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Researcher
Ine Lentacker
Profile
Projects
Publications
Activities
Awards & Distinctions
77
Results
2022
Evaluation of liposome-loaded microbubbles as a theranostic tool in a murine collagen-induced arthritis model
Joke Deprez
Silke Roovers
Guillaume Lajoinie
Heleen Dewitte
Tine Decruy
Julie Coudenys
Benedicte Descamps
Christian Vanhove
Michel Versluis
Dirk Elewaut
et al.
A2
Journal Article
in
SCIENTIA PHARMACEUTICA
2022
Fluorine MR imaging probes dynamic migratory profiles of perfluorocarbon-loaded dendritic cells after streptozotocin-induced inflammation
Shweta Saini
An-Sofie Vanherwegen
Sayuan Liang
Rein Verbeke
Hannelie Korf
Ine Lentacker
Stefaan De Smedt
Conny Gysemans
Uwe Himmelreich
A1
Journal Article
in
MOLECULAR IMAGING AND BIOLOGY
2022
Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes
Rupert Mayer
Rein Verbeke
Caroline Asselman
Ilke Aernout
Adillah Gul
Denzel Eggermont
Katie Boucher
Fabien Henri Thery
Teresa Maia
Hans Demol
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2022
Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer
Ragna Haegebaert
Maxime Kempers
Wim Ceelen
Ine Lentacker
Katrien Remaut
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2022
2021
Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells
Aranit Harizaj
Benedicte Descamps
Christophe Mangodt
Stephan Stremersch
Arianna Stoppa
Lieve Balcaen
Toon Brans
Hilde De Rooster
Nausikaa Devriendt
Juan Fraire
et al.
A1
Journal Article
in
BIOMATERIALS SCIENCE
2021
Exploring novel drug delivery strategies in rheumatoid arthritis : nanomedicines and ultrasound triggered drug delivery
Joke Deprez
Stefaan De Smedt
Peggy Jacques
Ine Lentacker
Dissertation
2021
Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger
Aranit Harizaj
Filip Van Hauwermeiren
Stephan Stremersch
Riet De Rycke
Herlinde De Keersmaecker
Toon Brans
Juan Fraire
Karolien Grauwen
Stefaan De Smedt
Ine Lentacker
et al.
A1
Journal Article
in
NANOSCALE
2021
Opening doors with ultrasound and microbubbles : beating biological barriers to promote drug delivery
Joke Deprez
G. Lajoinie
Yanou Engelen
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2021
Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells
Aranit Harizaj
Mike Wels
Laurens Raes
Stephan Stremersch
Glenn Goetgeluk
Toon Brans
Bart Vandekerckhove
Félix Sauvage
Stefaan De Smedt
Ine Lentacker
et al.
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2021
Physical transfection technologies for macrophages and dendritic cells in immunotherapy
Aranit Harizaj
Stefaan De Smedt
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
EXPERT OPINION ON DRUG DELIVERY
2021
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across
An-Katrien Minnaert
Helena Vanluchene
Rein Verbeke
Ine Lentacker
Stefaan De Smedt
Koen Raemdonck
Niek Sanders
Katrien Remaut
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2021
The dawn of mRNA vaccines : the COVID-19 case
Rein Verbeke
Ine Lentacker
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2021
mRNA in cancer immunotherapy : beyond a source of antigen
Lien Van Hoecke
Rein Verbeke
Heleen Dewitte
Ine Lentacker
Karim Vermaelen
Karine Breckpot
Sandra Van Lint
A1
Journal Article
in
MOLECULAR CANCER
2021
2020
Light-responsive nanoparticles : from bio-imaging to intracellular delivery
Aranit Harizaj
Kevin Braeckmans
Ine Lentacker
Dirk Poelman
Dissertation
2020
Ultrasound-responsive cavitation nuclei for therapy and drug delivery
Klazina Kooiman
Silke Roovers
Simone A. G. Langeveld
Robert T. Kleven
Heleen Dewitte
Meaghan A. O'Reilly
Jean-Michel Escoffre
Ayache Bouakaz
Martin D. Verweij
Kullervo Hynynen
et al.
A1
Journal Article
in
ULTRASOUND IN MEDICINE AND BIOLOGY
2020
mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice
Lien Van Hoecke
Rein Verbeke
Dorien De Vlieger
Heleen Dewitte
Kenny Roose
Sharon Van Nevel
Olga Krysko
Claus Bachert
Bert Schepens
Ine Lentacker
et al.
A1
Journal Article
in
MOLECULAR THERAPY-NUCLEIC ACIDS
2020
2019
Biocompatible lipid‐coated persistent luminescent nanoparticles for in vivo imaging of dendritic cell migration
Aranit Harizaj
Olivier De Clercq
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Dirk Poelman
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
2019
Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells
Rein Verbeke
Ine Lentacker
Karine Breckpot
Jonas Janssens
Serge Van Calenbergh
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
ACS NANO
2019
Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model
Shweta Saini
Hannelie Korf
Sayuan Liang
Rein Verbeke
Bella Manshian
Koen Raemdonck
Ine Lentacker
Conny Gysemans
Stefaan De Smedt
Uwe Himmelreich
A1
Journal Article
in
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
2019
Enhancing nucleic acid delivery with ultrasound and microbubbles
Heleen Dewitte
Silke Roovers
Stefaan De Smedt
Ine Lentacker
Bookchapter
in
Nanotechnology for nucleic acid delivery : methods and protocols
2019
Longitudinal in vivo assessment of host-microbe interactions in a murine model of pulmonary aspergillosis
Shweta Saini
Jennifer Poelmans
Hannelie Korf
James L. Dooley
Sayuan Liang
Bella B. Manshian
Rein Verbeke
Stefaan J. Soenen
Greetje Vande Velde
Ine Lentacker
et al.
A1
Journal Article
in
ISCIENCE
2019
Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound
Silke Roovers
Joke Deprez
D Priwitaningrum
G Lajoinie
N Rivron
Heidi Declercq
Olivier De Wever
E Stride
S Le Gac
M Versluis
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2019
Sonoprinting of nanomedicines : from mechanistic insights to preclinical translation
Silke Roovers
Stefaan De Smedt
Ine Lentacker
Dissertation
2019
Sonoprinting of nanoparticle-loaded microbubbles : unraveling the multi-timescale mechanism
Silke Roovers
Guillaume Lajoinie
Ine De Cock
Toon Brans
Heleen Dewitte
Kevin Braeckmans
Michel Versuis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
BIOMATERIALS
2019
The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation
Silke Roovers
Tim Segers
Guillaume Lajoinie
Joke Deprez
Michel Versluis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
LANGMUIR
2019
Three decades of messenger RNA vaccine development
Rein Verbeke
Ine Lentacker
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
NANO TODAY
2019
Trap levels in persistent phosphors for bio-imaging
Dirk Poelman
Olivier De Clercq
Jiaren Du
Aranit Harizaj
Ine Lentacker
Kevin Braeckmans
C3
Conference
2019
2018
Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles
Guillaume Lajoinie
Ying Luan
Erik Gelderblom
Benjamin Dollet
Frits Mastik
Heleen Dewitte
Ine Lentacker
Nico de Jong
Michel Versluis
A1
Journal Article
in
COMMUNICATIONS PHYSICS
2018
Optimized messenger RNA immunolipoplexes for cancer immunotherapy : balancing immunogenicity and adjuvancy
Rein Verbeke
Ine Lentacker
Karine Breckpot
Serge Van Calenbergh
Stefaan De Smedt
Heleen Dewitte
C3
Conference
2018
Tri-modal in vivo imaging of pancreatic islets transplanted subcutaneously in mice
Sayuan Liang
Karim Louchami
Bryan Holvoet
Rein Verbeke
Christophe M Deroose
Bella Manshian
Stefaan J Soenen
Ine Lentacker
Uwe Himmelreich
A1
Journal Article
in
MOLECULAR IMAGING AND BIOLOGY
2018
2017
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy : restoring the immunogenicity of immunosilent mRNA
Rein Verbeke
Ine Lentacker
Laura Wayteck
Karine Breckpot
Mieke Van Bockstal
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2017
Co-delivery of nucleoside-modified mRNA and immunomodulators for cancer immunotherapy: restoring the immunogenicity of immunosilent mRNA
Rein Verbeke
Ine Lentacker
Laura Wayteck
Karine Breckpot
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Heleen Dewitte
C3
Conference
2017
Dynamic fluorescence microscopy of cellular uptake of intercalating model drugs by ultrasound-activated microbubbles
BHA Lammertink
R Deckers
M Derieppe
Ine De Cock
Ine Lentacker
G Storm
CTW Moonen
C Bos
A1
Journal Article
in
MOLECULAR IMAGING AND BIOLOGY
2017
mRNA-based nanoparticles for therapeutic cancer vaccination
Rein Verbeke
Laura Wayteck
Karine Breckpot
Christian Vanhove
Benedicte Descamps
Stefaan De Smedt
Heleen Dewitte
Ine Lentacker
C3
Conference
2017
2016
In vitro methods to study bubble-cell interactions : fundamentals and therapeutic applications
Guillaume Lajoinie
Ine De Cock
Constantin C Coussios
Ine Lentacker
Séverine Le Gac
Eleanor Stride
Michel Versluis
A1
Journal Article
in
BIOMICROFLUIDICS
2016
Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon
Katrijn Broos
Kevin Vanderjeught
Janik Puttemans
Cleo Goyvaerts
Carlo Heirman
Heleen Dewitte
Rein Verbeke
Ine Lentacker
Kris Thielemans
Karine Breckpot
A2
Journal Article
in
MOLECULAR THERAPY-NUCLEIC ACIDS
2016
Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles
Ine De Cock
Guillaume Lajoinie
Michel Versluis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
BIOMATERIALS
2016
Unraveling microbubble-cell interactions and drug delivery mechanisms in ultrasound-guided therapy
Ine De Cock
Stefaan De Smedt
Ine Lentacker
Dissertation
2016
2015
Design and evaluation of immunotherapeutic imaging for cancer vaccination
Heleen Dewitte
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
Dissertation
2015
Evaluation of mRNA lipoplexes for single-step antigen loading and maturation of dendritic cells in cancer immunotherapy
Rein Verbeke
Heleen Dewitte
Ine Lentacker
Stefaan De Smedt
C3
Conference
2015
Immunogenic mRNA nanoparticles for dendritic cell-based cancer vaccination
Rein Verbeke
Heleen Dewitte
Ine Lentacker
Stefaan De Smedt
C3
Conference
2015
Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells
Ranhua Xiong
Koen Raemdonck
Karen Peynshaert
Ine Lentacker
Ine De Cock
Jo Demeester
Stefaan De Smedt
Andre Skirtach
Kevin Braeckmans
P1
Conference
2015
Microbubbles as magic bullets in cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Hendrik Haers
Emmelie Stock
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2015
The ReNAissanCe of mRNA-based cancer therapy
Sandra Van Lint
Dries Renmans
Katrijn Broos
Heleen Dewitte
Ine Lentacker
Carlo Heirman
Karine Breckpot
Kris Thielemans
A1
Journal Article
in
EXPERT REVIEW OF VACCINES
2015
Theranostic mRNA-loaded microbubbles in the lymphatics of dogs: implications for drug delivery
Heleen Dewitte
Katrien Vanderperren
Hendrik Haers
Emmelie Stock
Luc Duchateau
Myriam Hesta
Jimmy Saunders
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
THERANOSTICS
2015
Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis
Ine De Cock
Elisa Zagato
Kevin Braeckmans
Ying Luan
Nico de Jong
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
2014
Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro
Heleen Dewitte
Rein Verbeke
Karine Breckpot
Roosmarijn Vandenbroucke
Claude Libert
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells
Ranhua Xiong
Koen Raemdonck
Karen Peynshaert
Ine Lentacker
Ine De Cock
Jo Demeester
Stefaan De Smedt
Andre Skirtach
Kevin Braeckmans
A1
Journal Article
in
ACS NANO
2014
Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment
Heleen Dewitte
Rein Verbeke
Karine Breckpot
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
NANO TODAY
2014
The bubble breakthrough in cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Carlo Heirman
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Understanding ultrasound induced sonoporation: definitions and underlying mechanisms
Ine Lentacker
Ine De Cock
R Deckers
Stefaan De Smedt
CTW Moonen
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2014
2013
Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and 19F-MRI tracking of dendritic cells
Heleen Dewitte
Bart Geers
Sayuan Liang
Uwe Himmelreich
Jo Demeester
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2013
Enhancing nucleic acid delivery with ultrasound and microbubbles
Steven Cool
Bart Geers
Ine Lentacker
Stefaan De Smedt
Niek Sanders
Bookchapter
in
Nanotechnology for nucleic acid delivery : methods and protocols
2013
Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB opening
Angelika Alonso
Eileen Reinz
Barbara Leuchs
Juergen Kleinschmidt
Marc Fatar
Bart Geers
Ine Lentacker
Michael G. Hennerici
Stefaan De Smedt
Stephen Meairs
A1
Journal Article
in
MOLECULAR THERAPY-NUCLEIC ACIDS
2013
Injectable drug-loaded microbubbles : a magic bullet for image-guided cancer therapy?
Bart Geers
Stefaan De Smedt
Jo Demeester
Ine Lentacker
Dissertation
2013
Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery
Bart Geers
Olivier De Wever
Jo Demeester
Marc Bracke
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
SMALL
2013
2012
Crucial factors and emerging concepts in ultrasound-triggered drug delivery
Bart Geers
Heleen Dewitte
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
The mechanisms behind sonoporation through the eyes of an AAV-vector
Bart Geers
Ine Lentacker
Angelika Alonso
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A2
Journal Article
in
PUBLICATIONS QUARTERLY / AMERICAN CHEMICAL SOCIETY
2012
2011
Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles
Bart Geers
Ine Lentacker
Angelika Alonso
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2011
Self-assembled liposome-loaded microbubbles: the missing link for safe and efficient ultrasound triggered drug-delivery
Bart Geers
Ine Lentacker
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2011
mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells
Marie-Luce De Temmerman
Heleen Dewitte
Roosmarijn Vandenbroucke
Bart Lucas
Claude Libert
Jo Demeester
Stefaan De Smedt
Ine Lentacker
Joanna Rejman
A1
Journal Article
in
BIOMATERIALS
2011
2010
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved
Ine Lentacker
Bart Geers
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
MOLECULAR THERAPY
2010
2009
Design and evaluation of drug loaded microbubbles for ultrasound guided cancer therapy
Ine Lentacker
Niek Sanders
Stefaan De Smedt
Jo Demeester
Dissertation
2009
Drug loaded microbubble design for ultrasound triggered delivery
Ine Lentacker
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
SOFT MATTER
2009
Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes
Ine Lentacker
Nan Wang
Roosmarijn Vandenbroucke
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2009
2008
Can ultrasound solve the transport barrier of the neural retina?
Liesbeth Peeters
Ine Lentacker
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Niek Sanders
Stefaan De Smedt
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2008
Circumventing the endocytotic uptake of highly PEGylated lipoplexes by using lipoplex loaded microbubbles and ultrasound can drastically increase their transfection efficiency
Ine Lentacker
Stefaan De Smedt
Niek Sanders
C3
Conference
2008
Loading of PEGylated siRNA lipoplexes on microbubbles restores their siRNA delivery capacity in the presence of ultrasound
Roosmarijn Vandenbroucke
Ine Lentacker
Jo Demeester
Stefaan De Smedt
Niek Sanders
C1
Conference
2008
New strategies for nucleic acid delivery to conquer cellular and nuclear membranes
Ine Lentacker
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
Journal of Controlled Release
2008
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles
Roosmarijn Vandenbroucke
Ine Lentacker
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2008
2007
Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound
Ine Lentacker
Stefaan De Smedt
Jo Demeester
Veerle Van Marck
Marc Bracke
Niek Sanders
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2007
Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer
Niek Sanders
Liesbeth Peeters
Ine Lentacker
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2007
2006
Microbubbles which bind and protect DNA against nucleases
Ine Lentacker
Stefaan De Smedt
Jo Demeester
Niek Sanders
C3
Conference
2006
Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA
Ine Lentacker
Bruno De Geest
Roosmarijn Vandenbroucke
Liesbeth Peeters
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
LANGMUIR
2006