Research Explorer

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Researcher

Jitesh Neupane

Publications & Research Data

Awards & Distinctions

25 Results

2018

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background

Sabitri GhimireMargot Van der JeughtJitesh NeupaneMatthias S RoostJasper AnckaertMina PopovicFilip Van NieuwerburghPieter MestdaghJo VandesompeleDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes

Yuechao LuDavina BonteMinerva Ferrer BuitragoMina PopovicJitesh NeupaneMargot Van der JeughtLuc LeybaertPetra De SutterBjörn Heindryckx

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes

Yuechao LuMinerva Ferrer BuitragoMina PopovicJitesh NeupaneWinnok De VosSylvie LiermanEtienne Van den AbbeelMargot Van der JeughtDimitra NikiforakiPetra De Sutter et al.

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels

Y LuR ReddyMinerva Ferrer BuitragoMargot Van der JeughtJitesh NeupaneWinnok De VosEtienne Van den AbbeelSylvie LiermanPetra De SutterBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION OPEN

2016

Inhibition of Rho-associated protein kinase (ROCK) in mouse embryos affects trophectoderm formation and blastocyst development, but still allows subsequent stem cell derivation

Sabitri GhimireMargot Van der JeughtJitesh NeupanePetra De SutterBjörn Heindryckx

2015

Are TrpV3 channels present in human oocytes to mediate strontium-induced artificial activation?

Yuechao LuMinerva Ferrer BuitragoJitesh NeupaneW. H. De VosEtienne Van den AbbeelMargot Van der JeughtPetra De SutterBjörn Heindryckx

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneSabitri GhimireMado VandewoestyneYuechao LuJan GerrisRudy Van CosterTom DerooDieter DeforceStijn VansteelandtPetra De Sutter et al.

A1 Journal Article in CELL REPORTS

Derivation conditions affect pluripotency and differentiation propensity of mouse embryonic stem cells

Sabitri GhimireMargot Van der JeughtJitesh NeupaneFilip Van NieuwerburghDieter DeforceSusana Marina Chuva de Sousa LopesPetra De SutterBjörn Heindryckx

Diagnostic and therapeutic approaches to prevent the transmission of heritable mitochondrial diseases

Jitesh NeupanePetra De SutterDieter Deforce

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

Sabitri GhimireBjörn HeindryckxMargot Van der JeughtJitesh NeupaneThomas O'LearySylvie LiermanWinnok De VosSusana Marina Chuva de Sousa LopesTom DerooPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2014

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianSylvie LiermanRudy Van CosterJan GerrisTom Deroo et al.

A1 Journal Article in HUMAN REPRODUCTION

Assessment of cellular heterogeneity in the level of mitochondrial DNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneBjörn HeindryckxMado VandewoestyneSabitri GhimireYuechao LuRudy Van CosterDieter DeforceTom DerooPetra De Sutter

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

Jitesh NeupaneMado VandewoestyneSabitri GhimireYuechao LuChen QianRudy Van CosterJan GerrisTom DerooDieter DeforcePetra De Sutter et al.

A1 Journal Article in MITOCHONDRION

Effect of ionomycin and calcium in the culture medium on the calcium releasing pattern of mouse oocytes and their subsequent embryonic development

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneChen QianWinnok De VosJP OzilTom DerooPetra De SutterBjörn Heindryckx

Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse

Sabitri GhimireBjörn HeindryckxJitesh NeupaneDieter DeforceTom DerooPetra De Sutter

Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis

Björn HeindryckxJitesh NeupaneMado VandewoestyneCHRISTODOULOS CHRISTODOULOUYens JackersJan GerrisEtienne Van den AbbeelRudy Van CosterDieter DeforcePetra De Sutter

A1 Journal Article in MITOCHONDRION

2013

Evaluation of calcium machinery in a meiosis defect mouse model

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneWinnok De VosSylvie LiermanTom DerooBjörn HeindryckxPetra De Sutter

Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxTom DerooYuechao LuSabitri GhimireSylvie LiermanChen QianDieter DeforcePetra De Sutter

2012

Dose-dependent effect of inhibition of the transforming growth factor beta pathway during early mouse lineage segregation

Sabitri GhimireMargot Van der JeughtJitesh NeupaneSylvie LiermanThomas O'LearySusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

Poor correlation between polar bodies and blastomere mutation load in a patient with m.3243A>G tRNALeu(UUR) point mutation

Mado VandewoestyneBjörn HeindryckxStefanie De GheselleTrees LepezJitesh NeupaneJan GerrisRudy Van CosterPetra De SutterDieter Deforce

A1 Journal Article in MITOCHONDRION

Promuclear transfer in mice yields minimal mitochondrial DNA carry-over

Mado VandewoestyneJitesh NeupaneBjörn HeindryckxSylvie LiermanDieter DeforcePetra De Sutter

Pronuclear transfer in mice yields minimal mitochondrial DNA carry-over

Mado VandewoestyneJitesh NeupaneBjörn HeindryckxSylvie LiermanDieter DeforcePetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianDieter DeforcePetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuSylvie LiermanChen QianDieter DeforcePetra De Sutter

The effect of oocyte aging on the calcium oscillations and embryo development of in vivo and in vitro matured oocytes

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneBjörn HeindryckxPetra De Sutter