN DER CRUYSSEN
Isabelle Rottiers
David Creytens
Jo Van Dorpe
et al.
C3
Conferentie
2017
Molecular characterization of Theobroma cacao L. clones from Vietnam
Helena Everaert
Hayley Rottiers
Jocelyn De Wever
Steve Lefever
Frauke Coppieters
Pham Hong Duc Phuoc
Ha Lam Thi Viet
Thi Phuong Dung Nguyen
Diem Phuong Tran
Koen Dewettinck
et al.
C3
Conferentie
2017
Second hit landscape in BRCA-associated breast cancer
Mattias Van Heetvelde
Mieke Van Bockstal
Trees Lepez
Steve Lefever
Leen Pieters
Kathleen Lambein
Marleen Praet
Ivo Van Den Berghe
Frauke Coppieters
Nadine Van Roy
et al.
C3
Conferentie
2017
decodeRNA-predicting non-coding RNA functions using guilt-by-association
Steve Lefever
Jasper Anckaert
Pieter-Jan Volders
Manuel Luypaert
Jo Vandesompele
Pieter Mestdagh
A1
Artikel in een tijdschrift
in
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
2017
lncRNA discovery in the HIV replication cycle adds new layer in HIV-host interplay
Wim Trypsteen
Mohammadi Pejman
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Ward De Spiegelaere
Linos Vandekerckhove
C3
Conferentie
2017
2016
Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR
Pieter Mestdagh
Steve Lefever
Pieter-Jan Volders
Stefaan Derveaux
Jan Hellemans
Jo Vandesompele
A1
Artikel in een tijdschrift
in
SCIENTIFIC DATA
2016
Long non-coding RNAs as novel components in the TP53 pathway
Dries Rombaut
Steve Lefever
Jan Koster
Johannes Schulte
Rogier Versteeg
Peter van Sluis
Jo Vandesompele
Pieter Mestdagh
C3
Conferentie
2016
Long non-coding RNAs as novel components in the TP53 pathway
Dries Rombaut
Steve Lefever
Jan Koster
Sven Lindner
Johannes Schulte
Rogier Versteeg
Peter van Sluis
Jo Vandesompele
Pieter Mestdagh
C3
Conferentie
2016
RT-qPCR gene expression analysis in zebrafish : preanalytical precautions and use of expressed repetitive elements for normalization
Suzanne Vanhauwaert
Steve Lefever
Paul Coucke
Franki Speleman
Anne De Paepe
Jo Vandesompele
Andy Willaert
A1
Artikel in een tijdschrift
in
Methods in Cell Biology
2016
Targeted resequencing and variant validation using pxlence PCR assays
Frauke Coppieters
Kimberly Verniers
Kim De Leeneer
Jo Vandesompele
Steve Lefever
A2
Artikel in een tijdschrift
in
BIOMOLECULAR DETECTION AND QUANTIFICATION
2016
Thorough second hit analysis in BRCA1/2 associated breast cancer
Mattias Van Heetvelde
Trees Lepez
Leen Pieters
Steve Lefever
Jo Van Dorpe
Kathleen Lambein
Marleen Praet
ivo Van Den Berghe
Frauke Coppieters
Jo Vandesompele
et al.
C3
Conferentie
2016
Thorough second-hit analysis in BRCA1/2-associated breast cancer
Mattias Van Heetvelde
Trees Lepez
Leen Pieters
Steve Lefever
Jo Van Dorpe
Kathleen Lambein
Marleen Praet
Ivo Van Den Berghe
Frauke Coppieters
Jo Vandesompele
et al.
C3
Conferentie
2016
2015
Best-in-class PCR based target enrichment for NGS panels and Sanger variant confirmation
Steve Lefever
Frauke Coppieters
Jo Vandesompele
C3
Conferentie
2015
Flexible, scalable, and efficient targeted resequencing on a benchtop sequencer for variant detection in clinical practice
Kim De Leeneer
Jan Hellemans
Wouter Steyaert
Steve Lefever
Inge Vereecke
Eveline Debals
Brecht Crombez
Machteld Baetens
Mattias Van Heetvelde
Frauke Coppieters
et al.
A1
Artikel in een tijdschrift
in
HUMAN MUTATION
2015
Long non-coding RNAs as upstream regulators and downstream effectors of TP53 activity in neuroblastoma
Dries Rombaut
Steve Lefever
Jan Koster
Johannes Schulte
Rogier Versteeg
Peter van Sluis
Jo Vandesompele
Pieter Mestdagh
C3
Conferentie
2015
RDML-Ninja and RDMLdb for standardized exchange of qPCR data
Jan M Ruijter
Steve Lefever
Jasper Anckaert
Jan Hellemans
Michael W Pfaffl
Vladimir Benes
Stephen A Bustin
Jo Vandesompele
Andreas Untergasser
A1
Artikel in een tijdschrift
in
BMC BIOINFORMATICS
2015
lncRNAs as upstream regulators and downstream effectors of TP53 in neuroblastoma
Dries Rombaut
Steve Lefever
Pieter-Jan Volders
Jan Koster
Sven Lindner
Johannes Schulte
Alan Van Goethem
Rogier Versteeg
Peter van Sluis
Jo Vandesompele
et al.
C3
Conferentie
2015
2014
Copy number analysis of ABCA4 in Belgian patients with Stargardt reveals exon 20-22 deletion
Miriam Bauwens
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Filip Pattyn
Lies Hoefsloot
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2014
Copy number analysis of ABCA4 in Belgian patients with Stargardt reveals exon 20-22 deletion
Miriam Bauwens
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Filip Pattyn
Lies Hoefsloot
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2014
Expressed repeat elements improve RT-qPCR normalization across a wide range of zebrafish gene expression studies
Suzanne Vanhauwaert
Gert Van Peer
Ali Rihani
Els Janssens
Pieter Rondou
Steve Lefever
Anne De Paepe
Paul Coucke
Franki Speleman
Jo Vandesompele
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2014
Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma
Eveline Barbieri
Katleen De Preter
Mario Capasso
Zaowen Chen
Danielle M Hsu
Gian Paolo Tonini
Steve Lefever
John Hicks
Rogier Versteeg
Andrea Pession
et al.
A1
Artikel in een tijdschrift
in
CANCER RESEARCH
2014
Identity-by-descent-guided mutation analysis and exome sequencing in consanguineous families reveals unusual clinical and molecular findings in retinal dystrophy
Frauke Coppieters
Kristof Van Schil
Miriam Bauwens
Hannah Verdin
Annelies De Jaegher
Delfien Syx
Tom Sante
Steve Lefever
Nouha Bouayed Abdelmoula
Fanny Depasse
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2014
Target enrichment using parallel nanoliter quantitative PCR amplification
Bram De Wilde
Steve Lefever
Wes Dong
Jude Dunne
Syed Husain
Stefaan Derveaux
Jan Hellemans
Jo Vandesompele
A1
Artikel in een tijdschrift
in
BMC GENOMICS
2014
miRBase Tracker : keeping track of microRNA annotation changes
Gert Van Peer
Steve Lefever
Jasper Anckaert
Anneleen Beckers
Ali Rihani
Alan Van Goethem
Pieter-Jan Volders
Fjoralba Zeka
Maté Ongenaert
Pieter Mestdagh
et al.
A1
Artikel in een tijdschrift
in
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
2014
2013
A dual approach for comprehensive genetic testing of ABCA4 in Stargardt disease
Miriam Bauwens
Caroline Van Cauwenbergh
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2013
A dual approach for comprehensive genetic testing of ABCA4 in Stargardt disease
Miriam Bauwens
Caroline Van Cauwenbergh
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Filip Pattyn
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2013
A dual approach for comprehensive genetic testing of ABCA4 in Stargardt disease
Miriam Bauwens
Caroline Van Cauwenbergh
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Filip Pattyn
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2013
A dual approach for comprehensive genetic testing of ABCA4 in Stargardt disease
Miriam Bauwens
Caroline Van Cauwenbergh
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2013
Copy number analysis of ABCA4 in Belgian patients with Stargardt reveals exon 20-22 deletion
Miriam Bauwens
Sarah De Jaegere
Steve Lefever
Barbara D'haene
Filip Pattyn
Lies Hoefsloot
Thomy de Ravel de l'Argentière
Bart Leroy
Elfride De Baere
Frauke Coppieters
C3
Conferentie
2013
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes
Candy Kumps
Annelies Fieuw
Pieter Mestdagh
Björn Menten
Steve Lefever
Filip Pattyn
Sara De Brouwer
Tom Sante
Johannes Hubertus Schulte
Alexander Schramm
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2013
High-throughput lncRNA expression profiling identifies candidate cancer lncRNAs
Pieter Mestdagh
Steve Lefever
Kristina Althoff
Carina Leonelli
Jan Hellemans
Jean-Christophe Marine
Johannes Schulte
Jo Vandesompele
C3
Conferentie
2013
Identification and functional characterization of lncRNAs in cancer
Pieter Mestdagh
Steve Lefever
Kristina Althoff
Carina Leonelli
Jan Hellemans
Jean-Christophe Marine
Johannes Schulte
Jo Vandesompele
C3
Conferentie
2013
Identity-by-descent mapping and exome sequencing reveals a new candidate gene for the primary congenital glaucoma locus GLC3E
Hannah Verdin
Bart Leroy
Barbara D'haene
Elise Vantroys
Steve Lefever
Frauke Coppieters
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2013
Identity-by-descent mapping and exome sequencing reveals a new candidate gene for the primary congenital glaucoma locus GLC3E
Hannah Verdin
Bart Leroy
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2013
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
JH Schulte
S Lindner
A Bohrer
J Maurer
Katleen De Preter
Steve Lefever
L Heukamp
S Schulte
J Molenaar
R Versteeg
et al.
A1
Artikel in een tijdschrift
in
ONCOGENE
2013
Regulatory microRNA network identification in bovine blastocyst development
Karen Goossens
Pieter Mestdagh
Steve Lefever
Mario Van Poucke
Alex Van Zeveren
Ann Van Soom
Jo Vandesompele
Luc Peelman
A1
Artikel in een tijdschrift
in
STEM CELLS AND DEVELOPMENT
2013
Single-nucleotide polymorphisms and other mismatches reduce performance of quantitative PCR assays
Steve Lefever
Filip Pattyn
Jan Hellemans
Jo Vandesompele
A1
Artikel in een tijdschrift
in
CLINICAL CHEMISTRY
2013
2012
Development of bioinformatics tools for high-throughput PCR applications
Steve Lefever
Jo Vandesompele
Proefschrift
2012
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Bart Leroy
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2012
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Bart Leroy
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2012
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Bart Leroy
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2012
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Bart Leroy
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Elfride De Baere
C3
Conferentie
2012
Massively parallel sequencing for early molecular diagnosis in Leber congenital amaurosis
Frauke Coppieters
Bram De Wilde
Steve Lefever
Ellen De Meester
Nina De Rocker
Caroline Van Cauwenbergh
Filip Pattyn
Françoise Meire
Bart Leroy
Jan Hellemans
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2012
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform
Sarah De Keulenaer
Jan Hellemans
Steve Lefever
Jean-Pierre Renard
Joachim De Schrijver
Hendrik Van de Voorde
Mohammad Amin Tabatabaiefar
Filip Van Nieuwerburgh
Daisy Flamez
Filip Pattyn
et al.
A1
Artikel in een tijdschrift
in
BMC MEDICAL GENOMICS
2012
2011
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Bart Leroy
Elfride De Baere
C3
Conferentie
2011
Identity-by-descent mapping reveals a new locus for primary congenital glaucoma, GLC3E, on chromosome 19p13.2
Hannah Verdin
Barbara D'haene
Frauke Coppieters
Steve Lefever
Philippe Kestelyn
Bart Leroy
Elfride De Baere
C3
Conferentie
2011
Measurable impact of RNA quality on gene expression results from quantitative PCR
Joëlle Vermeulen
Katleen De Preter
Steve Lefever
Justine Nuytens
Fanny De Vloed
Stefaan Derveaux
Jan Hellemans
Franki Speleman
Jo Vandesompele
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2011
Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics
Kim De Leeneer
Joachim De Schrijver
Lieven Clement
Machteld Baetens
Steve Lefever
Sarah De Keulenaer
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
Sofie Bekaert
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2011
The microRNA body map : dissecting microRNA function through integrative genomics
Pieter Mestdagh
Steve Lefever
Filip Pattyn
Dana Ridzon
Erik Fredlund
Annelies Fieuw
Maté Ongenaert
Joëlle Vermeulen
Anne De Paepe
Linda Wong
et al.
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2011
2010
Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline
Joachim De Schrijver
Kim De Leeneer
Steve Lefever
Nick Sabbe
Filip Pattyn
Filip Van Nieuwerburgh
Paul Coucke
Dieter Deforce
Jo Vandesompele
Sofie Bekaert
et al.
A1
Artikel in een tijdschrift
in
BMC BIOINFORMATICS
2010
CEP290, a gene with many faces : mutation overview and presentation of CEP290base
Frauke Coppieters
Steve Lefever
Bart Leroy
Elfride De Baere
A1
Artikel in een tijdschrift
in
HUMAN MUTATION
2010
DNA-chipanalyse in de moleculaire diagnostiek van genetisch heterogene aandoeningen : netvliesaandoeningen als voorbeeld
Frauke Coppieters
Caroline Van Cauwenbergh
Barbara D'haene
Steve Lefever
Anne De Paepe
Bart Leroy
Elfride De Baere
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
The miRNA body map: dissecting miRNA function through integrative genomics
Pieter Mestdagh
Steve Lefever
Filip Pattyn
Dana Ridzon
Erik Fredlund
Annelies Fieuw
Joëlle Vermeulen
Anne De Paepe
Linda Wong
Franki Speleman
et al.
C3
Conferentie
2010
methGraph: A genome visualization tool for PCR-based methylation assays
Steve Lefever
Jasmien Hoebeeck
Filip Pattyn
Gábor Tusnády
Anne De Paepe
Franki Speleman
Tamás Arányi
Jo Vandesompele
A1
Artikel in een tijdschrift
in
EPIGENETICS
2010
2009
External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data
Joëlle Vermeulen
Filip Pattyn
Katleen De Preter
Liesbeth Vercruysse
Stefaan Derveaux
Pieter Mestdagh
Steve Lefever
Jan Hellemans
Franki Speleman
Jo Vandesompele
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2009
RDML : structured language and reporting guidelines for real-time quantitative PCR data
Steve Lefever
Jan Hellemans
Filip Pattyn
Daniel R Przybylski
Chris Taylor
René Geurts
Andreas Untergasser
Jo Vandesompele
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2009
RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts
Joëlle Vermeulen
Stefaan Derveaux
Steve Lefever
Els De Smet
Katleen De Preter
Nurten Yigit
Anne De Paepe
Filip Pattyn
Franki Speleman
Jo Vandesompele
A2
Artikel in een tijdschrift
in
BMC RESEARCH NOTES
2009
RTPrimerDB : the portal for real-time PCR primers and probes
Steve Lefever
Jo Vandesompele
Franki Speleman
Filip Pattyn
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2009
2007
Peptibolomics of the cows' udder: peptide profiling of the teat canal
Lukas Senepart
Valentijn Vergote
Adel Pezeshki
Samuel Bodé
Steve Lefever
Bram Baert
Kathelijne Peremans
Christian Paul G. Burvenich
Bart De Spiegeleer
C1
Conferentie
2007
Thyroid hormones and cortisol in lactating cows after intramammary LPS administration
Lukas Senepart
K WINTERS
Alessandra Gubbiotti
Steve Lefever
R BRUCKMAIER
J BLUM
G BERTONI
E TREVESI
C1
Conferentie
2007
Variation in gene expression of the TLR4 pathway in unstimulated circulating bovine neutrophils during early and mid lactation
Steve Lefever
A DE KETELAERE
Luc Duchateau
G VERMEULEN
Lukas Senepart
Bart De Spiegeleer
Luc Peelman
Christian Paul G. Burvenich
C1
Conferentie
2007
Variation in the underlying mechanisms of innate defense and outcome of bovine mammary E. coli infections
Christian Paul G. Burvenich
D BANNERMAN
Steve Lefever
Luc Peelman
Max Paape
C1
Conferentie
2007