Research Explorer

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Researcher

Kevin Braeckmans

Publications & Research Data

Awards & Distinctions

333 Results

2026

Improving transport efficiency for large human cells for enabling accurate determination of cellular nanoparticle uptake via SC-ICP-TOF-MS

Mina NikolićAna Lores PadínThibaut Van AckerTina SmetsIlia GoemaereAmin AhmadKevin BraeckmansEduardo Bolea FernandezFrank Vanhaecke

A1 Journal Article in TALANTA

Lipid-stabilized ICG nanoaggregates for the photodisruption of vitreous opacities

Pouria RamezaniJan FélixYera UssembayevMariana Hugo Borges Barreto SilvaIne LentackerRein VerbekeKevin BraeckmansStefaan De SmedtFélix Sauvage

A1 Journal Article in MATERIALS TODAY BIO

Overcoming size barriers in retinal gene therapy via lipid nanoparticle-mediated delivery of full-length eys DNA

Sarah GoddaerEmma De CosterElise CallensEmma Van CaenegemOlivier Van den HeuleRob W. J. CollinKaren PeynshaertFilip Van NieuwerburghKevin BraeckmansKatrien Remaut

A1 Journal Article in DRUG DELIVERY AND TRANSLATIONAL RESEARCH

Photothermal transport for guiding nanoparticles through the vitreous humor

Léa GuerassimoffYera UssembayevLouise De ClerckDeep PunjMartijn van den BroekFilip BeunisKatrien RemautKevin BraeckmansStefaan De SmedtFélix Sauvage

A1 Journal Article in ADVANCED SCIENCE

2025

Carriers, cargo, and consequences : analytical strategies to resolve heterogeneity in lipid nanoparticle delivery

Sarah GoddaerKatrien RemautJo VandesompeleKevin Braeckmans

Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis

An-Katrien MinnaertVan-Phuc NguyenAranit HarizajIlia GoemaereBart Van PuyveldeMaarten DhaenensFélix SauvageDieter DeforceStefano SalmasoPaolo Caliceti et al.

U Journal Article in Journal of Controlled Release

Developing a single-cell ICP-TOF-MS method for photoporation studies : improving low transport efficiencies for large human cells

Mina NikolićAna Lores PadínThibaut Van AckerIlia GoemaereKevin BraeckmansFrank Vanhaecke

Gentle and efficient engineering of primary human NK cells by photoporation with polydopamine nanosensitizers

Charlotte HinnekensJana RamonM. BirbenW.T.V. GermeraadA. HarizajMargo De VelderStefaan De SmedtBart VandekerckhoveKevin BraeckmansJuan Fraire

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Immunogenic cell death as interplay between physical anticancer modalities and immunotherapy

Yanou EngelenRobin DemuynckJana RamonK. BreckpotStefaan De SmedtGuillaume LajoinieKevin BraeckmansDmitri KryskoIne Lentacker

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Impact of pneumatic tube transportation on the aggregation of monoclonal antibodies in clinical practice

Michaela CohrsNele ClottensPieter RamautKevin BraeckmansStefaan De SmedtTieneke BautersHristo Svilenov

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Intrinsic differential scanning fluorimetry for protein stability assessment in microwell plates

Michaela CohrsAlastair DavyManon Van AckereStefaan De SmedtKevin BraeckmansMarkus EpeHristo Svilenov

A1 Journal Article in MOLECULAR PHARMACEUTICS

Lipid-stabilized ICG nanoaggregates for the photodisruption of vitreous opacities

Pouria RamezaniJan FélixMariana Hugo Borges Barreto SilvaIne LentackerRein VerbekeKevin BraeckmansStefaan De SmedtFélix Sauvage

Nanosecond laser pulses facilitating efficient and specific cell killing with doxorubicin‐loaded gold nanoparticles targeted to the folate receptor

Ilia GoemaereAnna CieloRaffaella DanieleFrancesca MastrottoStefaan De SmedtWinnok H. De VosStefano SalmasoKevin Braeckmans

A2 Journal Article in SMALL SCIENCE

Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules

Dongyang MiaoYuanyuan SongStijn De MunterHuining XiaoBart VandekerckhoveStefaan De SmedtChaobo HuangKevin BraeckmansRanhua Xiong

A1 Journal Article in NATURE PROTOCOLS

Pre-formation loading of extracellular vesicles with exogenous molecules using photoporation

Jana RamonCláudio PinheiroCharysse VandendriesscheEstefanía Lozano-AndrésHerlinde De KeersmaeckerDeep PunjJuan FraireEdward GeeurickxMarca H. M. WaubenPieter Vader et al.

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

Risk assessment of pneumatic tube systems for in-hospital transportation of biotherapeutics

Michaela CohrsPaula E. BorgonjeNele ClottensPieter RamautKevin BraeckmansStefaan De SmedtHristo SvilenovTieneke Bauters

A1 Journal Article in JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Tunable electrokinetic motion of charged nanoparticles in an aqueous solution using interdigitated microelectrodes

Farshad RezakhanlooYera UssembayevMohammadreza BahramiFilip BeunisKevin BraeckmansIlia GoemaereDeep PunjAmin AhmadLouis Van der MeerenKristiaan Neyts

A1 Journal Article in NANOMATERIALS

2024

Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics

Jana RamonYanou EngelenHerlinde De KeersmaeckerIlia GoemaereDeep PunjJulián Mejía MoralesCédric BonteGeert BerxEsther HosteStephan Stremersch et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Non-viral delivery of RNA for therapeutic T cell engineering

Dominika BerdeckaStefaan De SmedtWinnok H. De VosKevin Braeckmans

A1 Journal Article in ADVANCED DRUG DELIVERY REVEIWS

Non-viral engineering of natural killer cells : exploring nanoparticle-sensitized photoporation as a promising transfection technology

Charlotte HinnekensKevin BraeckmansJuan Fraire

Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity

Heyang ZhangJo VandesompeleKevin BraeckmansStefaan De SmedtKatrien Remaut

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

Photoporation of NK-92MI cells with biodegradable polydopamine nanosensitizers as a promising strategy for the generation of engineered NK cell therapies

Charlotte HinnekensAranit HarizajDominika BerdeckaIlke AernoutMolood ShariatiStefanie PeetersEva LionStefaan De SmedtBart VandekerckhoveKevin Braeckmans et al.

A1 Journal Article in APPLIED MATERIALS TODAY

Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes

Laurens LégerChloë De ClercqJeffrey AaldersKiara Van Acker-VerbercktKevin BraeckmansJolanda van Hengel

A2 Journal Article in METHODSX

Porcine ex-vivo intestinal mucus has age-dependent blocking activity against transmissible gastroenteritis virus

Waqar SaleemNathan CarpentierCharlotte HinnekensDayoung OhSandra Van VlierbergheKevin BraeckmansHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Towards cell state-preserving delivery of therapeutic macromolecules into macrophages with polydopamine-sensitized photoporation

Ilia GoemaereKevin BraeckmansWinnok De Vos

2023

Capric acid and myristic acid permeability enhancers in curved liposome membranes

Samaneh DavoudiKoen RaemdonckKevin BraeckmansAn Ghysels

A1 Journal Article in JOURNAL OF CHEMICAL INFORMATION AND MODELING

Delivery of macromolecules in unstimulated T cells by photoporation with polydopamine nanoparticles

Dominika BerdeckaAranit HarizajIlia GoemaereDeep PunjGlenn GoetgelukStijn De MunterHerlinde De KeersmaeckerVeerle BoterbergPeter DubruelBart Vandekerckhove et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Designing of gradient scaffolds and their applications in tissue regeneration

Ananya PattnaikA. Swaroop SanketSanghamitra PradhanRajashree SahooSudiptee DasSwarnaprbha PanyTimothy E. L. DouglasRambabu DandelaQiang LiuJaykumar Rajadas et al.

A1 Journal Article in BIOMATERIALS

Immunotherapy : towards engineered NK cell therapy : mRNA transfection of NK92 cells by photoporation with biodegradable polydopamine nanosensitizers

Charlotte HinnekensAranit HarizajIlia GoemaereStefaan De SmedtBart VandekerckhoveJuan FraireKevin Braeckmans

Laser‐scanning microscopy for electrophoretic mobility characterization of single nanoparticles

Lucas OorlynckYera UssembayevIngrid Amer CidJuan FraireCharlotte HinnekensKevin BraeckmansFilip Strubbe

A1 Journal Article in PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Light-triggered mechanical disruption of extracellular barriers by swarms of enzyme-powered nanomotors for enhanced delivery

Juan FraireMaria GuixAna C. HortelaoNoelia Ruiz-GonzálezAnna C. BakeneckerPouria RamezaniCharlotte HinnekensFélix SauvageStefaan De SmedtKevin Braeckmans et al.

A1 Journal Article in ACS NANO

Non-viral engineering of NK cells

Charlotte HinnekensStefaan De SmedtJuan FraireKevin Braeckmans

A1 Journal Article in BIOTECHNOLOGY ADVANCES

Novel opto-fluidic drug delivery system for efficient cellular transfection

Majid LayachiAnthony TreizebréLaurent HayDavid GilbertJean PesezQuentin D’AcremontKevin BraeckmansQuentin ThommenEmmanuel Courtade

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

Photothermal nanofibers enable macromolecule delivery in unstimulated human T cells

Dominika BerdeckaManon MinsartTao LuDeep PunjRiet De RyckeMina NikolićEduardo Bolea FernandezFrank VanhaeckeRanhua XiongStefaan De Smedt et al.

A1 Journal Article in APPLIED MATERIALS TODAY

Photothermal nanomaterial-mediated photoporation

Ranhua XiongFélix SauvageJuan FraireChaobo HuangStefaan De SmedtKevin Braeckmans

A1 Journal Article in ACCOUNTS OF CHEMICAL RESEARCH

Porcine intestinal mucus has an age-dependent blocking activity against a porcine coronavirus (Transmissible Gastroenteritis Virus)

Waqar SaleemNathan CarpentierCharlotte HinnekensSandra Van VlierbergheKevin BraeckmansHans Nauwynck

Response surface methodology to efficiently optimize intracellular delivery by photoporation

Ilia GoemaereDeep PunjAranit HarizajJessica WoolstonSofie ThysKaren SterckStefaan De SmedtWinnok H. De VosKevin Braeckmans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Towards minimally invasive delivery of large molecules into human T cells by photoporation with polydopamine nanosensitizers and photothermal nanofibers

Dominika BerdeckaKevin BraeckmansWinnok De Vos

Unfolding the versatility of laser-induced vapor nanobubbles : from balancing intracellular delivery with regulated cell death to loading of extracellular vesicles

Jana RamonKevin BraeckmansKoen RaemdonckStephan Stremersch

2022

Bio-nanohybrid gelatin/quantum dots for cellular imaging and biosensing applications

Sangram Keshari SamalStefaan SoenenDario PuppiKarolien De WaelSanghamitra PatiStefaan De SmedtKevin BraeckmansPeter Dubruel

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Counting permeant crossings to assess the effect of membrane curvature and composition on the permeability rate

Samaneh DavoudiKoen RaemdonckKevin BraeckmansAn Ghysels

Explaining the working mechanism of laser‐activated irrigation and its action on microbial biofilms : a high‐speed imaging study

Rosalie SwimbergheRizos TzourmanasRoeland De MoorKevin BraeckmansTom CoenyeMaarten Meire

A1 Journal Article in INTERNATIONAL ENDODONTIC JOURNAL

Fast laser scanning imaging for single nanoparticle analysis

Lucas OorlynckYera UssembayevJuan FraireCharlotte HinnekensKevin BraeckmansFilip Strubbe

Gas-shearing synthesis of core–shell multicompartmental microparticles as cell-like system for enzymatic cascade reaction

Qingli QuXiaoli ZhangHossein RavanbakhshGuosheng TangJian ZhangYankang DengKevin BraeckmansStefaan De SmedtRanhua XiongChaobo Huang

A1 Journal Article in CHEMICAL ENGINEERING JOURNAL

Gene therapy to enhance angiogenesis in chronic wounds

Elnaz Shaabani SichaniMaryam SharifiaghdamReza Faridi-MajidiStefaan De SmedtKevin BraeckmansJuan Fraire

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery

Karen PeynshaertHelena VanlucheneKaat De ClerckAn-Katrien MinnaertMorgane VerhoevenNoémie GouspillouNezahat BostanToshio HisatomiGeraldine AccouFélix Sauvage et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Investigating membrane curvature and composition effect on membrane permeability by counting permeant crossings

Samaneh DavoudiKoen RaemdonckKevin BraeckmansAn Ghysels

Laser-induced nanobubbles safely ablate vitreous opacities in vivo

Félix SauvageVan Phuc NguyenYanxiu LiAranit HarizajJ. SebagDimitri RoelsViktor Van HavereKaren PeynshaertRanhua XiongJuan Fraire et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

Laser-scanning imaging and electrophoresis of single nanoparticles

Filip StrubbeLucas OorlynckYera UssembayevJuan FraireCharlotte HinnekensKevin Braeckmans

Layer-by-Layer self-assembly technique : a tunable tool for delivery of therapeutic nucleic acids

Elnaz Shaabani SichaniJuan FraireKevin Braeckmans

LBL delivery systems for intracellular delivery of therapeutic nucleic acids

Maryam SharifiaghdamJuan FraireKevin Braeckmans

Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells

Juan FraireElnaz Shaabani SichaniMaryam SharifiaghdamMatthias RombautCharlotte HinnekensDawei HuaJana RamonLaurens RaesEduardo Bolea FernandezToon Brans et al.

A1 Journal Article in NATURE COMMUNICATIONS

Multicompartmental microcapsules for enzymatic cascade reactions prepared through gas shearing and surface gelation

Qingli QuWeixia ChengXiaoli ZhangAying ZhouYankang DengMiaomiao ZhuTianjiao ChuBella B. ManshianRanhua XiongStefaan J. Soenen et al.

A1 Journal Article in BIOMACROMOLECULES

Non-viral siRNA delivery to T cells : challenges and opportunities in cancer immunotherapy

Jelter Van HoeckKevin BraeckmansStefaan De SmedtKoen Raemdonck

A1 Journal Article in BIOMATERIALS

Photodisruption of the inner limiting membrane : exploring ICG loaded nanoparticles as photosensitizers

Kaat De ClerckGeraldine AccouFélix SauvageKevin BraeckmansStefaan De SmedtKatrien RemautKaren Peynshaert

A1 Journal Article in PHARMACEUTICS

Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis

Elke De SchutterJana RamonBenjamin PfeutyCaroline De TenderStephan StremerschKoen RaemdonckKen Op de BeeckWim DeclercqFranck RiquetKevin Braeckmans et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

The cellular response to plasma membrane disruption for nanomaterial delivery

Gaëlle HouthaeveStefaan De SmedtKevin BraeckmansWinnok H. De Vos

A1 Journal Article in NANO CONVERGENCE

Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane

Gaëlle HouthaeveGerardo García-Díaz BarrigaStephan StremerschHerlinde De KeersmaeckerJuan FraireJo VandesompelePieter MestdaghStefaan De SmedtKevin BraeckmansWinnok De Vos

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Understanding membrane permeability of drug releasing liposomes from molecular dynamics simulations : effect of curvature and composition

Samaneh DavoudiKoen RaemdonckKevin BraeckmansAn Ghysels

Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy

An-Katrien MinnaertLoes van SchieHendrik GrootaertJonas HimpeSimon DevosWannes WeytsHerlinde De KeersmaeckerKevin BraeckmansElisabeth Van AkenJoris Delanghe et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2021

Black phosphorus mediated photoporation : a broad absorption nanoplatform for intracellular delivery of macromolecules

Jielin WangAranit HarizajYongbo WuXiaofang JiangToon BransJuan FraireJulián Mejía MoralesStefaan De SmedtZhilie TangRanhua Xiong et al.

A1 Journal Article in NANOSCALE

Bubble forming films for spatial selective cell killing

Dawei HuaAranit HarizajMike WelsToon BransStephan StremerschHerlinde De KeersmaeckerEduardo Bolea FernandezFrank VanhaeckeDimitri RoelsKevin Braeckmans et al.

A1 Journal Article in ADVANCED MATERIALS

Carbon quantum dots as a dual platform for the inhibition and light-based destruction of collagen fibers : implications for the treatment of eye floaters

Alexandre BarrasFélix SauvageInès De HoonKevin BraeckmansDawei HuaGaëtan BuvatJuan FraireChristophe LethienJ. SebagMichael Harrington et al.

A1 Journal Article in NANOSCALE HORIZONS

Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering

Laurens RaesMelissa PilleAranit HarizajGlenn GoetgelukJelter Van HoeckStephan StremerschJuan FraireToon BransOlivier Gerrit de JongRoel Maas-Bakker et al.

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Concentration gradients in material sciences : methods to design and biomedical applications

Dawei HuaRanhua XiongKevin BraeckmansBenoit ScheidChaobo HuangFélix SauvageStefaan De Smedt

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells

Aranit HarizajBenedicte DescampsChristophe MangodtStephan StremerschArianna StoppaLieve BalcaenToon BransHilde De RoosterNausikaa DevriendtJuan Fraire et al.

A1 Journal Article in BIOMATERIALS SCIENCE

Detection of ovalbumin amyloid-like fibrils at the oil-water interface in oil-in-water emulsions by spinning disk confocal microscopy

Arne HuystHerlinde De KeersmaeckerLomme DeleuKevin BraeckmansJan DelcourPaul Van der Meeren

Detection of ovalbumin amyloid-like fibrils at the oil-water interface in oil-in-water emulsions by spinning disk confocal microscopy

Arne HuystHerlinde De KeersmaeckerLomme J. DeleuKevin BraeckmansJan A. DelcourPaul Van der Meeren

A1 Journal Article in FOOD STRUCTURE-NETHERLANDS

Enhanced siRNA delivery and selective apoptosis induction in H1299 cancer cells by layer-by-layer-assembled Se nanocomplexes : toward more efficient cancer therapy

Maryam SharifiaghdamElnaz Shaabani SichaniZeynab SharifiaghdamHerlinde De KeersmaeckerRiet De RyckeStefaan De SmedtReza Faridi-MajidiKevin BraeckmansJuan Fraire

A1 Journal Article in FRONTIERS IN MOLECULAR BIOSCIENCES

Hydrogel-induced cell membrane disruptions enable direct cytosolic delivery of membrane-impermeable cargo

Jelter Van HoeckThijs Van de VyverAranit HarizajGlenn GoetgelukPieterjan MerckxJing LiuMike WelsFélix SauvageHerlinde De KeersmaeckerChristian Vanhove et al.

A1 Journal Article in ADVANCED MATERIALS

In-depth analysis of vapor nanobubble-mediated permeabilization at the level of the plasma membrane and nuclear envelope

Gaëlle HouthaeveWinnok De VosKevin Braeckmans

Increasing angiogenesis factors in hypoxic diabetic wound conditions by siRNA delivery : additive effect of LbL-gold nanocarriers and desloratadine-induced lysosomal escape

Elnaz Shaabani SichaniMaryam SharifiaghdamJoris LammensHerlinde De KeersmaeckerChris VervaetThomas De BeerElahe MotevaseliMohammad Hossein GhahremaniParvin MansouriStefaan De Smedt et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intracellular delivery of mRNA and proteins by VNB photoporation for cancer immunotherapy

Laurens RaesKevin BraeckmansKoen Raemdonck

Layer by layer assembled chitosan-coated gold nanoparticles for enhanced siRNA delivery and silencing

Elnaz Shaabani SichaniMaryam SharifiaghdamHerlinde De KeersmaeckerRiet De RyckeStefaan De SmedtReza Faridi-MajidiKevin BraeckmansJuan Fraire

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipoplexes to deliver oligonucleotides in gram-positive and gram-negative bacteria : towards treatment of blood infections

Sara PereiraRita Sobral SantosLuís MoreiraNuno GuimarãesMariana GomesHeyang ZhangKatrien RemautKevin BraeckmansStefaan De SmedtNuno Filipe Azevedo

A1 Journal Article in PHARMACEUTICS

Macrophage reprogramming into a pro-healing phenotype by siRNA delivered with LBL assembled nanocomplexes for wound healing applications

Maryam SharifiaghdamElnaz Shaabani SichaniZeynab SharifiaghdamHerlinde De KeersmaeckerBart LucasJoris LammensHossein GhanbariLadan Teimoori-ToolabiChris VervaetThomas De Beer et al.

A1 Journal Article in NANOSCALE

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger

Aranit HarizajFilip Van HauwermeirenStephan StremerschRiet De RyckeHerlinde De KeersmaeckerToon BransJuan FraireKarolien GrauwenStefaan De SmedtIne Lentacker et al.

A1 Journal Article in NANOSCALE

Non-viral transfection technologies for next-generation therapeutic T cell engineering

Laurens RaesStefaan De SmedtKoen RaemdonckKevin Braeckmans

A1 Journal Article in BIOTECHNOLOGY ADVANCES

PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages

Sohaib MahriEléonore HardyTobias WilmsHerlinde De KeersmaeckerKevin BraeckmansStefaan De SmedtCynthia BosquillonRita Vanbever

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells

Aranit HarizajMike WelsLaurens RaesStephan StremerschGlenn GoetgelukToon BransBart VandekerckhoveFélix SauvageStefaan De SmedtIne Lentacker et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Photothermal nanofibres enable safe engineering of therapeutic cells

Ranhua XiongDawei HuaJelter Van HoeckDominika BerdeckaLaurens LégerStijn De MunterJuan FraireLaurens RaesAranit HarizajFélix Sauvage et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

Physical transfection technologies for macrophages and dendritic cells in immunotherapy

Aranit HarizajStefaan De SmedtIne LentackerKevin Braeckmans

A1 Journal Article in EXPERT OPINION ON DRUG DELIVERY

Stimuli-responsive nanobubbles for biomedical applications

Ranhua XiongRonald X. XuChaobo HuangStefaan De SmedtKevin Braeckmans

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

Together is better : mRNA co‐encapsulation in lipoplexes is required to obtain ratiometric co‐delivery and protein expression on the single cell level

Heyang ZhangJeroen BussmannFlorian H. HuhnkeJoke DevoldereAn-Katrien MinnaertWim JiskootFriedhelm SerwaneJoachim SpatzMagnus RödingStefaan De Smedt et al.

A1 Journal Article in ADVANCED SCIENCE

Vapor nanobubble-mediated photoporation constitutes a versatile intracellular delivery technology

Jana RamonRanhua XiongStefaan De SmedtKoen RaemdonckKevin Braeckmans

A1 Journal Article in CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

2020

Does the mode of dispersion determine the properties of dispersed Pseudomonas aeruginosa biofilm cells?

Jasper WilleEline TeirlinckAndrea SassFilip Van NieuwerburghVolkhard KaeverKevin BraeckmansTom Coenye

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Faithful fabrication of biocompatible multicompartmental memomicrospheres for digitally color‐tunable barcoding

Guosheng TangLong ChenZixuan WangShuting GaoQingli QuRanhua XiongKevin BraeckmansStefaan De SmedtYu Shrike ZhangChaobo Huang

A1 Journal Article in SMALL

Fluorescence-based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts

Heyang ZhangKoen RomboutsLaurens RaesRanhua XiongStefaan De SmedtKevin BraeckmansKatrien Remaut

A1 Journal Article in ADVANCED BIOSYSTEMS

Improving antibiotics' penetration and efficiency for treating biofilm infections by laser-induced vapor nanobubbles

Eline TeirlinckRanhua XiongToon BransKatrien ForierJuan FraireHeleen Van AckerStefaan De SmedtTom CoenyeKevin Braeckmans

Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation

Laurens RaesStephan StremerschJuan FraireToon BransGlenn GoetgelukStijn De MunterLien Van HoeckeRein VerbekeJelter Van HoeckRanhua Xiong et al.

A1 Journal Article in NANO-MICRO LETTERS

Intracellular labeling of live cells with extrinsic probes by laser-induced photoporation

Jing LiuKevin BraeckmansRanhua Xiong

Intracellular labeling with extrinsic probes : delivery strategies and applications

Jing LiuJuan FraireStefaan De SmedtRanhua XiongKevin Braeckmans

A1 Journal Article in SMALL

Light-responsive nanoparticles : from bio-imaging to intracellular delivery

Aranit HarizajKevin BraeckmansIne LentackerDirk Poelman

Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation

Jing LiuTim HebbrechtToon BransEef ParthoensSaskia LippensChengnan LiHerlinde De KeersmaeckerWinnok H. De VosStefaan De SmedtRabah Boukherroub et al.

A1 Journal Article in NANO RESEARCH

Materials and technologies to combat counterfeiting of pharmaceuticals : current and future problem tackling

Heyang ZhangDawei HuaChaobo HuangSangram Keshari SamalRanhua XiongFélix SauvageKevin BraeckmansKatrien RemautStefaan De Smedt

A1 Journal Article in ADVANCED MATERIALS

Nanobody click chemistry for convenient site-specific fluorescent labelling, single step immunocytochemistry and delivery into living cells by photoporation and live cell imaging

Tim HebbrechtJing LiuOlivier ZwaenepoelGaelle BoddinChloé Van LeeneKlaas DecoeneAnnemieke MadderKevin BraeckmansJan Gettemans

A1 Journal Article in NEW BIOTECHNOLOGY

Nanomaterials to avoid and destroy protein aggregates

Félix SauvageJoost SchymkowitzFrederic RousseauBela Z. SchmidtKatrien RemautKevin BraeckmansStefaan De Smedt

A1 Journal Article in NANO TODAY

Surface functionalization with polyethylene glycol and polyethyleneimine improves the performance of graphene-based materials for safe and efficient intracellular delivery by laser-induced photoporation

Jing LiuChengnan LiToon BransAranit HarizajShana Van de SteeneThomas De BeerStefaan De SmedtSabine SzuneritsRabah BoukherroubRanhua Xiong et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment

Yining XuHerlinde De KeersmaeckerKevin BraeckmansStefaan De SmedtPatrice D. CaniVéronique PréatAna Beloqui

A1 Journal Article in BIOMATERIALS

Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis

Juan FraireGaëlle HouthaeveJing LiuLaurens RaesLotte VermeulenStephan StremerschToon BransGerardo Garcia-Diaz BarrigaSarah De KeulenaerFilip Van Nieuwerburgh et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2019

Biocompatible lipid‐coated persistent luminescent nanoparticles for in vivo imaging of dendritic cell migration

Aranit HarizajOlivier De ClercqBenedicte DescampsChristian VanhoveStefaan De SmedtDirk PoelmanIne LentackerKevin Braeckmans

A1 Journal Article in PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Chromium-doped near-infrared persistent phosphors for in vivo imaging

Olivier De ClercqDirk PoelmanKevin Braeckmans

Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells

Lien Van HoeckeLaurens RaesStephan StremerschToon BransJuan FraireRia RoelandtWim DeclercqPeter VandenabeeleKoen RaemdonckKevin Braeckmans et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Efficient endocytosis of inorganic nanoparticles with zwitterionic surface functionalization

Emile DrijversJing LiuAranit HarizajUlrich WiesnerKevin BraeckmansZeger HensTangi Aubert

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Exploring light-sensitive nanocarriers for simultaneous triggered antibiotic release and disruption of biofilms upon generation of laser-induced vapor nanobubbles

Eline TeirlinckAlexandre BarrasJing LiuJuan FraireTatu LajunenRanhua XiongKatrien ForierChengnan LiArto UrttiRabah Boukherroub et al.

A1 Journal Article in PHARMACEUTICS

Gas‐shearing fabrication of multicompartmental microspheres : a one‐step and oil‐free approach

Guosheng TangRanhua XiongDan LvRonald X. XuKevin BraeckmansChaobo HuangStefaan De Smedt

A1 Journal Article in ADVANCED SCIENCE

Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells

Laurens RaesClarissa Van HeckeJulie MichielsStephan StremerschJuan FraireToon BransRanhua XiongStefaan De SmedtLinos VandekerckhoveKoen Raemdonck et al.

A1 Journal Article in CRYSTALS

Improved label-free identification of individual exosome-like vesicles with Au@Ag nanoparticles as SERS substrate

Juan FraireStephan StremerschDavinia BouckaertTinne MonteyneThomas De BeerPieter WuytensRiet De RyckeAndre SkirtachKoen RaemdonckStefaan De Smedt et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Laser-induced vapor nanobubbles : the golden ticket to the biofilm center

Eline TeirlinckKevin BraeckmansTom Coenye

Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care

Eline TeirlinckJuan FraireHeleen Van AckerJasper WilleRosalie SwimbergheToon BransRanhua XiongMaarten MeireRoeland De MoorStefaan De Smedt et al.

A2 Journal Article in BIOFILM

Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration

Kaushik ThankiDelphine van EetveldeAntonia GeyerJuan FraireRemi HendrixHannelore Van EygenEmma PuttemanHaider SamiCristiane de Souza Carvalho-WodarzHenrik Franzyk et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Photoablation of human vitreous opacities by light-induced vapor nanobubbles

Félix SauvageJuan FraireKatrien RemautJ SebagKaren PeynshaertMichael HarringtonFrans J Van de VeldeRanhua XiongMarie-Jose TassignonToon Brans et al.

A1 Journal Article in ACS NANO

Sonoprinting of nanoparticle-loaded microbubbles : unraveling the multi-timescale mechanism

Silke RooversGuillaume LajoinieIne De CockToon BransHeleen DewitteKevin BraeckmansMichel VersuisStefaan De SmedtIne Lentacker

A1 Journal Article in BIOMATERIALS

The role of membrane vesicle secretion in Stenotrophomonas maltophilia in response to ciprofloxacin stress

Jolien VitseBart DevreeseKevin Braeckmans

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

Heleen Van AckerAurélie CrabbéDukas JurėnasLisa OstynAndrea SassSimon DaledMaarten DhaenensDieter DeforceEline TeirlinckHerlinde De Keersmaecker et al.

A2 Journal Article in BIOFILM

Trap levels in persistent phosphors for bio-imaging

Dirk PoelmanOlivier De ClercqJiaren DuAranit HarizajIne LentackerKevin Braeckmans

2018

Bypassing border control : nuclear envelope rupture in disease

Gaëlle HouthaeveJoke RobijnsKevin BraeckmansWinnok De Vos

A1 Journal Article in PHYSIOLOGY

Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles

Lotte VermeulenToon BransSangram Keshari SamalPeter DubruelJo DemeesterStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in ACS NANO

In vitro evaluation of anti-aggregation and degradation behavior of PEGylated polymeric nanogels under in vivo like conditions

Yinan ChenGeorge DakwarKevin BraeckmansTwan LammersWim E HenninkJosbert M Metselaar

A1 Journal Article in MACROMOLECULAR BIOSCIENCE

Intra-articular formulation of GE11-PLGA conjugate-based NPs for dexamethasone selective targeting : in vitro evaluation

Enrica ChiesaSilvia PisaniBarbara ColzaniRossella DoratiBice ContiTiziana ModenaKevin BraeckmansIda Genta

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Investigating the intracellular delivery of non-viral gene therapeutics : a focus on the endosomal barrier

Lotte VermeulenKevin BraeckmansKatrien Remaut

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

Eline TeirlinckRanhua XiongToon BransKatrien ForierJuan FraireHeleen Van AckerNele MatthijsRiet De RyckeStefaan De SmedtTom Coenye et al.

A1 Journal Article in NATURE COMMUNICATIONS

Loss of nuclear envelope integrity in aging and disease

Joke RobijnsGaëlle HouthaeveKevin BraeckmansWinnok De Vos

A1 Journal Article in International Review of Cell and Molecular Biology, vol. 336

Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy

Lotte VermeulenToon BransStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in NANO TODAY

Mucus-penetrating solid lipid nanoparticles for the treatment of cystic fibrosis : proof of concept, challenges and pitfalls

N NafeeKatrien ForierKevin BraeckmansM Schneider

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Nanomaterials and molecular transporters to overcome the bacterial envelope barrier : towards advanced delivery of antibiotics

Rita SantosCéu FigueiredoNuno F. AzevedoKevin BraeckmansStefaan De Smedt

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Nucleic acid loading and fluorescent labeling of isolated extracellular vesicles requires adequate purification

Stephan StremerschToon BransKevin BraeckmansStefaan De SmedtKoen Raemdonck

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ovarian tissue cryopreservation in female-to-male transgender persons : insights in ovarian histology and physiology after prolonged androgen treatment

Chloë De RooSylvie LiermanKelly TillemanKaren PeynshaertKevin BraeckmansMirte CaanenCornelis LambalkSteven WeyersPetra De Sutter

Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles

Lotte VermeulenJuan FraireLaurens RaesEllen De MeesterSarah De KeulenaerFilip Van NieuwerburghStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo LouAns De BeuckelaerGeorge DakwarKatrien RemautJohan GrootenKevin BraeckmansBruno De GeestEnrico MastrobattistaStefaan De KokerWim E. Hennink

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Quantifying the average number of nucleic acid therapeutics per nanocarrier by single particle tracking microscopy

Elisa ZagatoLotte VermeulenHeleen DewitteGriet Van ImschootRoosmarijn VandenbrouckeJo DemeesterStefaan De SmedtKristiaan NeytsKatrien RemautKevin Braeckmans

A1 Journal Article in MOLECULAR PHARMACEUTICS

Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy

Jing LiuRanhua XiongToon BransSaskia LippensEef ParthoensFrancesca Cella ZanacchiRaffaella MagrassiSantosh K SinghSreekumar KurungotSabine Szunerits et al.

A1 Journal Article in LIGHT-SCIENCE & APPLICATIONS

Selective labeling of individual neurons in dense cultured networks with nanoparticle-enhanced photoporation

Ranhua XiongPeter VerstraelenJo DemeesterAndre SkirtachJean-Pierre TimmermansStefaan De SmedtWinnok De VosKevin Braeckmans

A1 Journal Article in FRONTIERS IN CELLULAR NEUROSCIENCE

Silica@zirconia core@shell ceramics as vaccine nanocarriers

Livia Naszalyi NagyAranit HarizajEvert DhaeneKrisztina FehérKevin BraeckmansJosé Martins

Targeted perturbation of nuclear envelope integrity with vapor nanobubble-mediated photoporation

Gaëlle HouthaeveRanhua XiongJoke RobijnsBert LuyckxYasmine BeulqueToon BransCoen CampsteijnSangram Keshari SamalStephan StremerschStefaan De Smedt et al.

A1 Journal Article in ACS NANO

Technical implementations of light sheet microscopy

Elisa ZagatoToon BransStefaan De SmedtKatrien RemautKristiaan NeytsKevin Braeckmans

A1 Journal Article in MICROSCOPY RESEARCH AND TECHNIQUE

The proton sponge hypothesis : fable or fact?

Lotte VermeulenStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

2017

Coating of quantum dots strongly defines their effect on lysosomal health and autophagy

Karen PeynshaertStefaan J SoenenBella B ManshianShareen H DoakKevin BraeckmansStefaan De SmedtKatrien Remaut

A1 Journal Article in ACTA BIOMATERIALIA

Comparing photoporation and nucleofection for delivery of small interfering RNA to cytotoxic T cells

Laura WayteckRanhua XiongKevin BraeckmansStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy

Thomas MartensKaren PeynshaertThaís Leite NascimentoElias FattalMarcus KarlstetterThomas LangmannSerge PicaudJo DemeesterStefaan De SmedtKatrien Remaut et al.

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Expanding the biologist's toolbox with microfabricated sample holders for single objective SPIM and Single Particle Tracking for the characterization of nanomedicines

Elisa ZagatoKevin BraeckmansKatrien RemautKristiaan Neyts

Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid

George DakwarKevin BraeckmansWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in DRUG DELIVERY AND TRANSLATIONAL RESEARCH

Fast spatial-selective delivery into live cells

Ranhua XiongClaire DrullionPeter VerstraelenJo DemeesterAndre SkirtachCorinne AbbadieWinnok De VosStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Fertility preservation for trans men : frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing exhibit normal meiotic spindles

Sylvie LiermanKelly TillemanKevin BraeckmansKaren PeynshaertSteven WeyersGuy T'SjoenPetra De Sutter

A1 Journal Article in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Intracellular delivery of biopharmaceuticals and contrast agents by VNB photoporation and sizing nanomaterials in bio-fluids by FRAP

Ranhua XiongKevin BraeckmansStefaan De SmedtAndre Skirtach

Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus

Rita SantosGeorge DakwarElisa ZagatoToon BransCéu FigueiredoKoen RaemdonckNuno F AzevedoStefaan De SmedtKevin Braeckmans

A1 Journal Article in BIOMATERIALS

Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress

Simon DevosWouter Van PutteJolien VitseGonzalez Van DriesscheStephan StremerschWim Van Den BroeckKoen RaemdonckKevin BraeckmansHenning StahlbergMisha Kudryashev et al.

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Microfabricated devices for single objective single plane illumination microscopy (SoSPIM)

Elisa ZagatoToon BransSteven VerstuyftDries Van ThourhoutJeroen MissinneGeert Van SteenbergeJo DemeesterStefaan De SmedtKatrien RemautKristiaan Neyts et al.

A1 Journal Article in OPTICS EXPRESS

Ovarian tissue cryopreservation in female-to-male transgender people : insights into ovarian histology and physiology after prolonged androgen treatment

Chloë De RooSylvie LiermanKelly TillemanKaren PeynshaertKevin BraeckmansMirte CaanenCornelis LambalkSteven WeyersGuy T'SjoenMaria Cornelissen et al.

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy

Antoine FrèreAlexandra BaroniElodie HendrickAnne-Sophie DelvigneFrançois OrangeOlivier PeulenGeorge DakwarJérôme DiricqPhilippe DuboisBrigitte Evrard et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Penetrating the bacterial biofilm : challenges for antimicrobial treatment

Eline TeirlinckSangram Keshari SamalTom CoenyeKevin Braeckmans

Bookchapter in Functionalized nanomaterials for the management of microbial infection : a strategy to address microbial drug resistance

The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile

Bella B ManshianThomas MartensKarsten KantnerKevin BraeckmansStefaan De SmedtJo DemeesterGareth JS JenkinsWolfgang J ParakBeatriz PelazShareen H Doak et al.

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

Unraveling the potential of nucleic acid mimics to target Helicobacter pylori infections : the effect of biological barriers

Rita SantosNuno F AzevedoKevin BraeckmansStefaan De SmedtCéu Figueiredo

2016

Approximate Bayesian computation for estimating number concentrations of monodisperse nanoparticles in suspension by optical microscopy

Magnus RödingElisa ZagatoKatrien RemautKevin Braeckmans

A1 Journal Article in PHYSICAL REVIEW E

Cytosolic delivery of nanolabels prevents their asymmetric inheritance and enables extended quantitative in vivo cell imaging

Ranhua XiongFreya JorisSayuan LiangRiet De RyckeSaskia LippensJo DemeesterAndre SkirtachKoen RaemdonckUwe HimmelreichStefaan De Smedt et al.

A1 Journal Article in NANO LETTERS

Design of smart GE11-PLGA/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs : synthesis, preparation and in vitro/ex vivo characterization

Barbara ColzaniGiovanna SperanzaRossella DoratiBice ContiTiziana ModenaGiovanna BruniElisa ZagatoLotte VermeulenGeorge DakwarKevin Braeckmans et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Designing NIR persistent phosphors : LiGa5O8:Cr3+

Olivier De ClercqKatleen KorthoutPhilippe SmetJevgenij KusakovskijHenk VrielinckKevin BraeckmansDirk Poelman

Endocytosis and endosomal trafficking of DNA after gene electrotransfer in vitro

Christelle RosazzaHendrik DeschoutAnnette BuntzKevin BraeckmansMarie-Pierre RolsAndreas Zumbusch

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Exploring extracellular vesicles for siRNA delivery and Raman-based diagnostics

Stephan StremerschStefaan De SmedtKoen RaemdonckKevin Braeckmans

Fluorescent labeling of DNA : strategies, pitfalls and necessity for fluorescence microscopy investigations of gene therapy

Koen RomboutsKatrien RemautKevin Braeckmans

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies

Koen RomboutsKevin BraeckmansKatrien Remaut

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA

Tania FurstGeorge DakwarElisa ZagatoAnna LechanteurKatrien RemautBrigitte EvrardKevin BraeckmansGeraldine Piel

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

High oxygen tension increases global methylation in bovine 4-cell embryos and blastocysts but does not affect general retrotransposon expression

Wenwen LiKaren GoossensMario Van PouckeKatrien ForierKevin BraeckmansAnn Van SoomLuc Peelman

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

High-resolution synchrotron X-ray analysis of bioglass-enriched hydrogels

Svetlana GorodzhaTimothy DouglasSangram Keshari SamalRainer DetschKatarzyna Cholewa-KowalskaKevin BraeckmansAldo R BoccacciniAndre SkirtachVerena WeinhardtTilo Baumbach et al.

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Identification of individual exosome-like vesicles by surface enhanced Raman spectroscopy

Stephan StremerschMonica MarroBat-El PinchasikPieter BaatsenAn HendrixStefaan De SmedtPablo Loza-AlvarezAndre SkirtachKoen RaemdonckKevin Braeckmans

A1 Journal Article in SMALL

Intra- and interspecies effects of outer membrane vesicles from Stenotrophomonas maltophilia on β-lactam resistance

Simon DevosStephan StremerschKoen RaemdonckKevin BraeckmansBart Devreese

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Laser-assisted photoporation : fundamentals, technological advances and applications

Ranhua XiongSangram Keshari SamalJo DemeesterAndre SkirtachStefaan De SmedtKevin Braeckmans

A1 Journal Article in ADVANCES IN PHYSICS-X

LiGa5O8:Cr3+ as NIR persistent phosphor for in vivo imaging

Olivier De ClercqPhilippe SmetKevin BraeckmansDirk Poelman

Methods to follow intracellular trafficking of cell-penetrating peptides

Ly PaernastePiret ArukuuskElisa ZagatoKevin BraeckmansUlo Langel

A1 Journal Article in JOURNAL OF DRUG TARGETING

Near-infrared persistent luminescence for medical imaging

Dirk PoelmanOlivier De ClercqPhilippe SmetKevin Braeckmans

Rare earths for phosphor development: the final frontier?

Dirk PoelmanOlivier De ClercqJesse BoumanHeleen SijbomJonas JoosKatleen KorthoutKevin BraeckmansPhilippe Smet

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability

Ranhua XiongRoosmarijn VandenbrouckeKatleen BroosToon BransElien Van WonterghemClaude LibertJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in NATURE COMMUNICATIONS

YAGG:Cr3+ as NIR persistent phosphor for in vivo imaging

Olivier De ClercqJesse BoumanPhilippe SmetKevin BraeckmansDirk Poelman

2015

Bio-inspired pulmonary surfactant-modified nanogels : a promising siRNA delivery system

Lynn De BackerKevin BraeckmansMarc CA StuartJo DemeesterStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Biomimetic chitosan-calcium carbonate composite scaffolds for applications in bone regeneration

Timothy DouglasSangram Keshari SamalDavid SchaubroeckKevin BraeckmansAndre Skirtach

Biomimetic magnetic silk scaffolds

Sangram Keshari SamalMamoni DashTatiana ShelyakovaHeidi DeclercqMarc UhlarzManuel Banobre-LopezPeter DubruelMaria CornelissenThomas HerrmannsdorferJose Rivas et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Chromium doped persistent phosphors for medical imaging

Dirk PoelmanOlivier De ClercqPhilippe SmetKevin Braeckmans

Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Thomas MartensKatrien RemautHendrik DeschoutJohan FJ EngbersenWim E HenninkMies J van SteenbergenJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles

George DakwarKevin BraeckmansJo DemeesterWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori

Rita SantosGeorge DakwarRanhua XiongKatrien ForierKatrien RemautStephan StremerschNuno GuimarãesSilvia FonteneteJesper WengelMarina Leite et al.

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Efficient delivery of quantum dots in live cells by gold nanoparticle mediated photoporation

Ranhua XiongFreya JorisIne De CockJo DemeesterStefaan De SmedtAndre SkirtachKevin Braeckmans

Fluorescence recovery after photobleaching in material and life sciences: putting theory into practice

Niklas LorénJoel HagmanJenny K JonassonHendrik DeschoutDiana BerninFrancesca Cella-ZanacchiAlberto DiasproJames G McNallyMarcel AmelootNick Smisdom et al.

A1 Journal Article in QUARTERLY REVIEWS OF BIOPHYSICS

Frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing, for the purpose of fertility preservation for transsexual persons, show normal spindle formations

Sylvie LiermanKelly TillemanChloë De RooKevin BraeckmansKaren PeynshaertSteven WeyersGuy T'SjoenPetra De Sutter

Injectable self-gelling composite scaffolds based on gellan gum hydrogel and ion-loaded zeolites

Timothy DouglasAgata L SkwarczynskaJolanta WarcholBart LucasKevin BraeckmansAndre Skirtach

Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells

Ranhua XiongKoen RaemdonckKaren PeynshaertIne LentackerIne De CockJo DemeesterStefaan De SmedtAndre SkirtachKevin Braeckmans

Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

Stefano ColomboDongmei CunKatrien RemautMatt BunkerJianxin ZhangBirte Martin-BertelsenAnan YaghmurKevin BraeckmansHanne M. NielsenCamilla Foged

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Multilayered magnetic gelatin membrane scaffolds

Sangram Keshari SamalVitaly GoranovMamoni DashAlessandro RussoTatiana ShelyakovaPatrizio GraziosiLisa LungaroAlberto RiminucciMarc UhlarzManuel Banobre-Lopez et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Stealth monoolein-based nanocarriers for delivery of siRNA to cancer cells

Ana CN OliveiraKoen RaemdonckThomas MartensKoen RomboutsRosana Simón-VázquezCláudia BothelhoIvo LopesMarlene LúcioÁfrica González-FernándezM Elisabete CD Real Oliveira et al.

A1 Journal Article in ACTA BIOMATERIALIA

Targeted decationized polyplexes for siRNA delivery

Luis NovoKaori M TakedaTamara PettetaGeorge DakwarJoep B van den DikkenbergKatrien RemautKevin BraeckmansCornelus F van NostrumEnrico MastrobattistaWim E Hennink

A1 Journal Article in MOLECULAR PHARMACEUTICS

The effect of intracellular degradation on cytotoxicity and cell labeling efficacy of inorganic ligand-stabilized colloidal CdSe/CdS quantum dots

Stefaan SoenenSofie AbéBella B ManshianTangi AubertZeger HensStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF BIOMEDICAL NANOTECHNOLOGY

Transport mechanisms of squalenoyl-adenosine nanoparticles across the blood-brain barrier

Alice GaudinOya TagitDunja SobotSinda Lepetre-MouelhiJulie MouginThomas F MartensKevin BraeckmansValerie NicolasDidier DesmaeleStefaan De Smedt et al.

A1 Journal Article in CHEMISTRY OF MATERIALS

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis

Ine De CockElisa ZagatoKevin BraeckmansYing LuanNico de JongStefaan De SmedtIne Lentacker

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2014

A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus

Xiaoyun YangLennert SteukersKatrien ForierRanhua XiongKevin BraeckmansKristien Van ReethHans Nauwynck

A1 Journal Article in PLOS ONE

Bright and stable CdSe/CdS@SiO2 nanoparticles suitable for long term cell labeling

Tangi AubertDaniel WassmuthStefaan SoenenKevin BraeckmansZeger Hens

Bright and stable CdSe/CdS@SiO2 nanoparticles suitable for long-term cell labeling

Tangi AubertStefaan SoenenDaniel WassmuthMarco CirilloRik Van DeunKevin BraeckmansZeger Hens

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Chitosan nanoparticles for siRNA delivery : optimizing formulation to increase stability and efficiency

H RagelleR RivaG VandermeulenBroes NaeyeV PourcelleCS Le DuffC D'HaeseB NystenKevin BraeckmansStefaan De Smedt et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy

George DakwarElisa ZagatoJoris DelangheSabina HobelAchim AignerHannelore DenysKevin BraeckmansWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ACTA BIOMATERIALIA

Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells

Ranhua XiongKoen RaemdonckKaren PeynshaertIne LentackerIne De CockJo DemeesterStefaan De SmedtAndre SkirtachKevin Braeckmans

A1 Journal Article in ACS NANO

Cytotoxicity of cadmium-free quantum dots and their use in cell bioimaging

Stefaan SoenenBella B ManshianTangi AubertUwe HimmelreichJo DemeesterStefaan De SmedtZeger HensKevin Braeckmans

A1 Journal Article in CHEMICAL RESEARCH IN TOXICOLOGY

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Luís NovoLarissa Y RizzoSuzanne K GolombekGeorge DakwarBo LouKatrien RemautEnrico MastrobattistaCornelus F van NostrumWilhelm Jahnen-DechentFabian Kiessling et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Dioctadecyldimethylammonium:monoolein nanocarriers for efficient in vitro gene silencing

Ana Cristina Norbert OliveiraThomas MartensKoen RaemdonckRenata Danielle AdatiEloi FeitosaeCláudia BotelhoAndreia Castro GomesKevin BraeckmansMaría Elisabete Cunha Dias Real Oliveira

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

DNA counterstaining for methylation and hydroxymethylation immunostaining in bovine zygotes

Sonia Heras GarciaKatrien ForierKoen RomboutsKevin BraeckmansAnn Van Soom

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Effect of covalent fluorescence labeling of plasmid DNA on its intracellular processing and transfection with lipid-based carriers

Koen RomboutsThomas MartensElisa ZagatoJo DemeesterStefaan De SmedtKevin BraeckmansKatrien Remaut

A1 Journal Article in MOLECULAR PHARMACEUTICS

Electrospun polystyrene fibers for HIV entrapment

Chaobo HuangStefaan SoenenEllen van GulckJoanna RejmanGuido VanhamBart LucasBart GeersKevin BraeckmansVictor ShahinPieter Spanoghe et al.

A1 Journal Article in POLYMERS FOR ADVANCED TECHNOLOGIES

Equine oviduct explant culture: a basic model to decipher embryo-maternal communication

Hilde NelisKatharina D'HerdeKaren GoossensLynn VandenbergheBart LeemansKatrien ForierKatrien SmitsKevin BraeckmansLuc PeelmanAnn Van Soom

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Exploiting intrinsic nanoparticle toxicity: the pros and cons of nanoparticle-induced autophagy in biomedical research

Karen PeynshaertBella Barjouhi ManshianFreya JorisKevin BraeckmansStefaan De SmedtJo DemeesterStefaan Soenen

A1 Journal Article in CHEMICAL REVIEWS

FRAP in pharmaceutical research: practical guidelines and applications in drug delivery

Hendrik DeschoutKoen RaemdonckJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in PHARMACEUTICAL RESEARCH

Functional CdSe/CdS@SiO2 nanoparticles for bioimaging applications

Tangi AubertDaniel WassmuthStefaan SoenenRik Van DeunKevin BraeckmansZeger Hens

Intracellular delivery of nanomaterials: how to catch endosomal escape in the act

Thomas MartensKatrien RemautJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in NANO TODAY

Lipid and polymer nanoparticles for drug delivery to bacterial biofilms

Katrien ForierKoen RaemdonckStefaan De SmedtJo DemeesterTom CoenyeKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery

Katrien RemautViola OorschotKevin BraeckmansJudith KlumpermanStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Merging the best of both worlds : hybrid lipid-enveloped matrix nanocomposites in drug delivery

Koen RaemdonckKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids

Hendrik DeschoutKoen RaemdonckStephan StremerschPietro MaoddiGuillaume MernierPhilippe RenaudSebastien JiguetAn Hendrixmarc brackeRudy Van den Broecke et al.

A1 Journal Article in NANOSCALE

Optimizing delivery of gene nanomedicines towards the retina via intravitreal administration

Thomas MartensKevin BraeckmansStefaan De SmedtKatrien Remaut

Overcoming biological barriers to nanomedicines for the treatment of pulmonary biofilm infections in cystic fibrosis

Katrien ForierKevin BraeckmansKoen RaemdonckJo Demeester

Precisely and accurately localizing single emitters in fluorescence microscopy

Hendrik DeschoutFrancesca Cella ZanacchiMichael MlodzianoskiAlberto DiasproJoerg BewersdorfSamuel T HessKevin Braeckmans

A1 Journal Article in NATURE METHODS

Probing the size limit for nanomedicine penetration into Burkholderia multivorans and Pseudomonas aeruginosa biofilms

Katrien ForierAnne-Sophie MessiaenKoen RaemdonckHans NelisStefaan De SmedtJo DemeesterTom CoenyeKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery

Elisa ZagatoKatrien ForierThomas MartensKristiaan NeytsJo DemeesterStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in NANOMEDICINE

The cellular interactions of PEGylated gold nanoparticles : effect of PEGylation on cellular uptake and cytotoxicity

Stefaan SoenenBella B ManshianAbuelmagd M AbdelmonemJosé-María MontenegroSisareuth TanLieve BalcaenFrank VanhaeckeAlain R BrissonWolfgang J ParakStefaan De Smedt et al.

A1 Journal Article in PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

The effect of nanoparticle degradation on poly(methacrylic acid)-coated quantum dot toxicity : the importance of particle functionality assessment in toxicology

Stefaan SoenenJose-Maria MontenegroAbuelmagd AbdelmonemBella ManshianShareen DoakWolfgang ParakStefaan De SmedtKevin Braeckmans

A1 Journal Article in ACTA BIOMATERIALIA

The performance of gradient alloy quantum dots in cell labeling

Stefaan SoenenBella B ManshianUwe HimmelreichJo DemeesterKevin BraeckmansStefaan De Smedt

A1 Journal Article in BIOMATERIALS

Thiazolidinedione derivatives as novel agents against Propionibacterium acnes biofilms

Gilles BrackmanKatrien ForierAAA Al QuntarEvelien De CanckClaes E EnkMorris SrebnikKevin BraeckmansTom Coenye

A1 Journal Article in JOURNAL OF APPLIED MICROBIOLOGY

Unraveling the effects of siRNA carrier systems on cell physiology: a multiparametric approach demonstrated on dextran nanogels

Stefaan SoenenLynn De BackerBella ManshianShareen DoakKoen RaemdonckJo DemeesterKevin BraeckmansStefaan De Smedt

A1 Journal Article in NANOMEDICINE

2013

Assessing nanoparticle toxicity in cell-based assays : influence of cell culture parameters and optimized models for bridging the in vitro-in vivo gap

Freya JorisBella B ManshianKaren PeynshaertStefaan De SmedtKevin BraeckmansStefaan Soenen

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

Automatic particle detection in microscopy using temporal correlations

Magnus RödingHendrik DeschoutThomas MartensKristof NotelaersJohan HofkensMarcel AmelootKevin BraeckmansAila SärkkäMats Rudemo

A1 Journal Article in MICROSCOPY RESEARCH AND TECHNIQUE

Bright and stable CdSe/CdS@SiO2 nanoparticles : synthesis and bioimaging applications

Tangi AubertMarco CirilloAmelie BiermannHolger LangeStefaan SoenenKevin BraeckmansZeger Hens

Correlation of dual colour single particle trajectories for improved detection and analysis of interactions in living cells

Hendrik DeschoutThomas MartensDries VercauterenKatrien RemautJo DemeesterStefaan De SmedtKristiaan NeytsKevin Braeckmans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development of nanomedicines for the treatment of pulmonary biofilm infections: Insights from advanced fluorescence microscopy studies

Katrien ForierAnne-Sophie MessiaenMartijn RisseeuwSerge Van CalenberghHendrik DeschoutKoen RaemdonckHans NelisFabienne DanhierVéronique PréatFrans De Baets et al.

Distinguishing free and anomalous diffusion by rectangular fluorescence recovery after photobleaching : a Monte Carlo study

Ben De ClercqBart CleurenHendrik DeschoutKevin BraeckmansMarcel Ameloot

A1 Journal Article in JOURNAL OF BIOMEDICAL OPTICS

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles

Sander AA KooijmansStephan StremerschKevin BraeckmansStefaan De SmedtAn HendrixMatthew JA WoodRaymond M SchiffelersKoen RaemdonckPieter Vader

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Fluorescent non-porous silica nanoparticles for long-term cell monitoring: cytotoxicity and particle functionality

Stefaan SoenenBella ManshianShareen H DoakeStefaan De SmedtKevin Braeckmans

A1 Journal Article in ACTA BIOMATERIALIA

Improving FRAP and SPT for mobility and interaction measurements of molecules and nanoparticles in biomaterials

Hendrik DeschoutKevin BraeckmansKristiaan NeytsJo Demeester

In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier

Broes NaeyeHendrik DeschoutVicky CaveliersBenedicte DescampsKevin BraeckmansChristian VanhoveJo DemeesterTony LahoutteStefaan De SmedtKoen Raemdonck

A1 Journal Article in BIOMATERIALS

Light-addressable capsules as caged compound matrix for controlled triggering of cytosolic reactions

Markus OchsSusana Carregal-RomeroJoanna RejmanKevin BraeckmansStefaan De SmedtWolfgang Parak

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Measuring absolute nanoparticle number concentrations from particle count time series

Magnus RödingHendrik DeschoutKevin BraeckmansMats Rudemo

A1 Journal Article in JOURNAL OF MICROSCOPY

Measuring the intravitreal mobility of nanomedicines with single-particle tracking microscopy

Thomas MartensDries VercauterenKatrien ForierHendrik DeschoutKatrien RemautRik PaesenMarcel AmelootJohan FJ EngbersenJo DemeesterStefaan De Smedt et al.

A1 Journal Article in NANOMEDICINE

Polymer-coated nanoparticles interacting with proteins and cells: focusing on the sign of the net charge

Dominik HühnKarsten KantnerChristian GeidelStefan BrandholtIne De CockStefaan SoenenPilar Rivera GilJose Maria MontenegroKevin BraeckmansKlaus Müllen et al.

A1 Journal Article in ACS NANO

Polysaccharide-based nucleic acid nanoformulations

Koen RaemdonckThomas F MartensKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Rectangle FRAP for measuring diffusion with a laser scanning microscope

Ranhua XiongHendrik DeschoutJo DemeesterStefaan De SmedtKevin Braeckmans

Bookchapter in Fluorescence spectroscopy and microscopy : methods and protocols

Self-calibrated concentration measurements of polydisperse nanoparticles

M RödingHendrik DeschoutKevin BraeckmansA SärkkäM Rudemo

A1 Journal Article in JOURNAL OF MICROSCOPY

The biocompatibility of nanosized materials: intracellular nanoparticle stability and effects on toxicity and particle functionality

Stefaan SoenenStefaan De SmedtKevin Braeckmans

The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels

Lynn De BackerKevin BraeckmansJo DemeesterStefaan De SmedtKoen Raemdonck

A1 Journal Article in NANOMEDICINE

Towards theranostic multicompartment microcapsules: in-situ diagnostics and laser-induced treatment

Ranhua XiongStefaan SoenenKevin BraeckmansAndre Skirtach

A1 Journal Article in THERANOSTICS

Transport of nanoparticles and tobramycin-loaded liposomes in Burkholderia cepacia complex biofilms

Anne-Sophie MessiaenKatrien ForierHans NelisKevin BraeckmansTom Coenye

A1 Journal Article in PLOS ONE

Transport of nanoparticles in cystic fibrosis sputum and bacterial biofilms by single-particle tracking microscopy

Katrien ForierAnne-Sophie MessiaenKoen RaemdonckHendrik DeschoutJoanna RejmanFrans De BaetsHans NelisStefaan De SmedtJo DemeesterTom Coenye et al.

A1 Journal Article in NANOMEDICINE

Turning a frown upside down: exploiting nanoparticle toxicity for anticancer therapy

Stefaan SoenenJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in NANO TODAY

2012

An ex vivo assay to measure the mobility inside the eye of nanomedicines for retinal gene therapy

Thomas MartensDries VercauterenKatrien ForierHendrik DeschoutKatrien RemautJo DemeesterStefaan De SmedtKevin Braeckmans

Cytotoxic effects of gold nanoparticles : a multiparametric study

Stefaan SoenenBella ManshianJosé María MontenegroFaheem AminBjörn MeermannToke ThironMaria CornelissenFrank VanhaeckeShareen DoakWolfgang J Parak et al.

A1 Journal Article in ACS NANO

Detection and characterization of subvisible aggregates of monoclonal lgG in serum

Vasco FilipeRobert PooleOlubukayo OyetayoKevin BraeckmansWim Jiskoot

A1 Journal Article in PHARMACEUTICAL RESEARCH

Development of a method for the measurement of primary cilia length in 3D

Taryn SaggeseAlistair A YoungChaobo HuangKevin BraeckmansSusan R McGlashan

A2 Journal Article in CILIA

Elucidating the pre- and post-nuclear intracellular processing of 1,4-dihydropyridine based gene delivery carriers

Zanna HyvönenVesa HämäläinenMarika RuponenBart LucasJoanna RejmanDries VercauterenJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Immobilization of pseudorabies virus in porcine tracheal respiratory mucus revealed by single particle tracking

Xiaoyun YangKatrien ForierLennert SteukersSandra Van VlierberghePeter DubruelKevin BraeckmansSarah GlorieuxHans Nauwynck

A1 Journal Article in PLOS ONE

In search for cross-reactivity to immunophenotype equine mesenchymal stromal cells by multicolor flow cytometry

Catharina De SchauwerSofie PiepersGerlinde Van de WalleKristel DemeyereMaarten HoogewijsJan GovaereKevin BraeckmansAnn Van SoomEvelyne Meyer

A1 Journal Article in CYTOMETRY PART A

Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis

Nathalie SymensStefaan SoenenJoanna RejmanKevin BraeckmansStefaan De SmedtKatrien Remaut

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Investigating the toxic effects of iron oxide nanoparticles

Stefaan SoenenMarcel De CuyperStefaan De SmedtKevin Braeckmans

A1 Journal Article in Methods in Enzymology

Limitations and caveats of magnetic cell labeling using transfection agent complexed iron oxide nanoparticles

Stefaan SoenenStefaan De SmedtKevin Braeckmans

A1 Journal Article in CONTRAST MEDIA & MOLECULAR IMAGING

Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design

Kevin BuyensStefaan De SmedtKevin BraeckmansJo DemeesterLiesbeth PeetersLeo A van GrunsvenXavier de Mollerat du JeuRupa SawantVladimir TorchilinKatarina Farkasova et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

On the cellular processing of non-viral nanomedicines for nucleic acid delivery: mechanisms and methods

Dries VercauterenJoanna RejmanThomas MartensJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat

M. Al SorajL. HeKaren PeynshaertJ. CousaertDries VercauterenKevin BraeckmansStefaan De SmedtArwin T. Jones

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Spatiotemporal visualization of subcellular dynamics of carbon nanotubes

Maged F SeragKevin BraeckmansSatoshi HabuchiNoritada KajiAlberto BiancoYoshinobu Baba

A1 Journal Article in NANO LETTERS

The cytotoxic effects of polymer-coated quantum dots and restrictions for live cell applications

Stefaan SoenenJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in BIOMATERIALS

The influence of movement on the localization precision of sub-resolution particles in fluorescence microscopy

Hendrik DeschoutKristiaan NeytsKevin Braeckmans

A1 Journal Article in JOURNAL OF BIOPHOTONICS

2011

A functional platform for controlled subcellular distribution of carbon nanotubes

Maged F SeragNoritada KajiEnrica VenturelliYukihiro OkamotoKazuyoshi TerasakaManabu TokeshiHajime MizukamiKevin BraeckmansAlberto BiancoYoshinobu Baba

A1 Journal Article in ACS NANO

An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes

BJ CrielaardA YousefiJP SchillemansC VermehrenKevin BuyensKevin BraeckmansTwan LammersG Storm

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation

Stefaan SoenenPilar Rivera-GilJosé-María MontenegroWolfgang J ParakStefaan De SmedtKevin Braeckmans

A1 Journal Article in NANO TODAY

Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

Dries VercauterenHendrik DeschoutKatrien RemautJohan FJ EngbersenArwyn T JonesJo DemeesterStefaan De SmedtKevin Braeckmans

A1 Journal Article in ACS NANO

Effect of a low concentration of a cationic steroid antibiotic (CSA-13) on the formation of a biofilm by Pseudomonas aeruginosa

C NagantY FengBart LucasKevin BraeckmansP SavageJP Dehaye

A1 Journal Article in JOURNAL OF APPLIED MICROBIOLOGY

Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes

Dries VercauterenMartin PiestLeonardus J van der AAMonerah Al SorajArwyn T JonesJohan FJ EngbersenStefaan De SmedtKevin Braeckmans

A1 Journal Article in BIOMATERIALS

Fluorescence recovery after photobleaching on the confocal laser-scanning microscope: generalized model without restriction on the size of the photobleached disk

Nick SmisdomKevin BraeckmansHendrik DeschoutMartin vandeVenJean-Michel RigoStefaan De SmedtMarcel Ameloot

A1 Journal Article in JOURNAL OF BIOMEDICAL OPTICS

Fluorescence single particle tracking for sizing of nanoparticles in undiluted biological fluids

Kevin BraeckmansKevin BuyensWim Bouquet-GeerardynChris VervaetPhilippe JoyeFilip De VosLaurent PlawinskiLoïc DoeuvreEduardo Angles-CanoNiek Sanders et al.

Fluorescence single particle tracking for the characterization of submicron protein aggregates in biological fluids and complex formulations

Vasco FilipeRobert PooleMarika KutscherKatrien ForierKevin BraeckmansWim Jiskoot

A1 Journal Article in PHARMACEUTICAL RESEARCH

Hemocompatibility of siRNA loaded dextran nanogels

Broes NaeyeHendrik DeschoutMagnus RodingMats RudemoJoris DelangheKatrien DevreeseJo DemeesterKevin BraeckmansStefaan De SmedtKoen Raemdonck

A1 Journal Article in BIOMATERIALS

Measuring absolute number concentrations of nanoparticles using single-particle tracking

Magnus RödingHendrik DeschoutKevin BraeckmansMats Rudemo

A1 Journal Article in PHYSICAL REVIEW E

MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes

Stefaan SoenenSimon De MeyerTom DresselaersGreetje Vande VeldeInge PareynKevin BraeckmansMarcel De CuyperUwe HimmelreichKaren Vanhoorelbeke

A1 Journal Article in BIOMATERIALS

On the cellular processing of nanomedicines for retinal gene therapy and their suitability for intravitreal injections

Dries VercauterenKevin BraeckmansStefaan De Smedt

Protein macromonomers containing reduction-sensitive linkers for covalent immobilization and glutathione triggered release from dextran hydrogels

Ellen VerheyenSteffen van der WalHendrik DeschoutKevin BraeckmansStefaan De SmedtArjan BarendregtWim E HenninkCornelus F van Nostrum

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Stimuli-responsive electrospun fibers and their applications

Chaobo HuangStefaan SoenenJoanna RejmanBart LucasKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

2010

Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles

Kevin BraeckmansKevin BuyensBroes NaeyeDries VercauterenHendrik DeschoutKoen RaemdonckKatrien RemautNiek SandersJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Colour-coded microcarriers: made to move

Kevin BraeckmansStefaan De Smedt

Fungicidal activity of miconazole against Candida spp. biofilms

Davy VandenboschKevin BraeckmansHans NelisTom Coenye

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influence of temperature, oxygen and bacterial strain identity on the association of Campylobacter jejuni with Acanthamoeba castellanii

Julie BaréKoen SabbeSharon HuwsDries VercauterenKevin BraeckmansIneke van GrembergheHerman FavoreelKurt Houf

A1 Journal Article in FEMS MICROBIOLOGY ECOLOGY

Photopolymerized thermosensitive poly(HPMAlactate)-PEG-based hydrogels : effect of network design on mechanical properties, degradation, and release behavior

Roberta CensiTina VermondenHendrik DeschoutKevin BraeckmansPiera di MartinoStefaan De SmedtCornelus F van NostrumWim E Hennink

A1 Journal Article in BIOMACROMOLECULES

Single particle tracking

Kevin BraeckmansDries VercauterenJo DemeesterStefaan De Smedt

Bookchapter in Nanoscopy and multidimensional optical fluorescence microscopy

siRNA containing nanoparticles: stability of encapsulation and particle size

Kevin BuyensKevin BraeckmansJo DemeesterStefaan De SmedtNiek Sanders

Sizing nanomatter in biological fluids by fluorescence single particle tracking

Kevin BraeckmansKevin BuyensWim Bouquet-GeerardynChris VervaetPhilippe JoyeFilip De VosLaurent PlawinskiLoic DoeuvreEduardo Angles-CanoNiek Sanders et al.

A1 Journal Article in NANO LETTERS

Straightforward FRAP for quantitative diffusion measurements with a laser scanning microscope

Hendrik DeschoutJoel HagmanSophia FranssonJenny JonassonMats RudemoNiklas LorénKevin Braeckmans

A1 Journal Article in OPTICS EXPRESS

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls

Dries VercauterenRoosmarijn VandenbrouckeArwyn T JonesJoanna RejmanJo DemeesterStefaan De SmedtNiek SandersKevin Braeckmans

A1 Journal Article in MOLECULAR THERAPY

Transport and delivery of antimicrobial agents in Burkholderia biofilms

Katrien ForierAnne-Sophie MessiaenTom CoenyeHans NelisShari CelenSerge Van CalenberghStefaan De SmedtJo DemeesterKevin Braeckmans

Unbreakable codes in electrospun fibers : digitally encoded polymers to stop medicine counterfeiting

Chaobo HuangBart LucasChris VervaetKevin BraeckmansSerge Van CalenberghIzet KaralicMado VandewoestyneDieter DeforceJo DemeesterStefaan De Smedt

A1 Journal Article in ADVANCED MATERIALS

Unbreakable codes in electrospun fibers to stop medicine counterfeiting

Chaobo HuangBart LucasChris VervaetKevin BraeckmansSerge Van CalenberghIzet KaralicMado VandewoestyneDieter DeforceJo DemeesterStefaan De Smedt

2009

Extracellular barriers in respiratory gene therapy

Niek SandersCarsten RudolphKevin BraeckmansStefaan De SmedtJo Demeester

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Photopolymerized thermosensitive hydrogels for tailorable diffusion-controlled protein delivery

R CensiT VermondenMJ van SteenbergenHendrik DeschoutKevin BraeckmansStefaan De SmedtCF van NostrumP di MartinoWE Hennink

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Protein-Release Behavior of Self-Assembled PEG-beta-Cyclodextrin/PEG-Cholesterol Hydrogels

F van de ManakkerKevin BraeckmansN el MorabitStefaan De SmedtCF van NostrumWE Hennink

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Stable long-term intracellular labelling with fluorescently tagged cationic magnetoliposomes

Stefaan JH SoenenDries VercauterenKevin BraeckmansWim NoppeStefaan De SmedtMarcel De Cuyper

A1 Journal Article in CHEMBIOCHEM

The role of nanoparticle concentration-dependent induction of cellular stress in the internalization of non-toxic cationic magnetoliposomes

Stefaan SoenenEszter IllyesDries VercauterenKevin BraeckmansZsuzsa MajerStefaan De SmedtMarcel De Cuyper

A1 Journal Article in BIOMATERIALS

2008

A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum

Kevin BuyensBart LucasKoen RaemdonckKevin BraeckmansJ VERCAMMENJ HENDRIXY ENGELBORGHSStefaan De SmedtNiek Sanders

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

A new FRAP/FRAPa method for three-dimensional diffusion measurements based on multiphoton excitation microscopy

Davide MazzaKevin BraeckmansFrancesca CellaIlaria TestaDries VercauterenJo DemeesterStefaan De SmedtAlberto Diaspro

A1 Journal Article in BIOPHYSICAL JOURNAL

Advanced fluorescence microscopy methods illuminate the transfection pathway

Stefaan De SmedtKevin BraeckmansDries VercauterenJo Demeester

Evaluation of encoded layer-by-layer coated microparticles as protease sensors

Barbara StubbeKris GevaertStefaan DerveauxKevin BraeckmansBruno De GeestMarc GoethalsJoël VandekerckhoveJo DemeesterStefaan De Smedt

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Opportunities for digitally encoded microcarriers in pharmacy and cell-based assays

Farzaneh FayazpourBart LucasN HUYGEBAERTKevin BraeckmansStefaan DerveauxRoosmarijn VandenbrouckeJean Paul RemonJo DemeesterChris VervaetStefaan De Smedt

Synergism between particle-based multiplexing and microfluidics technologies may bring diagnostics closer to the patient

Stefaan DerveauxBarbara StubbeKevin BraeckmansC ROELANTK SATOJo DemeesterStefaan De Smedt

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Water-soluble monofunctional perylene and terrylene dyes: Powerful labels for single-enzyme tracking

K PENEVAG MIHOVF NOLDES ROCHAJ HOTTAKevin BraeckmansJ HOFKENSH UJI-IA HERRMANNK MULLEN

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2007

Brn-3a suppresses pseudorabies virus-induced cell death in sensory neurons

K GEENENHans NauwynckNick De ReggeKevin BraeckmansHerman Favoreel

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy?

Katrien RemautBart LucasKoen RaemdonckKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Cell uptake, cytoplasmic diffusion and nuclear access of a 6.5 nm diameter dendrimer

P RUENRAROENGSAKKT AL-JAMALN HARTELLKevin BraeckmansStefaan De SmedtAT FLORENCE

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Digitally encoded drug tablets to combat counterfeiting

Farzaneh FayazpourBart LucasN HUYGHEBAERTKevin BraeckmansStefaan DerveauxBG STUBBEJean Paul RemonJo DemeesterChris VervaetStefaan De Smedt

A1 Journal Article in ADVANCED MATERIALS

Influence of free chains on the swelling pressure of PEG-HEMA and dex-HEMA hydrogels

Tinneke Van ThienenF HORKAYKevin BraeckmansBG STUBBEJo DemeesterStefaan De Smedt

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples

Kevin BraeckmansKatrien RemautRoosmarijn VandenbrouckeBart LucasStefaan De SmedtJo Demeester

A1 Journal Article in BIOPHYSICAL JOURNAL

Multifunctional layer-by-layer coating of digitally encoded microparticles

Stefaan DerveauxBruno De GeestC ROELANTKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in LANGMUIR

Nucleic acid delivery: Where material sciences and bio-sciences meet

Katrien RemautNiek SandersBruno De GeestKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in MATERIALS SCIENCE & ENGINEERING R-REPORTS

Pegylation of liposomes favours the endosornal degradation of the delivered phosphodiester oligonucleotides

Katrien RemautBart LucasKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine

Katrien RemautBart LucasKoen RaemdonckKevin BraeckmansJo DemeesterStefaan De Smedt

A1 Journal Article in BIOMACROMOLECULES

2006

Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation- a case study for fluorescein

Kevin BraeckmansBarbara StubbeKatrien RemautJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF BIOMEDICAL OPTICS

Characterization of diffusion of macromolecules in konjac glucomannan solutions and gels by fluorescence recovery after photobleaching technique

F ALVAREZ-MANCENIDOKevin BraeckmansStefaan De SmedtJo DemeesterM LANDINR MARTINEZ-PACHECO

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Characterization of the mode of incorporation of lipophilic compounds in solid dispersions at the nanoscale using fluorescence resonance energy transfer (FRET)

DJ VAN DROOGEKevin BraeckmansWLJ HINRICHSKatrien RemautStefaan De SmedtHW FRIJLINK

A1 Journal Article in MACROMOLECULAR RAPID COMMUNICATIONS

Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick?

Katrien RemautBart LucasKevin BraeckmansNiek SandersJo DemeesterStefaan De Smedt

A1 Journal Article in BIOCHEMISTRY

The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying

WLJ HINRICHSFA MANCENIDONiek SandersKevin BraeckmansStefaan De SmedtJo DemeesterHW FRIJLINK

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

The transport of nanosized gene carriers unraveled by live-cell imaging

R BAUSINGERK VON GERSDORFFKevin BraeckmansM OGRISE WAGNERC BRAUCHLEA ZUMBUSCH

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2005

Fluorescence energy transfer to study the degradation of double-labeled oligonucleotides

Katrien RemautBart LucasKevin BraeckmansNiek SandersStefaan De SmedtJo Demeester

FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery

Katrien RemautBart LucasKevin BraeckmansNiek SandersStefaan De SmedtJo Demeester

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching

SR VAN TOMMEBruno De GeestKevin BraeckmansStefaan De SmedtF SIEPMANNJ SIEPMANNCF VAN NOSTRUMWE HENNINK

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Protection of oligonucleotides against nucleases by pegylated and non-pegylated liposomes as studied by fluorescence correlation spectroscopy

Katrien RemautBart LucasKevin BraeckmansNiek SandersJo DemeesterStefaan De Smedt

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Self-rupturing microcapsules

Bruno De GeestC DEJUGNATGB SUKHORUKOVKevin BraeckmansStefaan De SmedtJo Demeester

A1 Journal Article in ADVANCED MATERIALS

Studying biophysical barriers to DNA delivery by advanced light microscopy

Stefaan De SmedtKatrien RemautBart LucasKevin BraeckmansNiek SandersJo Demeester

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fluorescence fluctuation spectroscopy and confocal imaging

Bart LucasKatrien RemautNiek SandersKevin BraeckmansStefaan De SmedtJo Demeester

A1 Journal Article in BIOCHEMISTRY

Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells

Bart LucasKatrien RemautNiek SandersKevin BraeckmansStefaan De SmedtJo Demeester

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Vitreous: a barrier to nonviral ocular gene therapy

Liesbeth PeetersNiek SandersKevin BraeckmansKoen BousseryJohan Van de VoordeStefaan De SmedtJo Demeester

A1 Journal Article in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

2004

Photobleaching with the confocal laser scanning microscope for mobility measurements and the encoding of microbeads

Kevin BraeckmansJ DemeesterS De Smedt

Studying pegylated DNA complexes by dual color fluorescence fluctuation spectroscopy

Bart LucasKatrien RemautKevin BraeckmansJurgen HaustraeteStefaan De SmedtJo Demeester

A1 Journal Article in MACROMOLECULES

2003

Encoding microcarriers by spatial selective photobleaching

Kevin BraeckmansStefaan De SmedtC ROELANTM LEBLANSRomain PauwelsJo Demeester

A1 Journal Article in NATURE MATERIALS

Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope

Kevin BraeckmansLiesbeth PeetersNiek SandersStefaan De SmedtJo Demeester

A1 Journal Article in BIOPHYSICAL JOURNAL

2002

Encoding microcarriers : present and future technologies

Kevin BraeckmansStefaan De SmedtMarc LeblansRomain PauwelsJo Demeester

A1 Journal Article in NATURE REVIEWS DRUG DISCOVERY

Swelling pressure observations on degrading dex-HEMA hydrogels.

Barbara StubbeKevin BraeckmansF HORKAYWE HENNINKStefaan De SmedtJo Demeester

A1 Journal Article in MACROMOLECULES