Research Explorer

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Researcher

Bjorn Criel

Publications & Research Data

Awards & Distinctions

16 Results

2025

Diversity, structure-function relationships and evolution of cell wall-binding domains of staphylococcal phage endolysins

Roberto VázquezDiana Gutierrez FernandezBjorn CrielZoë DezutterYves Briers

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

From design to function : an automation-enabled pipeline for the development of precision lysin therapeutics

Dennis GrimonJens Van LiefferingeLeen Van SimaeyMartijn VerhelstGilles VandermarliereMaria João de Carvalho Maurício da FonsecaBjorn CrielKristof Van EmelenGuy HermansYves Briers

PhaLP 2.0 : a community-oriented database and portal for phage lysin research with new tailored computational tools and metagenomic data

Roberto VázquezAlexandre BoulayVictor NémethEmma CremelieBjorn CrielClovis GaliezElsa RousseauYves Briers

‘Exquisite specificity’, if the context allows : endolysin evolution is a contingent outcome of phage-host molecular landscapes

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielDennis GrimonRémy GoudeseuneJuan Roque Lizasoain VallejoSeila AgúnYves Briers

2024

Dissecting the unknown specificity of cell wall-binding domains of phage endolysins

Roberto VázquezDiana Gutierrez FernandezZoë De ZutterBjorn CrielYves Briers

Lessons learned from a systematic structural-functional characterization of cell wall binding domains (CBDs) from phage endolysins

Roberto VázquezDiana Gutierrez FernandezZoë de ZutterBjorn CrielYves Briers

You get what you test for : the killing effect of phage lysins is highly dependent on buffer tonicity and ionic strength

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielPhilippe De GrooteYves Briers

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

2023

Structural and functional diversity of cell wall binding domains in staphylococcal endolysins

Roberto VázquezDiana Gutierrez FernandezBjorn CrielAna RodríguezPilar GarcíaYves Briers

Structural and functional diversity of staphylococcal cell wall binding domains

Roberto VázquezDiana Gutierrez FernandezZoë DezutterBjorn CrielYves Briers

2022

Exploring PhaLP, an open source portal for Phage Lytic Proteins, to engineer modular enzybiotics against vancomycin-resistant Enterococcus faecalis

Bjorn CrielWim Van CriekingeYves Briers

Exploring PhaLP, an open source portal for Phage Lytic Proteins, to engineer modular enzybiotics against vancomycin-resistant Enterococcus faecalis

Bjorn CrielWim Van CriekingeYves Briers

Machine learning-guided engineering of modular enzybiotics to target vancomycin-resistant Enterococcus faecalis infections of the urinary tract

Bjorn CrielWim Van CriekingeYves Briers

The specific capsule depolymerase of phage PMK34 sensitizes Acinetobacter baumannii to serum killing

Karim Abdelkader Soufi AbdelkaderDiana Gutierrez FernandezAgnieszka ŁątkaDimitri BoeckaertsZuzanna Drulis-KawaBjorn CrielHans GerstmansAmal SafaanAhmed S. KhairallaYasser Gaber et al.

A1 Journal Article in ANTIBIOTICS-BASEL

2021

PhaLP : a database for the study of phage lytic proteins and their evolution

Bjorn CrielSteff TaelmanWim Van CriekingeMichiel StockYves Briers

A1 Journal Article in VIRUSES-BASEL

Predicting bacteriophage hosts based on sequences of annotated receptor-binding proteins

Dimitri BoeckaertsMichiel StockBjorn CrielHans GerstmansBernard De BaetsYves Briers

A1 Journal Article in SCIENTIFIC REPORTS

2018

Synthetic biology of modular endolysins

Hans GerstmansBjorn CrielYves Briers

A1 Journal Article in BIOTECHNOLOGY ADVANCES