Research Explorer

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Researcher

Gert Van Isterdael

Publications & Research Data

Awards & Distinctions

57 Results

2026

Cyt-Geist : current and future challenges in cytometry : reports of the CYTO 2025 Conference Workshops

Paul K. WallaceEvan R. JellisonSherry ThorntonKathleen KluepfelJessica BackThomas C. BeadnellAttila BebesJochen BehrendsAnna C. BelkinaMichele Black et al.

Editorial material

2025

Continuous FACS sorting of double emulsion picoreactors with a 3D-printed vertical mixer

Zijian YangSamuel ThompsonYanrong ZhangIene RuttenJulie Van DuyseGert Van IsterdaelLisa NicholsJeroen LammertynHyongsok T. SohPolly Fordyce

A1 Journal Article in ANALYTICAL CHEMISTRY

IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells

Bin YangOphélie PiedfortGuillem Sanchez-SanchezArnaud LavergneMeijiao GongGarrie PengAriel MadrigalGeorgios PetrellisBrunette KatsandegwazaLucia Rodriguez Rodriguez et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

2024

Automated antibody dispensing to improve high-parameter flow cytometry throughput and analysis

Victor BosteelsJulie Van DuyseElien RuyssinckKatrien Van Der BorghtLong NguyenJannes GavelSophie JanssensGert Van Isterdael

A1 Journal Article in CYTOMETRY PART A

Best practices for user consultation in flow cytometry shared resource laboratories

Kewal AsosinghAlice BayiyanaMichele C. BlackUttara ChakrabortyMichael J. ClementeAmy C. GrahamMichael D. GregoryKaren G. HoggGert Van IsterdaelChunchun Liu et al.

A1 Journal Article in CYTOMETRY PART A

The unfolded protein sensor IRE1a is essential for homeostatic dendritic cell maturation

Sophie JanssensVictor BosteelsSandra MaréchalEva ClootsLaurien Van HeddegemSimon TavernierSofie RennenClint De NolfSeraja AmstelveenJonathan Maelfait et al.

2023

A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis

Trang Hieu NguyenLouis ThiersAlex Van MoerkerckeYuechen BaiPatricia Fernandez CalvoMax MinneThomas DepuydtMaite Colinas MartinezKevin VerstaenGert Van Isterdael et al.

A1 Journal Article in NATURE PLANTS

Guidelines for establishing a cytometry laboratory

Anna C. BelkinaCaroline E. RoeVera A. TangJessica B. BackClaudia BispoAlexis ConwayUttara ChakrabortyKathleen T. DanielsGelo de la CruzLaura Ferrer-Font et al.

A1 Journal Article in CYTOMETRY PART A

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim Deswarte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis

Dieter TulkensMarthe BoelensThomas NaertMarjolein CarronSuzan DemuynckSylviane DewaeleGert Van IsterdaelDavid CreytensTim PietersSteven Goossens et al.

A1 Journal Article in LEUKEMIA

Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space

E AdriaenssensB AsselberghP Rivera-MejíasS BervoetsL VendredyV De WinterK SpaasRiet De RyckeGert Van IsterdaelFrancis Impens et al.

A1 Journal Article in NATURE CELL BIOLOGY

Spatial and temporal regulation of parent-of-origin allelic expression in the endosperm

Yuri S van EkelenburgKarina S HornslienTom Van HautegemMatyas FendrychGert Van IsterdaelKatrine N BjerkanJason R. MillerMoritz NowackPaul E Grini

A1 Journal Article in PLANT PHYSIOLOGY

Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform

Christophe GaillochetAlexandra Pena FernandezVera GoossensKatelijn D’HalluinAndrzej DrozdzeckiMyriam ShafieJulie Van DuyseGert Van IsterdaelCamila GonzalezMattias Vermeersch et al.

A1 Journal Article in GENOME BIOLOGY

Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

Joke DeprezRein VerbekeSofie MeulewaeterIlke AernoutHeleen DewitteTine DecruyJulie CoudenysJulie Van DuyseGert Van IsterdaelDan Peer et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

2022

How tech-savvy employees make the difference in core facilities : recognizing core facility expertise with dedicated career tracks

Saskia LippensDominique AudenaertAlexander BotzkiStefaan DerveauxBart GhesquièreGeert GoeminneReza HassanzadehJurgen HaustraeteFrancis ImpensJochen Lamote et al.

Editorial material

PeacoQC : peak-based selection of high quality cytometry data

Annelies EmmaneelKatrien QuintelierDorine SichienPaulina RybakowskaConcepcion MaranonMarta E. Alarcon-RiquelmeGert Van IsterdaelSofie Van GassenYvan Saeys

A1 Journal Article in CYTOMETRY PART A

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho NunesLisa DepestelLiselot MusKaylee M. KellerLouis DelhayeAmber LouwagieMuhammad RishfiAlex WhaleNeesha KaraSimon R. Andrews et al.

A1 Journal Article in SCIENCE ADVANCES

Single-cell transcriptomics sheds light on the identity and metabolism of developing leaf cells

Rubén Tenorio BerrioKevin VerstaenNiels VandammeJulie PevernagieIgnacio AchónJulie Van DuyseGert Van IsterdaelYvan SaeysLieven De VeylderDirk Inzé et al.

A1 Journal Article in PLANT PHYSIOLOGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Non-cell autonomous and spatiotemporal signaling from a tissue organizer orchestrates root vascular development

Baojun YangMax MinneFederica BrunoniLenka PlačkováIvan PetříkYanbiao SunJonah NolfWouter SmetKevin VerstaenJos Wendrich et al.

A1 Journal Article in NATURE PLANTS

2020

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis

Thomas NaertDionysia DimitrakopoulouDieter TulkensSuzan DemuynckMarjolein CarronRivka NoelandersLiza EeckhoutGert Van IsterdaelDieter DeforceChristian Vanhove et al.

A1 Journal Article in ONCOGENE

Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions

Jos WendrichBaojun YangNiels VandammeKevin VerstaenWouter SmetCelien Van de VeldeMax MinneBrecht WybouwEliana MorHelena Arents et al.

A1 Journal Article in SCIENCE

2019

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon TavernierV AthanasopoulosPATRICK VERLOOG BehrensJens StaalDelfien BogaertLeslie NaesensMarieke De BruyneSofie Van GassenEef Parthoens et al.

A1 Journal Article in NATURE COMMUNICATIONS

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van HoveLiesbet MartensIsabelle ScheyltjensKaren De VlaminckAna Rita Pombo AntunesSofie De PrijckNiels VandammeSebastiaan De SchepperGert Van IsterdaelCharlotte Scott et al.

A1 Journal Article in NATURE NEUROSCIENCE

CRISPR-TSKO : a technique for efficient mutagenesis in specific cell types, tissues, or organs in Arabidopsis

Ward DecaesteckerRafael Andrade BuonoMarie PfeifferNick VangheluweJoris JourquinMansour KarimiGert Van IsterdaelTom BeeckmanMoritz NowackThomas B. Jacobs

A1 Journal Article in PLANT CELL

Cyt-Geist : current and future challenges in cytometry : reports of the CYTO 2018 conference workshops

Kamila CzechowskaJoanne LanniganLili WangJudith ArcidiaconoThomas M AshhurstRuth M BarnardSteven BauerClaudia BispoDiana L BonillaRyan R Brinkman et al.

A1 Journal Article in CYTOMETRY PART A

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea CossarizzaHyun-Dong ChangAndreas RadbruchAndreas AcsDieter AdamSabine Adam-KlagesWilliam W AgaceNima AghaeepourMuebeccel AkdisMatthieu Allez et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Overexpression of Gilz protects mice against lethal septic peritonitis

Marlies BallegeerJolien VandewalleMelanie EggermontGert Van IsterdaelLien DejagerLiesbet De BusJohan DecruyenaereRoosmarijn VandenbrouckeClaude Libert

A1 Journal Article in SHOCK

2018

A spatiotemporal DNA endoploidy map of the Arabidopsis root reveals roles for the endocycle in root development and stress adaptation

Rahul BhosaleVéronique BoudolfFabiola Cuevas BustamanteRan LuThomas EekhoutZhubing HuGert Van IsterdaelGeorgina M LambertFan XuMoritz Nowack et al.

A1 Journal Article in PLANT CELL

Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells

Katrien Van Der BorghtCharlotte ScottLiesbet MartensDorine SichienGert Van IsterdaelVeronika NindlYvan SaeysLouis BoonBurkhard LudewigThierry Gillebert et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2017

Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain

Lana VandersarrenCedric BosteelsManon VanheerswynghelsJames J MoonAndrew J EastonGert Van IsterdaelSophie JanssensBart LambrechtMary van Helden

A1 Journal Article in SCIENTIFIC REPORTS

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon TavernierFabiola OsorioLana VandersarrenJessica VettersNele VanlangenakkerGert Van IsterdaelKarl VergoteRiet De RyckeEef ParthoensLianne van de Laar et al.

A1 Journal Article in NATURE CELL BIOLOGY

2016

A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress

Miguel AguiletaDiego Rojas RiveraVera GoossensYann EstornesGert Van IsterdaelPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively

Dorine SichienCharlotte ScottLiesbet MartensMatthias VanderkerkenSofie Van GassenMaud PlantingaThorsten JoerisSofie De PrijckLeen VanhoutteManon Vanheerswynghels et al.

A1 Journal Article in IMMUNITY

Mitochondria-associated membranes as hubs for neurodegeneration

Michiel KrolsGert Van IsterdaelBob AsselberghAnna KremerSaskia LippensVincent TimmermanSophie Janssens

A1 Journal Article in ACTA NEUROPATHOLOGICA

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Charlotte ScottBieke SoenLiesbet MartensNicolas SkrypekWouter SaelensJoachim TaminauGillian BlanckeGert Van IsterdaelDanny HuylebroeckJody Haigh et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages

Lianne van de LaarWouter SaelensSofie De PrijckLiesbet MartensCharlotte ScottGert Van IsterdaelEik HoffmannRudi BeyaertYvan SaeysBart Lambrecht et al.

A1 Journal Article in IMMUNITY

2015

A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development

Qian ChenYang LiuSteven MaereEunkyoung LeeGert Van IsterdaelZidian XieWei XuanJessica LucasValya VassilevaSaeko Kitakura et al.

A1 Journal Article in NATURE COMMUNICATIONS

Ethylene-mediated regulation of A2-type CYCLINs modulates hyponastic growth in Arabidopsis

Joanna K PolkoJop A van RooijSteffen VannesteRonald PierikAnkie MH AmmerlaanMarleen H Vergeer-van EijkFionn McLoughlinKerstin GühlGert Van IsterdaelLaurentius ACJ Voesenek et al.

A1 Journal Article in PLANT PHYSIOLOGY

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

Vanessa AndriesKarl VandepoeleKatrien StaesGeert BerxPieter BogaertGert Van IsterdaelDaisy GinnebergeEef ParthoensJonathan VandenbusscheKris Gevaert et al.

A1 Journal Article in BMC CANCER

Root cap-derived auxin pre-patterns the longitudinal axis of the Arabidopsis root

Wei XuanDominique AudenaertBoris ParizotBarbara MöllerMaria NjoBert De RybelGieljan De RopGert Van IsterdaelAri Pekka MähönenSteffen Vanneste et al.

A1 Journal Article in CURRENT BIOLOGY

2014

Arabidopsis NAC45/86 direct sieve element morphogenesis culminating in enucleation

Kaori Miyashima FurutaShri Ram YadavSatu LehesrantaIlya BelevichShunsuke MiyashimaJung-ok HeoAnne VaténOve LindgrenBert De RybelGert Van Isterdael et al.

A1 Journal Article in SCIENCE

Integration of growth and patterning during vascular tissue formation in Arabidopsis

Bert De RybelMilad AdibiAlice S BredaJos WendrichMargot E SmitOndřej NovákNobutoshi YamaguchiSaiko YoshidaGert Van IsterdaelJoakim Palovaara et al.

A1 Journal Article in SCIENCE

The cyclin-dependent kinase inhibitor KRP6 induces mitosis and impairs cytokinesis in giant cells induced by plant-parasitic nematodes in Arabidopsis

Paulo VieiraAnnelies De ClercqHilde StalsJelle Van LeeneEveline Van De SlijkeGert Van IsterdaelDominique EeckhoutGeert PersiauDaniël Van DammeAurine Verkest et al.

A1 Journal Article in PLANT CELL

The emerging role of reactive oxygen species signaling during lateral root development

Concepción ManzanoMerecedes Pallero-BaenaIlda CasimiroBert De RybelBeata Orman-LigezaGert Van IsterdaelTom BeeckmanXavier DrayePedro CaseroJuan C del Pozo

A1 Journal Article in PLANT PHYSIOLOGY

2011

Developmental regulation of CYCA2s contributes to tissue-specific proliferation in Arabidopsis

Steffen VannesteFrederik CoppensEunKyoung LeeTyler J. DonnerZidian XieGert Van IsterdaelStijn DhondtFreya De WinterBert De RybelMarnik Vuylsteke et al.

A1 Journal Article in EMBO JOURNAL

Isolation of transcription factor complexes from Arabidopsis cell suspension cultures by tandem affinity purification

Jelle Van LeeneDominique EeckhoutGeert PersiauEveline Van De SlijkeJan GeerinckGert Van IsterdaelErwin WittersGeert De Jaeger

Bookchapter in Plant transcription factors : methods and procotols

The Arabidopsis thaliana checkpoint kinase WEE1 protects against premature vascular differentiation during replication stress

Toon CoolsAnelia IantchevaAnnika K WeimerShannah BoensNaoki TakahashiSara MaesHilde Van Den DaeleGert Van IsterdaelArp SchnittgerLieven De Veylder

A1 Journal Article in PLANT CELL

2010

A novel Aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity

Bert De RybelValya VassilevaBoris ParizotMarlies DemeulenaereWim GrunewaldDominique AudenaertJelle Van CampenhoutPaul OvervoordeLeentje JansenSteffen Vanneste et al.

A1 Journal Article in CURRENT BIOLOGY

Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana

Jelle Van LeeneJens HollunderDominique EeckhoutGeert PersiauEveline Van De SlijkeHilde StalsGert Van IsterdaelAurine VerkestSandy NeirynckYelle Buffel et al.

A1 Journal Article in MOLECULAR SYSTEMS BIOLOGY

The roots of a new green revolution

Griet Den HerderGert Van IsterdaelTom BeeckmanIve De Smet

A1 Journal Article in TRENDS IN PLANT SCIENCE

2009

CDKB1;1 forms a functional complex with CYCA2;3 to suppress endocycle onset

Véronique BoudolfTim LammensJoanna BorucJelle Van LeeneHilde Van Den DaeleSara MaesGert Van IsterdaelEugenia RussinovaEva KondorosiErwin Witters et al.

A1 Journal Article in Plant Physiology

Manipulation of auxin transport in plant roots during Rhizobium symbiosis and nematode parasitism

Wim GrunewaldGiel Van NoordenGert Van IsterdaelTom BeeckmanGodelieve GheysenUlrike Mathesius

A1 Journal Article in PLANT CELL

Ontwikkeling van wortelstelsels, de verborgen helft van planten: hoe microscopie licht brengt in de duisternis

Tom BeeckmanDominique AudenaertGiel Van NoordenBoris ParizotBert De RybelWim GrunewaldLeentje JansenLorena Lopez GalvisMirande NaudtsCharlotte Vanquickenborne et al.

Bookchapter in Micro, macro, mega : collectie Ocsinberg, keerpunt in de geschiedenis van de microscopie

2008

Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root

Ive De SmetValya VassilevaBert De RybelMitchell P LevesqueWim GrunewaldDaniël Van DammeGiel Van NoordenMirande NaudtsGert Van IsterdaelRebecca De Clercq et al.

A1 Journal Article in SCIENCE

2007

A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana

Jelle Van LeeneHilde StalsDominique EeckhoutGeert PersiauEveline Van De SlijkeGert Van IsterdaelAnnelies De ClercqEric BonnetKris LaukensNoor Remmerie et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2005

Cell cycle progression in the pericycle is not sufficient for SOLITARY ROOT/IAA14-mediated lateral root initiation in Arabidopsis thaliana

Steffen VannesteBert De RybelGerrit BeemsterKarin LjungIve De SmetGert Van IsterdaelMirande NaudtsRyusuke IidaWilhelm GruissemMasao Tasaka et al.

A1 Journal Article in PLANT CELL