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Onderzoeker
Jonas Steenbrugge
Profiel
Projecten
Publicaties
Activiteiten
Prijzen & Erkenningen
25
Resultaten
2023
Chitinase 3-like 1 stimulates macrophage-mediated lymphatic remodeling in triple-negative breast cancer
Jonas Steenbrugge
Robbe Salembier
Alan M. Elder
Evelyne Meyer
Traci R. Lyons
U
Conferentie
2023
2022
Chitin immunomodulation stimulates anti-PD-1 therapy in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Julie Bellemans
Kristel Demeyere
Niek Sanders
Evelyne Meyer
U
Conferentie
2022
One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Julie Bellemans
Niels Vander Elst
Kristel Demeyere
Josephine De Vliegher
Timothy Perera
Olivier De Wever
Wim Van Den Broeck
Ward De Spiegelaere
Niek Sanders
et al.
A1
Artikel in een tijdschrift
in
ONCOIMMUNOLOGY
2022
One cisplatin dose suffices to maintain anti-tumor immunity and enhances anti-PD-1 efficacy in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Julie Bellemans
Niels Vander Elst
Kristel Demeyere
Niek Sanders
Evelyne Meyer
C3
Conferentie
2022
Progression of canine mammary tumors is associated with an immunosuppressed microenvironment
Jonas Steenbrugge
Julie Bellemans
Lennert Heirman
Aurelie De Roover
Kristel Demeyere
Hilde De Rooster
Evelyne Meyer
C3
Conferentie
2022
2021
Immunomodulation by cisplatin chemotherapy in an immunocompetent intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Josephine De Vliegher
Annegret Van der Aa
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
C3
Conferentie
2021
OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
A1
Artikel in een tijdschrift
in
NPJ BREAST CANCER
2021
Splenic immunomodulatory effects of cisplatin in an immunocompetent intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Josephine De Vliegher
Annegret Van der Aa
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
C3
Conferentie
2021
Unexpected effects of a selective and potent c-MET inhibitor in an immunocompetent intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Annegret Van der Aa
Eric Ciamporcero
Timothy Perera
Evelyne Meyer
C3
Conferentie
2021
2020
Enterobactin deficiency in a coliform mastitis isolate decreases its fitness in a murine model : a preliminary host-pathogen interaction study
Niels Vander Elst
Koen Breyne
Jonas Steenbrugge
Amanda Jane Gibson
David George Emslie Smith
Pierre Germon
Dirk Werling
Evelyne Meyer
A1
Artikel in een tijdschrift
in
FRONTIERS IN VETERINARY SCIENCE
2020
Splenic hematopoietic and stromal cells in cancer progression
Jonas Steenbrugge
Emiel De Jaeghere
Evelyne Meyer
Hannelore Denys
Olivier De Wever
A1
Artikel in een tijdschrift
in
CANCER RESEARCH
2020
2019
Characterization of an immunocompetent intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge
Evelyne Meyer
Steven Van Laere
Proefschrift
2019
Comparative immune profiling of an aggressive 4T1-based versus a non-aggressive Py230-based intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Steven Van Laere
Evelyne Meyer
C3
Conferentie
2019
Comparative profiling of metastatic 4T1- vs. non-metastatic Py230-based mammary tumors in an intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Luc Dirix
Steven Van Laere
Evelyne Meyer
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2019
Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models
Yves Depetter
Silke Geurs
Rob De Vreese
Sophie Goethals
Elien Vandoorn
Alien Laevens
Jonas Steenbrugge
Evelyne Meyer
Pascal de Tullio
Marc Bracke
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CANCER
2019
2018
Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge
Koen Breyne
Kristel Demeyere
Olivier De Wever
Niek Sanders
Wim Van Den Broeck
Cecile Colpaert
Peter Vermeulen
Steven Van Laere
Evelyne Meyer
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
2018
Immunomodulation of host chitinase 3-like 1 during a mammary pathogenic Escherichia coli infection
Koen Breyne
Jonas Steenbrugge
Kristel Demeyere
Chun Geun Lee
Jack A Elias
Wolfram Petzl
David GE Smith
Pierre Germon
Evelyne Meyer
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2018
Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis
Robin Boiy
Jonas Steenbrugge
Jan Van Deun
An Hendrix
Evelyne Meyer
Olivier De Wever
A1
Artikel in een tijdschrift
in
CLINICAL & EXPERIMENTAL METASTASIS
2018
Tumor immune profiling and host NF-kappaB activity assessment in a novel Py230-based intraductal model for triple-negative breast cancer
Jonas Steenbrugge
Niels Vander Elst
Kristel Demeyere
Niek Sanders
Olivier De Wever
Steven Van Laere
Evelyne Meyer
C3
Conferentie
2018
2017
Efficacy and safety of a bovine-associated Staphylococcus aureus phage cocktail in a murine model of mastitis
Koen Breyne
Ryan W Honaker
Zachary Hobbs
Manuela Richter
Maciej Zaczek
Taylor Spangler
Jonas Steenbrugge
Rebecca Lu
Anika Kinkhabwala
Bruno Marchon
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN MICROBIOLOGY
2017
Preconditioning with lipopolysaccharide or lipoteichoic acid protects against Staphylococcus aureus mammary infection in mice
Koen Breyne
Jonas Steenbrugge
Kristel Demeyere
Tom Vanden Berghe
Evelyne Meyer
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2017
The crosstalk between macrophages and 4T1 mammary tumor cells promotes metastasis in a novel intraductal model for breast cancer
Jonas Steenbrugge
Koen Breyne
Lore Vander Plancken
Kristel Demeyere
Niek Sanders
Cecile Colpaert
Steven Van Laere
Evelyne Meyer
C3
Conferentie
2017
2016
Chitinase 3-like 1 as breast cancer metastasis biomarker for differential tumor progression in the intraductal versus the fat pad preclinical model
Jonas Steenbrugge
Koen Breyne
Sofie Denies
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Niek Sanders
Evelyne Meyer
C3
Conferentie
2016
Comparison of the adipose and luminal mammary gland compartment as orthotopic inoculation sites in a 4T1-based immunocompetent preclinical model for triple-negative breast cancer
Jonas Steenbrugge
Koen Breyne
Sofie Denies
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Peter Vermeulen
Steven Van Laere
Niek Sanders
Evelyne Meyer
A1
Artikel in een tijdschrift
in
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
2016
2015
Is intraductal inoculation of tumour cells a more relevant in vivo model for immune-competent breast cancer metastasis than the classical fat pad model?
Koen Breyne
Sofie Denies
Jonas Steenbrugge
Melissa Dekimpe
Kristel Demeyere
Olivier De Wever
Niek Sanders
Evelyne Meyer
C3
Conferentie
2015