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Researcher
Isabel Leroux-Roels
Profile
Projects
Publications
Activities
49
Results
2022
A randomized, double-blind, placebo-controlled, dose-escalating phase I trial to evaluate safety and immunogenicity of a plant-produced, bivalent, recombinant norovirus-like particle vaccine
Isabel Leroux-Roels
Jasper Joye
Bart Jacobs
Yorick Janssens
Gwenn Waerlop
Geert Leroux-Roels
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD) : a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial
Isabel Leroux-Roels
A1
Journal Article
in
LANCET INFECTIOUS DISEASES
2022
Implementation of the Infection Risk Scan (IRIS) in nine hospitals in the Belgian-Dutch border region (i-4-1-Health project)
Isabel Leroux-Roels
A1
Journal Article
in
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
2022
Randomized, double-blind, reference-controlled, phase 2a study evaluating the immunogenicity and safety of OVX836, a nucleoprotein-based influenza vaccine
Isabel Leroux-Roels
Gwenn Waerlop
Catherine Maes
Geert Leroux-Roels
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
The role of cell-mediated immunity against influenza and its implications for vaccine evaluation
Yorick Janssens
Jasper Joye
Gwenn Waerlop
Frédéric Clement
Geert Leroux-Roels
Isabel Leroux-Roels
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
2021
A new fully liquid presentation of MenACWY-CRM conjugate vaccine : results from a multicentre, randomised, controlled, observer-blind study
Isabel Leroux-Roels
A1
Journal Article
in
VACCINE
2021
Combined oropharyngeal/nasal swab is equivalent to nasopharyngeal sampling for SARS-CoV-2 diagnostic PCR
Tania Desmet
Peter De Paepe
Jerina Boelens
Liselotte Coorevits
Elizaveta Padalko
Stien Vandendriessche
Isabel Leroux-Roels
Annelies Aerssens
Steven Callens
Eva Van Braeckel
Frank Vermassen
Bruno Verhasselt
A1
Journal Article
in
BMC MICROBIOLOGY
2021
ESBL-producing, carbapenem- and ciprofloxacin-resistant Escherichia coli in Belgian and Dutch broiler and pig farms : a cross-sectional and cross-border study
Moniek Ringenier
Jeroen Dewulf
Liselotte Coorevits
Isabel Leroux-Roels
Merel Postma
A1
Journal Article
in
ANTIBIOTICS-BASEL
2021
Immunogenicity and safety of a 3-antigen hepatitis B vaccine vs a single-antigen hepatitis B vaccine : a phase 3 randomized clinical trial
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
JAMA NETWORK OPEN
2021
Immunogenicity and safety of a quadrivalent high-dose inactivated influenza vaccine compared with a standard-dose quadrivalent influenza vaccine in healthy people aged 60 years or older : a randomized Phase III trial
Isabel Leroux-Roels
A1
Journal Article
in
HUMAN VACCINES & IMMUNOTHERAPEUTICS
2021
Proof-of-concept of a low-dose unmodified mRNA-based rabies vaccine formulated with lipid nanoparticles in human volunteers : a phase 1 trial
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2021
Safety and immunogenicity of a new Sabin inactivated poliovirus vaccine candidate produced on the PER.C6 (R) cell-line : a phase 1 randomized controlled trial in adults
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
HUMAN VACCINES & IMMUNOTHERAPEUTICS
2021
Safety and immunogenicity of an mRNA-lipid nanoparticle vaccine candidate against SARS-CoV-2 : a phase 1 randomized clinical trial
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
WIENER KLINISCHE WOCHENSCHRIFT
2021
Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults : two clinical trials
Isabel Leroux-Roels
Annelies Aerssens
Geert Leroux-Roels
A1
Journal Article
in
LANCET
2021
2020
Detection of H1 swine influenza a virus antibodies in human serum samples by age group
Elien Vandoorn
Isabel Leroux-Roels
Geert Leroux-Roels
Anna Parys
Kristien Van Reeth
A1
Journal Article
in
EMERGING INFECTIOUS DISEASES
2020
Multidrug-resistant bacteria in ICU : fact or myth
Jan De Waele
Jerina Boelens
Isabel Leroux-Roels
A1
Journal Article
in
CURRENT OPINION IN ANESTHESIOLOGY
2020
Persistence of vaccine-elicited immune response up to 14 years post-HIV gp120-NefTat/AS01(B) vaccination
Annelies Aerssens
Geert Leroux-Roels
Isabel Leroux-Roels
A1
Journal Article
in
VACCINE
2020
Toilet drain water as a potential source of hospital room-to-room transmission of carbapenemase-producing Klebsiella pneumoniae
Hannelore Hamerlinck
Jerina Boelens
Bruno Verhasselt
Isabel Leroux-Roels
A1
Journal Article
in
JOURNAL OF HOSPITAL INFECTION
2020
2019
A recurrent and transesophageal echocardiography-associated outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae complex in cardiac surgery patients
Tom Van Maerken
Liselotte Coorevits
Stefaan Bouchez
Harlinde Peperstraete
Bruno Verhasselt
Jerina Boelens
Isabel Leroux-Roels
A1
Journal Article
in
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
2019
Nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients : causes and consequences
Tom Van Maerken
Isabel Leroux-Roels
A1
Journal Article
in
JOURNAL OF HOSPITAL INFECTION
2019
2018
Improving timelines in reporting results from positive blood cultures : simulation of impact of rapid identification on therapy on a real-life cohort
Liselotte Coorevits
Isabel Leroux-Roels
Geert Claeys
Bruno Verhasselt
Jerina Boelens
A1
Journal Article
in
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2018
2017
Surveillance of endoscopes : comparison of different sampling techniques
Martine De Vos
Bruno Verhasselt
Jerina Boelens
Isabel Leroux-Roels
A1
Journal Article
in
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2017
2016
Antibody persistence and booster responses to split-virion H5N1 avian influenza vaccine in young and elderly adults
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
PLOS ONE
2016
Caught on tape
Isabel Leroux-Roels
Pieter Hindryckx
Editorial material
2016
2015
Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: randomised, controlled trials
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2015
Influenza vaccines: where do we stand? Where do we go? A bumpy but steady road upwards
Isabel Leroux-Roels
Editorial material
2015
2014
Bordetella pertussis seroprevalence in Belgian adults aged 20-39 years, 2012
Isabel Leroux-Roels
A1
Journal Article
in
EPIDEMIOLOGY AND INFECTION
2014
Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines : randomized, double-blind study in malaria-naïve adults
Geert Leroux-Roels
Isabel Leroux-Roels
Frédéric Clement
A1
Journal Article
in
HUMAN VACCINES & IMMUNOTHERAPEUTICS
2014
Implementation of a multidisciplinary infectious diseases team in a tertiary hospital within an Antimicrobial Stewardship Program
Franky Buyle
Jerina Boelens
Steven Callens
Geert Claeys
Isabel Leroux-Roels
Hugo Robays
Linos Vandekerckhove
Karen Vermis
Dirk Vogelaers
A1
Journal Article
in
ACTA CLINICA BELGICA
2014
Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
Jan De Waele
Sofie Carrette
Mieke Carlier
Veronique Stove
Jerina Boelens
Geert Claeys
Isabel Leroux-Roels
Eric Hoste
Pieter Depuydt
Johan Decruyenaere
Alain Verstraete
A1
Journal Article
in
INTENSIVE CARE MEDICINE
2014
Validity analysis of a unique infection surveillance system in the intensive care unit by analysis of a data warehouse built through a workflow-integrated software application
Liesbet De Bus
Bram Gadeyne
Isabel Leroux-Roels
Geert Claeys
Kristof Steurbaut
Dominique Benoit
Filip De Turck
Johan Decruyenaere
Pieter Depuydt
A1
Journal Article
in
JOURNAL OF HOSPITAL INFECTION
2014
2013
Characeteristics and outcome of neonates with a healthcare-associated bloodstream infection in a NICU over a 10-year period (2002-2011)
Evelien Verstraete
Geert Claeys
Isabel Leroux-Roels
Dirk Vogelaers
Piet Vanhaesebrouck
Stijn Blot
C3
Conference
2013
Clinical evaluation to confirm the manufacturing consistency of three lots of an adjuvanted glycoprotein D genital herpes vaccine in healthy seronegative pre-teen and adolescent girls: a phase III multi-center double-blind randomized trial
Geert Leroux-Roels
Isabel Leroux-Roels
A2
Journal Article
in
TRIALS IN VACCINOLOGY
2013
Edwardsiella tarda sepsis in a live-stranded sperm whale (Physeter macrocephalus)
Piet Cools
Guido Lopes dos Santos Santiago
Geert Claeys
Jerina Boelens
Isabel Leroux-Roels
Mario Vaneechoutte
Pieter Deschaght
A1
Journal Article
in
VETERINARY MICROBIOLOGY
2013
Improved CD4⁺ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: a randomized trial
Isabel Leroux-Roels
Frédéric Clement
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2013
Safety and immunogenicity of a glycoprotein D genital herpes vaccine in healthy girls 10-17 years of age: results from a randomised, controlled, double-blind trial
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2013
2012
A phase 1/2 clinical trial evaluating safety and immunogenicity of a varicella zoster glycoprotein E subunit vaccine candidate in young and older adults
Isabel Leroux-Roels
Geert Leroux-Roels
Frédéric Clement
A1
Journal Article
in
JOURNAL OF INFECTIOUS DISEASES
2012
2011
H5N1 influenza vaccine formulated with AS03A induces strong cross-reactive and polyfunctional CD4 T-cell responses
Isabel Leroux-Roels
Frédéric Clement
Geert Leroux-Roels
A1
Journal Article
in
JOURNAL OF CLINICAL IMMUNOLOGY
2011
Head-to-head comparison of pandemic influenza vaccines
Geert Leroux-Roels
Isabel Leroux-Roels
Editorial material
2011
2010
Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02A candidate tuberculosis vaccine in purified protein derivative-negative adults
Isabel Leroux-Roels
Geert Leroux-Roels
Frédéric Clement
A1
Journal Article
in
CLINICAL AND VACCINE IMMUNOLOGY
2010
Inactivated split-virion seasonal influenza vaccine (Fluarix®) : a review of its use in the prevention of seasonal influenza in adults and the elderly
Isabel Leroux-Roels
A1
Journal Article
in
DRUGS
2010
Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study
Isabel Leroux-Roels
Florian Roman
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2010
Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three Adjuvant Systems
Isabel Leroux-Roels
Frédéric Clement
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2010
2009
Current status and progress of prepandemic and pandemic influenza vaccine development
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
EXPERT REVIEW OF VACCINES
2009
Humoral and cellular immune responses to split-virion H5N1 influenza vaccine in young and elderly adults
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2009
2008
An adjuvanted, low-dose, pandemic influenza a (H5N1) vaccine candidate is safe, immunogenic, and induces cross-reactive immune responses in healthy adults
Isabel Leroux-Roels
Sheron Forgus
Geert Leroux-Roels
A1
Journal Article
in
JOURNAL OF INFECTIOUS DISEASES
2008
Broad clade 2 cross-reactive immunity induced by an adjuvanted clade 1 rH5N1 pandemic influenza vaccine
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
PLOS ONE
2008
Seasonal influenza vaccine delivered by intradermal microinjection: A randomised controlled safety and immunogenicity trial in adults
Isabel Leroux-Roels
Geert Leroux-Roels
A1
Journal Article
in
VACCINE
2008
2007
Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial
Isabel Leroux-Roels
Thomas Vanwolleghem
Frédéric Clement
Geert Leroux-Roels
A1
Journal Article
in
LANCET
2007