Research Explorer

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Researcher

Dirk De Valck

Awards & Distinctions

11 Results

2001

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.

Sofie Van HuffelFilip DelaeiKaren HeyninckDirk De ValckRudi Beyaert

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Inhibition of Tumor Necrosis Factor-induced necrotic cell death by the zinc finger protein A20.

Karen HeyninckGeertrui DeneckerDirk De ValckWalther FiersRudi Beyaert

A1 Journal Article in ANTICANCER RESEARCH

The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.

Karen HeyninckDirk De ValckWim Vanden BergheWim Van CriekingeRoland ContrerasWalther FiersGuy HaegemanRudi Beyaert

A1 Journal Article in JOURNAL OF CELL BIOLOGY

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.

Dirk De ValckDY JINKaren HeyninckMarc Van De CraenRoland ContrerasWalther FiersKT JEANGRudi Beyaert

A1 Journal Article in ONCOGENE

1998

Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies.

Dirk De ValckDominique VercammenWalther FiersRudi Beyaert

A1 Journal Article in JOURNAL OF CELLULAR BIOCHEMISTRY

Identificatie en karakterisering van fosfolipasen en TNF-resistente eiwitten betrokken bij TNF-geïnduceerde celdood en genactivering

Dirk De ValckRudi BeyaertRoland Contreras

1997

Tumour necrosis factor: intracellular mechanism of action

Walther FiersRudi BeyaertElke BooneWim DeclercqEls DecosterDirk De ValckVera GoossensJohan GrootenGuy HaegemanKaren Heyninck et al.

Bookchapter in HIV and cytokines

1993

Tumor necrosis factor cytotoxicity is associated with activation of cellular phospholipases

Dirk De ValckRudi BeyaertFrans Van RoyWalther Fiers

Two pathways of tumor necrosis factor signal transduction: in vitro and in vivo implications

Walther FiersRudi BeyaertPeter BrouckaertAnje CauwelsWim DeclercqDirk De ValckB EveraerdtVera GoossensJohan GrootenGuy Haegeman et al.

1992

Tumor necrosis factor : mechanism of action and its potential for anticancer therapy

W HersRudi BeyaertPeter BrouckaertEls DecosterDirk De ValckB EveraerdtJohan GrootenAnne LenaertsClaude LibertK Schulze-Osthoff et al.

Tumor-necrosis-factor : mechanism of action at the molecular, cellular and in vivo level

Walther FiersRudi BeyaertPeter BrouckaertEls DecosterDirk De ValckBart EveraerdtJohan GrootenAnne LenaertsClaude LibertK. Schulzeosthoff et al.