Research Explorer

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Researcher

Lieven Van Meulebroek

Awards & Distinctions

85 Results

2023

Comprehensive metabolomics reveals correlation between sophorolipid biosynthesis and autophagy

Sven DierickxMaximilien SouvereynsSophie RoelantsMarilyn De GraeveLieven Van MeulebroekSofie De MaeseneireWim SoetaertLynn Vanhaecke

A1 Journal Article in NEW BIOTECHNOLOGY

Direct metabotyping of biofluids: advancing ambient metabolomics through Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry (LA-REIMS)

Vera PlekhovaLynn VanhaeckeLieven Van Meulebroek

Molecular analysis of broad-spectrum induced resistance in rice by the green leaf volatile Z-3-hexenyl acetate

Willem DesmedtMaarten AmeyeOsvaldo FilipeEvelien De WaeleFilip Van NieuwerburghDieter DeforceLieven Van MeulebroekLynn VanhaeckeTina KyndtMonica Höfte et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

2022

A comprehensive review on carotenoids in foods and feeds : status quo, applications, patents, and research needs

Antonio J. Meléndez-MartínezAnamarija I. MandićFilippos BantisVolker BöhmGrethe Iren A. BorgeMladen BrnčićAnette BystedM. Pilar CanoM. Graça DiasAnjo Elgersma et al.

A1 Journal Article in CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

A multi-omics study to boost continuous bolaform sophorolipid production

Sven DierickxKarolien MaesSophie RoelantsBeata PomianLieven Van MeulebroekSofie De MaeseneireLynn VanhaeckeWim Soetaert

A1 Journal Article in NEW BIOTECHNOLOGY

2021

An interdisciplinary-omics study to boost continuous bolaform sophorolipid production

Sven DierickxKarolien MaesSophie RoelantsLieven Van MeulebroekSofie De MaeseneireLynn VanhaeckeWim Soetaert

Comprehensive polar metabolomics and lipidomics profiling discriminates the transformed from the non-transformed state in colon tissue and cell lines

Caroline RomboutsMargot De SpiegeleerLieven Van MeulebroekLynn VanhaeckeWinnok H. De Vos

A1 Journal Article in SCIENTIFIC REPORTS

Curcumin and fish oil as natural anti-inflammatory compounds in Holstein neonatal calves : a metabolomics approach

Saeid KameloroumiehLynn VanhaeckeLieven Van Meulebroek

Effect of nanocurcumin and fish oil as natural anti-inflammatory compounds vs. glucocorticoids in a lipopolysaccharide inflammation model on Holstein calves’ health status

Saeid KameloroumiehLynn VanhaeckeR. ValizadehLieven Van MeulebroekA. A. Naserian

A1 Journal Article in HELIYON

Metabolic fingerprinting of feces from calves, subjected to gram-negative bacterial endotoxin

Saeid KameloroumiehAbbas Ali NaserianLieven Van MeulebroekEllen De PaepeReza ValizadehLynn Vanhaecke

A1 Journal Article in METABOLITES

Paediatric obesity : a systematic review and pathway mapping of metabolic alterations underlying early disease processes

Margot De SpiegeleerEllen De PaepeLieven Van MeulebroekInge GiesJean De SchepperLynn Vanhaecke

A1 Journal Article in MOLECULAR MEDICINE

Rapid ex vivo molecular fingerprinting of biofluids using laser-assisted rapid evaporative ionization mass spectrometry

Vera PlekhovaLieven Van MeulebroekMarilyn De GraeveAlvaro Perdones-MonteroMargot De SpiegeleerEllen De PaepeEmma Van de WalleZoltan TakatsSimon J. S. CameronLynn Vanhaecke

A1 Journal Article in NATURE PROTOCOLS

Sample preparation free mass spectrometry using laser-assisted rapid evaporative ionization mass spectrometry : applications to microbiology, metabolic biofluid phenotyping, and food authenticity

Simon J. S. CameronAlvaro Perdones-MonteroLieven Van MeulebroekAdam BurkeKate Alexander-HardimanDaniel SimonRichard SchafferJulia BalogTamas KarancsiTony Rickards et al.

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The bee hemolymph metabolome : a window into the impact of viruses on bumble bees

Luoluo WangLieven Van MeulebroekLynn VanhaeckeGuy SmaggheIvan Meeus

A1 Journal Article in VIRUSES-BASEL

Triangulation of microbial fingerprinting in anaerobic digestion reveals consistent fingerprinting profiles

Jo De VriezeRobert HeyerRuben PropsLieven Van MeulebroekKaren GilleLynn VanhaeckeDirk BenndorfNico Boon

A1 Journal Article in WATER RESEARCH

Untargeted metabolomics reveals elevated L‐carnitine metabolism in pig and rat colon tissue following red versus white meat intake

Caroline RomboutsLieven Van MeulebroekMargot De SpiegeleerSophie GoethalsThomas Van HeckeStefaan De SmetWinnok De VosLynn Vanhaecke

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

2020

An interdisciplinary -omics study to boost continuous bolaform sophorolipid production

Sven DierickxKarolien MaesSophie RoelantsLieven Van MeulebroekSofie De MaeseneireLynn VanhaeckeWim Soetaert

Impact of storage conditions on the human stool metabolome and lipidome : preserving the most accurate fingerprint

Margot De SpiegeleerMarilyn De GraeveSteve HuysmanArno VanderbekeLieven Van MeulebroekLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Metabolomic analysis of cricket paralysis virus infection in Drosophila S2 cells reveals divergent effects on central carbon metabolism as compared with silkworm Bm5 cells

Luoluo WangLuc SweversLieven Van MeulebroekIvan MeeusLynn VanhaeckeGuy Smagghe

A1 Journal Article in VIRUSES-BASEL

Metabolomics meets white biotechnology : interdisciplinary approaches to resolve suboptimal biosurfactant production

Sven DierickxSophie RoelantsLieven Van MeulebroekSofie De MaeseneireWim SoetaertLynn Vanhaecke

Metabolomics reveal induction of ROS production and glycosylation events in wheat upon exposure to the green leaf volatile Z-3-hexenyl acetate

Maarten AmeyeLieven Van MeulebroekBianca MeuninckLynn VanhaeckeGuy SmaggheGeert HaesaertKris Audenaert

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy

Ellen De PaepeLieven Van MeulebroekVera PlekhovaMyriam Van WinckelEric CoxLynn Vanhaecke

Rapid LA-REIMS and comprehensive UHPLC-HRMS for metabolic phenotyping of feces

Lieven Van MeulebroekSimon CameronVera PlekhovaMargot De SpiegeleerKathleen WijnantNathalie MichelsStefaan De HenauwBruno LapauwZoltan TakatsLynn Vanhaecke

A1 Journal Article in TALANTA

Untargeted metabolomics to reveal red versus white meat‐associated gut metabolites in a prudent and western dietary context

Sophie GoethalsCaroline RomboutsLieselot HemeryckLieven Van MeulebroekThomas Van HeckeEls VossenJohn Van CampStefaan De SmetLynn Vanhaecke

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Validated ultra-high-performance liquid-chromatography hybrid high-resolution mass spectrometry and laser-assisted rapid evaporative ionization mass spectrometry for salivary metabolomics

Kathleen WijnantLieven Van MeulebroekBeata PomianKimberly De WindtStefaan De HenauwNathalie MichelsLynn Vanhaecke

A1 Journal Article in ANALYTICAL CHEMISTRY

2019

A metabolomics approach to unravel cricket paralysis virus infection in silkworm Bm5 cells

Luoluo WangLuc SweversCaroline RomboutsIvan MeeusLieven Van MeulebroekLynn VanhaeckeGuy Smagghe

A1 Journal Article in VIRUSES-BASEL

Gut metabotyping of obese and overweight children towards early prevention and prognosis of metabolic diseases

Margot De SpiegeleerLieven Van MeulebroekJean De SchepperLynn Vanhaecke

Metabolomics as a tool to discover metabolite biomarkers for cow milk allergy diagnosis

Ellen De PaepeLieven Van MeulebroekEric CoxLynn Vanhaecke

Metabolomics-based biomarker discovery for bee health monitoring : a proof of concept study concerning nutritional stress in Bombus terrestris

Luoluo WangIvan MeeusCaroline RomboutsLieven Van MeulebroekLynn VanhaeckeGuy Smagghe

A1 Journal Article in SCIENTIFIC REPORTS

Multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy

Ellen De PaepeLieven Van MeulebroekVera PlekhovaMyriam Van WinckelEric CoxLynn Vanhaecke

Targeted quantification and untargeted screening of alkylphenols, bisphenol A and phthalates in aquatic matrices using ultra-high-performance liquid chromatography coupled to hybrid Q-Orbitrap mass spectrometry

Steve HuysmanLieven Van MeulebroekOlivier JanssensFrancis VanryckeghemHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Validated comprehensive metabolomics and lipidomics analysis of colon tissue and cell lines

Caroline RomboutsMargot De SpiegeleerLieven Van MeulebroekWinnok De VosLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

2018

A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography coupled to hybrid orbitrap high-resolution mass spectrometry

Ellen De PaepeLieven Van MeulebroekCaroline RomboutsSteve HuysmanKaat VerplankenBruno LapauwJella WautersLieselot HemeryckLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Comprehensive metabolomic fingerprinting discriminates cancer from the non-transformed state in colonic tissue and cell lines

Caroline RomboutsLieven Van MeulebroekWinnok De VosLynn Vanhaecke

Discovery of urinary biomarkers to discriminate between exogenous and semi-endogenous thiouracil in cattle : a parallel-like randomized design

Lieven Van MeulebroekJella WautersBeata PomianJulie Vanden BusschePhilippe DelahautEric FichantLynn Vanhaecke

A1 Journal Article in PLOS ONE

Gibberellin antagonizes jasmonate-induced defense against Meloidogyne graminicola in rice

Henok Zemene YimerKamrun NaharTina KyndtAshley HaeckLieven Van MeulebroekLynn VanhaeckeKristof DemeestereMonica HöfteGodelieve Gheysen

A1 Journal Article in NEW PHYTOLOGIST

Have plasticizers already reached our marine environment?

Steve HuysmanLieven Van MeulebroekFrancis VanryckeghemHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

Metabolites in digestive contents of pigs fed human diets : red versus white meat in the context of a prudent and western diet

Sophie GoethalsCaroline RomboutsLieselot HemeryckLieven Van MeulebroekThomas Van HeckeEls VossenJohn Van CampStefaan De SmetLynn Vanhaecke

Multi-matrix biofluid metabolomics as a promising tool for biomarker discovery and pathway analysis

Ellen De PaepeLieven Van MeulebroekLynn Vanhaecke

Nutrimetabolomics : an integrative action for metabolomic analyses in human nutritional studies

Marynka M UlaszewskaChristoph H WeinertAlessia TrimignoReto PortmannCristina Andres LacuevaRené BadertscherLorraine BrennanCarl BruniusAchim BubFrancesco Capozzi et al.

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

REIMS : enabling fast metabolomics and lipidomics without sample preparation

Arno VanderbekeLieselot HemeryckCaroline RomboutsLieven Van MeulebroekLynn Vanhaecke

The increasing prevalence of food allergies poses a huge thread to the world's wellbeing

Ellen De PaepeLieven Van MeulebroekEric CoxLynn Vanhaecke

UHPLC-HRMS based targeted and untargeted screening of plasticizers in the marine environment

Steve HuysmanLieven Van MeulebroekFrancis VanryckeghemHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

2017

A novel spiral-filter press for tomato processing : process impact on phenolic compounds, carotenoids and ascorbic acid content

Lies KipsDomien De PaepeLieven Van MeulebroekChristof Van PouckeRomain LarbatNathalie BernaertEls Van PamelMarc De LooseKatleen RaesBart Van Droogenbroeck

A1 Journal Article in JOURNAL OF FOOD ENGINEERING

A validated ultra-high performance liquid chromatography coupled to high resolution mass spectrometry multi-matrix polar metabolomics fingerprinting platform

Ellen De PaepeLieven Van MeulebroekCaroline RomboutsSteve HuysmanKaat VerplankenLieselot HemeryckJella WautersBruno LapauwLynn Vanhaecke

Development and validation of an ultra-high performance liquid chromatographic high resolution Q-Orbitrap mass spectrometric method for the simultaneous determination of steroidal endocrine disrupting compounds in aquatic matrices

Steve HuysmanLieven Van MeulebroekFrancis VanryckeghemHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Discrimination between synthetically administered and endogenous thiouracil based on monitoring of urine, muscle, and thyroid tissue : an in vivo study in young and adult bovines

Jella WautersLieven Van MeulebroekE FichantP DelahautLynn Vanhaecke

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Emerging contaminants and toxins in aquaculture : how modern analytical tools may aid to ensure food and environmental safety

Lynn VanhaeckeSteve HuysmanLieven Van Meulebroek

High resolution mass spectrometry-based screening reveals lipophilic toxins in multiple trophic levels from the North Sea

Gabriel Orellana MancillaLieven Van MeulebroekMaarten De RijckeColin JanssenLynn Vanhaecke

A1 Journal Article in HARMFUL ALGAE

Holistic lipidomics of the human gut phenotype using validated ultra-high-performance liquid chromatography coupled to hybrid orbitrap mass spectrometry

Lieven Van MeulebroekEllen De PaepeVicky VercruysseBeata PomianSimon BosBruno LapauwLynn Vanhaecke

A1 Journal Article in ANALYTICAL CHEMISTRY

Pharmacokinetic and urinary profiling reveals the prednisolone/cortisol ratio as a valid biomarker for prednisolone administration

Lieven Van MeulebroekNathalie De ClercqJulie Vanden BusscheMathias DevreeseEric FichantPhilippe DelahautSiska CroubelsLynn Vanhaecke

A1 Journal Article in BMC VETERINARY RESEARCH

Targeted, suspected and non-target screening with high resolution mass spectrometry in the marine environment : ready to go?

Steve HuysmanFrancis VanryckeghemLieven Van MeulebroekEllen De PaepeHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

The central role of modern analytical tools in studying the link between oceans & human health

Lynn VanhaeckeSteve HuysmanLieven Van Meulebroek

2016

Application of drought and salt stress can improve tomato fruit quality without jeopardising production

Bart Van de WalLieven Van MeulebroekKathy Steppe

Discovery of a urinary biomarker to discriminate between semi-endogenous and exogenous thiouracil in cattle

Lieven Van MeulebroekJella WautersJulie Vanden BusschePhilippe DelahautLynn Vanhaecke

In vitro DNA adduct profiling to mechanistically link red meat consumption to colon cancer promotion

Lieselot HemeryckCaroline RomboutsThomas Van HeckeLieven Van MeulebroekJulie VandenbusscheStefaan De SmetLynn Vanhaecke

A1 Journal Article in TOXICOLOGY RESEARCH

Metabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle

Nathalie De ClercqJulie Vanden BusscheLieven Van MeulebroekSiska CroubelsPhilippe DelahautDieter BuystJosé MartinsJianru Stahl-ZengLynn Vanhaecke

A1 Journal Article in METABOLOMICS

Metabolic fingerprinting to assess the impact of salinity on carotenoid content in developing tomato fruits

Lieven Van MeulebroekJochen HanssensKathy SteppeLynn Vanhaecke

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolisation and transfer of marine toxins from algae to molluscs

Gabriel Orellana MancillaLynn VanhaeckeColin JanssenLieven Van Meulebroek

Rapeseed-enriched diet and low-level thiouracil administration in cattle : impact on thyroid hormone metabolism

Jella WautersJulie KieboomsJulie Vanden BusscheEric FichantPhilippe DelahautLieven Van MeulebroekLynn Vanhaecke

UHPLC coupled to hybrid high resolution MS for digestion metabolomics and DNA adductomics

Lynn VanhaeckeLieselot HemeryckCaroline RomboutsLieven Van MeulebroekJulie Vanden Bussche

2015

A metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit

Lieven Van MeulebroekJulie Vanden BusscheNathalie De ClercqKathy SteppeLynn Vanhaecke

A1 Journal Article in METABOLOMICS

DNA adductomics to unravel the genotoxic effects of red meat consumption

Lieselot HemeryckCaroline RomboutsLieven Van MeulebroekJulie Vanden BusscheLynn Vanhaecke

Digestion metabolomics and DNA adductomics as a tool for phenotype discrimination

Julie Vanden BusscheLieselot HemeryckCaroline RomboutsLieven Van MeulebroekLynn Vanhaecke

Mapping of the DNA adductome to study the genotoxic effects of red meat consumption

Lieselot HemeryckCaroline RomboutsLieven Van MeulebroekJulie Vanden BusscheLynn Vanhaecke

Priming of wheat with the green leaf volatile Z-3-hexenyl acetate enhances defense against Fusarium graminearum but boosts deoxynivalenol production

Maarten AmeyeKris AudenaertNathalie De ZutterKathy SteppeLieven Van MeulebroekLynn VanhaeckeDavid De VleesschauwerGeert HaesaertGuy Smagghe

A1 Journal Article in PLANT PHYSIOLOGY

Quantification and profiling of lipophilic marine toxins in microalgae by UHPLC coupled to high-resolution orbitrap mass spectrometry

Gabriel Orellana MancillaLieven Van MeulebroekSarah Van VoorenMaarten De RijckeMichiel VandegehuchteColin JanssenLynn Vanhaecke

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The impact of stress on the prevalence of prednisolone in bovine urine: a metabolic fingerprinting approach

Nathalie De ClercqLieven Van MeulebroekJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2014

A metabolomic framework to study the regulating role of phytohormones towards carotenoids in tomato fruit

Lieven Van MeulebroekLynn VanhaeckeKathy Steppe

A novel approach to the quantitative detection of anabolic steroids in bovine muscle tissue by means of a hybrid quadrupole time-of-flight-massspectrometry instrument

Julie Vanden BusscheAnneleen DecloedtLieven Van MeulebroekNathalie De ClercqStephen LockJianru Stahl-ZengLynn Vanhaecke

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

High-resolution Orbitrap mass spectrometry for the analysis of carotenoids in tomato fruit: validation and comparative evaluation towards UV-VIS and tandem mass spectrometry

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Stem girdling affects the quantity of CO2 transported in xylem as well as CO2 efflux from soil

Jasper BloemenLaura AgneessensLieven Van MeulebroekDoug P AubreyMary Anne McGuireRobert TeskeyKathy Steppe

A1 Journal Article in NEW PHYTOLOGIST

Unravelling the phytohormonal status and carotenoid profile of tomato plants by using metabolomics, including generic extraction and UHPLC-Orbitrap-MS

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

Validation of a confirmatory method for lipophilic marine toxins in shellfish using UHPLC-HR-Orbitrap MS

Gabriel Orellana MancillaJulie Vanden BusscheLieven Van MeulebroekMichiel VandegehuchteColin JanssenLynn Vanhaecke

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

2013

A better understanding of carotenoid metabolism in tomato fruit by using the metabolomics capabilities of full-scan Orbitrap MS

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

High resolution Orbitrap mass spectrometry in comparison with tandem mass spectrometry for confirmation of anabolic steroids in meat

Lynn VanhaeckeLieven Van MeulebroekNathalie De ClercqJulie Vanden Bussche

A1 Journal Article in ANALYTICA CHIMICA ACTA

The analytical performance of high resolution Orbitrap mass spectrometry for the detection and quantitation of carotenoids in tomato fruit

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

Understanding the effect of carbon status on stem diameter variations

Tom De SwaefSteven DrieverLieven Van MeulebroekLynn VanhaeckeLeo FM MarcelisKathy Steppe

A1 Journal Article in ANNALS OF BOTANY

Unravelling the regulating role of phytohormones towards carotenoid metabolism in tomato fruit by using the metabolomic screening possibilities of Orbitrap-MS

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

2012

Metabolomic profiling of phytohormones in tomato: exploiting the high resolution and full scan characteristics of the Orbitrap mass spectrometer

Lieven Van MeulebroekKathy SteppeLynn Vanhaecke

Metabolomic profiling of phytohormones in tomato: the crucial role of generic extraction and full-scan high resolution Orbitrap mass spectrometry

Lieven Van MeulebroekKathy SteppeLynn Vanhaecke

U-HPLC-MS/MS to quantify liposoluble antioxidants in red-ripe tomatoes, grown under different salt stress levels

Lieven Van MeulebroekLynn VanhaeckeTom De SwaefKathy SteppeHubert De Brabander

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ultra-high performance liquid chromatography coupled to high resolution Orbitrap mass spectrometry for metabolomic profiling of the endogenous phytohormonal status of the tomato plant

Lieven Van MeulebroekJulie Vanden BusscheKathy SteppeLynn Vanhaecke

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

2011

U-HPLC-MS/MS analysis to quantify the antioxidant content of tomatoes subjected to different cultivation conditions

Lieven Van MeulebroekLynn VanhaeckeTom De SwaefKathy SteppeHubert De Brabander

U-HPLC-MS/MS analysis to quantify the antioxidant content of tomatoes subjected to different cultivation conditions

Lieven Van MeulebroekLynn VanhaeckeTom De SwaefKathy SteppeHubert De Brabander