Research Explorer

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Researcher

Isabel Leroux-Roels

35 Results

2021

Combined oropharyngeal/nasal swab is equivalent to nasopharyngeal sampling for SARS-CoV-2 diagnostic PCR

Tania DesmetPeter De PaepeJerina BoelensLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheIsabel Leroux-RoelsAnnelies AerssensSteven CallensEva Van BraeckelThomas MalfaitFrank VermassenBruno Verhasselt

A1 Journal Article in BMC MICROBIOLOGY

ESBL-producing, carbapenem- and ciprofloxacin-resistant Escherichia coli in Belgian and Dutch broiler and pig farms : a cross-sectional and cross-border study

Sien De KosterMoniek RingenierChristine LammensArjan StegemanTijs TobiasFrancisca VelkersHans VernooijMarjolein Kluytmans-van den BerghJan KluytmansJeroen DewulfHerman GoossensLiselotte CoorevitsIsabel Leroux-RoelsMerel PostmaPascal De Waegemaekerfor the i-4-1-Health Study Group

A1 Journal Article in ANTIBIOTICS-BASEL

2020

Detection of H1 swine influenza a virus antibodies in human serum samples by age group

Elien VandoornIsabel Leroux-RoelsGeert Leroux-RoelsAnna ParysAmy VincentKristien Van Reeth

A1 Journal Article in EMERGING INFECTIOUS DISEASES

Multidrug-resistant bacteria in ICU : fact or myth

Jan De WaeleJerina BoelensIsabel Leroux-Roels

A1 Journal Article in CURRENT OPINION IN ANESTHESIOLOGY

Toilet drain water as a potential source of hospital room-to-room transmission of carbapenemase-producing Klebsiella pneumoniae

Laura HeiremanHannelore HamerlinckS. VandendriesscheJerina BoelensL. CoorevitsE. De BrabanderePascal De WaegemaekerSaskia VerhofstedeK. ClausM. A. Chlebowicz-FlissikowskaJ. W. A. RossenBruno VerhasseltIsabel Leroux-Roels

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

2019

A recurrent and transesophageal echocardiography-associated outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae complex in cardiac surgery patients

Tom Van MaerkenEls De BrabandereAudrey NoëlLiselotte CoorevitsPascal De WaegemaekerRaina AblorhStefaan BouchezIngrid HerckHarlinde PeperstraetePierre BogaertsBruno VerhasseltYouri GlupczynskiJerina BoelensIsabel Leroux-Roels

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

Nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients : causes and consequences

A NoëlC VastradeS DupontM de BarsyTD HuangTom Van MaerkenIsabel Leroux-RoelsB DelaereL MellyB RondeletC DransartAS DincqI MichauxP BogaertsY Glupczynski

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

2018

Improving timelines in reporting results from positive blood cultures : simulation of impact of rapid identification on therapy on a real-life cohort

Lien CattoirLiselotte CoorevitsIsabel Leroux-RoelsGeert ClaeysBruno VerhasseltJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

2017

Surveillance of endoscopes : comparison of different sampling techniques

Lien CattoirThomas VanzieleghemLisa FlorinTania HelleputteMartine De VosBruno VerhasseltJerina BoelensIsabel Leroux-Roels

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

2016

Antibody persistence and booster responses to split-virion H5N1 avian influenza vaccine in young and elderly adults

Rajeka LazarusSarah KellyMatthew D SnapeCorinne VandermeulenMerryn VoyseyKarel HoppenbrouwersAnnick HensPierre Van DammeStephanie PepinIsabel Leroux-RoelsGeert Leroux-RoelsAndrew J Pollard

A1 Journal Article in PLOS ONE

LISBETH VANDENABEELEGeertrui CoppensIsabel Leroux-RoelsPieter Hindryckx

Editorial material

2015

Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: randomised, controlled trials

Isabel Leroux-RoelsJeanne-Marie DevasterGeert Leroux-RoelsVincent VerlantIsabelle HenckaertsPhilippe MorisPhilippe HermandPascale Van BelleJan T PoolmanPierre VandepapeliéreYves Horsmans

A1 Journal Article in VACCINE

Influenza vaccines: where do we stand? Where do we go? A bumpy but steady road upwards

Guus RimmelzwaanIsabel Leroux-RoelsS GilbertA Thomson

Editorial material

2014

Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines : randomized, double-blind study in malaria-naïve adults

Geert Leroux-RoelsIsabel Leroux-RoelsFrédéric ClementOpokua Ofori-AnyinamMarc LievensErik JongertPhilippe MorisW Ripley BallouJoe Cohen

A1 Journal Article in HUMAN VACCINES & IMMUNOTHERAPEUTICS

Implementation of a multidisciplinary infectious diseases team in a tertiary hospital within an Antimicrobial Stewardship Program

Franky BuyleMATTHIAS WALLAERTNATHALIE BECKJerina BoelensSteven CallensGeert ClaeysSABINE DERYCKEREEVELIEN HAEGEMANIsabel Leroux-RoelsERICA SERMIJNEVA STEELHugo RobaysLinos VandekerckhoveKaren VermisDirk Vogelaers

A1 Journal Article in ACTA CLINICA BELGICA

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveJerina BoelensGeert ClaeysIsabel Leroux-RoelsEric HostePieter DepuydtJohan DecruyenaereAlain Verstraete

A1 Journal Article in INTENSIVE CARE MEDICINE

Validity analysis of a unique infection surveillance system in the intensive care unit by analysis of a data warehouse built through a workflow-integrated software application

Liesbet De BusGUNTER DIETBram GadeyneIsabel Leroux-RoelsGeert ClaeysKristof SteurbautDominique BenoitFilip De TurckJohan DecruyenaerePieter Depuydt

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

2013

Characeteristics and outcome of neonates with a healthcare-associated bloodstream infection in a NICU over a 10-year period (2002-2011)

Evelien VerstraeteGeert ClaeysIsabel Leroux-RoelsDirk VogelaersPiet VanhaesebrouckStijn Blot

Clinical evaluation to confirm the manufacturing consistency of three lots of an adjuvanted glycoprotein D genital herpes vaccine in healthy seronegative pre-teen and adolescent girls: a phase III multi-center double-blind randomized trial

Geert Leroux-RoelsSimon DobsonDavid I BernsteinSandra FowlerBarbara RomanowskiIsabel Leroux-RoelsBrigitte CheuvartThomas HeinemanGary Dubin

A2 Journal Article in TRIALS IN VACCINOLOGY

Edwardsiella tarda sepsis in a live-stranded sperm whale (Physeter macrocephalus)

Piet CoolsJan HaeltersGuido Lopes dos Santos SantiagoGeert ClaeysJerina BoelensIsabel Leroux-RoelsMario VaneechouttePieter Deschaght

A1 Journal Article in VETERINARY MICROBIOLOGY

Improved CD4⁺ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: a randomized trial

Isabel Leroux-RoelsSheron ForgusFIEN DE BOEVERFrédéric ClementMarie-Ange DemoitiéPascal MettensPhilippe MorisEdouard LedentGeert Leroux-RoelsOpokua Ofori-Anyinam

A1 Journal Article in VACCINE

Safety and immunogenicity of a glycoprotein D genital herpes vaccine in healthy girls 10-17 years of age: results from a randomised, controlled, double-blind trial

The HSV-040 Study groupJH RichardusRR Abu-ElyazeedT HeinemanG DubinM FourneauIsabel Leroux-RoelsGeert Leroux-RoelsL OstergaardJ Diez-DomingoA PoderP Van DammeB RomanowskiM BlatterSA Silfverdal

A1 Journal Article in VACCINE

2012

A phase 1/2 clinical trial evaluating safety and immunogenicity of a varicella zoster glycoprotein E subunit vaccine candidate in young and older adults

Isabel Leroux-RoelsGeert Leroux-RoelsFrédéric ClementPierre VandepapelièreVentzislav VassilevEdouard LedentThomas C Heineman

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

2011

H5N1 influenza vaccine formulated with AS03A induces strong cross-reactive and polyfunctional CD4 T-cell responses

Philippe MorisRobbert van der MostIsabel Leroux-RoelsFrédéric ClementMamadou DraméEmmanuel HanonGeert Leroux-RoelsMarcelle Van Mechelen

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Head-to-head comparison of pandemic influenza vaccines

Geert Leroux-RoelsIsabel Leroux-Roels

Editorial material

2010

Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02A candidate tuberculosis vaccine in purified protein derivative-negative adults

Isabel Leroux-RoelsGeert Leroux-RoelsOpokua Ofori-AnyinamPhilippe MorisEls De KockFrédéric ClementMarie-Claude DuboisMarguerite KoutsoukosMarie-Ange DemoitieJoe CohenW Ripley Ballou

A1 Journal Article in CLINICAL AND VACCINE IMMUNOLOGY

Inactivated split-virion seasonal influenza vaccine (Fluarix®) : a review of its use in the prevention of seasonal influenza in adults and the elderly

Monique P CurranIsabel Leroux-Roels

A1 Journal Article in DRUGS

Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study

Isabel Leroux-RoelsFlorian RomanSheron ForgusCathy MaesFIEN DE BOEVERMamadou DramePaul GillardRobbert van der MostMarcelle Van MechelenEmmanuel HanonGeert Leroux-Roels

A1 Journal Article in VACCINE

Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three Adjuvant Systems

Isabel Leroux-RoelsMarguerite KoutsoukosFrédéric ClementSophia SteyaertMichel JanssensPatricia BourguignonKristen CohenMarcus AltfeldPierre VandepapelièreLouise PedneaultLisa McNallyGeert Leroux-RoelsGerald Voss

A1 Journal Article in VACCINE

2009

Current status and progress of prepandemic and pandemic influenza vaccine development

Isabel Leroux-RoelsGeert Leroux-Roels

A1 Journal Article in EXPERT REVIEW OF VACCINES

Humoral and cellular immune responses to split-virion H5N1 influenza vaccine in young and elderly adults

Isabel Leroux-RoelsMarie Van der WielenFroukje KafejaCorinne VandermeulenRajeka LazarusMatthew D SnapeTessa JohnChristophe CarreNolwenn NougaredeStephanie PepinGeert Leroux-RoelsKarel HoppenbrouwersAndrew J PollardPierre Van Damme

A1 Journal Article in VACCINE

2008

An adjuvanted, low-dose, pandemic influenza a (H5N1) vaccine candidate is safe, immunogenic, and induces cross-reactive immune responses in healthy adults

Karin LevieIsabel Leroux-RoelsKarel HoppenbrouwersAnne-Diane KervynCorinne VandermeulenSheron ForgusGeert Leroux-RoelsSylvie PichonInca Kusters

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Broad clade 2 cross-reactive immunity induced by an adjuvanted clade 1 rH5N1 pandemic influenza vaccine

Isabel Leroux-RoelsRoger BernhardPascal GérardMamadou DraméEmmanuel HanonGeert Leroux-Roels

A1 Journal Article in PLOS ONE

Seasonal influenza vaccine delivered by intradermal microinjection: A randomised controlled safety and immunogenicity trial in adults

Isabel Leroux-RoelsEva VetsRalf FreeseMichael SeiberlingFrancoise WeberCamille SalamandGeert Leroux-Roels

A1 Journal Article in VACCINE

2007

Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial

Isabel Leroux-RoelsAstrid BorkowskiTHOMAS VANWOLLEGHEMMamadou DrameFrédéric ClementEliane HonsJeanne-Marie DevasterGeert Leroux-Roels

A1 Journal Article in LANCET