Research Explorer

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Researcher

Roberto Vazquez Fernandez

Publications & Research Data

Awards & Distinctions

25 Results

2025

A deep dive into phage lytic machinery : structural and bioinformatic profiling of lytic proteins from newly isolated Pseudomonas aeruginosa bacteriophages

Marta Coelho BarbosaRoberto VázquezJoana AzeredoYves BriersSílvio Santos

A functional metagenomic pipeline for phage lysin discovery from environmental samples

Iris PottieLisa DuyvejonckTom Van de WieleRoberto VázquezYves Briers

Diversity, structure-function relationships and evolution of cell wall-binding domains of staphylococcal phage endolysins

Roberto VázquezDiana Gutierrez FernandezBjorn CrielZoë DezutterYves Briers

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Engineering phage lysins as novel antimicrobials using underexplored design and expression approaches

Emma CremelieYves BriersRoberto Vázquez

PhaLP 2.0 : a community-oriented database and portal for phage lysin research with new tailored computational tools and metagenomic data

Roberto VázquezAlexandre BoulayVictor NémethEmma CremelieBjorn CrielClovis GaliezElsa RousseauYves Briers

Sequence-based metagenomic approach for identifying lysins from sewage and pig feces

Iris PottieAlexandre BoulayLander De ConinckRoberto VázquezJelle MatthijnssensTom Van de WieleYves Briers

Skin microbiome-editing with novel antibiotics towards lower mosquito attraction

Magali De MuynckJoni BertRoberto VázquezChris CallewaertMarie JoossensYves Briers

SPAED : harnessing AlphaFold output for accurate segmentation of phage endolysin domains

Alexandre BoulayEmma CremelieClovis GaliezYves BriersElsa RousseauRoberto Vázquez

A1 Journal Article in BIOINFORMATICS

The new SH3b_T domain increases the structural and functional variability among SH3b-like CBDs from staphylococcal phage endolysins

Roberto VázquezDiana Gutierrez FernandezDennis GrimonLucía FernándezPilar GarcíaAna RodríguezYves Briers

A1 Journal Article in PROBIOTICS AND ANTIMICROBIAL PROTEINS

Understanding the role of amidase domains in bicatalytic staphylococcal endolysins

Seila AgúnRoberto VázquezLucía FernándezPilar GarcíaYves Briers

‘Exquisite specificity’, if the context allows : endolysin evolution is a contingent outcome of phage-host molecular landscapes

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielDennis GrimonRémy GoudeseuneJuan Roque Lizasoain VallejoSeila AgúnYves Briers

2024

A comparative guide to expression systems for phage lysin production

Emma CremelieRoberto VázquezYves Briers

A1 Journal Article in ESSAYS IN BIOCHEMISTRY

Dissecting the unknown specificity of cell wall-binding domains of phage endolysins

Roberto VázquezDiana Gutierrez FernandezZoë De ZutterBjorn CrielYves Briers

Hacking yeast cells with phage lysins to tackle bioethanol fermentation contaminants

Emma CremelieGilles VandermarliereRoberto VázquezYves Briers

Lessons learned from a systematic structural-functional characterization of cell wall binding domains (CBDs) from phage endolysins

Roberto VázquezDiana Gutierrez FernandezZoë de ZutterBjorn CrielYves Briers

Meeting report of the second symposium of the Belgian Society for Viruses of Microbes and launch of the Phage Valley

Salome DesmechtAgnieszka ŁątkaPieter-Jan CeyssensAbel Garcia-PinoAnnika GillisRob LavigneGipsi Lima-MendezJelle MatthijnssensRoberto VázquezJolien Venneman et al.

A1 Journal Article in VIRUSES-BASEL

Metagenomic exploration of phage-derived lysins for precise antibacterial action

Iris PottieLisa DuyvejonckRoberto VázquezYves Briers

Phage lysins for intestinal microbiome modulation : current challenges and enabling techniques

Iris PottieRoberto VázquezTom Van de WieleYves Briers

A1 Journal Article in GUT MICROBES

You get what you test for : the killing effect of phage lysins is highly dependent on buffer tonicity and ionic strength

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielPhilippe De GrooteYves Briers

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

2023

Breaking down walls : towards a functional-based metagenomic discovery platform for phage-derived lysins

Iris PottieLisa DuyvejonckRoberto VázquezYves Briers

Distinct mode of action of a highly stable, engineered phage lysin killing Gram-negative bacteria

Hans GerstmansLisa DuyvejonckRoberto VázquezInes StaesJimmy BorlooKarim Abdelkader Soufi AbdelkaderJeroen LeroyEmma CremelieDiana Gutierrez FernandezHéctor Tamés-Caunedo et al.

A1 Journal Article in MICROBIOLOGY SPECTRUM

Phage lysins as a promising alternative class of antibiotics : a metagenomics-driven high-throughput platform for the discovery of novel lysins

Lisa DuyvejonckIris PottieRoberto VázquezWannes Van WassenberghYves Briers

Structural and functional diversity of cell wall binding domains in staphylococcal endolysins

Roberto VázquezDiana Gutierrez FernandezBjorn CrielAna RodríguezPilar GarcíaYves Briers

Structural and functional diversity of staphylococcal cell wall binding domains

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielYves Briers

What's in a name? An overview of the proliferating nomenclature in the field of phage lysins

Roberto VázquezYves Briers

A1 Journal Article in CELLS