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Researcher
Olivier De Wever
Profile
Projects
Publications & Research Data
Activities
Awards & Distinctions
Patents
409
Results
2026
Exploration of patient-derived models as a tool to support therapeutic decision making in sarcoma patients
Stefanie Gijsels
Gabriëlle van Ramshorst
Olivier De Wever
Gwen Sys
Dissertation
2026
From pitfalls to progress in quantitative single-cell elemental analysis by time-of-flight ICP-mass spectrometry
Rinus Dejonghe
Ana Lores Padín
Eduardo Bolea Fernandez
Thibaut Van Acker
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
2026
Novel rectal cancer spheroid models reveal metabolic and transcriptional adaptations driving radiotherapy response
Diogo Miguel Monteiro Estêvão
Miguel da Cruz Ribeiro
Ana Canha-Borges
Catarina Macedo-Silva
Flávia Raquel Teixeira De Castro
Joana Lencart
Tom Boterberg
Olga Sousa
Carmen Jerónimo
Iola F. Duarte
et al.
A1
Journal Article
in
RADIOTHERAPY AND ONCOLOGY
2026
2025
A living sarcoma biobank for translational research purposes
Stefanie Gijsels
Merlijn Vekeman
Suzanne Fischer
David Creytens
Alexander Ackerman
Anaïs Ongenaet
Laurens Boi
Eline Segers
Jens De Temmerman
Francesca Casteur
et al.
C3
Conference
2025
Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profiling
The exRNAQC Consortium
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2025
CDX2 loss in colorectal cancer cells is associated with invasive properties and tumor budding
Nils Bodmer
Kristin Uth
Rina Mehmeti
Cansaran Saygili Demir
Deborah Stroka
Nassim Ghaffari-Tabrizi-Wizsy
Alessandro Lugli
Olivier De Wever
Inti Zlobec
Mario P. Tschan
A1
Journal Article
in
SCIENTIFIC REPORTS
2025
Chitosan/γ-PGA nanoparticles and IFN-γ immunotherapy : a dual approach for triple-negative breast cancer treatment
Flávia Raquel Teixeira De Castro
Marta Laranjeiro Pinto
Catarina Leite Pereira
Karine Serre
Ângela Margarida Costa
Bruno Cavadas
Mário Adolfo Barbosa
Karim Vermaelen
Sergio León
Diego Serrano
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2025
Engineered dendritic cells-derived extracellular vesicles for cancer immunotherapy
Margarida Oliveira Coelho
Sofia Torres Quintas
Bruno Sarmento
Olivier De Wever
Flávia Raquel Teixeira De Castro
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2025
Fibroblast activation protein on human natural killer cells : insights from natural killer cell activation and crosstalk with cancer-associated fibroblasts
Yentl Van Rymenant
Anke de Groot
Laura Dirkx
Emile Verhulst
Joni De Loose
Isabel Pintelon
Tias Verhezen
Jorrit De Waele
Sofie Thys
Olivier De Wever
et al.
A1
Journal Article
in
JOURNAL OF LEUKOCYTE BIOLOGY
2025
Identifying novel treatments for sarcoma through relevant surgical mouse models
Stefanie Gijsels
Suzanne Fischer
Lotte Legiest
Gabriëlle van Ramshorst
Gwen Sys
Olivier De Wever
C3
Conference
2025
Immune checkpoint inhibitors in gynecologic cancer : getting to prime T(I)ME?
Emiel De Jaeghere
Hannelore Denys
Olivier De Wever
Frédéric Amant
Dissertation
2025
Launching SMART 3D cancer models
Sam Ernst
Olivier De Wever
Editorial material
2025
Online microdroplet calibration for accurate elemental analysis via single-cell ICP-TOF-MS
Ana Lores Padín
Rinus Dejonghe
Olivier De Wever
Frank Vanhaecke
C3
Conference
2025
Preserving potential : surgeons as key partners in establishing a living sarcoma biobank for translational research purposes
Stefanie Gijsels
Merlijn Vekeman
Suzanne Fischer
David Creytens
Alexander Ackerman
Anaïs Ongenaet
Laurens Boi
Eline Segers
Jens De Temmerman
Francesca Casteur
et al.
A1
Journal Article
in
SURGICAL ONCOLOGY-OXFORD
2025
Repurposing itraconazole and pyrimethamine with temozolomide as a combinatorial treatment for glioblastoma
Thibault Lootens
Jelle Vandersteene
Harry Pinson
Sam Ernst
Tom Boterberg
Vanessa Vermeirssen
Olivier De Wever
Frederik De Smet
Robrecht Raedt
C3
Conference
2025
Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids
Eva Blondeel
Sam Ernst
Felix De Vuyst
Ákos Diósdi
Cláudio Pinheiro
Diogo Estêvão
Pekka Rappu
Robin Boiy
Sandor Dedeyne
Ligia Craciun
et al.
A1
Journal Article
in
NATURE PROTOCOLS
2025
Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids (Apr, 10.1038/s41596-025-01150-y, 2025)
Eva Blondeel
Sam Ernst
Felix De Vuyst
Ákos Diósdi
Cláudio Pinheiro
Diogo Miguel Monteiro Estêvão
Pekka Rappu
Robin Boiy
Sandor Dedeyne
Ligia Craciun
et al.
Correction
2025
Single-cell ICP-MS analysis of large human cells : addressing transport efficiency and size-dependent bias
Mina Nikolić
Ana Lores Padín
Thibaut Van Acker
Olivier De Wever
Eduardo Bolea Fernandez
Frank Vanhaecke
C3
Conference
2025
Spheroid-based tools as stepping stones towards rigorous and mechanistically insightful research.
Eva Blondeel
Olivier De Wever
Hannelore Denys
An Hendrix
Dissertation
2025
The Spheroid Light Microscopy Image Atlas for morphometrical analysis of three-dimensional cell cultures
Eva Blondeel
Arne Peirsman
Stephanie Vermeulen
Filippo Piccinini
Felix De Vuyst
Diogo Miguel Monteiro Estêvão
Sayida Al-Jamei
Martina Bedeschi
Gastone Castellani
Tânia Cruz
et al.
A1
Journal Article
in
SCIENTIFIC DATA
2025
Trash or treasure : biogenesis and func.On of extracellular vesicle subsets in hormone-positive breast cancer
Robin Boiy
An Hendrix
Olivier De Wever
Dissertation
2025
2024
An evaluation of the analytical and biological robustness of a method for quantifying iron in individual red blood cells via single-cell tandem ICP-mass spectrometry
Rinus Dejonghe
Eduardo Bolea Fernandez
Ana Lores Padín
Thibaut Van Acker
Ana Maria Rua Ibarz
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
MICROCHEMICAL JOURNAL
2024
Associations of the gut microbiome with outcomes in cervical and endometrial cancer patients treated with pembrolizumab : insights from the phase II PRIMMO trial
Emiel De Jaeghere
Hannelore Hamerlinck
Sandra Tuyaerts
Lien Lippens
An M.T. Van Nuffel
Regina Baiden-Amissah
Peter Vuylsteke
Stéphanie Henry
Xuan Bich Trinh
Peter A. van Dam
et al.
A1
Journal Article
in
GYNECOLOGIC ONCOLOGY
2024
Cancer‐associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer
Zihan Xia
Stephanie Vermeulen
Ujjwal Suwal
Pekka Rappu
Jyrki Heino
Felix De Vuyst
Sandor Dedeyne
An Hendrix
Hannelore Denys
Olivier De Wever
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL MEDICINE
2024
Clinical consequences of the increasing complexity of intratumour heterogeneity in soft-tissue sarcoma
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Alexander Ackerman
Laurens Boi
Eline Segers
Ruben Van Boxstael
Gwen Sys
Gabriëlle van Ramshorst
et al.
C3
Conference
2024
DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas
Gamze Bildik
Joshua P. Gray
Weiqun Mao
Hailing Yang
Rumeysa Ozyurt
Vivian R. Orellana
Olivier De Wever
Mark S. Carey
Robert C. Bast
Zhen Lu
A1
Journal Article
in
AUTOPHAGY
2024
Dual-ligand PROTACS mediate superior target protein degradation in vitro and therapeutic efficacy in vivo
Yong Chen
Zihan Xia
Ujjwal Suwal
Pekka Rappu
Jyrki Heino
Olivier De Wever
Bruno De Geest
A1
Journal Article
in
CHEMICAL SCIENCE
2024
Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts
Suzanne Fischer
David Creytens
Stefanie Gijsels
Benedicte Descamps
Lore Lapeire
An Hendrix
Gwen Sys
Olivier De Wever
A2
Journal Article
in
STAR PROTOCOLS
2024
Glioblastoma-associated mesenchymal stem/stromal cells and cancer-associated fibroblasts : partners in crime?
Thibault Lootens
Bart Roman
Christian Stevens
Olivier De Wever
Robrecht Raedt
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data
Cláudio Pinheiro
Niké Guilbert
Lien Lippens
Quentin Roux
Robin Boiy
Suzanne Fischer
Sofie Van Dorpe
Bram De Craene
Geert Berx
Tom Boterberg
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2024
Mapping bacterial extracellular vesicle research : insights, best practices and knowledge gaps
Nele De Langhe
Sofie Van Dorpe
Niké Guilbert
Amélie Vander Cruyssen
Quentin Roux
Sarah Deville
Sandor Dedeyne
Philippe Tummers
Hannelore Denys
Linos Vandekerckhove
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2024
Minimal information for studies of extracellular vesicles (MISEV2023) : from basic to advanced approaches
Joshua A. Welsh
Deborah C. I. Goberdhan
Lorraine O'Driscoll
Edit I. Buzas
Cherie Blenkiron
Benedetta Bussolati
Houjian Cai
Dolores Di Vizio
Tom A. P. Driedonks
Uta Erdbrügger
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2024
Navigating the complexity of intratumor heterogeneity in precision medicine
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Alexander Ackerman
Laurens Boi
Eline Segers
Ruben Van Boxstael
Gwen Sys
Gabriëlle van Ramshorst
et al.
C3
Conference
2024
PDXGhent : patient derived tumor xenografting mouse core facility Ghent
Liselot Mus
Steven Goossens
Tim Lammens
Lindsey Devisscher
Panagiotis Ntziachristos
Olivier De Wever
Frédéric Clement
C3
Conference
2024
PDXGhent : patient derived tumor xenografting mouse Core Facility Ghent
Liselot Mus
Steven Goossens
Tim Lammens
Lindsey Devisscher
Panagiotis Ntziachristos
Olivier De Wever
Frédéric Clement
C3
Conference
2024
Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties
Stephanie Vermeulen
Sam Ernst
Eva Blondeel
Zihan Xia
Pekka Rappu
Jyrki Heino
Sandor Dedeyne
Hannelore Denys
Gwen Sys
Stefanie Gijsels
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2024
Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study (vol 72, pg 475, 2022)
Emiel De Jaeghere
Sandra Tuyaerts
An M. T. Van Nufel
Ann Belmans
Kris Bogaerts
Regina Baiden-Amissah
Lien Lippens
Peter Vuylsteke
Stéphanie Henry
Xuan Bich Trinh
et al.
Correction
2024
Quantitative determination and subcellular mapping of Pt-based drugs in single breast tumour cells via laser ablation-ICP-mass spectrometry
Legna Colina Vegas
Thibaut Van Acker
Wilmer Villarreal
Olivier De Wever
Alzir Azevedo Batista
Joaquim Araújo Nóbrega
Frank Vanhaecke
A1
Journal Article
in
DALTON TRANSACTIONS
2024
Repurposing itraconazole and pyrimethamine with temozolomide as a combinatorial treatment for glioblastoma
Thibault Lootens
Jelle Vandersteene
Harry Pinson
Tom Boterberg
Vanessa Vermeirssen
Olivier De Wever
Frederik De Smet
Robrecht Raedt
C3
Conference
2024
Single tumour, many faces - unraveling intratumour complexity in soft-tissue sarcoma
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Alexander Ackerman
Laurens Boi
Eline Segers
Ruben Van Boxstael
Gwen Sys
Olivier De Wever
et al.
C3
Conference
2024
Single tumour, many faces : unraveling intratumour complexity of soft tissue sarcoma
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Alexander Ackerman
Laurens Boi
Eline Segers
Ruben Van Boxstael
Gabriëlle van Ramshorst
Gwen Sys
et al.
C3
Conference
2024
Single tumour, many faces : unraveling intratumour complexity of soft-tissue sarcoma
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Gabriëlle van Ramshorst
Gwen Sys
Olivier De Wever
C3
Conference
2024
Zebrafish avatars : toward functional precision medicine in low-grade serous ovarian cancer
Charlotte Fieuws
Jan Willem Bek
Bram Parton
Elyne De Neef
Olivier De Wever
Milena Hoorne
Marta F. Estrada
Jo Van Dorpe
Hannelore Denys
Koen Van de Vijver
et al.
A1
Journal Article
in
CANCERS
2024
2023
A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment
Elly De Vlieghere
Koen Van de Vijver
Eva Blondeel
Nathan Carpentier
Rouba Ghobeira
Jarne Pauwels
Sebastian Riemann
Manon Minsart
Charlotte Fieuws
Johanna Mestach
et al.
A1
Journal Article
in
BIOMATERIALS RESEARCH
2023
Analyzing extracellular vesicles in liquid biopsies : the road towards clinical application
Bert Dhondt
Nicolaas Lumen
An Hendrix
Olivier De Wever
Dissertation
2023
Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics
Bert Dhondt
Cláudio Pinheiro
Edward Geeurickx
Joeri Tulkens
Glenn Vergauwen
Edwin Van Der Pol
Rienk Nieuwland
Anneleen Decock
Ilkka Miinalainen
Pekka Rappu
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2023
Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics
Bert Dhondt
Cláudio Pinheiro
Edward Geeurickx
Joeri Tulkens
Glenn Vergauwen
Edwin Van Der Pol
Rienk Nieuwland
Anneleen Decock
Ilkka Miinalainen
Pekka Rappu
et al.
Research data
2023
Chronic exposure to dietary compounds shifts bioenergetics in colorectal cancer
Elien Alderweireldt
Charlotte Grootaert
Andreja Rajkovic
Filip Van Nieuwerburgh
John Van Camp
Olivier De Wever
C3
Conference
2023
Deep learning-based tool for morphotypic analysis of 3D multicellular spheroids
Filippo Piccinini
Arne Peirsman
Mariachiara Stellato
Jae-chul Pyun
Maria M. Tumedei
Marcella Tazzari
Olivier De Wever
Anna Tesei
Giovanni Martinelli
Gastone Castellani
A1
Journal Article
in
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY
2023
Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles
Quentin Roux
Robin Boiy
Felix De Vuyst
Mercedes Tkach
Cláudio Pinheiro
Sofie De Geyter
Ilkka Miinalainen
Clotilde Thery
Olivier De Wever
An Hendrix
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2023
Development of a live tissue sarcoma biobank to support the creation of patient-derived translational models
Merlijn Vekeman
Alexander Ackerman
Anaïs Ongenaet
Suzanne Fischer
Stefanie Gijsels
Olivier De Wever
An Hendrix
David Creytens
Gwen Sys
C3
Conference
2023
Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification
Fien Gysens
Lisa Ostyn
Ellen Goeteyn
Eva Blondeel
Justine Nuytens
Olivier De Wever
Eric de Bony de Lavergne
Aurélie Crabbé
Pieter Mestdagh
A1
Journal Article
in
SCIENTIFIC REPORTS
2023
Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
Thibaut D'huyvetter
et al.
C3
Conference
2023
Effect on colorectal cancer bioenergetics by chronic exposure to red meat metabolites
Elien Alderweireldt
Charlotte Grootaert
Sophie Van Welden
Debby Laukens
Andreja Rajkovic
John Van Camp
Olivier De Wever
C3
Conference
2023
Effect on colorectal cancer bioenergetics by chronic exposure to red meat metabolites
Elien Alderweireldt
Charlotte Grootaert
Andreja Rajkovic
Filip Van Nieuwerburgh
Stijn Luca
John Van Camp
Olivier De Wever
C3
Conference
2023
Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Teresa González-Muñoz
Angela Di Giannatale
Susana García-Silva
Vanesa Santos
Sara Sánchez-Redondo
Claudia Savini
Osvaldo Graña-Castro
Carmen Blanco-Aparicio
Suzanne Fischer
Olivier De Wever
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2023
Ex vivo sarcoma cell cultures from paired primary, local relapse and metastatic sites reveals phenotypic heterogeneity
Stefanie Gijsels
Suzanne Fischer
Laurens Boi
Eline Segers
Gwen Sys
Gabriëlle van Ramshorst
Olivier De Wever
C3
Conference
2023
Expanding the toolbox : development of tools to aid rigor and standardization in extracellular vesicle research
Cláudio Pinheiro
An Hendrix
Olivier De Wever
Dissertation
2023
Exploring spheroids in the light of adipose tissue engineering
Arne Peirsman
Phillip Blondeel
Olivier De Wever
Dissertation
2023
Histologic tumor type as a determinant of survival in hormone receptor-positive, HER2-negative, pT1-3 invasive ductal and lobular breast cancer
Menekse GOKER
Hannelore Denys
An Hendrix
Olivier De Wever
Koen Van de Vijver
Geert Braems
A1
Journal Article
in
BREAST CANCER RESEARCH
2023
Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility
Sofie Van Dorpe
Lien Lippens
Robin Boiy
Cláudio Pinheiro
Glenn Vergauwen
Pekka Rappu
Ilkka Miinalainen
Philippe Tummers
Hannelore Denys
Olivier De Wever
et al.
A1
Journal Article
in
JOURNAL OF NANOBIOTECHNOLOGY
2023
Orthotopic xenografts of paired sarcoma primary tumour, local relapse and metastatic sites reveals phenotypic heterogeneity in a minimal residual disease model
Stefanie Gijsels
Suzanne Fischer
David Creytens
Merlijn Vekeman
Alexander Ackerman
Gwen Sys
Gabriëlle van Ramshorst
Olivier De Wever
C3
Conference
2023
Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study
Emiel De Jaeghere
Sandra Tuyaerts
An M. T. Van Nuffel
Ann Belmans
Kris Bogaerts
Regina Baiden-Amissah
Lien Lippens
Peter Vuylsteke
Stéphanie Henry
Xuan Bich Trinh
et al.
A1
Journal Article
in
CANCER IMMUNOLOGY IMMUNOTHERAPY
2023
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2023
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2023
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts
Suzanne Fischer
David Creytens
Sofie De Geyter
Elly De Vlieghere
Piet Pattyn
Sarah-Lee Bekaert
Kaat Durinck
Nadine Van Roy
An Hendrix
Lore Lapeire
et al.
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL MEDICINE
2023
Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer
Cristina Muntean
Eva Blondeel
Laure Harinck
Kunal Pednekar
Jai Prakash
Olivier De Wever
Jeanne Leblond Chain
Stefaan De Smedt
Katrien Remaut
Koen Raemdonck
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2023
Rigor and standardization in extracellular vesicle research to enable clinical translation
Quentin Roux
An Hendrix
Olivier De Wever
Dissertation
2023
Selective modulation of cancer-associated fibroblasts in the tumor microenvironment by the small molecule inhibitor C16
Christophe Mangodt
Christian Stevens
Olivier De Wever
Bart Roman
Dissertation
2023
The impact of red meat metabolites on the metabolic flexibility of colon cancer cells
Elien Alderweireldt
John Van Camp
Olivier De Wever
Dissertation
2023
Vascularized adipose tissue engineering : moving towards soft tissue reconstruction
Arne Peirsman
Huu Tuan Nguyen
Michiel Van Waeyenberge
Carlos Ceballos
Johana Bolivar
Satoru Kawakita
Florian Vanlauwe
Zuzana Tirpakova
Sofie Van Dorpe
Lana Van Damme
et al.
A1
Journal Article
in
BIOFABRICATION
2023
2022
2022-RA-638-ESGO Pembrolizumab with multimodal immunomodulation in chemotherapy-pretreated cervical, endometrial, and uterine cancer : the PRIMMO phase II trial
Emiel De Jaeghere
Sandra Tuyaerts
Ann M.T. van Nuffel
Ann Belmans
Kris Bogaerts
Regina Baiden-Amissah
Peter Vuylsteke
Stéphanie Henry
Xuan Bich Trinh
Peter A. van Dam
et al.
C3
Conference
2022
A two-front nutritional environment fuels colorectal cancer : perspectives for dietary intervention
Elien Alderweireldt
Charlotte Grootaert
Olivier De Wever
John Van Camp
A1
Journal Article
in
TRENDS IN ENDOCRINOLOGY AND METABOLISM
2022
Effect of chronic exposure of dietary compounds on colorectal cancer bioenergetics
Elien Alderweireldt
Charlotte Grootaert
Andreja Rajkovic
John Van Camp
Olivier De Wever
C3
Conference
2022
Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles
Rahul Bhome
Muhammad Emaduddin
Victoria James
Louise M. House
Stephen M. Thirdborough
Massimiliano Mellone
Joeri Tulkens
John N. Primrose
Gareth J. Thomas
Olivier De Wever
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2022
Heterogeneity of CAFfeinated tumors : sweet targeting perspectives
Olivier De Wever
Editorial material
2022
Hybrid scaffolds as long-term in vitro co-culture model for targeted treatment of ovarian cancer
Elly De Vlieghere
Eva Blondeel
Nathan Carpentier
Koen Van de Vijver
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2022
Hybrid scaffolds to create long-term in vitro co-culture model for targeted treatment of ovarian cancer
Elly De Vlieghere
Eva Blondeel
Nathan Carpentier
Koen Van de Vijver
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2022
Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients
Suzanne Fischer
Elly De Vlieghere
David Creytens
Olivier De Wever
An Hendrix
Lore Lapeire
Gwen Sys
C3
Conference
2022
One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Julie Bellemans
Niels Vander Elst
Kristel Demeyere
Josephine De Vliegher
Timothy Perera
Olivier De Wever
Wim Van Den Broeck
Ward De Spiegelaere
Niek Sanders
et al.
A1
Journal Article
in
ONCOIMMUNOLOGY
2022
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
Thibaut D'huyvetter
et al.
Preprint
2022
Preclinical platform for long-term evaluation of drug efficacy using three-dimensional tumor-stroma spheroids embedded in stiffness-tunable scaffolds
Elly De Vlieghere
Eva Blondeel
Nathan Carpentier
Manon Minsart
Koen Van de Vijver
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2022
Single-event ICP-mass spectrometry analysis : faster data acquisition speed opens the way to novel applications
Eduardo Bolea Fernandez
Ana Maria Rua Ibarz
Lieve Balcaen
Thibaut Van Acker
Tong Liu
Frank Vanhaecke
Christophe Mangodt
Olivier De Wever
Glen Woods
Diego Leite
et al.
C3
Conference
2022
Systemically circulating bacterial extracellular vesicles : origin, fate, and function
An Hendrix
Olivier De Wever
Editorial material
2022
The first mitochondrial metastasis suppressor : NME4 loss-of-function impairs organelle structure and function
Uwe Schlattner
Marie-Lise Lacombe
Frédéric Lamarche
Cécile Cottet-Rousselle
Malgorzata Tokarska-Schlattner
Eric Fontaine
Olivier De Wever
Teresita Padilla-Benavides
Patricia Steeg
Béatrice Nawrocki-Raby
et al.
C3
Conference
2022
The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction
Evelien Wynendaele
Nathan Debunne
Yorick Janssens
Anton De Spiegeleer
Frederick Verbeke
Liesa Tack
Sophie Van Welden
Evy Goossens
Daniel Knappe
Ralf Hoffmann
et al.
A1
Journal Article
in
BMC BIOLOGY
2022
2021
A systematic review on extracellular vesicles-enriched fat grafting : a shifting paradigm
Mohammad Ghiasloo
Laura De Wilde
Kashika Singh
Patrick Tonnard
Alexis Verpaele
Olivier De Wever
Phillip Blondeel
A1
Journal Article
in
AESTHETIC SURGERY JOURNAL
2021
Automated liquid handling for highly specific and reproducible density‐based separation of extracellular vesicles from human body fluids
Sofie Van Dorpe
Lien Lippens
Robin Boiy
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2021
Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells
Aranit Harizaj
Benedicte Descamps
Christophe Mangodt
Stephan Stremersch
Arianna Stoppa
Lieve Balcaen
Toon Brans
Hilde De Rooster
Nausikaa Devriendt
Juan Fraire
et al.
A1
Journal Article
in
BIOMATERIALS SCIENCE
2021
Delivery routes matter : safety and efficacy of intratumoral immunotherapy
Emily De Lombaerde
Olivier De Wever
Bruno De Geest
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
2021
In vitro and in situ activity-based labeling of fibroblast activation protein with UAMC1110-derived probes
Yentl Van Rymenant
Muhammet Tanc
Roos Van Elzen
An Bracke
Olivier De Wever
Koen Augustyns
Anne-Marie Lambeir
Mark Kockx
Ingrid De Meester
Pieter Van Der Veken
A1
Journal Article
in
FRONTIERS IN CHEMISTRY
2021
Marine seagrass extract of Thalassia testudinum suppresses colorectal tumor growth, motility and angiogenesis by autophagic stress and immunogenic cell death pathways
Ivones Hernández-Balmaseda
Idania Rodeiro Guerra
Ken Declerck
José Alfredo Herrera Isidrón
Claudina Pérez-Novo
Guy Van Camp
Olivier De Wever
Kethia González
Mayrel Labrada
Adriana Carr
et al.
A1
Journal Article
in
MARINE DRUGS
2021
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance
Catalina Lodillinsky
Laetitia Fuhrmann
Marie Irondelle
Olena Pylypenko
Xiao-Yan Li
Hélène Bonsang-Kitzis
Fabien Reyal
Sophie Vacher
Claire Calmel
Olivier De Wever
et al.
A1
Journal Article
in
ONCOGENE
2021
MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity
Arne Peirsman
Eva Blondeel
Tasdiq Ahmed
Jasper Anckaert
Dominique Audenaert
Tom Boterberg
Krisztina Buzas
Neil Carragher
Gastone Castellani
Flávia Castro
et al.
A1
Journal Article
in
NATURE METHODS
2021
OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
A1
Journal Article
in
NPJ BREAST CANCER
2021
Patient-derived cell lines and xenografts from sarcoma patients as models for therapeutic decision making
Suzanne Fischer
David Creytens
Gwen Sys
Lore Lapeire
An Hendrix
Olivier De Wever
C3
Conference
2021
Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables
Edward Geeurickx
Lien Lippens
Pekka Rappu
Bruno De Geest
Olivier De Wever
An Hendrix
A1
Journal Article
in
NATURE PROTOCOLS
2021
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
Glenn Vergauwen
Joeri Tulkens
Cláudio Pinheiro
Francisco Avila Cobos
Sandor Dedeyne
Marie-Angélique De Scheerder
Linos Vandekerckhove
Francis Impens
Ilkka Miinalainen
Geert Braems
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2021
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
Ana Rita Pombo Antunes
Isabelle Scheyltjens
Francesca Lodi
Julie Messiaen
Asier Antoranz
Johnny Duerinck
Daliya Kancheva
Liesbet Martens
Karen De Vlaminck
Hannah Van Hove
et al.
A1
Journal Article
in
NATURE NEUROSCIENCE
2021
Single-event tandem ICP-mass spectrometry for the quantification of chemotherapeutic drug-derived Pt and endogenous elements in individual human cells
Tong Liu
Eduardo Bolea Fernandez
Christophe Mangodt
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2021
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2021
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2021
Targeting USP13 ‐mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in non‐small cell lung cancer
Philippe Giron
Carolien Eggermont
Amir Noeparast
Hugo Vandenplas
Erik Teugels
Ramses Forsyth
Olivier De Wever
Pedro Aza‐Blanc
Gustavo J. Gutierrez
Jacques De Grève
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2021
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor
Marie-Lise Lacombe
Frederic Lamarche
Olivier De Wever
Teresita Padilla-Benavides
Alyssa Carlson
Imran Khan
Anda Huna
Sophie Vacher
Claire Calmel
Céline Desbourdes
et al.
A1
Journal Article
in
BMC BIOLOGY
2021
Tissue engineered hybrid scaffold with relevant stiffness and extracellular matrix (ECM) as long-term in vitro model for low-grade serous ovarian carcinoma (LGSOC)
Elly De Vlieghere
Eva Blondeel
Nathan Carpentier
Sebastian Riemann
Wim Ceelen
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2021
Unexpected effects of a selective and potent c-MET inhibitor in an immunocompetent intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Annegret Van der Aa
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
C3
Conference
2021
2020
Analyzing bacterial extracellular vesicles in human body fluids by orthogonal biophysical separation and biochemical characterization
Joeri Tulkens
Olivier De Wever
An Hendrix
A1
Journal Article
in
NATURE PROTOCOLS
2020
Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma
René Delgado-Hernández
Ivones Hernández-Balmaseda
Idania Rodeiro-Guerra
Julio Cesar Rodriguez Gonzalez
Olivier De Wever
Emilie Logie
Ken Declerck
Claudina Pérez-Novo
Wim Vanden Berghe
A1
Journal Article
in
MELANOMA RESEARCH
2020
Chitosan/γ-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer
Flávia Castro
Marta L. Pinto
Catarina L. Pereira
Karine Serre
Mário A. Barbosa
Karim Vermaelen
Fátima Gärtner
Raquel M. Gonçalves
Olivier De Wever
Maria J. Oliveira
A1
Journal Article
in
BIOMATERIALS
2020
Development and application of a biological reference material for extracellular vesicle research
Edward Geeurickx
Olivier De Wever
An Hendrix
Sven Eycerman
Dissertation
2020
Effect of (processed) meat related compounds on intestinal organoids
Elien Alderweireldt
Charlotte Grootaert
Olivier De Wever
John Van Camp
C3
Conference
2020
Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
Elien De Thaye
Koen Van de Vijver
Joni Van der Meulen
Joachim Taminau
Glenn Wagemans
Hannelore Denys
Jo Van Dorpe
Geert Berx
Wim Ceelen
Jan Van Bocxlaer
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2020
Feasibility of mechanical extrusion to coat nanoparticles with extracellular vesicle membranes
Jan Van Deun
Quentin Roux
Sarah Deville
Thibaut Van Acker
Pekka Rappu
Ilkka Miinalainen
Jyrki Heino
Frank Vanhaecke
Bruno De Geest
Olivier De Wever
et al.
A1
Journal Article
in
CELLS
2020
Fructosamine-3-kinase as a potential treatment option for age-related macular degeneration
Sander De Bruyne
Caroline Van den Broecke
Henk Vrielinck
Samira Khelifi
Olivier De Wever
Ken Bracke
Manon Huizing
Nezahat Boston
Jonas Himpe
Marijn Speeckaert
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL MEDICINE
2020
In vivo selection of the MDA-MB-231br/eGFP cancer cell line to obtain a clinically relevant rat model for triple negative breast cancer brain metastasis
Valerie De Meulenaere
Benedicte Descamps
Olivier De Wever
Christian Vanhove
Karel Deblaere
A1
Journal Article
in
PLOS ONE
2020
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction
Joeri Tulkens
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Bert Dhondt
Lien Lippens
Marie-Angélique De Scheerder
Ilkka Miinalainen
Pekka Rappu
Bruno De Geest
et al.
A1
Journal Article
in
GUT
2020
Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients
Sandrine Herbelet
Elly De Vlieghere
Amanda Gonçalves
Boel De Paepe
Karsten Schmidt
Eline Nys
Laurens Weynants
Joachim Weis
Gert Van Peer
Jo Vandesompele
et al.
Bookchapter
in
Myokines, adipokines, cytokines in muscle pathophysiology
2020
MIFlowCyt-EV : a framework for standardized reporting of extracellular vesicle flow cytometry experiments
Joshua A. Welsh
Edwin Van Der Pol
Ger J.A. Arkesteijn
Michel Bremer
Alain Brisson
Frank Coumans
Françoise Dignat-George
Erika Duggan
Ionita Ghiran
Bernd Giebel
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2020
mTor inhibitor GDC-0349 improves ASO induced SAMMSON knock down resulting in enhanced anti-tumor efficacy in uveal melanoma
Shanna Dewaele
Boel De Paepe
Louis Delhaye
Eric de Bony de Lavergne
Jilke De Wilde
Katrien Vanderheyden
Jasper Anckaert
Nurten Yigit
Eveline Vanden Eynde
Fariba Nemati
et al.
C3
Conference
2020
Preparation of multi-omics grade extracellular vesicles by density-based fractionation of urine
Bert Dhondt
Nicolaas Lumen
Olivier De Wever
An Hendrix
A2
Journal Article
in
STAR PROTOCOLS
2020
Splenic 18F-FDG uptake on baseline PET/CT is associated with oncological outcomes and tumor immune state in uterine cervical cancer
Emiel De Jaeghere
Frederiek Laloo
Lien Lippens
Mieke Van Bockstal
Kathia De Man
Eline Naert
Jo Van Dorpe
Koen Van de Vijver
Philippe Tummers
Amin Makar
et al.
A1
Journal Article
in
GYNECOLOGIC ONCOLOGY
2020
Splenic hematopoietic and stromal cells in cancer progression
Jonas Steenbrugge
Emiel De Jaeghere
Evelyne Meyer
Hannelore Denys
Olivier De Wever
A1
Journal Article
in
CANCER RESEARCH
2020
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies
Anneleen Decock
Jasper Anckaert
Celine Everaert
Justine Nuytens
Scott Kuersten
An Hendrix
Jo Vandesompele
Pieter Mestdagh
Bert Dhondt
Ruben Van Paemel
et al.
C3
Conference
2020
Targeting the tumor microenvironment in colorectal peritoneal metastases
Wim Ceelen
Robert G. Ramsay
Vignesh Narasimhan
Alexander G. Heriot
Olivier De Wever
A1
Journal Article
in
TRENDS IN CANCER
2020
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
Liselot Mus
Irina Lambertz
Shana Claeys
Candy Kumps
Wouter Van Loocke
Christophe Van Neste
Ganesh Umapathy
Marica Vaapil
Christoph Bartenhagen
Genevieve Laureys
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2020
Tumor engineered model for low-grade serous ovarian carcinoma (LGSOC) : mimicking the tumor environment on a cellular and biophysical level
Elly De Vlieghere
Eva Blondeel
Wim Ceelen
Bruno De Geest
Geert Berx
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2020
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Bert Dhondt
Edward Geeurickx
Joeri Tulkens
Jan Van Deun
Glenn Vergauwen
Lien Lippens
Ilkka Miinalainen
Pekka Rappu
Jyrki Heino
Piet Ost
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2020
2019
A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy
Margo Steuperaert
Charlotte Debbaut
Charlotte Carlier
Olivier De Wever
Benedicte Descamps
Christian Vanhove
Wim Ceelen
Patrick Segers
A1
Journal Article
in
DRUG DELIVERY
2019
A supporting ecosystem to mature extracellular vesicles into clinical application
Olivier De Wever
An Hendrix
A1
Journal Article
in
EMBO JOURNAL
2019
Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma : a preclinical F98 glioblastoma rat model study
Valerie De Meulenaere
Ellen Bonte
Jeroen Verhoeven
Jean-Pierre Kalala Okito
Leen Pieters
Anne Vral
Olivier De Wever
Luc Leybaert
Ingeborg Goethals
Christian Vanhove
et al.
A1
Journal Article
in
PLOS ONE
2019
ALK positively regulates MYCN activity through repression of HBP1 expression
Shana Claeys
Geertrui Denecker
Kaat Durinck
Bieke Decaesteker
Liselot Mus
Siebe Loontiens
Suzanne Vanhauwaert
Kristina Althoff
Caroline Wigerup
Daniel Bexell
et al.
A1
Journal Article
in
ONCOGENE
2019
Cell line derived xenograft mouse models are a suitable in vivo model for studying tumor budding in colorectal cancer
Laurent M. C. Georges
Olivier De Wever
José A. Galván
Heather Dawson
Alessandro Lugli
Pieter Demetter
Inti Zlobec
A1
Journal Article
in
FRONTIERS IN MEDICINE
2019
Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells
Annemiek Uvyn
Ruben De Coen
Olivier De Wever
Kim Deswarte
Bart Lambrecht
Bruno De Geest
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2019
Cellular and sub-cellular Cu isotope fractionation in the human neuroblastoma SH-SY5Y cell line : proliferating versus neuron-like cells
Marta Costas Rodriguez
Legna Colina Vegas
Nikolay Solovyev
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2019
Comparative immune profiling of an aggressive 4T1-based versus a non-aggressive Py230-based intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Steven Van Laere
Evelyne Meyer
C3
Conference
2019
Comparative profiling of metastatic 4T1- vs. non-metastatic Py230-based mammary tumors in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Luc Dirix
Steven Van Laere
Evelyne Meyer
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conference
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conference
2019
Effect of processed meat related compounds on colon cells
Elien Alderweireldt
Charlotte Grootaert
Stefaan De Smet
Andreja Rajkovic
Olivier De Wever
John Van Camp
C3
Conference
2019
Effect of processed meat related compounds on colon cells
Elien Alderweireldt
Charlotte Grootaert
Stefaan De Smet
Andreja Rajkovic
Olivier De Wever
John Van Camp
C3
Conference
2019
Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Jill Deleu
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
et al.
C3
Conference
2019
Exploration of the urinary proteome in the search for new biomarkers for prostate cancer : a promising role for extracellular vesicles
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Lien Lippens
Joeri Tulkens
lkka Miinalainen
Pekka Rappu
Jyrki Heino Oulu, Finland
Piet Ost
et al.
C3
Conference
2019
Fibroblasts fuel immune escape in the tumor microenvironment
Emiel De Jaeghere
Hannelore Denys
Olivier De Wever
A1
Journal Article
in
TRENDS IN CANCER
2019
Laser ablation-tandem ICP-mass spectrometry (LA-ICP-MS/MS) imaging of iron oxide nanoparticles in Ca-rich gelatin microspheres
Thibaut Van Acker
Eduardo Bolea Fernandez
Elly De Vlieghere
Jingxian Gao
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
2019
Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer
Kaat De Clercq
Feifan Xie
Olivier De Wever
Benedicte Descamps
Anne Hoorens
An Vermeulen
Wim Ceelen
Chris Vervaet
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
Quantitative determination of Cu via LA-ICP-MS in single triple-negative breast tumor cells after treatment with a new Cu phosphine complex
Legna Colina-Vegas
Thibaut Van Acker
Wilmer Villarreal
Alzir Azevedo Batista
Olivier De Wever
Joaquim Araujo Nobrega
Frank Vanhaecke
C3
Conference
2019
Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models
Yves Depetter
Silke Geurs
Rob De Vreese
Sophie Goethals
Elien Vandoorn
Alien Laevens
Jonas Steenbrugge
Evelyne Meyer
Pascal de Tullio
Marc Bracke
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2019
Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound
Silke Roovers
Joke Deprez
D Priwitaningrum
G Lajoinie
N Rivron
Heidi Declercq
Olivier De Wever
E Stride
S Le Gac
M Versluis
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2019
Splenic metabolic activity as biomarker in cervical cancer
Emiel De Jaeghere
Frederiek Laloo
Lien Lippens
Kathia De Man
Mieke Van Bockstal
Koen Van de Vijver
Philippe Tummers
Amin Makar
Pieter De Visschere
Olivier De Wever
et al.
C3
Conference
2019
Stromal integrin α11 regulates PDGFRβ signaling and promotes breast cancer progression
Irina Primac
Erik Maquoi
Silvia Blacher
Ritva Heljasvaara
Jan Van Deun
Hilde YH Smeland
Annalisa Canale
Thomas Louis
Linda Stuhr
Nor Eddine Sounni
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL INVESTIGATION
2019
Synthesis of indoline‐based benzhydroxamic acids as potential HDAC6 inhibitors
Yves Depetter
Silke Geurs
Jorick Franceus
Damijan Knez
Tom Desmet
Karolien De Bosscher
Olivier De Wever
Stanislav Gobec
Matthias D'hooghe
A1
Journal Article
in
CHEMISTRYSELECT
2019
Synthesis of selective HDAC6 inhibitors and their evaluation in cancer models
Yves Depetter
Matthias D'hooghe
Olivier De Wever
Dissertation
2019
The effect of processed meat related compounds on colon cells : relevance of long term approach
Elien Alderweireldt
Charlotte Grootaert
Stefaan De Smet
Olivier De Wever
John Van Camp
C1
Conference
2019
The generation and use of recombinant extracellular vesicles as biological reference material
Edward Geeurickx
Joeri Tulkens
Bert Dhondt
Jan Van Deun
Lien Lippens
Glenn Vergauwen
Elisa Heyrman
Delphine De Sutter
Kris Gevaert
Francis Impens
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
Tumor engineered model for peritoneal metastasis with controllable stiffness
Elly De Vlieghere
Wim Ceelen
Bruno De Geest
Heidi Declercq
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2019
Tumor engineered scaffolds recapitulate a human peritoneal tumor environment at the cellular and biophysical level
Elly De Vlieghere
Wim Ceelen
Bruno De Geest
Heidi Declercq
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2019
Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo
Elly De Vlieghere
Emiel De Jaeghere
Glenn Wagemans
Thibaut Van Acker
Christian Vanhove
Sarah Neyts
Geert Berx
Frank Vanhaecke
Wim Ceelen
Bruno De Geest
et al.
C3
Conference
2019
2018
A new Ru(II) complex : DNA/HSA-binding, anti-migration and biological properties in a human breast tumor cell line
Legna Colina-Vegas
Thibaut Van Acker
Olivier De Wever
Alzir Azevedo Batista
Joaquim Araujo Nobrega
Frank Vanhaecke
C3
Conference
2018
Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge
Koen Breyne
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Cecile Colpaert
Peter Vermeulen
Steven Van Laere
Evelyne Meyer
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
2018
Applications of laser ablation-inductively coupled plasma-mass spectrometry imaging in experimental peritoneal metastatic cancer research regarding tissue engineered biomaterials
Thibaut Van Acker
Elly De Vlieghere
Eduardo Bolea Fernandez
Olivier De Wever
Frank Vanhaecke
C3
Conference
2018
Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition
Yves Depetter
Silke Geurs
Flore Vanden Bussche
Rob De Vreese
Jorick Franceus
Tom Desmet
Olivier De Wever
Matthias D'hooghe
A1
Journal Article
in
MEDCHEMCOMM
2018
Bursting the bubble : introducing rigor in extracellular vesicle research to track and target cancer
Jan Van Deun
Olivier De Wever
An Hendrix
Dissertation
2018
Children’s screen time alters the expression of saliva extracellular miR-222 and miR-146a
Annette Vriens
Eline B Provost
Nelly D Saenen
Patrick De Boever
Karen Vrijens
Olivier De Wever
Michelle Plusquin
Tim S Nawrot
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts
Zuzanna Drebert
Elly De Vlieghere
Jolien Bridelance
Olivier De Wever
Karolien De Bosscher
Marc Bracke
Ilse Beck
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2018
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
Olivier De Wever
Emiel De Jaeghere
Elly De Vlieghere
C3
Conference
2018
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
Emiel De Jaeghere
Elly De Vlieghere
Jasper Van Hoorick
Sandra Van Vlierberghe
Glenn Wagemans
Leen Pieters
Elodie Melsens
Marleen Praet
Jo Van Dorpe
Matthieu Boone
et al.
A1
Journal Article
in
BIOMATERIALS
2018
Hypoxia imaging with 18F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts
Elodie Melsens
Elly De Vlieghere
Benedicte Descamps
Christian Vanhove
Ken Kersemans
Filip De Vos
Ingeborg Goethals
Boudewijn Brans
Olivier De Wever
Wim Ceelen
et al.
A1
Journal Article
in
RADIATION ONCOLOGY
2018
Impact of the microenvironment on tumour budding in colorectal cancer
Laurent MC Georges
Laurine Verset
Inti Zlobec
Pieter Demetter
Olivier De Wever
A1
Journal Article
in
Advances in Experimental Medicine and Biology
2018
Intravasation of SW620 colon cancer cell spheroids through the blood endothelial barrier is inhibited by clinical drugs and flavonoids in vitro
Silvio Holzner
Stefan Brenner
Atanas Georgiev Atanasov
Daniel Senfter
Serena Stadler
Chi Huu Nguyen
Adryan Fristiohady
Daniela Milovanovic
Nicole Huttary
Sigurd Krieger
et al.
A1
Journal Article
in
FOOD AND CHEMICAL TOXICOLOGY
2018
Is there a role for quorum sensing peptides in cancer?
Evelien Wynendaele
Yorick Janssens
Nathan Debunne
Olivier De Wever
Bart De Spiegeleer
C3
Conference
2018
Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma
Elmina Mammadova-Bach
Tristan Rupp
Caroline Spenlé
Ivo Jivkov
Pattabhiraman Shankaranarayanan
Annick Klein
Laura Pisarsky
Agnès Méchine-Neuville
Gérard Cremel
Michèle Kedinger
et al.
A1
Journal Article
in
BIOLOGY OF THE CELL
2018
Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients
Sandrine Herbelet
Elly De Vlieghere
Amanda Gonçalves
Boel De Paepe
Karsten Schmidt
Eline Nys
Laurens Weynants
Joachim Weis
Gert Van Peer
Jo Vandesompele
et al.
A1
Journal Article
in
FRONTIERS IN PHYSIOLOGY
2018
Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Théry
Kenneth W Witwer
Elena Aikawa
Maria Jose Alcaraz
Johnathon D Anderson
Ramaroson Andriantsitohaina
Anna Antoniou
Tanina Arab
Fabienne Archer
Georgia K Atkin-Smith
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2018
Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation
Joke Tommelein
Elly De Vlieghere
Laurine Verset
Elodie Melsens
Justine Leenders
Benedicte Descamps
Annelies Debucquoy
Christian Vanhove
Patrick Pauwels
Christian P Gespach
et al.
A1
Journal Article
in
CANCER RESEARCH
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Elisa Heyrman
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Ilkka Miinalainen
et al.
C3
Conference
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Elisa Heyrman
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Ilkka Miinalainen
et al.
C3
Conference
2018
Repeatable, high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Ilkka Miinalainen
Pekka Rappu
Jyrki Heino
Nicolaas Lumen
et al.
C3
Conference
2018
Reproduceerbare isolatie van hoog-zuivere urinaire extracellulaire vesikels voor uro-oncologische biomerkerstudies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Filip Poelaert
Tom Claeys
et al.
C3
Conference
2018
Reproducible high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Ilkka Miinalainen
Pekka Rappu
et al.
C3
Conference
2018
Reproducible isolation of high-purity urinary extracellular vesicles for uro-oncological biomarker studies
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Joeri Tulkens
Lien Lippens
Sarah Buelens
Elise De Bleser
Filip Poelaert
Tom Claeys
et al.
C3
Conference
2018
Some diffuse large B cell lymphomas (DLBCLs) present with clone-dependent TTF-1 positivity
Mieke Van Bockstal
Alessandra Camboni
Elly De Vlieghere
Frederic De Ryck
Ann-Sophie Candaele
SOFIE GEENEN
Lies Vandemaele
Olivier De Wever
Louis Libbrecht
Sofie Verbeke
et al.
A1
Journal Article
in
HISTOPATHOLOGY
2018
Species-dependent extracranial manifestations of a brain seeking breast cancer cell line
Valerie De Meulenaere
Sara Neyt
Bert Vandeghinste
Pieter Mollet
Olivier De Wever
Elke Decrock
Luc Leybaert
Ingeborg Goethals
Christian Vanhove
Benedicte Descamps
et al.
A1
Journal Article
in
PLOS ONE
2018
Synthesis of C-ring-modified blebbistatin derivatives and evaluation of their myosin II ATPase inhibitory potency
Bart Roman
Sigrid Verhasselt
Christophe Mangodt
Olivier De Wever
Christian Stevens
A1
Journal Article
in
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
2018
Targeting Polo-like kinase 1 and TRAIL enhances apoptosis in non-small cell lung cancer
Alfiah Noor
Ijeoma Adaku Umelo
Peter Kronenberger
Philipe Giron
Elly De Vlieghere
Olivier De Wever
Erik Teugels
Jacques De Grève
A2
Journal Article
in
ONCOTARGET
2018
The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine
Francisco Avila Cobos
Anneleen Decock
Katleen De Preter
Bert Dhondt
Olivier De Wever
Bram De Wilde
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conference
2018
The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine
Francisco Avila Cobos
Anneleen Decock
Katleen De Preter
Olivier De Wever
Bram De Wilde
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conference
2018
The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)
Lien Lippens
Robin Boiy
Bert Dhondt
Bruno De Geest
Katrien Vandecasteele
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2018
Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis
Robin Boiy
Jonas Steenbrugge
Jan Van Deun
An Hendrix
Evelyne Meyer
Olivier De Wever
A1
Journal Article
in
CLINICAL & EXPERIMENTAL METASTASIS
2018
Tumor immune profiling and host NF-kappaB activity assessment in a novel Py230-based intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Niek Sanders
Olivier De Wever
Steven Van Laere
Evelyne Meyer
C3
Conference
2018
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation
Julie Jacobs
Vanessa Deschoolmeester
Karen Zwaenepoel
Tal Flieswasser
Christophe Deben
Jolien Van den Bossche
Christophe Hermans
Christian Rolfo
Marc Peeters
Olivier De Wever
et al.
A1
Journal Article
in
ONCOIMMUNOLOGY
2018
Urinary extracellular vesicle biomarkers in urological cancers : from discovery towards clinical implementation
Bert Dhondt
Jan Van Deun
Silke Vermaerke
Ario de Marco
Nicolaas Lumen
Olivier De Wever
An Hendrix
A1
Journal Article
in
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
2018
2017
A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer
Mieke Van Bockstal
Nadine Van Roy
Glenn Vergauwen
Kathleen Lambein
Veronique Cocquyt
Louis Libbrecht
Hannelore Denys
Marc Bracke
Olivier De Wever
C3
Conference
2017
ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer
Laurine Verset
Joke Tommelein
Christine Decaestecker
Elly De Vlieghere
Marc Bracke
Isabelle Salmon
Olivier De Wever
Pieter Demetter
A1
Journal Article
in
TUMOR BIOLOGY
2017
Cancer cell lysate entrapment in CaCO3 engineered with polymeric TLR-agonists : immune-modulating microparticles in view of personalized antitumor vaccination
Lien Lybaert
Keun Ah Ryu
Lutz Nuhn
Riet De Rycke
Olivier De Wever
Alfred C Chon
Aaron P Esser-Kahn
Bruno De Geest
A1
Journal Article
in
CHEMISTRY OF MATERIALS
2017
Circulating extracellular vesicles in cancer : a strategy to unlock hidden secrets
Glenn Vergauwen
Rudy Van den Broecke
Olivier De Wever
An Hendrix
Dissertation
2017
Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling
Serena Stadler
Chi Huu Nguyen
Helga Schachner
Daniela Milovanovic
Silvio Holzner
Stefan Brenner
Julia Eichsteininger
Mira Stadler
Daniel Senfter
Liselotte Krenn
et al.
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2017
Confounding factors in extracellular vesicle ultrafiltration and protein analysis
Glenn Vergauwen
Bert Dhondt
Jan Van Deun
Evy Timmerman
Kris Gevaert
Geert Braems
Rudy Van den Broecke
Veronique Cocquyt
Hannelore Denys
Olivier De Wever
et al.
C3
Conference
2017
Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research
Glenn Vergauwen
Bert Dhondt
Jan Van Deun
Eva De Smedt
Geert Berx
Evy Timmerman
Kris Gevaert
Ilkka Miinalainen
Veronique Cocquyt
Geert Braems
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
Developments and future clinical outlook of taxane nanomedicines
Benoit Louage
Olivier De Wever
Wim E Hennink
Bruno De Geest
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2017
Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties
Sigrid Verhasselt
Bart Roman
Olivier De Wever
Kristof Van Hecke
Rik Van Deun
Marc Bracke
Christian Stevens
A1
Journal Article
in
ORGANIC & BIOMOLECULAR CHEMISTRY
2017
EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Patrizia Agostinis
Özden Akay
Sushma Anand
Jasper Anckaert
Zoraida Andreu Martinez
Tine Baetens
Els Beghein
Laurence Bertier
et al.
A1
Journal Article
in
NATURE METHODS
2017
Exosomal microRNAs derived from colorectal cancer-associated fibroblasts : role in driving cancer progression
Rahul Bhome
Rebecca W Goh
Marc D Bullock
Nir Pillar
Stephen M Thirdborough
Massimiliano Mellone
Reza Mirnezami
Dieter Galea
Kirill Veselkov
Quan Gu
et al.
A1
Journal Article
in
AGING-US
2017
Heterocellular 3D scaffolds as biomimetic of peritoneal metastases
Elly De Vlieghere
Emiel De Jaeghere
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Sara Neyt
Bruno De Geest
Peter Dubruel
Wim Ceelen
et al.
C3
Conference
2017
Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
Emiel De Jaeghere
Elly De Vlieghere
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Sara Neyt
Rouba Ghobeira
Rino Morent
Jo Van Dorpe
et al.
C3
Conference
2017
Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
Elly De Vlieghere
Emiel De Jaeghere
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Sara Neyt
Bruno De Geest
Peter Dubruel
Wim Ceelen
et al.
C3
Conference
2017
Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
Elly De Vlieghere
Emiel De Jaeghere
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Sara Neyt
Bruno De Geest
Peter Dubruel
Wim Ceelen
et al.
C3
Conference
2017
Identification of confounding factors of EV isolation and protein analysis
Glenn Vergauwen
Bert Dhondt
Jan Van Deun
Evy Timmerman
Kris Gevaert
Veronique Cocquyt
Geert Braems
Rudy Van den Broecke
Hannelore Denys
Olivier De Wever
et al.
C3
Conference
2017
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection
Elodie Melsens
Elly De Vlieghere
Benedicte Descamps
Christian Vanhove
Olivier De Wever
Wim Ceelen
Piet Pattyn
A1
Journal Article
in
ONCOLOGY REPORTS
2017
In vivo visualisation of vessel formation in peritoneal tumour scaffolds with μCT
Emiel De Jaeghere
Elly De Vlieghere
Sara Neyt
Bert Vandeghinste
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Geert Berx
Sandra Van Vlierberghe
et al.
C3
Conference
2017
Mathematical modeling of intraperitoneal drug delivery : simulation of drug distribution in a single tumor nodule
Margo Steuperaert
Giuseppe Falvo D'Urso Labate
Charlotte Debbaut
Olivier De Wever
Christian Vanhove
Wim Ceelen
Patrick Segers
A1
Journal Article
in
DRUG DELIVERY
2017
Methodological guidelines to study extracellular vesicles
Frank AW Coumans
Alain R Brisson
Edit I Buzas
Françoise Dignat-George
Esther EE Drees
Samir El-Andaloussi
Costanza Emanueli
Aleksandra Gasecka
An Hendrix
Andrew F Hill
et al.
A1
Journal Article
in
CIRCULATION RESEARCH
2017
mRNA capture sequencing enabled liquid biopsy screening
Anneleen Decock
Olivier De Wever
Bert Dhondt
Carolina Fierro
An Hendrix
Hetty Helsmoortel
Scott Kuersten
Pieter Mestdagh
Nele Nijs
Piet Ost
et al.
C3
Conference
2017
Multimodal imaging in an experimental rat model for brain metastasis
Valerie De Meulenaere
Christian Vanhove
Sara Neyt
Bert Vandeghinste
Elke Decrock
Olivier De Wever
Benedicte Descamps
Karel Deblaere
C3
Conference
2017
Polyelectrolyte-enrobed cancer cells in view of personalized immune-therapy
Lien Lybaert
Keun Ah Ryu
Riet De Rycke
Alfred C Chon
Olivier De Wever
Karim Vermaelen
Aaron Esser-Kahn
Bruno De Geest
A1
Journal Article
in
ADVANCED SCIENCE
2017
Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (OptiprepTM) density gradient
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Tom Claeys
Filip Poelaert
Sarah Buelens
Nicolaas Lumen
An Hendrix
Olivier De Wever
C3
Conference
2017
Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (Optiprep™) density gradient
Bert Dhondt
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Tom Claeys
Filip Poelaert
Sarah Buelens
An Hendrix
Olivier De Wever
Nicolaas Lumen
C3
Conference
2017
Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth
Lore Lapeire
An Hendrix
Evelyne Lecoutere
Mieke Van Bockstal
Jo Vandesompele
Dawn Maynard
Geert Braems
Rudy Van den Broecke
Cathérine Müller
Marc Bracke
et al.
A1
Journal Article
in
ONCOTARGET
2017
Stromal reaction and paracrine consequences of radiotherapy in colorectal cancer
Joke Tommelein
Olivier De Wever
Marc Bracke
Dissertation
2017
The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma
Liselot Mus
Irina Lambertz
Candy Kumps
Shana Claeys
Geertrui Denecker
Wouter Van Loocke
Christophe Van Neste
Jan Koster
Rogier Versteeg
Nadine Van Roy
et al.
C3
Conference
2017
The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma
Liselot Mus
Irina Lambertz
Candy Kumps
Shana Claeys
Geertrui Denecker
Wouter Van Loocke
Christophe Van Neste
Jan Koster
Rogier Versteeg
Nadine Van Roy
et al.
C3
Conference
2017
The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma
Liselot Mus
Irina Lambertz
Candy Kumps
Shana Claeys
Geertrui Denecker
Wouter Van Loocke
Christophe Van Neste
Jan Koster
Rogier Versteeg
Nadine Van Roy
et al.
C3
Conference
2017
The extracellular RNA quality control (exRNAQC) study : testing and controlling pre-analytical variables of RNA sequencing on liquid biopsies
Anneleen Decock
Olivier De Wever
Bert Dhondt
Thibaut D'huyvetter
Hetty Helsmoortel
An Hendrix
Annouck Philippron
Kimberly Verniers
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2017
The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome
Lotte Pyfferoen
Elisabeth Brabants
Celine Everaert
Nancy De Cabooter
Kelly Heyns
Kim Deswarte
Manon Vanheerswynghels
Sofie De Prijck
Glenn Waegemans
Melissa Dullaers
et al.
A1
Journal Article
in
ONCOIMMUNOLOGY
2017
Tumour tissue transport after intraperitoneal anticancer drug delivery
Charlotte Carlier
Ada Mathys
Emiel De Jaeghere
Margo Steuperaert
Olivier De Wever
Wim Ceelen
A1
Journal Article
in
INTERNATIONAL JOURNAL OF HYPERTHERMIA
2017
When neighbors talk : colon cancer cell invasion and tumor microenvironment myofibroblasts
Jolien Bridelance
Zuzanna Drebert
Olivier De Wever
Marc Bracke
Ilse Beck
A1
Journal Article
in
CURRENT DRUG TARGETS
2017
2016
Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts
Joke Tommelein
Félix Gremonprez
Laurine Verset
Elly De Vlieghere
Glenn Wagemans
Christian Gespach
Tom Boterberg
Pieter Demetter
Wim Ceelen
Marc Bracke
et al.
A1
Journal Article
in
ONCOTARGET
2016
APOBEC3G expression correlates with T-cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma
Brandon Leonard
Gabriel J Starrett
Matthew J Maurer
Ann L Oberg
Mieke Van Bockstal
Jo Van Dorpe
Olivier De Wever
Jozien Helleman
Anieta M Sieuwerts
Els MJJ Berns
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2016
Chitinase 3-like 1 as breast cancer metastasis biomarker for differential tumor progression in the intraductal versus the fat pad preclinical model
Jonas Steenbrugge
Koen Breyne
Sofie Denies
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Niek Sanders
Evelyne Meyer
C3
Conference
2016
Comparison of the adipose and luminal mammary gland compartment as orthotopic inoculation sites in a 4T1-based immunocompetent preclinical model for triple-negative breast cancer
Jonas Steenbrugge
Koen Breyne
Sofie Denies
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Peter Vermeulen
Steven Van Laere
Niek Sanders
Evelyne Meyer
A1
Journal Article
in
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
2016
Dissemination and adhesion of peritoneal cancer cells to the peritoneal wall
Elly De Vlieghere
Marc Bracke
Laurine Verset
Pieter Demetter
Olivier De Wever
Bookchapter
in
Intraperitoneal cancer therapy : principles and practice
2016
ETV5 functionally connect ALK and CXCR4 signaling in neuroblastoma
Irina Lambertz
Shana Claeys
Candy Kumps
Liselot Mus
Els Janssens
Nadine Van Roy
Bram De Wilde
Genevieve Laureys
Jan Cools
Olivier De Wever
et al.
C3
Conference
2016
ETV5 functionally connects ALK and CXCR4 signaling in neuroblastoma
Irina Lambertz
Liselot Mus
Candy Kumps
Shana Claeys
Nadine Van Roy
Bram De Wilde
Genevieve Laureys
Johannes Shulte
Olivier De Wever
Katleen De Preter
et al.
C3
Conference
2016
EV-TRAQ: tracking transparent reporting and quality to boost standardized extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Jasper Anckaert
Jo Vandesompele
Olivier De Wever
An Hendrix
C3
Conference
2016
FHL2 : a scaffold protein of carcinogenesis, tumour-stroma interactions and treatment response
Laurine Verset
Lynn Feys
Anne-Laure Trepant
Olivier De Wever
Pieter Demetter
A1
Journal Article
in
HISTOLOGY AND HISTOPATHOLOGY
2016
Function of extracellular vesicle-associated miRNAs in metastasis
Bert Dhondt
Quentin Rousseau
Olivier De Wever
An Hendrix
A1
Journal Article
in
CELL AND TISSUE RESEARCH
2016
Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions : in vitro and in vivo characterization
Kaat De Clercq
Charlotte Schelfhout
Marc Bracke
Olivier De Wever
Mieke Van Bockstal
Wim Ceelen
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
BIOMATERIALS
2016
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity
María Díaz-Núñez
Alejandro Díez-Torre
Olivier De Wever
Ricardo Andrade
Jon Arluzea
Margarita Silió
Juan Aréchaga
A1
Journal Article
in
BMC CANCER
2016
Isolation of extracellular vesicles from urine samples
Bert Dhondt
Nicolaas Lumen
An Hendrix
Olivier De Wever
C3
Conference
2016
Isolation of urinary extracellular vesicles for uro-oncological biomarker studies is complicated by Tamm-Horsfall protein
Bert Dhondt
Delphine Daveloose
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Tom Claeys
Filip Poelaert
An Hendrix
Olivier De Wever
Nicolaas Lumen
C3
Conference
2016
Mapping the methodological diversity of EV isolation and characterization
Jan Van Deun
Pieter Mestdagh
Jo Vandesompele
Olivier De Wever
An Hendrix
C3
Conference
2016
Nanoscopic tumor tissue distribution of platinum after intraperitoneal administration in a xenograft model of ovarian cancer
Charlotte Carlier
Brecht Laforce
Stijn Van Malderen
Félix Gremonprez
Remi Tucoulou
Julie Villanova
Olivier De Wever
Frank Vanhaecke
Wim Ceelen
Laszlo Vincze
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2016
NewTumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
Elly De Vlieghere
Marc Bracke
Pieter Demetter
Wim Ceelen
Christian Vanhove
Bruno De Geest
Olivier De Wever
C3
Conference
2016
NFAT5 in Duchenne muscular dystrophy cultured myoblasts after exposure to hyperosmolar salt conditions
Sandrine Herbelet
Amanda Gonçalves
Elly De Vlieghere
Gert Van Peer
Boel De Paepe
Chris Guerin
Jo Vandesompele
Olivier De Wever
Jan De Bleecker
C3
Conference
2016
NFAT5 in inflammatory myopathies and Duchenne muscular dystrophy
Sandrine Herbelet
Amanda Gonçalves
Elly De Vlieghere
Boel De Paepe
Chris Guerin
Olivier De Wever
Jan De Bleecker
C3
Conference
2016
Quantitative and functional requirements for bioluminescent cancer models
Lynn Feys
Benedicte Descamps
Christian Vanhove
Stefan Vermeulen
Jo Vandesompele
Katrien Vanderheyden
Kathy Messens
marc bracke
Olivier De Wever
A1
Journal Article
in
IN VIVO
2016
Quantitative evaluation of single cell spread on collagen matrices
Elly De Vlieghere
Glenn Wagemans
S De Backer
Zuzanna Drebert
Joke Tommelein
Quentin Rousseau
B Weyn
Marleen Van Troys
Marc Bracke
Olivier De Wever
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2016
Radiation-induced collateral damage : impact on metastasis
Lynn Feys
Olivier De Wever
Marc Bracke
Other
2016
Radiation-induced collateral damage : impact on metastasis
Lynn Feys
Marc Bracke
Olivier De Wever
Dissertation
2016
Recent exposure to ultrafine particles in school children alters miR-222 expression in the extracellular fraction of saliva
Annette Vriens
Tim S Nawrot
Nelly D Saenen
Eline B Provost
Michal Kicinski
Wouter Lefebvre
Charlotte Vanpoucke
Jan Van Deun
Olivier De Wever
Karen Vrijens
et al.
A1
Journal Article
in
ENVIRONMENTAL HEALTH
2016
Sensing mutant ALK: Capicua and ETV5 as executors of aberrant ALK-driven MAPK signaling
Irina Lambertz
Liselot Mus
Candy Kumps
Shana Claeys
Wouter Van Loocke
Christophe Van Neste
Jan Koster
Rogier Versteeg
Nadine Van Roy
Bram De Wilde
et al.
C3
Conference
2016
SMARCAD1 knockdown uncovers its role in breast cancer cell migration, invasion, and metastasis
Elham Al Kubaisy
Kholoud Arafat
Olivier De Wever
Ahmed H Hassan
Samir Attoub
A1
Journal Article
in
EXPERT OPINION ON THERAPEUTIC TARGETS
2016
The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors
Sandrine Herbelet
Elly De Vlieghere
Amanda Gonçalves
Boel De Paepe
Chris Guerin
Olivier De Wever
Jan De Bleecker
C3
Conference
2016
The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors
Sandrine Herbelet
Elly De Vlieghere
Gert Van Peer
Boel De Paepe
Eline Nys
Laurens Weynants
Jo Vandesompele
Olivier De Wever
Jens Schmidt
Jan De Bleecker
C3
Conference
2016
The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome
Yorick Janssens
Evelien Wynendaele
Frederick Verbeke
An Hendrix
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2016
Transiently responsive block copolymer micelles based on N-(2-hydroxypropyl)methacrylamide engineered with hydrolyzable ethylcarbonate side chains
Sabah Kasmi
Benoit Louage
Lutz Nuhn
Alexandra Van Driessche
Jan Van Deun
Izet Karalic
Martijn Risseeuw
Serge Van Calenbergh
Richard Hoogenboom
Riet De Rycke
et al.
A1
Journal Article
in
BIOMACROMOLECULES
2016
2015
Addition of NaCl upregulates NFAT5 expression in Duchenne muscular dystrophy cultured myotubes
Laurens Weynants
Eline Nys
Sandrine Herbelet
Boel De Paepe
Elly De Vlieghere
Liselot Mus
Lynn Feys
Olivier De Wever
Jan De Bleecker
C3
Conference
2015
An open data ecosystem for cell migration research
Paola Masuzzo
Lennart Martens
the 2014 Cell Migration workshop participants
Christophe Ampe
Olivier De Wever
Marleen Van Troys
Editorial material
2015
Biological properties of extracellular vesicles and their physiological functions
María Yáñez-Mó
Pia R-M Siljander
Zoraida Andreu
Apolonija Bedina Zavec
Francesc E Borràs
Edit I Buzas
Krisztina Buzas
Enriqueta Casal
Francesco Cappello
Joana Carvalho
et al.
A2
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2015
Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics
Elly De Vlieghere
Laurine Verset
Pieter Demetter
Marc Bracke
Olivier De Wever
A1
Journal Article
in
VIRCHOWS ARCHIV
2015
Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer
Joke Tommelein
Laurine Verset
Tom Boterberg
Pieter Demetter
Marc Bracke
Olivier De Wever
A1
Journal Article
in
FRONTIERS IN ONCOLOGY
2015
Chick heart invasion assay for testing the invasiveness of cancer cells and the activity of potentially anti-invasive compounds
Marc Bracke
Bart Roman
Christian Stevens
Liselot Mus
Virinder Parmar
Olivier De Wever
Marcus Mareel
A1
Journal Article
in
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
2015
Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells
Ijeoma Adaku Umelo
Olivier De Wever
Peter Kronenberger
Alfiah Noor
Erik Teugels
Gang Chen
Marc Bracke
Jacques De Grève
A1
Journal Article
in
LUNG CANCER
2015
Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade
Ijeoma Adaku Umelo
Olivier De Wever
Peter Kronenberger
Jan Van Deun
Alfiah Noor
Kshitiz Singh
Erik Teugels
Gang Chen
Marc Bracke
Jacques De Grève
A1
Journal Article
in
ONCOTARGET
2015
Communication of quorum sensing peptides with breast cancer cells
Frederick Verbeke
Evelien Wynendaele
Marianne Lauwers
An Hendrix
Christian Paul G. Burvenich
Olivier De Wever
marc bracke
Bart De Spiegeleer
C3
Conference
2015
Crosstalk between the microbiome and cancer cells by quorum sensing peptides
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Olivier De Wever
marc bracke
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2015
Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers
Elly De Vlieghere
Charlotte Carlier
Wim Ceelen
Marc Bracke
Olivier De Wever
A2
Journal Article
in
DATA IN BRIEF
2015
Effect of Cx-mimetic peptide administration on breast cancer brain metastasis development: a preclinical serial MRI study
Valerie De Meulenaere
Elke Decrock
Sara Neyt
Olivier De Wever
Filip De Vos
Christian Vanhove
Hannelore Denys
Benedicte Descamps
Karel Deblaere
C3
Conference
2015
Effect of GAP27 on breast cancer brain metastasis development: initial results
Valerie De Meulenaere
Elke Decrock
Sara Neyt
Olivier De Wever
Filip De Vos
Christian Vanhove
Hannelore Denys
Benedicte Descamps
Karel Deblaere
C3
Conference
2015
ETV5 functionally connect ALK and RET signaling in neuroblastoma
Irina Lambertz
Shana Claeys
Candy Kumps
Liselot Mus
Anneleen Beckers
Els Janssens
Nadine Van Roy
Genevieve Laureys
Johannes Schulte
Olivier De Wever
et al.
C3
Conference
2015
Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations
MM Koczorowska
S Tholen
F Bucher
L Lutz
JN Kizhakkedathu
Olivier De Wever
UF Wellner
ML Biniossek
A Stahl
S Lassmann
et al.
A1
Journal Article
in
MOLECULAR ONCOLOGY
2015
Fibroblast-induced matrix remodeling paves the path for invasion
Mieke Van Bockstal
Louis Libbrecht
Olivier De Wever
A1
Journal Article
in
CELL CYCLE
2015
Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer
Ijeoma Umelo
Amir Noeparest
Gang Chen
Marleen Renard
Caroline Geers
Johan Van Steenkiste
Philippe Giron
Olivier De Wever
Erik Teugels
Jacques De Grève
A1
Journal Article
in
ONCOTARGET
2015
Impact of neoadjuvant therapy on cancer-associated fibroblasts in rectal cancer
Laurine Verset
Joke Tommelein
Xavier Moles Lopez
Christine Decaestecker
Tom Boterberg
Elly De Vlieghere
Isabelle Salmon
Marcus Mareel
Marc Bracke
Olivier De Wever
et al.
A1
Journal Article
in
RADIOTHERAPY AND ONCOLOGY
2015
Inflammatory- and NaCl-induced expression of NFAT5 in muscle cells point to common stress response mechanisms
Sandrine Herbelet
Karsten Schmidt
Jana Zschüntzsch
Eline Nys
Laurens Weynants
Boel De Paepe
Olivier De Wever
Jan De Bleecker
Jens Schmidt
C3
Conference
2015
Is intraductal inoculation of tumour cells a more relevant in vivo model for immune-competent breast cancer metastasis than the classical fat pad model?
Koen Breyne
Sofie Denies
Jonas Steenbrugge
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Niek Sanders
Evelyne Meyer
C3
Conference
2015
Modulation of exosome release by cancer cells: a screening of potential inhibitors
Gertjan Rasschaert
An Hendrix
Olivier De Wever
C3
Conference
2015
Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results
Valerie De Meulenaere
Benedicte Descamps
Sara Neyt
Elke Decrock
Olivier De Wever
Filip De Vos
Christian Vanhove
Karel Deblaere
C3
Conference
2015
Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results
Valerie De Meulenaere
Benedicte Descamps
Sara Neyt
Olivier De Wever
Elke Decrock
Filip De Vos
Christian Vanhove
Karel Deblaere
C3
Conference
2015
Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results
Valerie De Meulenaere
Benedicte Descamps
Sara Neyt
Olivier De Wever
Elke Decrock
Filip De Vos
Christian Vanhove
Karel Deblaere
C3
Conference
2015
NFAT5 forms aggregates in normal and Duchenne muscular dystrophy cultured myotubes after exposure to cell stressors
Sandrine Herbelet
Ilse Beck
Zuzanna Drebert
Olivier De Wever
Jan De Bleecker
C3
Conference
2015
Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model
Félix Gremonprez
Benedicte Descamps
Andrei Izmer
Christian Vanhove
Frank Vanhaecke
Olivier De Wever
Wim Ceelen
A1
Journal Article
in
ONCOTARGET
2015
Pro-inflammatory cell stress in muscle cells is directed by NFAT5
Sandrine Herbelet
Jens Schmidt
Olivier De Wever
Eline Nys
Laurens Weynants
Dorien Clarisse
Glenn Vergauwen
Boel De Paepe
Jan De Bleecker
C3
Conference
2015
Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling
Lynn Feys
Benedicte Descamps
Christian Vanhove
Anne Vral
Liv Veldeman
Stefan Vermeulen
Carlos De Wagter
Marc Bracke
Olivier De Wever
A1
Journal Article
in
ONCOTARGET
2015
Stromal protein expression in breast cancer is differentially regulated by TGF-β1
Mieke Van Bockstal
Kathleen Lambein
Mireille Van Gele
Elly De Vlieghere
Ridha Limame
Geert Braems
marc bracke
Hannelore Denys
Louis Libbrecht
Olivier De Wever
C3
Conference
2015
The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro
Bart De Spiegeleer
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Olivier De Wever
marc bracke
Evelien Wynendaele
A1
Journal Article
in
PLOS ONE
2015
The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia
Julia D Knopf
Stefan Tholen
Maria M Koczorowska
Olivier De Wever
Martin L Biniossek
Oliver Schilling
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
2015
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
Elly De Vlieghere
Félix Gremonprez
Laurine Verset
Lore Mariën
Christopher Jones
Bram De Craene
Geert Berx
Benedicte Descamps
Christian Vanhove
Jean Paul Remon
et al.
A1
Journal Article
in
BIOMATERIALS
2015
When fat becomes an ally of the enemy : adipose tissue as collaborator in human breast cancer
Lore Lapeire
Hannelore Denys
Veronique Cocquyt
Olivier De Wever
A2
Journal Article
in
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION
2015
When the fat (lady) starts to sing : the role of adipose tissue secreted factors in breast cancer progression
Lore Lapeire
Veronique Cocquyt
Olivier De Wever
Dissertation
2015
2014
Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice
Sandra Dupouy
Van Kien Doan
Zherui Wu
Najat Mourra
Jin Liu
Olivier De Wever
Frédérique Penault Llorca
Anne Cayre
Amal Kouchkar
Anne Gompel
et al.
A1
Journal Article
in
ONCOTARGET
2014
Bio-hybrid tumor cell-templated capsules: a generic formulation strategy for tumor associated antigens in view of immune therapy
Lien Lybaert
Elly De Vlieghere
Riet De Rycke
Nane Vanparijs
Olivier De Wever
Stefaan De Koker
Bruno De Geest
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2014
Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells
Jinheng Wang
An Hendrix
Sophie Hernot
Miguel Lemaire
Elke De Bruyne
Els Van Valckenborgh
Tony Lahoutte
Olivier De Wever
Karin Vanderkerken
Eline Menu
A1
Journal Article
in
BLOOD
2014
Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling
Lore Lapeire
An Hendrix
Kathleen Lambein
Mieke Van Bockstal
Geert Braems
Rudy Van den Broecke
RIDHA LIMAME
Pieter Mestdagh
Jo Vandesompele
Christian Vanhove
et al.
A1
Journal Article
in
CANCER RESEARCH
2014
Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling
Lore Lapeire
An Hendrix
Kathleen Lambein
Mieke Van Bockstal
Geert Braems
Rudy Van den Broecke
Ridha Limame
Pieter Mestdagh
Jo Vandesompele
Christian Vanhove
et al.
C3
Conference
2014
Carcinoma-associated fibroblasts provide operational flexibility in metastasis
Olivier De Wever
Mieke Van Bockstal
Marcus Mareel
An Hendrix
Marc Bracke
A1
Journal Article
in
SEMINARS IN CANCER BIOLOGY
2014
Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Olivier De Wever
marc bracke
Bart De Spiegeleer
C3
Conference
2014
Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion
Mieke Van Bockstal
Kathleen Lambein
Mireille Van Gele
Elly De Vlieghere
RIDHA LIMAME
Geert Braems
Rudy Van den Broecke
Veronique Cocquyt
Hannelore Denys
marc bracke
et al.
A2
Journal Article
in
ONCOSCIENCE
2014
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer
RIDHA LIMAME
Ken Op de Beeck
Steven Van Laere
Lieselot Croes
Annemieke De Wilde
Luc Dirix
Guy Van Camp
Marc Peeters
Olivier De Wever
Filip Lardon
et al.
A2
Journal Article
in
ONCOSCIENCE
2014
Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype
Mieke Van Bockstal
Kathleen Lambein
Hannelore Denys
Geert Braems
ANN NUYTS
Rudy Van den Broecke
Veronique Cocquyt
Olivier De Wever
Louis Libbrecht
A1
Journal Article
in
VIRCHOWS ARCHIV
2014
How does the human microbiome affect cancer outcome?
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Olivier De Wever
marc bracke
Bart De Spiegeleer
C3
Conference
2014
JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma
A Bouchekioua
L Scourzic
Olivier De Wever
Y Zhang
P Cervera
A Aline-Fardin
T Mercher
P Gaulard
R Nyga
D Jeziorowska
et al.
A1
Journal Article
in
LEUKEMIA
2014
Krüppel-like factors in cancer progression: three fingers on the steering wheel
RIDHA LIMAME
Ken Op de Beeck
Filip Lardon
Olivier De Wever
Patrick Pauwels
A1
Journal Article
in
ONCOTARGET
2014
Mesenchymal stem cell secreted platelet derived growth factor exerts a pro-migratory effect on resident Cardiac Atrial appendage Stem Cells
Severina Windmolders
Astrid De Boeck
Remco Koninckx
Annick Daniëls
Olivier De Wever
Marc Bracke
Marc Hendrikx
Karen Hensen
Jean-Luc Rummens
A1
Journal Article
in
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
2014
Micro-particle encapsulated carcinoma-associated fibroblast (CAF) deceive and redirect disseminated cancer cells
Elly De Vlieghere
Laurine Verset
Christian Vanhove
Lore Mariën
Jean Paul Remon
Pieter Demetter
Marc Bracke
Bruno De Geest
Olivier De Wever
C3
Conference
2014
Modifications of cell signalling and redox balance by targeting protein acetylation using natural and engineered molecules: implications in cancer therapy
Kavya Venkateswaran
Amit Verma
Anant N Bhatt
Paban K Agrawala
Hanumantharao G Raj
Shashwat Malhotra
Ashok K Prasad
Olivier De Wever
Marc Bracke
Luciano Saso
et al.
A1
Journal Article
in
CURRENT TOPICS IN MEDICINAL CHEMISTRY
2014
Molecular MRI in preclinical research
Benedicte Descamps
Sara Neyt
Filip De Vos
Valerie De Meulenaere
Elke Decrock
Julie Bolcaen
Ingeborg Goethals
Olivier De Wever
Tom Boterberg
Karel Deblaere
et al.
C3
Conference
2014
Molecular MRI in preclinical research
Benedicte Descamps
Sara Neyt
Filip De Vos
Valerie De Meulenaere
Elke Decrock
Julie Bolcaen
Ingeborg Goethals
Olivier De Wever
Tom Boterberg
Karel Deblaere
et al.
C3
Conference
2014
Quorum sensing peptides: missing link between microbiome and health?
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Olivier De Wever
marc bracke
Bart De Spiegeleer
C3
Conference
2014
Screening of inhibitors for modulation of exosome release by cancer cells
Gertjan Rasschaert
An Hendrix
Olivier De Wever
C3
Conference
2014
Single cell and spheroid collagen type I invasion assay
Olivier De Wever
An Hendrix
Astrid De Boeck
Frank Eertmans
Wendy Westbroek
Geert Braems
Marc Bracke
Bookchapter
in
Metastasis research protocols
2014
Six-weeks follow-up of developing metastases in the rat brain: preliminary results of a multi-modal imaging approach
Valerie De Meulenaere
Benedicte Descamps
Sara Neyt
Olivier De Wever
Filip De Vos
Christian Vanhove
Karel Deblaere
C3
Conference
2014
Stromal characteristics are potential prognostic markers for ipsilateral locoregional recurrence in ductal carcinoma in situ (DCIS)
Mieke Van Bockstal
Kathleen Lambein
Olivier De Wever
Marleen Praet
Veronique Cocquyt
Rudy Van den Broecke
Geert Braems
Hannelore Denys
Louis Libbrecht
C3
Conference
2014
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Jan Van Deun
Pieter Mestdagh
Raija Sormunen
Lotte Pyfferoen
Karim Vermaelen
Veronique Cocquyt
Jo Vandesompele
Marc Bracke
Olivier De Wever
An Hendrix
C3
Conference
2014
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Jan Van Deun
Pieter Mestdagh
Raija Sormunen
Veronique Cocquyt
Karim Vermaelen
Jo Vandesompele
Marc Bracke
Olivier De Wever
An Hendrix
A2
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2014
2013
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis
Katrien Van Impe
Jonas Bethuyne
Steven Cool
Francis Impens
David Ruano-Gallego
Olivier De Wever
Berlinda Vanloo
Marleen Van Troys
Kathleen Lambein
Ciska Boucherie
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH
2013
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
Astrid De Boeck
Patrick Pauwels
Karen Hensen
Jean-Luc Rummens
Wendy Westbroek
An Hendrix
Dawn Maynard
Hannelore Denys
Kathleen Lambein
Geert Braems
et al.
A1
Journal Article
in
GUT
2013
CAF-encapsulated mico-particels capture free cancer cells from the peritoneal fluid
Elly De Vlieghere
Laurine Verset
Christian Vanhove
Lore Mariën
Jean Paul Remon
Pieter Demetter
Marc Bracke
Bruno De Geest
Olivier De Wever
C3
Conference
2013
Development of a new highly specific targeting probe for non-invasive in vivo visualization of Ncadherin expression in prostate cancer
Christian Vanhove
Caroline Dumolyn
Piet Ost
Olivier De Wever
Filip De Vos
C3
Conference
2013
Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression
Astrid De Boeck
An Hendrix
Dawn Maynard
Mieke Van Bockstal
Annick Daniëls
Patrick Pauwels
Christian Gespach
Marc Bracke
Olivier De Wever
A1
Journal Article
in
PROTEOMICS
2013
Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer
L Verset
Joke Tommelein
X Moles Lopez
Carolien Decaestecker
Marcus Mareel
Marc Bracke
Ilse Salmon
Olivier De Wever
P Demetter
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2013
miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells
Peter Dynoodt
Reinhart Speeckaert
Olivier De Wever
INES CHEVOLET
Lieve Brochez
Jo Lambert
Mireille Van Gele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
2013
Protein secretome analysis of evolving and responding tumor ecosystems
Olivier De Wever
Astrid De Boeck
Dawn Maynard
Marc Bracke
An Hendrix
A1
Journal Article
in
CURRENT PROTEOMICS
2013
Rab27 GTPases distribute extracellular nanomaps for invasive growth and metastasis: implications for prognosis and treatment
An Hendrix
Olivier De Wever
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2013
Rab27B-mediated metabolic reprogramming induces secretome acidification and chemoresistance in breast cancer cells
An Hendrix
Carla Ciccone
Christian Gespach
Marc Bracke
Olivier De Wever
Wendy Westbroek
A2
Journal Article
in
EXOSOMES AND MICROVESICLES
2013
Radiation-induced myosin IIA expression stimulates collagen type I matrix reorganization
Stéphanie Blockhuys
Bart Van Rompaye
Riet De Rycke
Kathleen Lambein
Kathleen Claes
Marc Bracke
Carlos De Wagter
Olivier De Wever
A1
Journal Article
in
RADIOTHERAPY AND ONCOLOGY
2013
Stromal architecture and periductal decorin are potential prognostic markers for ipsilateral locoregional recurrence in ductal carcinoma in situ of the breast
Mieke Van Bockstal
Kathleen Lambein
Olivier Gevaert
Olivier De Wever
Marleen Praet
Veronique Cocquyt
Rudy Van den Broecke
Geert Braems
Hannelore Denys
Louis Libbrecht
A1
Journal Article
in
HISTOPATHOLOGY
2013
Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery
Bart Geers
Olivier De Wever
Jo Demeester
Marc Bracke
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
SMALL
2013
Tenascin-C downregulates Wnt inhibitor Dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model
Falk Saupe
Anja Schwenzer
Yundan Jia
Isabelle Gasser
Caroline Spenlé
Benoit Langlois
Martial Kammerer
Olivier Lefebvre
Ruslan Hlushchuk
Tristan Rupp
et al.
A1
Journal Article
in
CELL REPORTS
2013
The in ovo CAM-assay as a xenograft model for sarcoma
Gwen Sys
Lore Lapeire
Nikita Stevens
Herman Favoreel
Ramses Forsyth
Marc Bracke
Olivier De Wever
A1
Journal Article
in
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
2013
Tunable self-assembled nanogels composed of well-defined thermoresponsive hyaluronic acid-polymer conjugates
Jing Jing
David Alaimo
Elly De Vlieghere
Christine Jérôme
Olivier De Wever
Bruno De Geest
Rachel Auzély-Velty
A1
Journal Article
in
JOURNAL OF MATERIALS CHEMISTRY B
2013
Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer
An Hendrix
Raija Sormunen
Wendy Westbroek
Kathleen Lambein
Hannelore Denys
Gwen Sys
Geert Braems
Rudy Van den Broecke
Veronique Cocquyt
Christian Gespach
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2013
2012
An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue
An Hendrix
Kathleen Lambein
Wendy Westbroeck
Miguel C Seabra
Veronique Cocquyt
Patrick Pauwels
Marc Bracke
Christian Gespach
Olivier De Wever
A1
Journal Article
in
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
2012
Bone marrow-derived mesenchymal stem cells in colorectal cancer: NRG at the invasion front
Astrid De Boeck
Marc Bracke
Olivier De Wever
Dissertation
2012
Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays
Ridha Limame
An Wouters
Bea Pauwels
Erik Fransen
Marc Peeters
Filip Lardon
Olivier De Wever
Patrick Pauwels
A1
Journal Article
in
PLOS ONE
2012
Engineered (hep/pARG)2 polyelectrolyte capsules for sustained release of bioactive TGF-β1
Liesbeth De Cock
Olivier De Wever
Sandra Van Vlierberghe
Els Vanderleyden
Peter Dubruel
Filip De Vos
Chris Vervaet
Jean Paul Remon
Bruno De Geest
A1
Journal Article
in
SOFT MATTER
2012
Engineered 3D microporous gelatin scaffolds to study cell migration
Liesbeth De Cock
Olivier De Wever
Hamida Hammad
Bart Lambrecht
Els Vanderleyden
Peter Dubruel
Filip De Vos
Chris Vervaet
Jean Paul Remon
Bruno De Geest
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2012
Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchyinal transition
Radia Ouelaa-Benslama
Olivier De Wever
An Hendrix
Michèle Sabbah
Kathleen Lambein
David Land
Grégoire Prévost
Marc Bracke
Mien-Chie Hung
Annette K Larsen
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
2012
Multi-targeting the ERBB receptors may overcome EGFR-T790M-mediated resistance to tyrosine kinase inhibitors
IA Umelo
Olivier De Wever
E Teugels
G Chen
marc bracke
J de Greve
C3
Conference
2012
Rab27B, an ex(o)citing driver of breast cancer growth, invasion and metastasis
An Hendrix
Wendy Westbroek
Marc Bracke
Olivier De Wever
C3
Conference
2012
Recent developments in myofibroblast biology paradigms for connective tissue remodeling
Boris Hinz
Sem H Phan
Victor J Thannickal
Marco Prunotto
Alexis Desmouliere
John Varga
Olivier De Wever
Marcus Mareel
Giulio Gabbian
A1
Journal Article
in
AMERICAN JOURNAL OF PATHOLOGY
2012
Tumor grafts derived from sarcoma patients retain tumor morphology, viability, and invasion potential and indicate disease outcomes in the chick chorioallantoic membrane model
Gwen Sys
Mieke Van Bockstal
Ramses Forsyth
Maurice Balke
Bart Poffyn
Dirk Uyttendaele
Marc Bracke
Olivier De Wever
A1
Journal Article
in
CANCER LETTERS
2012
2011
Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression
Lore Lapeire
An Hendrix
Kathleen Lambein
Geert Braems
P Valet
Rudy Van den Broecke
Marc Bracke
Veronique Cocquyt
Hannelore Denys
Olivier De Wever
C3
Conference
2011
CCN5, a novel transcriptional repressor of the transforming growth factor beta signaling pathway
Michèle Sabbah
Céline Prunier
Nathalie Ferrand
Virginie Megalophonos
Kathleen Lambein
Olivier De Wever
Nicolas Nazaret
Joël Lachuer
Sylvie Dumont
Gérard Redeuilh
A1
Journal Article
in
MOLECULAR AND CELLULAR BIOLOGY
2011
Developmental and cancer research on the mammary gland nowadays: preface
Marc Bracke
Olivier De Wever
Editorial material
2011
Experimental procedures to assay invasion-associated activities of primary cultured fibroblasts
An Hendrix
Koen Jacobs
Astrid De Boeck
Wendy Westbroeck
Marc Bracke
Olivier De Wever
Bookchapter
in
Mouse as a model organism : from animal to cells
2011
Invasie en metastasering
Marc Bracke
Olivier De Wever
Luc Vakaet
Bookchapter
in
Kanker biomedisch bekeken
2011
Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts
Olivier De Wever
Joëlle Sobczak-Thépot
Anne-Sophie Vercoutter-Edouart
Jean-Claude Michalski
Radia Ouelaa-Benslama
Dwayne G Stupack
Marc Bracke
Jean YJ Wang
christian Gespach
Shahin Emami
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
2011
Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?
An Hendrix
Marc Bracke
Olivier De Wever
A2
Journal Article
in
ONCO (NEDERLANDSE ED.)
2011
Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?
An Hendrix
Marc Bracke
Olivier De Wever
A4
Journal Article
in
GUNAÏKEIA (NEDERLANDSE EDITIE)
2011
Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis
Soraya Sin
Florian Bonin
Valérie Petit
Didier Meseure
François Lallemand
Ivan Bièche
Akeila Bellahcène
Vincent Castronovo
Olivier De Wever
Christian Gespach
et al.
A1
Journal Article
in
JOURNAL OF THE NATIONAL CANCER INSTITUTE
2011
Signaling networks in cancer: an interview with Christian Gespach
Olivier De Wever
Editorial material
2011
The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells
Lara Derycke
Christophe Stove
Anne-Sophie Vercoutter-Edouart
Olivier De Wever
Laurent Dollé
Nathalie Colpaert
Herman Depypere
Jean-Claude Michalski
Marc Bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
2011
The tumor ecosystem regulates the roads for invasion and metastasis
An Hendrix
Christian Gespach
Marc Bracke
Olivier De Wever
A1
Journal Article
in
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
2011
Use of tamoxifen before and during pregnancy
Geert Braems
Hannelore Denys
Olivier De Wever
Veronique Cocquyt
Rudy Van den Broecke
A1
Journal Article
in
ONCOLOGIST
2011
2010
An ex(o)citing machinery for invasive tumor growth
An Hendrix
Wendy Westbroek
Marc Bracke
Olivier De Wever
A1
Journal Article
in
CANCER RESEARCH
2010
Cellular and molecular mechanisms of cancer cell invasion
Olivier De Wever
Lore Lapeire
Astrid De Boeck
An Hendrix
A4
Journal Article
in
VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË
2010
Direct Effects of Delta Opioid Receptor Agonists on Invasion-associated Activities of HCT-8/E11 Colon Cancer Cells
Delphine Debruyne
A Leroy
Olivier De Wever
Luc Vakaet
Marcus Mareel
Marc Bracke
A1
Journal Article
in
ANTICANCER RESEARCH
2010
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis
An Hendrix
Dawn Maynard
Patrick Pauwels
Geert Braems
Hannelore Denys
Rudy Van den Broecke
Jo Lambert
Simon Van Belle
Veronique Cocquyt
Christian Gespach
et al.
A1
Journal Article
in
JOURNAL OF THE NATIONAL CANCER INSTITUTE
2010
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells
Mathieu Boissan
Olivier De Wever
Floria Lizarraga
Dominique Wendum
Renaud Poincloux
Nicolas Chignard
Christele Desbois-Mouthon
Sylvie Dufour
Beatrice Nawrocki-Raby
Philippe Birembaut
et al.
A1
Journal Article
in
CANCER RESEARCH
2010
Modeling and quantification of cancer cell invasion through collagen type I matrices
Olivier De Wever
An Hendrix
Astrid De Boeck
Wendy Westbroek
Geert Braems
Shahin Emami
Michèle Sabbah
Christian Gespach
Marc Bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
2010
P-cadherin counteracts myosin II-B function : implications in melanoma progression
Koen Jacobs
Mireille Van Gele
Ramses Forsyth
Lieve Brochez
Barbara Vanhoecke
Olivier De Wever
Marc Bracke
A1
Journal Article
in
MOLECULAR CANCER
2010
Resident and bone marrow-derived mesenchymal stem cells in head and neck squamous cell carcinoma
Astrid De Boeck
Kishan Narine
Wilfried De Neve
Marcus Mareel
Marc Bracke
Olivier De Wever
A1
Journal Article
in
ORAL ONCOLOGY
2010
The NF-κB inhibitor IκBα negates colon cancer cell migration, invasion, proliferation and tumor growth
Samir Attoub
Rabah Iratni
Suhail Al-Salam
Khouloud Arafat
MAH Al Sultan
Nadia Al Marzouqi
Eric Bruyneel
Marc Bracke
Olivier De Wever
Christian Gespach
A2
Journal Article
in
JOURNAL OF MEDICAL SCIENCES (BENTHAM)
2010
The role of myofibroblasts in communicating tumor ecosystems
Olivier De Wever
Astrid De Boeck
Pieter Demetter
Marcus Mareel
Marc Bracke
Bookchapter
in
Tumor-associated fibroblasts and their matrix
2010
The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer
An Hendrix
Hannelore Denys
Geert Braems
Patrick Pauwels
Rudy Van den Broecke
Veronique Cocquyt
Wendy Westbroek
marc bracke
Olivier De Wever
C3
Conference
2010
The secretory small GTPase Rab27B as a marker for breast cancer progression
An Hendrix
Geert Braems
Marc Bracke
Miguel C Seabra
William A Gahl
Olivier De Wever
Wendy Westbroek
A1
Journal Article
in
ONCOTARGET
2010
2009
Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on G alpha Subunit
MA Ayoub
M Damian
C Gespach
E Ferrandis
O Lavergne
Olivier De Wever
JL Baneres
JP Pin
GP Prevost
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2009
The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment
Hannelore Denys
Geert Braems
Kathleen Lambein
Patrick Pauwels
An Hendrix
Astrid De Boeck
Veronique Mathieu
Marc Bracke
Olivier De Wever
A1
Journal Article
in
CURRENT PHARMACEUTICAL DESIGN
2009
The myofibroblast, electron microscopy and cancer research: reply
Olivier De Wever
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2009
The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha
An Hendrix
D Maynard
P Pauwels
G Braems
Hannelore Denys
Rudy Van den Broecke
Simon Van Belle
Veronique Cocquyt
marc bracke
M Seabra
et al.
C3
Conference
2009
2008
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome
Wendy Westbroek
M TUCHMAN
B TINLOY
Olivier De Wever
T VILBOUX
JM HERTZ
H HASLE
C HEILMANN
A HELIP-WOOLEY
R KLETA
et al.
A1
Journal Article
in
MOLECULAR GENETICS AND METABOLISM
2008
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells
V GOUYER
D FONTAINE
Pieter Dumont
Olivier De Wever
H FONTAYNE-DEVAUD
E LETEURTRE
S TRUANT
D DELACOUR
H DROBECQ
JP KERCKAERT
et al.
A1
Journal Article
in
ONCOGENE
2008
Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion
Hannelore Denys
Lara Derycke
An Hendrix
Wendy Westbroek
Alexander Gheldof
Kishan Narine
Patrick Pauwels
Christian Gespach
Marc Bracke
Olivier De Wever
A1
Journal Article
in
CANCER LETTERS
2008
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front
Olivier De Wever
Patrick Pauwels
Bram De Craene
M SABBAH
S EMAMI
G REDEUILH
C GESPACH
marc bracke
Geert Berx
A1
Journal Article
in
HISTOCHEMISTRY AND CELL BIOLOGY
2008
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
Michele Sabbah
Shahin Emami
Gerard Redeuilh
Sylvia Julien
Gregoire Prevost
Amazia Zimber
Radia Ouelaa
Marc Bracke
Olivier De Wever
Christian Gespach
A1
Journal Article
in
DRUG RESISTANCE UPDATES
2008
Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73 alpha tumor suppressor
Jean-Pierre Roperch
Karima El Quadrani
An Hendrix
Shabin Emami
Olivier De Wever
Gerry Melina
Christian Gespach
A1
Journal Article
in
Cancer Research
2008
Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells
A FRITAH
C SAUCIER
Olivier De Wever
marc bracke
I BIECHE
R LIDEREAU
C GESPACH
S DROUOT
G REDEUILH
M SABBAH
A1
Journal Article
in
MOLECULAR AND CELLULAR BIOLOGY
2008
Stromal myofibroblasts are drivers of invasive cancer growth
Olivier De Wever
Pieter Demetter
Marcus Mareel
Marc Bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2008
The Transforming Functions of PI3-kinase-gamma Are Linked to Disruption of Intercellular Adhesion and Promotion of Cancer Cell Invasion
Samir Attoub
Olivier De Wever
Eric Bruyneel
Marcus Mareel
Christian Gespach
A1
Journal Article
in
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
2008
2007
Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha 1-integrins during colon cancer cell invasion
SABINE VAN SLAMBROUCK
C GRIJELMO
Olivier De Wever
Erik Bruyneel
S EMAMI
C GESPACH
Wim Steelant
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
2007
Akt1 & 2 depletion by RNA interference reduced tumor growth and invasion in human colon cancer cells
A GABON
Olivier De Wever
Erik Bruyneel
marc bracke
C GESPACH
S ATTOUB
C3
Conference
2007
Cell motility and breast cancer metastasis.
Marc Bracke
Daan De Maeseneer
Veerle Van Marck
Lara Derycke
Barbara Vanhoecke
Olivier De Wever
Herman Depypere
Bookchapter
in
Metastasis of Breast Cancer.
2007
Estrogen receptor alpha (ER alpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alpha T3-1 cell line
F Eertmans
Willem Dhooge
Olivier De Wever
marc bracke
Frank Comhaire
Jean Kaufman
A1
Journal Article
in
JOURNAL OF CELLULAR PHYSIOLOGY
2007
Estrogen receptor signaling is an unstable feature of the gonadotropic LβT2 cell line
F Eertmans
Willem Dhooge
Olivier De Wever
Wim Vanden Berghe
Veerle Bogaert
Marc Bracke
Guy Haegeman
Frank Comhaire
Jean Kaufman
A1
Journal Article
in
MOLECULAR AND CELLULAR ENDOCRINOLOGY
2007
Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis
S RODRIGUES
Olivier De Wever
Erik Bruyneel
RJ ROONEY
C GESPACH
A1
Journal Article
in
ONCOGENE
2007
Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac JNK-dependent signaling pathways in colon cancer cells
C GRIJELMO
C RODRIGUE
M SVRCEK
Erik Bruyneel
An Hendrix
Olivier De Wever
C GESPACH
A1
Journal Article
in
CELLULAR SIGNALLING
2007
Soluble cadherins as cancer biomarkers
Olivier De Wever
Lara Derycke
An Hendrix
Gert De Meerleer
F GODEAU
Herman Depypere
marc bracke
A1
Journal Article
in
CLINICAL & EXPERIMENTAL METASTASIS
2007
The tandem PDZ domains of syntenin promote cell invasion
Kris Meerschaert
Erik Bruyneel
Olivier De Wever
Berlinda Vanloo
Ciska Boucherie
marc bracke
Joël Vandekerckhove
Jan Gettemans
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2007
2006
Growth factor modulation of fibroblast proliferation, differentiation, and invasion: Implications for tissue valve engineering
K NARINE
Olivier De Wever
Dillis Van Valckenborgh
Katrien Francois
marc bracke
Stefaan De Smet
Marcus Mareel
Guido Van Nooten
A1
Journal Article
in
TISSUE ENGINEERING
2006
Pro-invasive molecular cross-signaling between cancer cells and myofibroblasts
Olivier De Wever
Marcus Mareel
Bookchapter
in
Tissue repair, contraction and the myofibroblast
2006
Role of adipocyte-derived resistin in breast cancer
Dillis Van Valckenborgh
Olivier De Wever
An Hendrix
M BRACKE
R VANDENBROECKE
Simon Van Belle
P PAUWELS
Veronique Cocquyt
HANNELORE DENYS
C3
Conference
2006
Soluble N-cadherin fragment promotes angiogenesis
Lara Derycke
L MORBIDELLI
M ZICHE
Olivier De Wever
marc bracke
Elisabeth Van Aken
A1
Journal Article
in
CLINICAL & EXPERIMENTAL METASTASIS
2006
Soluble N-cadherin in human biological fluids
Lara Derycke
Olivier De Wever
Veronique Stove
Barbara Vanhoecke
Joris Delanghe
Herman Depypere
marc bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2006
2005
Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment
QD NGUYEN
Olivier De Wever
Erik Bruyneel
An Hendrix
WZ XIE
A LOMBET
M LEIBL
Marcus Mareel
F GIESELER
marc bracke
et al.
A1
Journal Article
in
ONCOGENE
2005
2004
A road map for cancer invasion : implication of myofibroblasts and other factors
Olivier De Wever
Marc Bracke
Marcus Mareel
Dissertation
2004
Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding
Olivier De Wever
Wendy Westbroek
A VERLOES
N BLOEMEN
marc bracke
C GESPACH
Erik Bruyneel
Marcus Mareel
A1
Journal Article
in
JOURNAL OF CELL SCIENCE
2004
Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes
C RIVAT
Olivier De Wever
Erik Bruyneel
Marcus Mareel
C GESPACH
S ATTOUB
A1
Journal Article
in
ONCOGENE
2004
Germinal tumor invasion and the role of the testicular stroma
A DIEZ-TORRE
U SILVAN
Olivier De Wever
Erik Bruyneel
Marcus Mareel
J ARECHAGA
A1
Journal Article
in
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
2004
Invasion and MMP expression profile in desmoid tumours
H DENYS
Olivier De Wever
B NUSGENS
Y KONG
R SCIOT
AT LE
K VAN DAM
A JADIDIZADEH
S TEJPAR
Marcus Mareel
et al.
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2004
Mutated E-cadherin: Genomic and functional characterization in thyroid cells from the KAT family
AS ROCHA
Olivier De Wever
S MOREIRA
MJ COSTA
Joël Vandekerckhove
Marcus Mareel
P SOARES
A1
Journal Article
in
THYROID
2004
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent proinvasive signals to human colon cancer cells through RhoA and Rac
Olivier De Wever
QD NGUYEN
Leen Van Hoorde
marc bracke
Erik Bruyneel
C GESPACH
Marcus Mareel
A1
Journal Article
in
FASEB JOURNAL
2004
The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3β and c-Jun/AP-1 signaling
Nathalie Le Floch
Christine Rivat
Olivier De Wever
Erik Bruyneel
Marcus Mareel
Trevor Dale
Christian Gespach
A1
Journal Article
in
FASEB JOURNAL
2004
2003
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands
G SURIANO
C OLIVEIRA
P FERREIRA
JC MACHADO
MC BORDIN
Olivier De Wever
Erik Bruyneel
N MOGUILEVSKY
N GREHAN
TR PORTER
et al.
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2003
Invasion of retinal pigment epithelial cells: N-cadherin, hepatocyte growth factor, and focal adhesion kinase
Elisabeth Van Aken
Olivier De Wever
Leen Van Hoorde
Erik Bruyneel
Jean Delaey
Marcus Mareel
A1
Journal Article
in
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
2003
Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells
S TRUANT
Erik Bruyneel
V GOUYER
Olivier De Wever
FR PRUVOT
Marcus Mareel
G HUET
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2003
Role of tissue stroma in cancer cell invasion
Olivier De Wever
Marcus Mareel
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2003
The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion
G SURIANO
D MULHOLLAND
Olivier De Wever
P FERREIRA
AR MATEUS
Erik Bruyneel
CC NELSON
Marcus Mareel
J YOKOTA
D HUNTSMAN
et al.
A1
Journal Article
in
ONCOGENE
2003
2002
Role of myofibroblasts at the invasion front.
Olivier De Wever
Marcus Mareel
A1
Journal Article
in
BIOLOGICAL CHEMISTRY
2002
2001
Defective E-cadherin/catenin complexes in human cancer
Elisabeth Van Aken
Olivier De Wever
ASC DA ROCHA
Marcus Mareel
A1
Journal Article
in
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
2001