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Filomeen Haerynck
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Prijzen & Erkenningen
239
Resultaten
2025
Clinical manifestations, disease penetrance, and treatment in individuals with SOCS1 insufficiency : a registry-based and population-based study
Jerome Hadjadj
Anna Wolfers
Oleg Borisov
Derek Hazard
Ronan Leahy
Marie Jeanpierre
Alexandre Belot
Shahrzad Bakhtiar
Fabian Hauck
Pui Y Lee
et al.
A1
Artikel in een tijdschrift
in
LANCET RHEUMATOLOGY
2025
Expanding diagnostics in primary immunodeficiency : integrating innovations in clinical laboratory practice
Jana Neirinck
Carolien Bonroy
Filomeen Haerynck
Celine Everaert
Proefschrift
2025
Fibroblast-based radiosensitivity assays as a clinically valuable tool for (severe) combined immunodeficiency syndromes
Elien Beyls
Somara De Beul
Victoria Bordon
Alina Ferster
Filomeen Haerynck
Anne Vral
Ans Baeyens
A1
Artikel in een tijdschrift
in
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
2025
Functional validation of a novel STAT3 ‘variant of unknown significance’ identifies a new case of STAT3 GOF syndrome and reveals broad immune cell defects
Joseph Mackie
Daniel Suan
Peter McNaughton
Filomeen Haerynck
Michael O’Sullivan
Antoine Guerin
Cindy S Ma
Stuart G Tangye
A1
Artikel in een tijdschrift
in
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
2025
Gastrointestinal disease in common variable immunodeficiency disorder (CVID) : histological patterns, diagnostic clues and pitfalls for the pathologist and gastroenterologist
Lars Velthof
Jeroen Geldof
Marie Truyens
Jo Van Dorpe
Liesbeth Ferdinande
Ciel De Vriendt
Tessa Kerre
Filomeen Haerynck
Triana Lobatón Ortega
Anne Hoorens
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL MEDICINE
2025
Investigating chromosomal radiosensitivity in inborn errors of immunity : insights from DNA repair disorders and beyond
Elien Beyls
Evi Duthoo
Lynn Backers
Karlien Claes
[missing] RAPID Clinicians
Tessa Kerre
B. Lambrecht
Levi Hoste
B. Meertens
T. Van Genechten
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2025
Multidimensional 1-year outcomes after intensive care admission for multisystem inflammatory syndrome in children
Thomas C. Seijbel
Levi Hoste
Corinne M. P. Buysse
Karolijn Dulfer
Filomeen Haerynck
Matthijs de Hoog
Naomi Ketharanathan
A2
Artikel in een tijdschrift
in
CRITICAL CARE EXPLORATIONS
2025
Recommendations for transitioning young people with primary immunodeficiency disorders and autoinflammatory diseases to adult care
Muskan Israni
Eliska Alderson
Nizar Mahlaoui
Laura Obici
Linda Rossi-Semerano
Helen Lachmann
Mojca Zajc Avramovič
Aurelien Guffroy
Virgil Dalm
Rachel Rimmer
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2025
Replication stress, microcephalic primordial dwarfism, and compromised immunity in ATRIP deficient patients
Evi Duthoo
Elien Beyls
Lynn Backers
Thorkell Gudjónsson
Peiquan Huang
Leander Jonckheere
Sebastian Riemann
Bram Parton
Likun Du
Veronique Debacker
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2025
The EuroFlow PIDOT external quality assurance scheme : enhancing laboratory performance evaluation in immunophenotyping of rare lymphoid immunodeficiencies
Jana Neirinck
Malicorne Buysse
Naděžda Brdickova
Martín Perez-Andres
Ciel De Vriendt
Tessa Kerre
Filomeen Haerynck
Xavier Bossuyt
Jacques J.M. van Dongen
Alberto Orfao
et al.
A1
Artikel in een tijdschrift
in
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
2025
2024
A novel heterozygous variant in AICDA impairs Ig class switching and somatic hypermutation in human B cells and is associated with autosomal dominant HIGM2 syndrome
Erika Della Mina
Katherine J. L. Jackson
Alexander J. I. Crawford
Megan L. Faulks
Karrnan Pathmanandavel
Nicolino Acquarola
Michael O’Sullivan
Tessa Kerre
Leslie Naesens
Karlien Claes
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2024
Age-dependent signature of serum inflammatory cytokines IL-1Ra, IL-1β, IL-6, IL-18, TNF-α, CXCL9 and CXCL10 in healthy children
Maarten Buytaert
Rachida El Kaddouri
Levi Hoste
Bram Meertens
Simon Tavernier
Veronique Debacker
Karlien Claes
Jo Dehoorne
Filomeen Haerynck
C3
Conferentie
2024
Clinical efficacy of SARS‐CoV‐2 Omicron‐neutralizing antibodies in immunoglobulin preparations for the treatment of agammaglobulinemia in patients with primary antibody deficiency
Michael Karbiener
Gerhard Kindle
Isabelle Meyts
Mikko R. J. Seppänen
Fabio Candotti
Marta Kamieniak
Reinhard Ilk
Thomas R. Kreil
Markus G. Seidel
Filomeen Haerynck
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL VIROLOGY
2024
European Society for Immunodeficiencies guidelines for the management of patients with congenital athymia
Alexandra Y. Kreins
Fatima Dhalla
Aisling M. Flinn
Evey Howley
Olov Ekwall
Anna Villa
Frank J.T. Staal
Graham Anderson
Andrew R. Gennery
Georg A. Holländer
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2024
Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome
Melissa Pille
John M. Avila
So Hyun Park
Cuong Q. Le
Haipeng Xue
Filomeen Haerynck
Lavanya Saxena
Ciaran Lee
Elizabeth J. Shpall
Gang Bao
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
2024
Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C)
Dilys Santillo
Pierre Vantourout
Heather R. Jackson
Amedine Duret
Henry Hearn
Yoann Seeleuthner
Estelle Talouarn
Stephanie Hodeib
Harsita Patel
Sophya Yeoh
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2024
Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children
Adrian Gervais
Maki Taniguchi
Liisa Saare
Karita Särekannu
Tom Le Voyer
Quentin Philippot
Jérémie Rosain
Lucy Bizien
Takaki Asano
Marina Garcia-Prat
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2024
Insights into radiosensitivity and defective DNA repair in immunodeficiency syndromes
Elien Beyls
Filomeen Haerynck
Simon Tavernier
Proefschrift
2024
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
Astrid Marchal
Elizabeth T. Cirulli
Iva Neveux
Evangelos Bellos
Ryan S. Thwaites
Kelly M. Schiabor Barrett
Yu Zhang
Ivana Nemes-Bokun
Mariya Kalinova
Andrew Catchpole
et al.
A2
Artikel in een tijdschrift
in
HUMAN GENETICS AND GENOMICS ADVANCES
2024
Longevity of the humoral and cellular responses after SARS-CoV-2 booster vaccinations in immunocompromised patients
Matthijs Oyaert
Marie-Angélique De Scheerder
Sophie Van Herrewege
Guy Laureys
Sofie Van Assche
Melissa Cambron
Leslie Naesens
Levi Hoste
Karlien Claes
Filomeen Haerynck
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2024
Made in Belgium : exploring the immune horizon : systemic inflammatory diseases in the era of SARS-CoV-2 and beyond
Levi Hoste
Filomeen Haerynck
Jo Dehoorne
Simon Tavernier
A2
Artikel in een tijdschrift
in
BELGIAN JOURNAL OF PAEDIATRICS
2024
PTPN2 deficiency expands the monogenetic causes of dysregulated JAK/STAT signaling resulting in autoimmunity
Leslie Naesens
Bram Meertens
Lore Pottie
Marieke De Bruyne
Ciel De Vriendt
Tessa Kerre
Simon Tavernier
Filomeen Haerynck
C3
Conferentie
2024
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency
Yi-Hao Chan
Vanja Lundberg
Jérémie Le Pen
Jiayi Yuan
Danyel Lee
Francesca Pinci
Stefano Volpi
Koji Nakajima
Vincent Bondet
Sanna Åkesson
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2024
Serum proteomics reveals hemophagocytic lymphohistiocytosis-like phenotype in a subset of patients with multisystem inflammatory syndrome in children
Adam J. Tulling
Marloes G. Holierhoek
Anja M. Jansen-Hoogendijk
Levi Hoste
Filomeen Haerynck
Simon Tavernier
Rianne Oostenbrink
Corinne M.P. Buysse
Michiel A.G.E. Bannier
Jolita Bekhof
et al.
A1
Artikel in een tijdschrift
in
CLINICAL IMMUNOLOGY
2024
Successful treatment of ulcerative colitis with anakinra : a case report
Marie Truyens
Levi Hoste
Jeroen Geldof
Anne Hoorens
Filomeen Haerynck
Diana Huis in 't Veld
Triana Lobatón Ortega
A1
Artikel in een tijdschrift
in
ACTA GASTRO-ENTEROLOGICA BELGICA
2024
The hyperPed-COVID international registry : impact of age of onset, disease presentation and geographical distribution on the final outcome of MIS-C
Roberta Caorsi
Alessandro Consolaro
Camilla Speziani
Betul Sozeri
Kadir Ulu
Enrique Faugier-Fuentes
Hector Menchaca-Aguayo
Seza Ozen
Seher Sener
Shahana Akhter Rahman
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF AUTOIMMUNITY
2024
The riddle of recurrent fever : a clinical approach to pediatric autoinflammatory diseases
Bram Meertens
Levi Hoste
Simon Tavernier
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
FRONTIERS IN PEDIATRICS
2024
2023
A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19
Karel Van Damme
Levi Hoste
Jozefien Declercq
Elisabeth De Leeuw
Bastiaan Maes
Liesbet Martens
Roos Colman
Robin Browaeys
Cedric Bosteels
Stijn Verwaerde
et al.
Preprint
2023
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
Karel Van Damme
Levi Hoste
Jozefien Declercq
Elisabeth De Leeuw
Bastiaan Maes
Liesbet Martens
Roos Colman
Robin Browaeys
Cedric Bosteels
Stijn Verwaerde
et al.
A1
Artikel in een tijdschrift
in
SCIENCE TRANSLATIONAL MEDICINE
2023
Activated phosphoinositide 3-kinase δ syndrome : update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
Maria Elena Maccari
Martin Wolkewitz
Charlotte Schwab
Tiziana Lorenzini
Jennifer W. Leiding
Nathalie Aladjdi
Hassan Abolhassani
Wadih Abou-Chahla
Alessandro Aiuti
Saba Azarnoush
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2023
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Tom Le Voyer
Audrey V. Parent
Xian Liu
Axel Cederholm
Adrian Gervais
Jérémie Rosain
Tina Nguyen
Malena Perez Lorenzo
Elze Rackaityte
Darawan Rinchai
et al.
A1
Artikel in een tijdschrift
in
NATURE
2023
COVID-19 vaccination in patients with primary immunodeficiencies : an international survey on patient vaccine hesitancy and self-reported adverse events
Martine Pergent
Filomeen Haerynck
Levi Hoste
Ann Gardulf
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2023
Central nervous system manifestations of LRBA deficiency : case report of two siblings and literature review
T. C. Mangodt
K. Vanden Driessche
K. K. Norga
N. Moes
Marieke De Bruyne
Filomeen Haerynck
Laura Teresa Bordon Viera
A. C. Jansen
A. I. Jonckheere
A1
Artikel in een tijdschrift
in
BMC PEDIATRICS
2023
Clinical practice of hereditary angioedema in Belgium : opportunities for optimized care
DG Ebo
MM Van der Poorten
AL Van Gasse
R. Schrijvers
C. Hermans
M. Bartiaux
Filomeen Haerynck
Julie Willekens
Hilde Lapeere
M. Moutschen
et al.
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2023
Combined deficient response to polysaccharide-based and protein-based vaccines predicts a severe clinical phenotype
Maaike Cockx
Filomeen Haerynck
Levi Hoste
Rik Schrijvers
Jutte Van der Werff ten Bosch
Doreen Dillaerts
Debby Thomas
Heidi Schaballie
Giorgia Bucciol
Wiert Robberechts
et al.
A1
Artikel in een tijdschrift
in
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
2023
Comparison of SARS-CoV-2 seroconversion in children with chronic diseases with healthy children and adults during the first waves of the COVID-19 pandemic
Levi Hoste
Agnieszka Prytula-Ebels
Jo Dehoorne
Ruth De Bruyne
Stephanie Van Biervliet
Kathleen De Waele
Evelyn Maes
Victoria Bordon
Arnaud Vanlander
Karlien Claes
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN PEDIATRICS
2023
Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever
Selina K. Jorch
Annika McNally
Philipp Berger
Jonas Wolf
Kim Kaiser
Andrian Chetrusca Covash
Stefanie Robeck
Isabell Pastau
Olesja Fehler
Saskia-L. Jauch-Speer
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2023
Editorial : the role of transcription factors in inborn errors of immunity
Delfien Bogaert
Hye Sun Kuehn
Victoria Bordon
Filomeen Haerynck
Redactioneel materiaal
2023
Exploring the immune horizon : systemic inflammatory diseases in the era of SARS-CoV-2 and beyond
Levi Hoste
Filomeen Haerynck
Jo Dehoorne
Simon Tavernier
Proefschrift
2023
From gastrointestinal enigma to genetic clarity : unraveling the MYH11 SM2 connection
Steven Callens
Bart Dermaut
Filomeen Haerynck
Dimitri Hemelsoet
Leslie Naessens
Bruce Poppe
Sanne Steyaert
Wim Terryn
Arnaud Vanlander
PATRICK VERLOO
et al.
C3
Conferentie
2023
Hereditary angioedema (HAE) in Belgium : results from a national survey
MM Van der Poorten
R Schrijvers
C Hermans
M Bartiaux
Filomeen Haerynck
Hilde Lapeere
M Moutschen
O Michel
V Sabato
DG Ebo
et al.
A2
Artikel in een tijdschrift
in
FRONTIERS IN ALLERGY
2023
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Ana García-García
Rebeca Pérez de Diego
Darawan Rinchai
Jordi Solé-Violán
Àngela Deyà-Martínez
Blanca García-Solis
José M. Lorenzo-Salazar
Elisa Hernández-Brito
Anna-Lisa Lanz
Leen Moens
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2023
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children : a propensity-weighted cohort study
Samuel Channon-Wells
Ortensia Vito
Andrew J McArdle
Eleanor G Seaby
Priyen Shah
Ekaterina Pazukhina
Clare Wilson
Claire Broderick
Giselle D'Souza
Ilana Keren
et al.
A1
Artikel in een tijdschrift
in
LANCET RHEUMATOLOGY
2023
Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity
Stuart G. Tangye
Laurent Abel
Salah Al-Muhsen
Alessandro Aiuti
Saleh Al-Muhsen
Fahd Al-Mulla
Mark S. Anderson
Evangelos Andreakos
Antonio Novelli
Andrés A. Arias
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2023
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Danyel Lee
Jérémie Le Pen
Ahmad Yatim
Beihua Dong
Yann Aquino
Masato Ogishi
Rémi Pescarmona
Estelle Talouarn
Darawan Rinchai
Peng Zhang
et al.
A1
Artikel in een tijdschrift
in
SCIENCE
2023
Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children
Giorgia Bucciol
Isabelle Meyts
Laurent Abel
Salah Al-Muhsen
Alessandro Aiuti
Fahd Al-Mulla
Evangelos Andreakos
Novelli Antonio
Andrés A. Arias
Sophie Trouillet-Assant
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2023
Innate immune sensors balance infection surveillance and autoinflammation
Leslie Naesens
Filomeen Haerynck
Tessa Kerre
Simon Tavernier
Proefschrift
2023
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Daniela Matuozzo
Estelle Talouarn
Astrid Marchal
Peng Zhang
Jeremy Manry
Yoann Seeleuthner
Yu Zhang
Alexandre Bolze
Matthieu Chaldebas
Baptiste Milisavljevic
et al.
A1
Artikel in een tijdschrift
in
GENOME MEDICINE
2023
Spleen function is reduced in individuals with NR5A1 variants with or without a difference of sex development : a cross-sectional study
Martine Cools
Celien Grijp
Jana Neirinck
Simon Tavernier
Petra Schelstraete
Julie Van De Velde
Lieve Morbée
Elfride De Baere
Carolien Bonroy
Yolande van Bever
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF ENDOCRINOLOGY
2023
The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation
Leslie Naesens
Filomeen Haerynck
Michaela U. Gack
A1
Artikel in een tijdschrift
in
TRENDS IN IMMUNOLOGY
2023
2022
A case of disseminated tuberculosis during a twin pregnancy following in vitro fertilization
L Kestens
Lander Van Acker
Anne Hoorens
Elke O. Kreps
Filomeen Haerynck
A Debrock
V Catry
Steven Weyers
Kristien Roelens
Eva Van Braeckel
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
2022
A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection
Evangelos Andreakos
Laurent Abel
Donald C. Vinh
Elżbieta Kaja
Beth A. Drolet
Qian Zhang
Cliona O’Farrelly
Giuseppe Novelli
Carlos Rodríguez-Gallego
Filomeen Haerynck
et al.
A1
Artikel in een tijdschrift
in
NATURE IMMUNOLOGY
2022
A novel S-micronucleus assay for radiosensitivity detection
Evi Duthoo
Filomeen Haerynck
Anne Vral
Ans Baeyens
C3
Conferentie
2022
Acute perimyocarditis in a case of multisystem inflammatory syndrome in adults
Jens Van Praet
Pascale De Paepe
Levi Hoste
Filomeen Haerynck
Redactioneel materiaal
2022
Autoantibodies against type I IFNs in patients with critical influenza pneumonia
Qian Zhang
Andres Pizzorno
Lisa Miorin
Paul Bastard
Adrian Gervais
Tom Le Voyer
Lucy Bizien
Jeremy Manry
Jeremie Rosain
Quentin Philippot
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2022
Autoimmune loss of entero-endocrine cells is a hallmark apeced manifestation that results in severe malabsorption but can recover with immune suppressants
Levi Hoste
Leslie Naesens
Sara Van Aken
Bruno Lapauw
Guy T'Sjoen
Charlotte Verroken
Nicolette Moes
Ruth De Bruyne
Tessa Kerre
Filomeen Haerynck
C3
Conferentie
2022
Decoding the human genetic and immunological basis of COVID-19 mRNA vaccine-induced myocarditis
Alexandre Bolze
Trine H. Mogensen
Shen-Ying Zhang
Laurent Abel
Evangelos Andreakos
Lisa M. Arkin
Alessandro Borghesi
Petter Brodin
David Hagin
Giuseppe Novelli
et al.
Redactioneel materiaal
2022
Delayed presentations of severe combined immunodeficiency during the SARS‑CoV‑2 pandemic
Levi Hoste
Giorgia Bucciol
Anniek Corveleyn
Stijn Cornelis
Victoria Bordon
Annik de Jaeger
Heidi Schaballie
Ellen Deolet
Jo Van Dorpe
Gregory Strubbe
et al.
C3
Conferentie
2022
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial
Elisabeth De Leeuw
Karel Van Damme
Jozefien Declercq
Cedric Bosteels
Bastiaan Maes
Simon Tavernier
Laurent Detalle
Trevor Smart
Sophie Glatt
Nincy Debeuf
et al.
A1
Artikel in een tijdschrift
in
RESPIRATORY RESEARCH
2022
Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients
Matthijs Oyaert
Marie-Angélique De Scheerder
Sophie Van Herrewege
Guy Laureys
Sofie Van Assche
Melissa Cambron
Leslie Naesens
Levi Hoste
Karlien Claes
Filomeen Haerynck
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2022
Familial hemophagocytic lymphohistiocytosis type 3 presenting as neonatal cholestasis and splenomegaly
Delfien Bogaert
Ruth De Bruyne
Arnaud Vanlander
Lara Garabedian
Yves Louis
Filomeen Haerynck
Victoria Bordon
Barbara De Moerloose
A1
Artikel in een tijdschrift
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2022
Fibroblast-based radiosensitivity assessment for primary immunodeficiency patients
Elien Beyls
Somara De Beul
Filomeen Haerynck
Victoria Bordon
Alina Ferster
Anne Vral
Ans Baeyens
C3
Conferentie
2022
GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141
Leslie Naesens
Santoshi Muppala
Dhiraj Acharya
Josephine Nemegeer
Delfien Bogaert
Jung-Hyun Lee
Katrien Staes
Veronique Debacker
Pieter De Bleser
Marieke De Bruyne
et al.
A1
Artikel in een tijdschrift
in
SCIENCE IMMUNOLOGY
2022
Human genetic and immunological determinants of critical COVID-19 pneumonia
Qian Zhang
Paul Bastard
Adem Karbuz
Adrian Gervais
Ahmad Abou Tayoun
Alessandro Aiuti
Alexandre Belot
Alexandre Bolze
Alexandre Gaudet
Anastasiia Bondarenko
et al.
A1
Artikel in een tijdschrift
in
NATURE
2022
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
Cedric Bosteels
Karel Van Damme
Elisabeth De Leeuw
Jozefien Declercq
Bastiaan Maes
Victor Bosteels
Levi Hoste
Leslie Naesens
Nincy Debeuf
Julie Deckers
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS MEDICINE
2022
Mental health outcomes among parents of children with a chronic disease during the COVID-19 pandemic : the role of parental burn-out
Aline Wauters
Tine Vervoort
Karlien Dhondt
Bart Soenens
Maarten Vansteenkiste
Sofie Morbée
Joachim Waterschoot
Filomeen Haerynck
Kristof Vandekerckhove
Helene Verhelst
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF PEDIATRIC PSYCHOLOGY
2022
Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement
Leslie Naesens
Josephine Nemegeer
Filip Roelens
Lore Vallaeys
Marije Meuwissen
Katrien Janssens
PATRICK VERLOO
Benson Ogunjimi
Dimitri Hemelsoet
Levi Hoste
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2022
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Qian Zhang
Daniela Matuozzo
Jérémie Le Pen
Danyel Lee
Leen Moens
Takaki Asano
Jonathan Bohlen
Zhiyong Liu
Marcela Moncada-Velez
Yasemin Kendir-Demirkol
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2022
SARS-CoV-2-related multisystem inflammatory syndrome in adult complicated by myocarditis and cardiogenic shock
Maarten De Smet
Jan Fierens
Lander Vanhulle
Yannick Vande Weygaerde
Thomas Malfait
Daniel Devos
Filomeen Haerynck
Sofie Gevaert
A1
Artikel in een tijdschrift
in
ESC HEART FAILURE
2022
Safety of COVID-19 vaccination in children with a history of MIS-C : an international survey
Levi Hoste
Antoni Soriano-Arandes
Emilie Pauline Buddingh
Elizabeth Whittaker
Alexandre Belot
Rolando Ulloa-Gutierrez
Peter Olbrich
Filomeen Haerynck
C3
Conferentie
2022
Severe acute respiratory syndrome coronavirus 2 vaccination in children with a history of multisystem inflammatory syndrome in children : an international survey
Levi Hoste
Antoni Soriano-Arandes
Emilie Pauline Buddingh
Elizabeth Whittaker
Alexandre Belot
Rolando Ulloa-Gutierrez
Peter Olbrich
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
JOURNAL OF PEDIATRICS
2022
Shortcutting the diagnostic odyssey : the multidisciplinary program for undiagnosed rare diseases in adults (UD-PrOZA)
Nika Schuermans
Dimitri Hemelsoet
Wim Terryn
Sanne Steyaert
Rudy Van Coster
Paul Coucke
Wouter Steyaert
Bert Callewaert
Elke Bogaert
Patrick Verloo
et al.
A1
Artikel in een tijdschrift
in
ORPHANET JOURNAL OF RARE DISEASES
2022
Studying severe long COVID to understand post-infectious disorders beyond COVID-19
Liam Townsend
Cliona O’Farrelly
Ivan Tancevski
Judith Löffler-Ragg
Trine H. Mogensen
Jean Laurent Casanova
Laurent Abel
Alessandro Aiuti
Saleh Al-Muhsen
Fahd Al-Mulla
et al.
A1
Artikel in een tijdschrift
in
NATURE MEDICINE
2022
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Levi Hoste
Lisa Roels
Leslie Naesens
Victor Bosteels
Stijn Vanhee
Sam Dupont
Cedric Bosteels
Robin Browaeys
Niels Vandamme
Kevin Verstaen
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2022
The Euroflow PID Orientation Tube in the diagnostic workup of primary immunodeficiency : daily practice performance in a tertiary university hospital
Jana Neirinck
Annelies Emmaneel
Malicorne Buysse
Jan Philippé
Sofie Van Gassen
Yvan Saeys
Xavier Bossuyt
Stefanie De Buyser
Mirjam van der Burg
Martin Perez-Andres
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2022
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Jérémy Manry
Paul Bastard
Adrian Gervais
Tom Le Voyer
Jérémie Rosain
Quentin Philippot
Eleftherios Michailidis
Hans-Heinrich Hoffmann
Shohei Eto
Marina Garcia-Prat
et al.
A1
Artikel in een tijdschrift
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2022
Whole blood tcr vβ21.3 staining as a diagnostic test for multisystem inflammatory syndrome in children : a proof-of-concept study
Levi Hoste
Jef Willems
Evelyn Dhont
Petra Schelstraete
Jo Dehoorne
Kristof Vandekerckhove
Alexandre Belot
Brigitte Bader-Meunier
Christophe Malcus
Simon Tavernier
et al.
C3
Conferentie
2022
2021
A novel non-coding variant in DCLRE1C results in deregulated splicing and induces SCID through the generation of a truncated ARTEMIS protein that fails to support V(D)J recombination and DNA damage repair
Steven Strubbe
Marieke De Bruyne
Ulrich Pannicke
Elien Beyls
Bart Vandekerckhove
Georges Leclercq
Elfride De Baere
Victoria Bordon
Anne Vral
Klaus Schwarz
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2021
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
Paul Bastard
Adrian Gervais
Tom Le Voyer
Jérémie Rosain
Quentin Philippot
Jérémy Manry
Eleftherios Michailidis
Hans-Heinrich Hoffmann
Shohei Eto
Marina Garcia-Prat
et al.
A1
Artikel in een tijdschrift
in
SCIENCE IMMUNOLOGY
2021
Clinical, genetic and immunological evaluation of the type I interferonopathy Aicardi-Goutieres syndrome caused by mutations in RNU7-1
Leslie Naesens
Josephine Nemegeer
Tessa Kerre
Rudi Beyaert
Simon Tavernier
Jonathan Maelfait
Filomeen Haerynck
C3
Conferentie
2021
Congenital defects of phagocytes
Delfien Bogaert
Filomeen Haerynck
Hoofdstuk in een boek
in
Cellular primary immunodeficiencies
2021
Distinct antibody repertoires against endemic human coronaviruses in children and adults
Taushif Khan
Mahbuba Rahman
Fatima Al Ali
Susie S. Y. Huang
Manar Ata
Qian Zhang
Paul Bastard
Zhiyong Liu
Emmanuelle Jouanguy
Vivien Beziat
et al.
A1
Artikel in een tijdschrift
in
JCI INSIGHT
2021
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial
Jozefien Declercq
Karel Van Damme
Elisabeth De Leeuw
Bastiaan Maes
Cedric Bosteels
Simon Tavernier
Stefanie De Buyser
Roos Colman
Maya Hites
Gil Verschelden
et al.
A1
Artikel in een tijdschrift
in
LANCET RESPIRATORY MEDICINE
2021
From your nose to your toes : a review of severe acute respiratory syndrome coronavirus 2 pandemic‒associated pernio
Lisa M. Arkin
John J. Moon
Jennifer M. Tran
Samira Asgari
Cliona O’Farrelly
Edward W. Cowen
Jacqueline W. Mays
Anne Marie Singh
Alessandro Aiuti
Alexandre Belot
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF INVESTIGATIVE DERMATOLOGY
2021
GTF3A mutations in a patient with herpes simplex encephalitis reveals a novel role in viral immunity by transcribing 5S rRNA pseudogenes serving as RIG-I ligands
Leslie Naesens
Santoshi Muppala
Jung-Hyun Lee
Josephine Nemegeer
Dhiraj Acharya
Delfien Bogaert
Michiel van Gent
Jens Staal
Katrien Staes
Veronique Debacker
et al.
C3
Conferentie
2021
Granulomatous–lymphocytic interstitial lung disease : an international research prioritisation
John R. Hurst
S. Hamza Abbas
Heba M. Bintalib
Tiago M. Alfaro
Ulrich Baumann
Siobhan O. Burns
Alison Condliffe
Jesper R. Davidsen
Børre Fevang
Andrew R. Gennery
et al.
A1
Artikel in een tijdschrift
in
ERJ OPEN RESEARCH
2021
Harnessing type I IFN immunity against SARS-CoV-2 with early administration of IFN-β
Donald C. Vinh
Laurent Abel
Paul Bastard
Matthew P. Cheng
Antonio Condino-Neto
Peter K. Gregersen
Filomeen Haerynck
Maria-Pia Cicalese
David Hagin
Pere Soler-Palacín
et al.
Redactioneel materiaal
2021
Immune monitoring in melanoma and urothelial cancer patients treated with anti-PD-1 immunotherapy and SBRT discloses tumor specific immune signatures
Annabel Meireson
Simon Tavernier
Sofie Van Gassen
Nora Sundahl
Annelies Demeyer
Mathieu Spaas
Vibeke Kruse
Liesbeth Ferdinande
Jo Van Dorpe
Benjamin Hennart
et al.
A1
Artikel in een tijdschrift
in
CANCERS
2021
Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort
Levi Hoste
Judith Claus
Simon Schelfhout
Jarno De Craemer
Laurens De Ketelaere
Delfien Bogaert
Carolien Bonroy
Jan Philippé
Julie Willekens
Tessa Kerre
et al.
C3
Conferentie
2021
Individuals with NR5A1 (SF1) mutations and atypical sex development and their asymptomatic family member carriers are at high risk of hyposplenism
Celien Grijp
Simon Tavernier
Jana Neirinck
Maha Abdullhadi-Atwan
Julie Van De Velde
Dorien Baetens
Hannah Verdin
Lieve Morbée
Elfride De Baere
David Zangen
et al.
C3
Conferentie
2021
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations
Julian Thalhammer
Gerhard Kindle
Alexandra Nieters
Stephan Rusch
Mikko R.J. Seppänen
Alain Fische
Bodo Grimbacher
David Edgar
Matthew Buckland
Nizar Mahlaoui
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2021
Integration of genomics and transcriptomics allows the identification of rare DNA damage defects in PID patients with a cancer predisposition
Lynn Backers
Bram Parton
Mattias Van Heetvelde
Marieke De Bruyne
Kim De Leeneer
Simon Tavernier
Anne Vral
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2021
Integration of genomics and transcriptomics to identify DNA damage defects in PID patients prone to cancer
Lynn Backers
Bram Parton
Mattias Van Heetvelde
Marieke De Bruyne
Kim De Leeneer
Anne Vral
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2021
Integration of genomics and transcriptomics to identify DNAdamage defects in PID patients with a cancer predisposition
Lynn Backers
Bram Parton
Mattias Van Heetvelde
Marieke De Bruyne
Kim De Leeneer
Anne Vral
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2021
Missing heritability in Bloom syndrome : First report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene
Lynn Backers
Bram Parton
Marieke De Bruyne
Simon Tavernier
Kris Van Den Bogaert
Bart Lambrecht
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2021
Missing heritability in Bloom syndrome : first report of a deep intronic variant leading to pseudo‐exon activation in the BLM gene
Lynn Backers
Bram Parton
Marieke De Bruyne
Simon Tavernier
Kris Van Den Bogaert
Bart Lambrecht
Filomeen Haerynck
Kathleen Claes
A1
Artikel in een tijdschrift
in
CLINICAL GENETICS
2021
Multisystem inflammatory syndrome in children related to COVID-19 : a systematic review
Levi Hoste
Ruben Van Paemel
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2021
Novel mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF and result in Aicardi-Goutières syndrome with severe end-organ involvement
Leslie Naesens
Josephine Nemegeer
Filip Roelens
Lore Vallaeys
Marije Meuwissen
Katrien Janssens
PATRICK VERLOO
Benson Ogunjimi
Dimitri Hemelsoet
Program for Undiagnosed Rare Diseases (UD-PrOZA)
et al.
C3
Conferentie
2021
Parental experience and emotional well-being in families with a child with a chronic disease during the COVID 19 pandemic
Eline Van Hoecke
Karlien Dhondt
Ann Raes
Stephanie Van Biervliet
Barbara De Moerloose
Sara Van Aken
Filomeen Haerynck
Levi Hoste
Helene Verhelst
Bart Soenens
et al.
C3
Conferentie
2021
Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency
Leslie Naesens
Julie Smet
Simon Tavernier
Petra Schelstraete
Levi Hoste
Stijn Lambrecht
Helene Verhelst
Jutte van der Werff Ten Bosch
Alina Ferster
Sophie Blumental
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2021
SARS-CoV-2–related MIS-C : a key to the viral and genetic causes of Kawasaki disease?
Vanessa Sancho-Shimizu
Petter Brodin
Aurélie Cobat
Catherine M. Biggs
Julie Toubiana
Carrie L. Lucas
Sarah E. Henrickson
Alexandre Belot
Elie Haddad
Kathie Beland
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2021
SeroCovid19 : prospective seroprevalence monitoring reveals substantially reduced SARS-CoV-2 infection rate among tertiary pediatric patients
Levi Hoste
Agnieszka Prytula-Ebels
Jo Dehoorne
Ruth De Bruyne
Stephanie Van Biervliet
KATHLEEN DE WAELE
Petra Schelstraete
Evelyn Maes
Maria Bordon Cueto De Braem
Arnaud Vanlander
et al.
C3
Conferentie
2021
Treatment of multisystem inflammatory syndrome in children
A J McArdle
O Vito
H Patel
E G Seaby
P Shah
C Wilson
C Broderick
R Nijman
A H Tremoulet
D Munblit
et al.
A1
Artikel in een tijdschrift
in
NEW ENGLAND JOURNAL OF MEDICINE
2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19
Takaki Asano
Bertrand Boisson
Fanny Onodi
Daniela Matuozzo
Marcela Moncada-Velez
Majistor Raj Luxman Maglorius Renkilaraj
Peng Zhang
Laurent Meertens
Alexandre Bolze
Marie Materna
et al.
A1
Artikel in een tijdschrift
in
SCIENCE IMMUNOLOGY
2021
‘Nieuwe heren, nieuwe wetten’ : identificatie van een nieuw pediatrisch inflammatoir syndroom in het midden van de SARS-CoV-2-pandemie
Levi Hoste
Simon Tavernier
Filomeen Haerynck
A4
Artikel in een tijdschrift
in
PERCENTIEL (NEDERLANDSE ED.)
2021
2020
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Paul Bastard
Lindsey B. Rosen
Qian Zhang
Eleftherios Michailidis
Hans-Heinrich Hoffmann
Yu Zhang
Karim Dorgham
Quentin Philippot
Jeremie Rosain
Vivien Beziat
et al.
A1
Artikel in een tijdschrift
in
SCIENCE
2020
Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever
Hanne Van Gorp
Linyan Huang
Pedro Henrique Viana Saavedra
Marnik Vuylsteke
Tomoko Asaoka
Giusi Prencipe
Antonella Insalaco
Benson Ogunjimi
Jerold Jeyaratnam
Ilaria Cataldo
et al.
A1
Artikel in een tijdschrift
in
ANNALS OF THE RHEUMATIC DISEASES
2020
Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19
Karel Van Damme
Simon Tavernier
Nele Van Roy
Elisabeth De Leeuw
Jozefien Declercq
Cedric Bosteels
Bastiaan Maes
Marieke De Bruyne
Delfien Bogaert
Victor Bosteels
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2020
Cytokine profiling by multiplex immunoassay as a valuable tool for diagnosis and monitoring patients with autoinflammatory disorders
Levi Hoste
Jo Dehoorne
Peggy Jacques
Steven Callens
Jeroen van der Hilst
Vito Sabato
Benson Ogunjimi
Simon Tavernier
Filomeen Haerynck
C3
Conferentie
2020
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
Vivien Béziat
Simon Tavernier
Yin-Huai Chen
Cindy S. Ma
Marie Materna
Arian Laurence
Jens Staal
Dominik Aschenbrenner
Lisa Roels
Lisa Worley
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2020
EuroFlow standardized approach to diagnostic immunopheneotyping of severe PID in newborns and young children
Tomas Kalina
Marina Bakardjieva
Maartje Blom
Martin Perez-Andres
Barbara Barendregt
Veronika Kanderová
Carolien Bonroy
Jan Philippé
Elena Blanco
Ingrid Pico-Knijnenburg
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2020
Expect the unexpected : clinical case
Delfien Bogaert
Marieke De Bruyne
Frederic Rieux-Laucate
Elfride De Baere
Filomeen Haerynck
C3
Conferentie
2020
First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation
Lynn Backers
Bram Parton
Stephanie Vermeulen
Marieke De Bruyne
Simon Tavernier
Kris Van Den Bogaert
Anne Vral
Ans Baeyens
Filomeen Haerynck
Bart Lambrecht
et al.
C3
Conferentie
2020
First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation
Lynn Backers
Bram Parton
Stephanie Vermeulen
Marieke De Bruyne
Kris Van Den Bogaert
Anne Vral
Ans Baeyens
Simon Tavernier
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2020
GATA2 deficiency and haematopoietic stem cell transplantation : challenges for the clinical practitioner
Delfien Bogaert
Genevieve Laureys
Leslie Naesens
Dominiek Mazure
Marieke De Bruyne
Amy P. Hsu
Maria Bordon Cueto De Braem
Erik Wouters
Simon Tavernier
Bart Lambrecht
et al.
A1
Artikel in een tijdschrift
in
BRITISH JOURNAL OF HAEMATOLOGY
2020
Hematopoietic stem cell transplantation in children with primary immunodeficiencies : a Belgian single center experience
Delfien Bogaert
Catharina Dhooge
Filomeen Haerynck
Maria Bordon Cueto De Braem
C3
Conferentie
2020
Improved standardization of flow cytometry diagnostic screening of primary immunodeficiency by software-based automated gating
Eleni Linskens
AM Diks
Jana Neirinck
M Perez-Andres
Emilie De Maertelaere
MA Berkowska
Tessa Kerre
Mattias Hofmans
A Orfao
van Dongen JJM
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2020
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Qian Zhang
Paul Bastard
Zhiyong Liu
Jérémie Le Pen
Marcela Moncada-Velez
Jie Chen
Masato Ogishi
Ira K. D. Sabli
Stephanie Hodeib
Cecilia Korol
et al.
A1
Artikel in een tijdschrift
in
SCIENCE
2020
Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score
Victoria Katharina Tesch
Hassan Abolhassani
Bella Shadur
Joachim Zobel
Yuliya Mareika
Svetlana Sharapova
Elif Karakoc-Aydiner
Jacques G. Riviere
Marina Garcia-Prat
Nicolette Moes
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
Managing granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders : e-GLILDnet International Clinicians Survey
Annick A. J. M. van de Ven
Tiago M. Alfaro
Alexandra Robinson
Ulrich Baumann
Anne Bergeron
Siobhan O. Burns
Alison M. Condliffe
Borre Fevang
Andrew R. Gennery
Filomeen Haerynck
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2020
Missing heritability in Bloom syndrome : first report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene
Lynn Backers
Bram Parton
Marieke De Bruyne
Simon Tavernier
Kris Van Den Bogaert
Bart Lambrecht
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2020
Missing heritability in Bloom syndrome : first report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene
Lynn Backers
Bram Parton
Marieke De Bruyne
Simon Tavernier
Kris Van Den Bogaert
Bart Lambrecht
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2020
Multisystem inflammatory syndrome in children related to COVID-19 : a systematic review
Levi Hoste
Ruben Van Paemel
Filomeen Haerynck
Preprint
2020
cDNA and targeted RNA sequencing to unravel hidden genetic defects in PID patients with only one-disease related variant in genes with recessive inheritance
Lynn Backers
Marieke De Bruyne
Simon Tavernier
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2020
2019
'Every sweet has its sour' : rare skin lesions in a boy with combined immunodeficiency
Delfien Bogaert
Margo Hagendorens
Marieke De Bruyne
Hilde Lapeere
Annick Covents
Elfride De Baere
Frans De Baets
Filomeen Haerynck
C3
Conferentie
2019
A computational pipeline for the diagnosis of CVID patients
Annelies Emmaneel
Delfien Bogaert
Sofie Van Gassen
Simon Tavernier
Melissa Dullaers
Filomeen Haerynck
Yvan Saeys
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2019
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation
Simon Tavernier
V Athanasopoulos
PATRICK VERLOO
G Behrens
Jens Staal
Delfien Bogaert
Leslie Naesens
Marieke De Bruyne
Sofie Van Gassen
Eef Parthoens
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2019
Assessment of radiation sensitivity in patients with a primary immunodeficiency disease
Anne Vral
Ans Baeyens
Kathleen Claes
Carolien Bonroy
Victoria Bonroy
Elien Beyls
Evi Duthoo
Lynn Backers
Stephanie Vermeulen
Filomeen Haerynck
C3
Conferentie
2019
Congenital myeloperoxidase deficiency caused by a homozygous MPO splice site mutation in a patient with recurrent candida otomastoiditis
Frederic Acke
Delfien Bogaert
Helen Van Hoecke
Katrien Bonte
Carolien Bonroy
Petra Schelstraete
Marieke De Bruyne
Elfride De Baere
Ingeborg Dhooge
Filomeen Haerynck
C3
Conferentie
2019
Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies
Elena Blanco
Martín Pérez-Andrés
Sonia Arriba-Méndez
Cristina Serrano
Ignacio Criado
Lucía Del Pino-Molina
Susana Silva
Ignacio Madruga
Marina Bakardjieva
Catarina Martins
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
GATA2 deficiency and hematopoietic stem cell transplantation : challenges for the clinical practitioner
Delfien Bogaert
Leslie Naesens
Genevieve Laureys
Maria Bordon Cueto De Braem
Erik Wouters
Simon Tavernier
Bart Lambrecht
Filomeen Haerynck
Tessa Kerre
C3
Conferentie
2019
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis
Scott B Drutman
Filomeen Haerynck
Franklin L Zhong
David Hum
Nicholas J Hernandez
Serkan Belkaya
Franck Rapaport
Sarah Jill de Jong
David Creytens
Simon Tavernier
et al.
A1
Artikel in een tijdschrift
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2019
Immune dysregulation with lymphoproliferation progressing to a rare T-cell non-hodgkin lymphoma
Leslie Naesens
Hilde Demuynck
Kristof Cokelaere
Ciel De Vriendt
Delfien Bogaert
Carolien Bonroy
Rik Schrijvers
Filomeen Haerynck
Tessa Kerre
C3
Conferentie
2019
Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort
Levi Hoste
Judith Claus
Simon Schelfhout
Jarno De Craemer
Laurens De Ketelaere
Delfien Bogaert
Carolien Bonroy
Jan Philippé
Julie Willekens
Tessa Kerre
et al.
C3
Conferentie
2019
Pitfalls in diagnosing complement factor I deficiencies : from clinical phenotype to laboratory diagnosis
Leslie Naesens
Julie Smet
Simon Tavernier
Stijn Lambrecht
Tessa Kerre
Johan Van de Walle
Lubka Roumenina
Patrick Stordeur
Filomeen Haerynck
C3
Conferentie
2019
Radiosensitivity analysis in patients with a primary immunodeficiency disease
Anne Vral
Ans Baeyens
Kathleen Claes
Carolien Bonroy
Victoria Bordon
Elien Beyls
Evi Duthoo
Lynn Backers
Stephanie Vermeulen
Filomeen Haerynck
C3
Conferentie
2019
Rare skin lesions in a boy with activated phosphoinositide 3-kinase delta syndrome
Delfien Bogaert
Marieke De Bruyne
Margo Hagendorens
Hilde Lapeere
Annick Covents
Elfride De Baere
Frans De Baets
Filomeen Haerynck
C3
Conferentie
2019
Treatment forms and clinical course of LPS-Responsive beige-like anchor protein deficiency and introduction of the immune deficiency and dysregulation activity (=IDDA) score
Victoria Katharina Tesch
Hassan Abolhassani
Bodo Grimbacher
Arjan Lankaster
Andrew Gennery
Bella Shadur
Polina Stepensky
Yuliya Mareika
Svetlana Sharapova
Elif Karakoc-Aydiner
et al.
C3
Conferentie
2019
X-linked agammaglobulinemia (XLA) : phenotype, diagnosis, and therapeutic challenges around the world
Zeinab A. El-Sayed
Irina Abramova
Juan Carlos Aldave
Waleed Al-Herz
Liliana Bezrodnik
Rachida Boukari
Ahmed Aziz Bousfiha
Caterina Cancrini
Antonio Condino-Neto
Ghassan Dbaibo
et al.
A1
Artikel in een tijdschrift
in
WORLD ALLERGY ORGANIZATION JOURNAL
2019
cDNA and targeted RNA sequencing to unravel hidden genetic defects in PID patients with only one-disease related variant in genes with recessive inheritance
Lynn Backers
Marieke De Bruyne
Simon Tavernier
Filomeen Haerynck
Kathleen Claes
C3
Conferentie
2019
2018
A CARD9 founder mutation disrupts NF-κB signaling by inhibiting BCL10 and MALT1 recruitment and signalosome formation
Marieke De Bruyne
Levi Hoste
Delfien Bogaert
Lien Van den Bossche
Simon Tavernier
Eef Parthoens
Mélanie Migaud
Deborah Konopnicki
Jean Cyr Yombi
Bart Lambrecht
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2018
A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects
Delfien Bogaert
Hye Sun Kuehn
Carolien Bonroy
Katherine R Calvo
Jo Dehoorne
Arnaud Vanlander
Marieke De Bruyne
Urszula Cytlak
Venetia Bigley
Frans De Baets
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2018
A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and overactive TH17 immunity
Marieke De Bruyne
Delfien Bogaert
Koen Venken
Lien Van den Bossche
Carolien Bonroy
Lisa Roels
Simon Tavernier
Els van de Vijver
Ann Driessen
Marielle van Gijn
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2018
Development and validation of an LC tandem MS assay for the quantification of β-lactam antibiotics in the sputum of cystic fibrosis patients
Katrien Forier
Virginie Van Heck
Mieke Carlier
Eva Van Braeckel
Sabine Van daele
Frans De Baets
Petra Schelstraete
Filomeen Haerynck
Veronique Stove
Leen Van Simaey
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2018
Genes at the crossroad of primary immunodeficiencies and cancer
Charlotte Derpoorter
Maria Bordon Cueto De Braem
Genevieve Laureys
Filomeen Haerynck
Tim Lammens
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2018
Ikaros family zinc finger 1 regulates dendritic cell development and function in humans
Urszula Cytlak
Anastasia Resteu
Delfien Bogaert
Hye Sun Kuehn
Thomas Altmann
Andrew Gennery
Graham Jackson
Attila Kumanovics
Karl V Voelkerding
Seraina Prader
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2018
Ikaros family zinc finger 1 regulates dendritic cell development and function in humans
U. Cytlak
A. Resteu
Delfien Bogaert
H. S. Kuehn
T. Altmann
A. Gennery
G. Jackson
A. Kumanovics
Melissa Dullaers
J. Reichenbach
et al.
C3
Conferentie
2018
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies : an international multicenter retrospective study
Federica Barzaghi
Laura Cristina Amaya Hernandez
Benedicte Neven
Silvia Ricci
Zeynep Yesim Kucuk
Jack J Bleesing
Zohreh Nademi
Mary Anne Slatter
Erlinda Rose Ulloa
Anna Shcherbina
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2018
Properdin deficiency in a child presenting with recurrent lower respiratory tract infections
Leen Moens
Katrijn Arts
Giorgia Bucciol
Patrick F. Stordeur
Filomeen Haerynck
Isabelle Meyts
C3
Conferentie
2018
Structural activation of pro-inflammatory human cytokine IL-23 by cognate IL-23 receptor enables recruitment of the shared receptor IL-12Rβ1
Yehudi Bloch
Laura Bouchareychas
Romain Merceron
Katarzyna Skladanowska
Lien Van den Bossche
Sammy Detry
Srinath Govindarajan
Dirk Elewaut
Filomeen Haerynck
Melissa Dullaers
et al.
A1
Artikel in een tijdschrift
in
IMMUNITY
2018
The complex differential diagnosis underlying fungal infections : a clinical practice guideline regarding persistent, recurrent or invasive candidiasis
Levi Hoste
Delfien Bogaert
Marieke De Bruyne
Maria Bordon Cueto De Braem
Petra Schelstraete
Carolien Bonroy
Simon Tavernier
Filomeen Haerynck
C3
Conferentie
2018
When one rare disease hides another : Kartagener syndrome masking FMF
Levi Hoste
Frans De Baets
Sabine Van daele
Petra Schelstraete
Mieke Boon
Marieke De Bruyne
Melissa Dullaers
Frauke Coppieters
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
CLINICAL PEDIATRICS
2018
2017
A CARD9 Turkisch founder mutation disrupts NF-κB signaling by inhibiting Bcl10 recruitment
Marieke De Bruyne
Levi Hoste
Delfien Bogaert
Mélanie Migaud
Deborah Konopnicki
Bart Lambrecht
Rudi Beyaert
Elfride De Baere
Anne Puel
Jean-Christophe Goffard
et al.
C3
Conferentie
2017
A CARD9 founder mutation p.Arg70Trp in Belgian and French patients of Turkish origin with a spectrum of chronic mucocutaneous and invasive fungal infections
Marieke De Bruyne
Delfien Bogaert
Levi Hoste
Mélanie Migaud
Jean-Christophe Goffard
Anne Puel
Elfride De Baere
Filomeen Haerynck
Melissa Dullaers
C3
Conferentie
2017
CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment
Marieke De Bruyne
Delfien Bogaert
Levi Hoste
Mélanie Migaud
Jean-Christophe Goffard
Deborah Konopnicki
Bart Lambrecht
Rudi Beyaert
Elfride De Baere
Anne Puel
et al.
C3
Conferentie
2017
CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment
Marieke De Bruyne
Delfien Bogaert
Levi Hoste
Mélanie Migaud
Jean-Christophe Goffard
Deborah Konopnicki
Bart Lambrecht
Rudi Beyaert
Elfride De Baere
Anne Puel
et al.
C3
Conferentie
2017
CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment
Marieke De Bruyne
Levi Hoste
Delfien Bogaert
Mélanie Migaud
Jean-Christophe Goffard
Deborah Konopnicki
Bart Lambrecht
Rudi Beyaert
Elfride De Baere
Anne Puel
et al.
C3
Conferentie
2017
Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes
Delfien Bogaert
Melissa Dullaers
Hye Sun Kuehn
Bart Leroy
Julie E Niemela
Hans De Wilde
Sarah De Schryver
Marieke De Bruyne
Frauke Coppieters
Bart Lambrecht
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2017
Exercise performance and quality of life in children with cystic fibrosis and mildly impaired lung function : relation with antibiotic treatments and hospitalization
Kristof Vandekerckhove
Michiel Keyzer
Jasper Cornette
Ilse Coomans
Filip Pyl
Frans De Baets
Petra Schelstraete
Filomeen Haerynck
Daniël De Wolf
Sabine Van daele
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2017
Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders : an integrated immunological and genetic approach
Delfien Bogaert
Elfride De Baere
Filomeen Haerynck
Melissa Dullaers
Proefschrift
2017
Molecular genetics of common variable immunodeficiency
Delfien Bogaert
Melissa Dullaers
Elfride De Baere
Filomeen Haerynck
Hoofdstuk in een boek
in
eLS
2017
Screening protocols to monitor respiratory status in primary immunodeficiency disease : findings from a European survey and subclinical infection working group
S. Jolles
S. Sanchez-Ramon
I. Quinti
P. Soler-Palacin
C. Agostini
B. Florkin
L. -J. Couderc
N. Brodszki
A. Jones
H. Longhurst
et al.
A1
Artikel in een tijdschrift
in
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
2017
The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives
Delfien Bogaert
Marieke De Bruyne
Veronique Debacker
Pauline Depuydt
Katleen De Preter
Carolien Bonroy
Jan Philippé
Maria Bordon Cueto De Braem
Bart Lambrecht
Tessa Kerre
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2017
The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives
Delfien Bogaert
Marieke De Bruyne
Veronique Debacker
Pauline Depuydt
Katleen De Preter
Carolien Bonroy
Jan Philippé
Maria Bordon Cueto De Braem
Bart Lambrecht
Tessa Kerre
et al.
C3
Conferentie
2017
To B or not to B matured : a novel IKAROS haploinsufficiency kindred with incomplete penetrance both at clinical and cellular level
Delfien Bogaert
Hye Sun Kuehn
Carolien Bonroy
Katherine Calvo
Jo Dehoorne
Arnaud Vanlander
Marieke De Bruyne
Venetia Bigley
Petra Schelstraete
Frans De Baets
et al.
C3
Conferentie
2017
To B or not to B matured : a novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B cell maturation defects
Delfien Bogaert
Hye Sun Kuehn
Carolien Bonroy
Katherine Calvo
Jo Dehoorne
Arnaud Vanlander
Petra Schelstraete
Marieke De Bruyne
Urszula Cytlak
Venetia Bigley
et al.
C3
Conferentie
2017
2016
CVID, isolated IgG deficiency and isolated IgG subclass deficiency : clinical features and B cell maturation of the Ghent cohort
Delfien Bogaert
Veronique De Backer
Tessa Kerre
Maria Bordon Cueto De Braem
Bart Lambrecht
Karim Vermaelen
Frans De Baets
Elfride De Baere
Melissa Dullaers
Filomeen Haerynck
C3
Conferentie
2016
Chronic and invasive fungal infections in a family with CARD9 deficiency
Ana Alves de Medeiros
EVELYNE LODEWICK
Delfien Bogaert
Filomeen Haerynck
Sabine Van daele
Bart Lambrecht
Sarah Bosma
Laure Vanderdonckt
Olivier Lortholary
Mélanie Migaud
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2016
Chronic and invasive fungal infections in a family with CARD9 deficiency (vol 36, pg 204, 2016)
Ana Karina Alves de Medeiros
EVELYNE LODEWICK
Delfien Bogaert
Filomeen Haerynck
Sabine Van daele
Bart Lambrecht
Sarah Bosma
Laure Vanderdonckt
Olivier Lortholary
Mélanie Migaud
et al.
Correctie
2016
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
Hanne Van Gorp
Pedro Henrique Viana Saavedra
Nathalia Moraes de Vasconcelos
Nina Van Opdenbosch
Lieselotte Vande Walle
Magdalena Matusiak
Giusi Prencipe
Antonella Insalaco
Filip Van Hauwermeiren
Dieter Demon
et al.
A1
Artikel in een tijdschrift
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2016
Genes associated with common variable immunodeficiency: one diagnosis to rule them all?
Delfien Bogaert
Melissa Dullaers
Bart Lambrecht
Karim Vermaelen
Elfride De Baere
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2016
Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype
Julie Toubiana
Satoshi Okada
Julia Hiller
Matias Oleastro
Macarena Lagos Gomez
Juan Carlos Aldave Becerra
Marie Ouachée-Chardin
Fanny Fouyssac
Katta Mohan Girisha
Amos Etzioni
et al.
A1
Artikel in een tijdschrift
in
BLOOD
2016
Inflammasomes in inflammatory disease
Hanne Van Gorp
Pedro Henrique Viana Saavedra
Nathalia Moraes de Vasconcelos
Nina Van Opdenbosch
Lieselotte Vande Walle
Magdalena Matusiak
Filip Van Hauwermeiren
G. Prencipe
Delfien Bogaert
Melissa Dullaers
et al.
C3
Conferentie
2016
JAK2 deficiency as a novel cause of impaired Th17 immunity
Filomeen Haerynck
Delfien Bogaert
Elfride De Baere
Kristof Van Schil
Frauke Coppieters
Marieke De Bruyne
Margot Hagendorens
Tessa Kerre
Frans De Baets
Maria Bordon Cueto De Braem
et al.
C3
Conferentie
2016
Persistent rotavirus diarrhea post-transplant in a novel JAK3-SCID patient after vaccination
Delfien Bogaert
Kristof Van Schil
Tom Taghon
Maria Bordon Cueto De Braem
Carolien Bonroy
Melissa Dullaers
Elfride De Baere
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2016
RC3H1 mutation with increased ICOS expression causes an autoinflammatory syndrome
Filomeen Haerynck
PATRICK VERLOO
Delfien Bogaert
Joél Smet
Arnaud Vanlander
Maria Bordon Cueto De Braem
Helene Verhelst
Rudy Van Coster
Björn Menten
Melissa Dullaers
C3
Conferentie
2016
Recurrent cutaneous abscesses as the presenting manifestation of STAT1 gain-of-function mutation
Levi Hoste
Marieke De Bruyne
Delfien Bogaert
Elfride De Baere
Carolien Bonroy
Petra Schelstraete
Melissa Dullaers
Tom Vercruysse
Filomeen Haerynck
C3
Conferentie
2016
The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology
Delfien Bogaert
Pauline Depuydt
Katleen De Preter
Carolien Bonroy
Jan Philippé
Maria Bordon Cueto De Braem
Tessa Kerre
Bart Lambrecht
Andrea Cerutti
Karim Vermaelen
et al.
C3
Conferentie
2016
When two rare diseases coincide : Kartagener Syndrome and Familial Mediterranean Fever
Levi Hoste
Frans De Baets
Sabine Van daele
Petra Schelstraete
Mieke Boon
Elfride De Baere
Frauke Coppieters
Filomeen Haerynck
C3
Conferentie
2016
2015
A novel Janus kinase 3 (JAK3) mutation in a patient with severe combined immunodeficiency
Delfien Bogaert
Kristof Van Schil
Tom Taghon
Maria Bordon Cueto De Braem
Melissa Dullaers
Elfride De Baere
Filomeen Haerynck
C3
Conferentie
2015
A novel STAT1 mutation in a patient with pneumocystis jiroveci and chronic mucocutaneous candidiasis
Delfien Bogaert
Melissa Dullaers
Jens Staal
Sarah Gerlo
Elien Vandermarliere
Veronique De Backer
Maria Bordon Cueto De Braem
KATHLEEN DE WAELE
Isabelle Meyts
Leen Moens
et al.
C3
Conferentie
2015
Achromobacter xylosoxidans/ruhlandii colonized CF patients have more hospitalisations and IV antibiotic days
Frans De Baets
Petra Schelstraete
Filomeen Haerynck
L Van Simaey
Mario Vaneechoutte
Sabine Van daele
C3
Conferentie
2015
Acquired partial lipodystrophy : a rare clinical presentation of a complement deficiency
Delphine Bogaert
Melissa Dullaers
Johan Vande Walle
Patrick Stordeur
Elke Govaere
Filomeen Haerynck
C3
Conferentie
2015
Colistin and neurotoxicity : recommendations for optimal use in cystic fibrosis patients
Barbara Claus
Sylvie Snauwaert
Filomeen Haerynck
Sabine Van daele
Frans De Baets
Petra Schelstraete
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
2015
Pseudomonas aeruginosa genotyping: predicting transition to chronic colonization in cystic fibrosis patients
Leander Jonckheere
Mario Vaneechoutte
Frans De Baets
Sabine Van daele
Filomeen Haerynck
Leen Van Simaey
Petra Schelstraete
C3
Conferentie
2015
Screening protocols to detect subclinical respiratory infections in PID : findings from a European survey
S. Jolles
S. Sanchez-Ramon
I Quinti
P. Soler-Palacin
C. Agostini
B. Florkin
L-J Couderc
N. Brodszki
A. Jones
H. Longhurst
et al.
C3
Conferentie
2015
2014
A case of dendritic cell, monocyte, B and NK lymphoid deficiency (DCML)
Melissa Dullaers
Tessa Kerre
Frauke Coppieters
Dorine Sichien
Nancy De Cabooter
Veronique Debacker
Reinhart Speeckaert
Paul Coucke
Elias Debaere
Filomeen Haerynck
et al.
C3
Conferentie
2014
A novel Stat1 mutation leading to hyperphosphorylation in a patient with Pneumocystis jjiroveci and chronic mucocutaneous candidiasis
Melissa Dullaers
Jens Staal
Sarah Gerlo
Elien Vandermarliere
V Debacker
Maria Bordon Cueto De Braem
K De Waele
I Meyts
L Moens
X Bossuyt
et al.
C3
Conferentie
2014
ABPA syndrome (ABPAs) in CF : FEV1 decline, infectious exacerbations and BMI before and after the year of diagnosis (index year), a case control study
Frans De Baets
S Wanyama
Linde De Keyzer
Filomeen Haerynck
Petra Schelstraete
M Thomas
Sabine Van daele
C3
Conferentie
2014
Achromobacter xylosoxidans induced bronchiolitis obliterans in cystic fibrosis
Frans De Baets
Petra Schelstraete
Filomeen Haerynck
Stephanie Van Biervliet
Ruth De Bruyne
H Franckx
Sabine Van daele
A1
Artikel in een tijdschrift
in
PEDIATRIC PULMONOLOGY
2014
Acquired partial lipodystrophy : a rare clinical presentation of a complement deficiency
Delfien Bogaert
Melissa Dullaers
Johan Vande Walle
Patrick Stordeur
Elke Govaere
Filomeen Haerynck
C3
Conferentie
2014
Aspergillus nodi in cystic fibrosis (CF) patients: a rare entity: report of two pediatric cases
Petra Schelstraete
Sabine Van daele
Filomeen Haerynck
Frans De Baets
C3
Conferentie
2014
Clinical presentation of hyper-IgE syndrome in a family with impaired IL-22 production and STAT3 phosphorylation
Filomeen Haerynck
Delfien Bogaert
Elfride De Baere
Bart Lambrecht
Karim Vermaelen
Veronique Debacker
Kristof Van Schil
Frans De Baets
Petra Schelstraete
Maria Bordon Cueto De Braem
et al.
C3
Conferentie
2014
FLH type 5 caused by a novel mutation in STXBP2 gene : an unusual cause of failure to thrive and diarrhea in infancy
Filomeen Haerynck
Ruth De Bruyne
Melissa Dullaers
ROSELYNE UWERA
Bert Callewaert
Elfride De Baere
Myriam Van Winckel
Stephanie Van Biervliet
Sebastien van de Velde
Victoria Bordon
C3
Conferentie
2014
Innate immunity in chronic infectious and inflammatory disease
Filomeen Haerynck
Frans De Baets
Bart Loeys
Proefschrift
2014
Lambert-Eaton myasthenic syndrome in a 13-year-old girl with Xp11.22-p11.23 duplication
Sabine Verbeek
Olivier Vanakker
Rudy Mercelis
AF Lipka
Filomeen Haerynck
Melissa Dullaers
PATRICK VERLOO
Rudy Van Coster
Helene Verhelst
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
2014
Pneumococcal antibody levels in children with PID receiving immunoglobulin
David Tuerlinckx
Benoit Florkin
Alina Ferster
Iris De Schutter
Christophe Chantrain
Filomeen Haerynck
Pierre Philippet
Paul Strengers
Ruth Laub
A1
Artikel in een tijdschrift
in
PEDIATRICS
2014
Screening protocols to detect respiratory infections in PID : findings from a European Survey and subclinical infection working group
S. Jolles
S. Sanchez-Ramon
I. Quinti
P. Soler-Palacin
C. Agostini
B. Florkin
L. J. Couderc
N. Brodszki
A. Jones
H. Longhurst
et al.
C3
Conferentie
2014
The European Society for Immunodeficiencies (ESID) registry 2014
B. Grimbacher
[missing] ESID Registry Working Party
Filomeen Haerynck
A1
Artikel in een tijdschrift
in
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
2014
Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID)
Delfien Bogaert
Melissa Dullaers
Filomeen Haerynck
Elfride De Baere
Karim Vermaelen
C3
Conferentie
2014
2013
An unusual cause of failure to thrive and diarrhea in infancy
ROSELYNE UWERA
Filomeen Haerynck
Maria Bordon Cueto De Braem
Stephanie Van Biervliet
Saskia Vande Velde
Myriam Van Winckel
Ruth De Bruyne
C3
Conferentie
2013
Complete factor I deficiency due to dysfunctional factor I with recurrent aseptic meningo-encephalitis
Filomeen Haerynck
Patrick Stordeur
Johan Vande Walle
Rudy Van Coster
Maria Bordon Cueto De Braem
Frans De Baets
Petra Schelstraete
Cédric Javaux
Marie-Rose Bouvry
Véronique Fremeaux-Bacchi
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL IMMUNOLOGY
2013
Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colonized by P. aeruginosa
Petra Schelstraete
Filomeen Haerynck
Frans De Baets
SARAH DESEYNE
Sabine Van daele
A1
Artikel in een tijdschrift
in
JOURNAL OF CYSTIC FIBROSIS
2013
Genetic variations in toll-like receptor pathway and lung function decline in Cystic Fibrosis patients
Filomeen Haerynck
JM Mahachie John
Kristel Van Steen
Petra Schelstraete
Sabine Van daele
Bart Loeys
Mira Van Thielen
I De Canck
Lieve Nuytinck
Frans De Baets
A1
Artikel in een tijdschrift
in
HUMAN IMMUNOLOGY
2013
Misdiagnosis as asphyxiating thoracic dystrophy and CMV-associated haemophagocytic lymphohistiocytosis in Shwachman-Diamond syndrome
Heidi Schaballie
Marleen Renard
Christiane Vermylen
Isabelle Scheers
Nicole Revencu
Luc Regal
David Cassiman
Lieve Sevenants
Ilse Hoffman
Anniek Corveleyn
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2013
2012
Belgian Shwachman-Diamond syndrome cohort update: misdiagnosis as Jeune syndrome and CMV triggerd hemophagocytosis
H Schaballie
M Renard
X Bossuyt
C Vermylen
I Hoffman
I Scheers
N Revencu
G Matthijs
L Sevenants
Maria Bordon Cueto De Braem
et al.
C3
Conferentie
2012
Birdshot-like chorioretinopathy in common variable immunodeficiency
Véronique de Maeyer
Bart Leroy
Tessa Kerre
Liesbeth Ferdinande
Filomeen Haerynck
Frans De Baets
Philippe Kestelyn
A2
Artikel in een tijdschrift
in
RETINAL CASES & BRIEF REPORTS
2012
Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies in paediatric patients with primary immunodeficiency disease (PID) treated with intravenous immunoglobulin (Multigam®)
D Tuerlinckx
B Florkin
I de Schutter
C Chantrain
Filomeen Haerynck
P Philippet
R Laub
A Ferster
C3
Conferentie
2012
Genetic variations in toll-like receptor pathway and lung function decline in cystic fibrosis patients
Filomeen Haerynck
Kristel Van Steen
JM John
Petra Schelstraete
Sabine Van daele
Bart Loeys
M Van Thielen
I De Canck
Frans De Baets
C3
Conferentie
2012
Malacia, inflammation and bronchoalveolar lavage culture in children with persistent respiratory symptoms
Frans De Baets
I De Schutter
C Aarts
Filomeen Haerynck
Sabine Van daele
E De Wachter
A Malfroot
Petra Schelstraete
A1
Artikel in een tijdschrift
in
EUROPEAN RESPIRATORY JOURNAL
2012
Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colonization in cystic fibrosis patients
Filomeen Haerynck
Kristel Van Steen
T Cattaert
Bart Loeys
Sabine Van daele
Petra Schelstraete
Kathleen Claes
M Van Thielen
I De Canck
JM Mahachie John
et al.
A1
Artikel in een tijdschrift
in
HUMAN IMMUNOLOGY
2012
Quantifying total IgG and IgG subclasses (peak and trough) in primary immunodeficiency paediatric patients treated with intravenous immunoglobulin (Multigam®) and relation with serospecific antipneumococcal antibodies
D Tuerlinckx
B Florkin
I de Schutter
C Chantrain
Filomeen Haerynck
P Philippet
R Laub
A Ferster
C3
Conferentie
2012
SCID-like symptoms in a patient with chronic mucocutaneous candidiasis caused by STAT1 mutation
Melissa Dullaers
Maria Bordon Cueto De Braem
K De Waele
I Meyts
L Moens
X Bossuyt
Karim Vermaelen
Bart Lambrecht
F De Baets
Filomeen Haerynck
C3
Conferentie
2012
Successful treatment with sirolimus in patients with refractory autoimmune lymphoproliferative syndrome
Filomeen Haerynck
K Logghe
Maria Bordon Cueto De Braem
B Neven
F Rieux-Laucat
Frans De Baets
C3
Conferentie
2012
2011
Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)
Jana Pachlopnik Schmid
Danielle Canioni
Despina Moshous
Fabien Touzot
Nizar Mahlaoui
Fabian Hauck
Hirokazu Kanegane
Eduardo Lopez-Granados
Ester Mejstrikova
Isabelle Pellier
et al.
A1
Artikel in een tijdschrift
in
BLOOD
2011
Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation
Aude Magerus-Chatinet
Bénédicte Neven
Marie-Claude Stolzenberg
Cécile Daussy
Peter D Arkwright
Nina Lanzarotti
Catherine Schaffner
Sophie Cluet-Dennetiere
Filomeen Haerynck
Gérard Michel
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL INVESTIGATION
2011
Recommended indications for the administration of polyclonal immunoglobulin preparations
M Delforge
CM Farber
P Späth
S Kaveri
T Witte
SA Misbah
R Hübner
Filomeen Haerynck
D Latinne
L Muylle
et al.
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2011
2010
Comparison of culture and qPCR for the detection of Pseudomonas aeruginosa in not chronically infected cystic fibrosis patients
Pieter Deschaght
Petra Schelstraete
Guido Lopes dos Santos Santiago
Leen Van Simaey
Filomeen Haerynck
Sabine Van daele
Elke De Wachter
Anne Malfroot
Patrick Lebecque
Christiane Knoop
et al.
A1
Artikel in een tijdschrift
in
BMC MICROBIOLOGY
2010
Genotype based evaluation of Pseudomonas aeruginosa eradication treatment success in cystic fibrosis patients
Petra Schelstraete
Pieter Deschaght
Leen Van Simaey
Sabine Van daele
Filomeen Haerynck
Mario Vaneechoutte
Frans De Baets
A1
Artikel in een tijdschrift
in
JOURNAL OF CYSTIC FIBROSIS
2010
Milk protein and Oil-Red-O staining of alveolar macrophages in chronic respiratory disease of infancy
Frans De Baets
Claudia Aarts
Sabine Van daele
Filomeen Haerynck
Elke De Wachter
Iris De Schutter
Anne Malfroot
Petra Schelstraete
A1
Artikel in een tijdschrift
in
PEDIATRIC PULMONOLOGY
2010
Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries
Ludovic de Beaucoudrey
Arina Samarina
Jacinta Bustamante
Aurélie Cobat
Stéphanie Boisson-Dupuis
Jacqueline Feinberg
Saleh Al-Muhsen
Lucile Jannière
Yoann Rose
Maylis de Suremain
et al.
A1
Artikel in een tijdschrift
in
MEDICINE
2010
2009
A 475 years-old founder effect involving IL12RB1: a highly prevalent mutation conferring Mendelian susceptibility to mycobacterial diseases in European descendants
J Yancoski
C Rocco
A Bernasconi
M Oleastro
L Bezrodnik
C Vrátnica
Filomeen Haerynck
SD Rosenzweig
A1
Artikel in een tijdschrift
in
INFECTION GENETICS AND EVOLUTION
2009
A missence mutation in complement factor I associated with recurrent aseptic meningoencephalitis
Joke Dehoorne
Filomeen Haerynck
Bart Loeys
Helene Verhelst
F Mascart
Ann Raes
Johan Vande Walle
C3
Conferentie
2009
Genotype based evaluation of eradication treatment success for new Pseudomonas aeruginosa infections in cystic fibrosis patients
Petra Schelstraete
Pieter Deschaght
Leen Van Simaey
Sabine Van daele
Filomeen Haerynck
Mario Vaneechoutte
Frans De Baets
C3
Conferentie
2009
Niet alles wat piept bij kinderen is astma
Filomeen Haerynck
Frans De Baets
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2009
2008
Complement factor B deficiency associated with recurrent asceptic meningitis
Jo Dehoorne
Astrid Raes
Filomeen Haerynck
Ann De Guchtenaere
Johan Vande Walle
Rik Joos
C3
Conferentie
2008
Complement factor B deficiency associated with recurrent asceptic meningitis
Filomeen Haerynck
Petra Schelstraete
Johan Vande Walle
Rudy Van Coster
Maria Bordon Cueto De Braem
F Mascart
Jo Dehoorne
C3
Conferentie
2008
Disseminated Mycobacterium avium Infection in a Patient with a Novel Mutation in the Interleukin-12 Receptor-beta 1 Chain
Filomeen Haerynck
Steve M. Holland
Sergio D. Rosenzweig
Jean-Laurent Casanova
Petra Schelstraete
Frans De Baets
A1
Artikel in een tijdschrift
in
JOURNAL OF PEDIATRICS
2008
Mutation 1623_1624delGCinsTT and IL-12Rb1 deficiency : a mutational founder effect on the most frequently affected gene for Mendelian susceptibility to mycobacterial disease
Judith Yancoski
Carlos Rocco
Andrea Bernasconi
Matias Oteastro
Filomeen Haerynck
Liliana Bezrodnik
Sergio D. Rosenzweig
C3
Conferentie
2008
Severe corticosteroid-dependent asthma in association with eczema and type 1 diabetes mellitus as an early manifestation of the IPEX syndrome: a case report
Filomeen Haerynck
Frans De Baets
Petra Schelstraete
Sabine Van daele
Catharina Dhooge
K De Waele
Maria Bordon Cueto De Braem
C3
Conferentie
2008
2007
Achromobacter xylosoxidans in cystic fibrosis: Prevalence and clinical relevance
Frans De Baets
P SCHELSTRAETE
Sabine Van daele
Filomeen Haerynck
Mario Vaneechoutte
A1
Artikel in een tijdschrift
in
JOURNAL OF CYSTIC FIBROSIS
2007
Limbic encephalitis as presentation of a SAP deficiency
Helene Verhelst
Rudy Van Coster
Nele Bockaert
Genevieve Laureys
Sylvie Latour
A Fischer
Filomeen Haerynck
Redactioneel materiaal
2007
Single nucleotide polymorphisms in genes of the innate immunity in cystic fibrosis patients: Correlation with lung function and pseudomonas aeruginosa colonisation
Filomeen Haerynck
Sabine Van daele
Petra Schelstraete
E DE MEESTER
R ROSSAU
Frans De Baets
C3
Conferentie
2007
2006
Limbic encephalitis as presentation of a SAP deficiency
Helene Verhelst
Rudy Van Coster
N BOCKAERT
Genevieve Laureys
Alexandra Fischer
Filomeen Haerynck
C3
Conferentie
2006
2005
Epidemiology of Pseudomonas aeruginosa in a cystic fibrosis rehabilitation centre
Sabine Van daele
H FRANCKX
Rita Verhelst
Petra Schelstraete
Filomeen Haerynck
I VAN SIMAEY
Geert Claeys
Mario Vaneechoutte
Frans De Baets
A1
Artikel in een tijdschrift
in
EUROPEAN RESPIRATORY JOURNAL
2005
2004
Asphyxiating tracheal bronchogenic cyst
Frans De Baets
Sabine Van daele
Petra Schelstraete
Filomeen Haerynck
Frank Vermassen
C BROERS
A1
Artikel in een tijdschrift
in
PEDIATRIC PULMONOLOGY
2004
1998
Factors influencing long term persistence of sinus rhythm after a first electrical cardioversion for atrial fibrillation
Mattias Duytschaever
Filomeen Haerynck
René Tavernier
Luc Jordaens
A1
Artikel in een tijdschrift
in
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
1998
1997
Changes in the QT interval and its adaptation to rate, assessed with continuous electrocardiographic recordings in patients with ventricular fibrillation, as compared to normal individuals without arrhythmias
René Tavernier
Luc Jordaens
Filomeen Haerynck
E Derycke
Denis Clement
A1
Artikel in een tijdschrift
in
EUROPEAN HEART JOURNAL
1997
1996
A putative tumor suppressor gene involved in Merkel cell carcinoma maps between p58 and D172
Franki Speleman
ML Geerts
Filomeen Haerynck
Bart Dermaut
Nadine Van Roy
C3
Conferentie
1996