Research Explorer

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Researcher

Bart Lambrecht

487 Results

2021

Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation

Nikos OikonomouMartijn SchuijsAntonis ChatzigiagkosAriadne AndroulidakiVassilis AidinisHamida HammadBart LambrechtManolis Pasparakis

A1 Journal Article in MUCOSAL IMMUNOLOGY

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis

[missing] The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working GroupIsabel MurGracia María MateoMaria del Mar GutierrezVirginia PomarNatividad de BenitoNoemí CorbachoSilvia HerreraLucia MillanJessica MuñozJorge MaloufMaria Ema MolasVictor AsensiJuan Pablo HorcajadaVicente EstradaFelix GutierrezFerran TorresJose A Perez-MolinaJesús FortunLuisa M VillarUlla HohenthalHarri MarttilaTytti VuorinenMarika NordbergMika ValtonenMatthew J FrigaultMichael K MansourNaomi J PatelAna FernandesLiam HarveyAndrea S FoulkesBrian C HealyRuta ShahAna Maria BensaciAnn E. WoolleySarah NikiforowNina LinManish SagarHarry ShragerDavid S. HuckinsMatthew AxelrodMichael D PincusJorge FleisherJon LampaPiotr NowakJan C. VesterbackaJohan RasmusonPaul SkorupHelena JanolsKatarina F NiwardKaterina ChatzidionysiouHilmir AsgeirssonÅsa ParkeOla BlennowAnna-Karin SvenssonSoo AlemanAnders SönnerborgJan-Inge HenterAnna Carin HorneFarah Al-BeidhDerek AngusDjillali AnnaneYaseen ArabiAbigail BeaneScott BerryZahra BhimaniMarc BontenCharlotte BradburyFrank BrunkhorstMeredith BuxtonAllen ChengMatt CoveMenno De JongLennie DerdeLise EstcourtHerman GoossensAnthony GordonCameron GreenRashan HaniffaNao IchiharaFrancois LamontagnePatrick LawlerEd LittonJohn MarshallColin McArthurDaniel McAuleyShay McGuinnessBryan McVerryStephanie MontgommeryPaul MounceyAlistair NicholRachael ParkeJane ParkerFelipe ReyesKathryn RowanHiroki SaitoMarlene SantosChris SeymourAlexis TurgeonAnne TurnerWilma van Bentum-PuijkFrank van de VeerdonkSteve WebbRyan ZarychanskiJ Kenneth BaillieRichard BeasleyNichola CooperRobert FowlerJames GaleaThomas HillsAndrew KingSusan MorpethMihai NeteaKayode OgungbenroVille PettilaSteve TongTim UyekiTaryn YoungsteinAlisa HigginsLindsay BerryCarlos SalamaIvan O. RosasBelén Ruiz-AntoránElena Muñez RubioAntonio Ramos MartínezJosé Campos EstebanCristina Avendaño SoláJesus Sanz SanzFrancisco Abad-SantosAzucena Bautista-HernándezLucio García-FraileAna BarriosÁngela Gutiérrez LiarteTamara Alonso PérezSebastian C Rodríguez-GarcíaGina Mejía-AbrilJose Carlos PrietoRafael LeonVIVIANE C. VEIGAPHILLIP SCHEINBERGDANIELLE L.C. FARIASJOÃO G. PRATSALEXANDRE B. CAVALCANTIFLAVIA R. MACHADOREGIS G. ROSAOTÁVIO BERWANGERLUCIANO C.P. AZEVEDORENATO D. LOPESLETICIA K. DOURADOCLAUDIO G. CASTROFERNANDO G. ZAMPIERIALVARO AVEZUMTHIAGO C. LISBOASALOMÓN S.O. ROJASJULIANA C. COELHORODRIGO T. LEITEJULIO CESAR CARVALHOLUIS E.C. ANDRADEALEX R. SANDESMARIA CAROLINA T. PINTÃOSUELI V. SANTOSTHIAGO M.L. ALMEIDAANDRÉ N. COSTAOTAVIO C.E. GEBARAFLAVIO G.R. FREITASEDUARDO S. PACHECODAVID J.B. MACHADOJOSIANE MARTINFABIO G. CONCEIÇÃOSUELLEN R.R. SIQUEIRALUCAS P. DAMIANILUCIANA M. ISHIHARADANIEL SCHNEIDERDENISE DE SOUZAPierre Louis TharauxMatthieu Resche RigonElie AzoulayJacques CadranelJoseph EmmerichMuriel FartoukhBertrand GuidetMarc HumbertKarine LacombeMatthieu MahevasFrédéric PeneValérie Pourchet-MartinezFrédéric SchlemmerAnnick TibiYazdan YazdanpanahMaxime DougadosSerge BureauPeter W HorbyMartin J LandrayKenneth J BaillieMaya H BuchLucy C ChappellJeremy N DaySaul N FaustThomas JakiKatie JefferyEdmund JuszczakWei Shen LimMarion MafhamAlan MontgomeryAndrew MumfordGuy ThwaitesAdeeba KamarulzamanSharifah Faridah Syed OmarSasheela PonnampalavanarRaja Iskandar Syah Raja AzwaPui Li WongAnjanna KukrejaHang Cheng OngHelmi SulaimanSazali BasriRong Xiang NgBushra Megat JohariMeng Li ChongMalinee NeelamegamSyed Mukhtar Syed MansorNurul Syuhada ZulhaimiCheng Siang LeeFrederick AlticeChristina PriceMaricar MalinisMohd Shahnaz HasanChee Kuan WongSuresh ChidambaramAlif Adlan Mohd ThabitBenedict SimFarah Nadiah BidinMohd Abd Hafiz Mohd Abd RahimSujana SaravanamuttuWei Xuan TuangYasmin Mohamed GaniSuvintheran ThangaveluKim Heng TayNur Munirah IbrahimLuqman Alhakim HalidKok Tong TanMohd Noor Azreet MukriMasita AripHui Moon KohSyarifah Nurul Ain Syed BadaruddinLetchumi Raja SurejaGeok Ying ChunJULIAN TORRE-CISNEROSNICOLAS MERCHANTERAFAEL LEONSHEILA CARCELJOSE CARLOS GARRIDOEitan GalunAlex SorianoJosé Antonio MartínezClara CastánRoger ParedesDavid DalmauCristina CarbonellGerard EspinosaPedro CastroJosé MuñózAlex AlmuedoSergio PrietoIván PachecoMark RatainJennifer PisanoMary StrekAyodeji AdegunsoyeTheodore KarrisonJozefien DeclercqKarel Van DammeElisabeth De LeeuwCedric BosteelsBastiaan MaesManu Shankar-HariClaire L. ValePeter J. GodolphinDavid FisherJulian P. T. HigginsFrancesca SpigaJelena SavovicJayne TierneyGabriel BaronJulie S. BenbenishtyLindsay R. BerryNiklas BromanAlexandre Biasi CavalcantiRoos ColmanStefanie De BuyserLennie P. G. DerdePere DomingoSharifah Faridah OmarAna Fernandez-CruzThijs FeuthFelipe GarciaRosario Garcia-VicunaIsidoro Gonzalez-AlvaroAnthony C. GordonRichard HaynesOlivier HerminePeter W. HorbyNora K. HorickKuldeep KumarBart LambrechtMartin J. LandrayLorna LealDavid J. LedererElizabeth LorenziXavier MarietteNicolas MerchanteNor Arisah MisnanShalini V. MohanMichael C. NivensJarmo OksiJose A. Perez-MolinaReuven PizovRaphael PorcherSimone PostmaReena RajasuriarAthimalaipet V. RamananPhilippe RavaudPankti D. ReidAbraham RutgersAranzazu Sancho-LopezTodd B. SetoSumathi SivapalasingamArvinder Singh SoinNatalie StaplinJohn H. StoneGarth W. StrohbehnJonas Sunden-CullbergJulian Torre-CisnerosLarry W. TsaiHubert van HoogstratenTom van MeertenViviane Cordeiro VeigaPeter E. WesterweelSrinivas MurthyJanet V. DiazJohn C. MarshallJonathan A. C. Sterne

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CCR2-and Flt3-dependent inflammatory conventional type 2 dendritic cells are necessary for the induction of adaptive immunity by the human vaccine adjuvant system AS01

Cedric BosteelsKaat FierensSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsCaroline De WolfAurelie ChalonCatherine CollignonHamida HammadArnaud M. DidierlaurentBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Cellular plasticity and heterogeneity in ovarian cancer progression and therapy resistance

Nele LoretGeert BerxPhilippe TummersBart Lambrecht

Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy

Helena Catharine AegerterUrsula SmoleInes HeyndrickxKenneth VerstraeteSavvas SavvidesHamida HammadBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Conceptions of the pathophysiology of happy hypoxemia in COVID-19

Sebastiaan DhontEric DeromEva Van BraeckelPieter DepuydtBart Lambrecht

A1 Journal Article in RESPIRATORY RESEARCH

Coronavirus disease 2019 in patients with inborn errors of immunity : an international study

Isabelle MeytsGiorgia BucciolIsabella QuintiBénédicte NevenAlain FischerElena SeoaneEduardo Lopez-GranadosCarla GianelliAngel Robles-MarhuendaPierre-Yves JeandelCatherine PaillardVijay G. SankaranYesim Yilmaz DemirdagVassilios LougarisAlessandro AiutiAlessandro PlebaniCinzia MilitoVirgil ASH. DalmKissy Guevara-HoyerSilvia Sánchez-RamónLiliana BezrodnikFederica BarzaghiLuis Ignacio Gonzalez-GranadoGrant R. HaymanGulbu UzelLeonardo Oliveira MendonçaCarlo AgostiniGiuseppe SpadaroRaffaele BadolatoAnnarosa SoresinaFrançois VermeulenCedric BosteelsBart LambrechtMichael KellerPeter J. MustilloRoshini S. AbrahamSudhir GuptaAhmet OzenElif Karakoc-AydinerSafa BarisAlexandra FreemanMarco Yamazaki-NakashimadaSelma Scheffler-MendozaSara Espinosa-PadillaAndrew R. GenneryStephen JollesYasmin EspinozaM Cecilia PoliClaire FieschiFabian HauckCharlotte Cunningham-RundlesNizar MahlaouiKlaus WarnatzKathleen E. SullivanStuart G. Tangye

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ILC3s control splenic cDC homeostasis via lymphotoxin signaling

Matthias VanderkerkenAntonio Pires da Silva BaptistaMarco De GiovanniSatoshi FukuyamaRobin BrowaeysCharlotte ScottPaula S. NorrisGerard EberlJames P. Di SantoEric VivierYvan SaeysHamida HammadJason G. CysterCarl F. WareAlexei V. TumanovCarl De TrezBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van LysebettenAlessio MalfantiKim DeswarteKaloian KoynovBianka GolbaTingting YeZifu ZhongSabah KasmiAlexander LamootYong ChenSimon Van HerckBart LambrechtNiek SandersStefan LienenklausSunil A. DavidMaría J. VicentStefaan De KokerBruno De Geest

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Local immune response to food antigens drives meal-induced abdominal pain

Javier Aguilera-LizarragaMorgane V. FlorensMaria Francesca ViolaPiyush JainLisse DecraeckerIris AppeltansMaria Cuende-EstevezNaomi FabreKim Van BeekEluisa PernaDafne BalemansNathalie StakenborgStavroula TheofanousGoele BosmansStephanie U. MondelaersGianluca MatteoliSales Ibiza MartinezCintya Lopez-LopezJosue Jaramillo-PolancoKarel TalaveraYeranddy A. AlpizarThorsten B. FeyerabendHans-Reimer RodewaldRicard FarreFrank A. RedegeldJiyeon SiJeroen RaesChristine BreynaertRik SchrijversCedric BosteelsBart LambrechtScott D. BoydRamona A. HohDeirdre CabooterMaxim NelisPatrick AugustijnsSven HendrixJessica StridRaf BisschopsDavid E. ReedStephen J. VannerAlexandre Denadai-SouzaMira M. WoutersGuy E. Boeckxstaens

A1 Journal Article in NATURE

Missing heritability in Bloom syndrome : First report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene

Lynn BackersBram PartonMarieke De BruyneSimon TavernierKris Van Den BogaertBart LambrechtFilomeen HaerynckKathleen Claes

Missing heritability in Bloom syndrome : first report of a deep intronic variant leading to pseudo‐exon activation in the BLM gene

Lynn BackersBram PartonMarieke De BruyneSimon TavernierKris Van Den BogaertBart LambrechtFilomeen HaerynckKathleen Claes

A1 Journal Article in CLINICAL GENETICS

RNA viruses in the house dust mite Dermatophagoides pteronyssinus, detection in environmental samples and in commercial allergen extracts used for in vivo diagnosis

Jose Cristian Vidal-QuistCarmen VidalFernando EscolarBart LambrechtStephane RombautsPedro Hernandez-Crespo

A1 Journal Article in ALLERGY

Ribosome-targeting antibiotics impair T cell effector function and ameliorate autoimmunity by blocking mitochondrial protein synthesis

Luis AlmeidaAyesha Dhillon-LaBrooyCarla N. CastroNigatu AdossaGuilhermina M. CarricheMelanie GuderianSaskia LippensSven DennerleinChristina HesseBart LambrechtLuciana BerodLeif SchauserBruce R. BlazarMarkus KalesseRolf MuellerLuis F. MoitaTim Sparwasser

A1 Journal Article in IMMUNITY

Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Anne HuppertsbergLeonard KapsZifu ZhongSascha SchmittJudith StickdornKim DeswarteFrancis CombesChristian CzyschJana De VriezeSabah KasmiNiklas ChoteschovskyAdrian KlefenzCarolina Medina-MontanoPia WinterwerberChaojian ChenMatthias BrosStefan LienenklausNiek SandersKaloian KoynovDetlef SchuppanBart LambrechtSunil A. DavidBruno De GeestLutz Nuhn

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Sonia JangraJana De VriezeAngela ChoiRaveen RathnasingheGabriel LaghlaliAnnemiek UvynSimon Van HerckLutz NuhnKim DeswarteZifu ZhongNiek SandersStefan LienenklausSunil A. DavidShirin StrohmeierFatima AmanatFlorian KrammerHamida HammadBart LambrechtLynda CoughlanAdolfo García‐SastreBruno De GeestMichael Schotsaert

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Surgery in nasal polyp patients : outcome after a minimum observation of 10 years

Stephan VlaminckFrederic AckeEmmanuel ProkopakisKato SpelemanHideyuki KawauchiJean-Christophe van CutsemPeter HellingsMark JorissenSven SeysClaus BachertThibaut Van ZeleBart LambrechtPhilippe Gevaert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

The basic immunology of asthma

Hamida HammadBart Lambrecht

A1 Journal Article in CELL

The pharmacology of the prostaglandin D-2 receptor 2 (DP2) receptor antagonist, fevipiprant

Chris BrightlingSwarupa KulkarniBart LambrechtDavid SandhamMarkus WeissPablo Altman

A1 Journal Article in PULMONARY PHARMACOLOGY & THERAPEUTICS

The role of DC subsets in respiratory viral infections and vaccination : a case of mistaken identity

Cedric BosteelsBart LambrechtHamida Hammad

2020

Adult chronic rhinosinusitis

Claus BachertBradley MarpleRodney J. SchlosserClaire HopkinsRobert P. SchleimerBart LambrechtBarbara M. BrokerTanya LaidlawWoo-Jung Song

A1 Journal Article in NATURE REVIEWS DISEASE PRIMERS

An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells

Sheena C. KerrJeanmarie R. GonzalezJulia SchaninMichael C. PetersBart LambrechtEmily C. BrockAnnabelle CharbitK. Mark AnselBradford A. YoungbloodJohn V. Fahy

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCedric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor BosteelsLevi HosteLeslie NaesensP MaesA GrifoniD WeiskopfA SettePieter DepuydtEva Van BraeckelFilomeen HaerynckBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Elien GevaertTim DelemarreJoyceline De VolderNan ZhangGabriële HoltappelsNatalie De RuyckEmma PerssonInes HeyndrickxKenneth VerstraeteHelena Catharine AegerterHans NauwynckSavvas SavvidesBart LambrechtClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clarifying the translational potential of B-I09

Juan R. Del ValleBrian C. BettsXue-Zhong YuSophie JanssensBart LambrechtM. Celeste SimonChih-Chi Andrew Hu

A1 Journal Article in NATURE CHEMICAL BIOLOGY

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome

Vivien BéziatSimon TavernierYin-Huai ChenCindy S. MaMarie MaternaArian LaurenceJens StaalDominik AschenbrennerLisa RoelsLisa WorleyKathleen ClaesLisa GartnerLisa A. KohnMarieke De BruyneKlaus Schmitz-AbeLouis-Marie CharbonnierSevgi KelesJustine NammourNatasha VladikineMajistor Raj Luxman Maglorius RenkilarajYoann SeeleuthnerMélanie MigaudJérémie RosainMohamed JeljeliBertrand BoissonEva Van BraeckelJill A. RosenfeldHongzheng DaiLindsay C. BurrageDavid R. MurdockBart LambrechtVéronique Avettand-FenoelTiphanie P. VogelCharles R. EstherSule HaskologluFigen DoguPeter CiznarDavid BoutboulMarie Ouachée-ChardinJean AmouretteMarie-Noëlle LebrasClément GauvainColas TcherakianAydan IkinciogullariRudi BeyaertLaurent AbelJoshua D. MilnerBodo GrimbacherLouis-Jean CoudercManish J. ButteAlexandra F. FreemanÉmilie CatherinotClaire FieschiTalal A. ChatilaStuart G. TangyeHolm H. UhligFilomeen HaerynckJean-Laurent CasanovaAnne Puel[missing] Undiagnosed Diseases Network

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation

Lynn BackersBram PartonStephanie VermeulenMarieke De BruyneSimon TavernierKris Van Den BogaertAnne VralAns BaeyensFilomeen HaerynckBart LambrechtKathleen Claes

GATA2 deficiency and haematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertGenevieve LaureysLeslie NaesensDominiek MazureMarieke De BruyneAmy P. HsuMaria Bordon Cueto De BraemErik WoutersSimon TavernierBart LambrechtElfride De BaereFilomeen HaerynckTessa Kerre

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Human lung conventional dendritic cells orchestrate lymphoid neogenesis during chronic obstructive pulmonary disease

Thomas NaessensYannick MoriasEva HamrudUlf GehrmannRamachandramouli BudidaJohan MattssonTina BakerGabriel SkogbergElisabeth IsraelssonKristofer ThornMartijn SchuijsBastian AngermannFaye MelvilleKarl J. StaplesDanen M. CunoosamyBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection

Cedric BosteelsKatrijn NeytManon VanheerswynghelsMary van HeldenDorine SichienNincy DebeufSofie De PrijckVictor BosteelsNiels VandammeLiesbet MartensYvan SaeysEls LouagieManon LesageDavid L. WilliamsShiau-Choot TangJohannes U. MayerFranca RoncheseCharlotte ScottHamida HammadMartin GuilliamsBart Lambrecht

A1 Journal Article in IMMUNITY

Missing heritability in Bloom syndrome : first report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene

Lynn BackersBram PartonMarieke De BruyneSimon TavernierKris Van Den BogaertBart LambrechtFilomeen HaerynckKathleen Claes

Missing heritability in Bloom syndrome : first report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene

Lynn BackersBram PartonMarieke De BruyneSimon TavernierKris Van Den BogaertBart LambrechtFilomeen HaerynckKathleen Claes

Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles

Bi WangSimon Van HerckYong ChenXiangyang BaiZifu ZhongKim DeswarteBart LambrechtNiek SandersStefan LienenklausHans W. ScheerenSunil A. DavidFabian KiesslingTwan LammersBruno De GeestYang Shi

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Publisher correction : Zeb2 drives invasive and microbiota-dependent colon carcinoma

Karolina SlowickaIoanna PettaGillian BlanckeEsther HosteEmilie DumasMozes SzeHanna-Kaisa VikkulaEnrico RadaelliJody J. HaighSven JonckheereJoachim TaminauNiels VandammeAndy WullaertEugene TulchinskyDavid NittnerPieter Van VlierbergheGert De HertoghPamela BaldinEmre EtliogluPratyaksha WirapatiLouis BoonBart LambrechtChris CallewaertSabine TejparSteven GoossensGeert BerxLars VereeckeGeert van Loo

Rbm7 in structural cells : a NEAT way to control fibrosis

Hamida HammadBart Lambrecht

Editorial material

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial

Cedric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren WillaertLaura BolleYuri VanbiervlietJana DecuypereFrederick LibeerStefaan VandecasteeleIsabelle PeeneBart Lambrecht

U Journal Article in TRIALS

Short-term preoperative protein restriction attenuates vein graft disease via induction of cystathionine γ-lyase

Kaspar M TrochaPeter KipMing TaoMichael R MacArthurJ Humberto Treviño-VillarrealAlban LongchampWendy ToussaintBart LambrechtMargreet R de VriesPaul H A QuaxJames R MitchellC Keith Ozaki

A1 Journal Article in CARDIOVASCULAR RESEARCH

Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine

Sonia JangraJana De VriezeAngela ChoiRaveen RathnasingheGabriel LaghlaliAnnemiek UvynSimon Van HerckLutz NuhnKim DeswarteZifu ZhongNiek SandersStefan LienenklausSunil DavidShirin StrohmeierFatima AmanatFlorian KrammerHamida HammadBart LambrechtLynda CoughlanAdolfo García-SastreBruno De GeestMichael Schotsaert

TAO-kinase 3 governs the terminal differentiation of conventional dendritic cells

Matthias VanderkerkenBastiaan MaesLana VandersarrenWendy ToussaintKim DeswarteManon VanheerswynghelsPhilippe PouliotLiesbet MartensSofie Van GassenConnie M. ArthurMargaret E. KirklingBoris ReizisDaniel ConradSean StowellHamida HammadBart Lambrecht

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization

Zan LiHwanhee OhMichelle CungSofia Jenia MarquezJun SunHamida HammadSophie JanssensPhilippe PouliotBart LambrechtYeon-Suk YangJae-Hyuck ShimMatthew B. Greenblatt

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The global response to the COVID-19 pandemic : how have immunology societies contributed?

Faith OsierJenny P. Y. TingJohn FraserBart LambrechtMarta RomanoRicardo T. GazzinelliKarina R. BortoluciDario S. ZamboniArne N. AkbarJennie EvansDoug E. BrownKamala D. PatelYuzhang WuAna B. PerezOliver PerezThomas KamradtChristine FalkMira Barda-SaadAmiram ArielAngela SantoniFrancesco AnnunziatoMarco A. CassatellaHiroshi KiyonoValeriy ChereshnevAlioune DieyeMoustapha MbowBabacar MbengueMaguette D. S. NiangMelinda Suchard

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

The pathophysiology of 'happy' hypoxemia in COVID-19

Sebastiaan DhontEric DeromEva Van BraeckelPieter DepuydtBart Lambrecht

A1 Journal Article in RESPIRATORY RESEARCH

Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice

Heleen VromanDenise van UdenIngrid M. BergenJennifer A.C. van HulstMelanie LukkesGeert van LooBjörn E. ClausenLouis BoonBart LambrechtHamida HammadRudi W. HendriksMirjam Kool

A1 Journal Article in ALLERGY

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial

Bastiaan MaesCedric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren WillaertLaura BolleYuri VanbiervlietJana DecuypereFrederick LibeerStefaan VandecasteeleIsabelle PeeneBart Lambrecht

U Journal Article in TRIALS

Wnt and Hippo pathways in regulatory T cells : a NOTCH above in asthma

Hamida HammadBart Lambrecht

Editorial material

Zeb2 drives invasive and microbiota-dependent colon carcinoma

Karolina SlowickaIoanna PettaGillian BlanckeEsther HosteEmilie DumasMozes SzeHanna-Kaisa VikkulaEnrico RadaelliJody J. HaighSven JonckheereJoachim TaminauNiels VandammeAndy WullaertEugene TulchinskyDavid NittnerPieter Van VlierbergheGert De HertoghPamela BaldinEmre EtliogluPratyaksha WirapatiLouis BoonBart LambrechtChris CallewaertSabine TejparSteven GoossensGeert BerxLars VereeckeGeert van Loo

A2 Journal Article in NATURE CANCER

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV) : a structured summary of a study protocol for a randomised controlled trial

Jozefien DeclercqCedric BosteelsKarel Van DammeElisabeth De LeeuwBastiaan MaesAns VandecauterStefanie VermeerschAnja DelporteBénédicte DemeyereMarnik VuylstekeMarianna LallaTrevor SmartLaurent DetalleRené BouwJohannes StrefferThibo DegeeterMarie VergotteTanguy GuisezEva Van BraeckelCatherine Van Der StraetenBart Lambrecht

A1 Journal Article in TRIALS

2019

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon TavernierV AthanasopoulosPatrick VerlooG BehrensJens StaalDelfien BogaertLeslie NaesensMarieke De BruyneSofie Van GassenEef ParthoensJ EllyardJ CappelloLX MorrisHanne Van GorpGert Van IsterdaelYvan SaeysMohamed LamkanfiPetra SchelstraeteJo DehoorneMaria Bordon Cueto De BraemRudy Van CosterBart LambrechtBjörn MentenRudi BeyaertCG VinuesaV HeissmeyerMelissa DullaersFilomeen Haerynck

A1 Journal Article in NATURE COMMUNICATIONS

A synthetic, transiently thermoresponsive homopolymer with UCST behaviour within a physiologically relevant window

Zhiyue ZhangHui LiSabah KasmiSimon Van HerckKim DeswarteBart LambrechtRichard HoogenboomLutz NuhnBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antigen-presenting dendritic cells

Bart LambrechtHamida Hammad

Bookchapter in Middleton's allergy : principles & practice

Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells

Annemiek UvynRuben De CoenOlivier De WeverKim DeswarteBart LambrechtBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

Developing and benchmarking methods for analysing transcriptomics data

Wouter SaelensYvan SaeysBart Lambrecht

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

Jeanne-Marie PerotinJames PR SchofieldSusan J WilsonJonathan WardJoost BrandsmaFabio StrazzeriAruna BansalXian YangAnthony RoweJulie CorfieldRene LutterDominick E ShawPer S BakkeMassimo CarusoBarbro DahlenStephen J FowlerIldiko HorvathPeter HowarthNorbert KrugPaolo MontuschiMarek SanakThomas SandstromKai SunIoannis PandisCharles AuffrayBertrand De MeulderDiane LefaudeuxJohn H RileyAna R SousaSven-Erik DahlenIan M AdcockKian Fan ChungPeter J SterkPaul J SkippJane E CollinsDonna E DaviesRatko DjukanovicIM AdcockH AhmedC AuffrayP BakkeAT BanssalF BaribaudS BatesEH BelJ BiglerH BisgaardMJ BoedigheimerK BonnelykkeJ BrandsmaP BrinkmanE BucchioniD BurgA BushM CarusoA ChaiboonchoeP ChanezKF ChungCH ComptonJ CorfieldA D'AmicoSE DahlenB De MeulderR DjukanovicVJ ErpenbeckD ErzenK FichtnerN FitchLJ FlemingE FormaggioSJ FowlerU FreyT GeiserY GuoS HashimotoJ HaughneyG HedlinPW HekkingT HigenbottamJM HohlfeldC HolwegI HorvathP HowarthAJ JamesR KnowlesAJ KnoxN KrugD LefaudeuxMJ LozaR LutterS MasefieldJG MatthewsA MazeinA MeiserRJM MiddelveldM MiralpeixP MontuschiN MoresCS MurrayJ MusialD MylesL PahusI PandisS PavlidisP PowellG PraticoM Puig VallsN RaoJ RileyG. RobertsA RoweT SandstromW SeiboldA SelbyDE ShawF SingerPJ SkippAR SousaPJ SterkK SunB ThorntonWM van AalderenM van GeestJ VestboNH VissingAH WagenerSS WagersZ WeiszhartCE WheelockSJ WilsonAntonios AliprantisDavid AllenKjell AlvingP BadorrekDavid BalgomaS BallereauClair BarberManohara Kanangana BatuwitageAn BautmansA BeddingAF BehndigJorge BeletaA BerglindA BertonG BochenekA BraunD CampagnaL CarayannopoulosC CasaultaRomanas ChaleckisB DahlenT DavisonJ De AlbaI De LepeleireT DekkerI DelinP DennisonA DijkhuisP DodsonK DysonJ EdwardsL El HadjamR EmmaM EricssonC FaulenbachBreda FloodG GalffyH GallartD GarissiJ. GentM Gerhardsson de VerdierD GibeonCristina GomezK GoveE Guillmant-FarryE HenrikssonL HewittU HodaRichard HuS HuX HuE JeyasinghamK JohnsonN JullianEJ KenningtonD KerryG KerryM KlueglichH KnobelJohan KolmertJR KonradsenM KotsKosmas KretsosL KruegerS KuoM KupczykBart LambrechtA-S LantzChristopher LarminieLX LarssonP LatzinN LazarinisN LemonnierS Lone-LatifLA LoweA MantaL MarouzetJ MartinC MathonL McEvoyS MeahA Menzies-GowL MetcalfM MikusP MonkS NazK NethingB NicholasU NihlenPeter NilssonR NivenB NordlundS NsubugaJ OstlingA PacinoS PalkonenJ PelletG PennazzaA PetrenS PinkC PisonA PostleM Rahman-AminL RavanettiE RayS ReinkeL ReynoldsK RiemannMartine RobberechtsJP RochaC RossiosK RussellM RutgersG SantiniM SantonincoM SaqiC SchoelchJPR SchofieldS ScottN SehgalM SjodinB SmidsCaroline SmithJ SmithKM SmithP SodermanA SogbessanF SpycherD StaykovaS StephanJ StokholmK StrandbergM SuntherM SzentkeresztyL TamasiK TariqJ-O ThorngrenJonathan ThorsenS ValenteMarianne van de PolCM van DrunenJ Van EyllJ VersnelA VinkC von GarnierA VyasF WaldS WalkerJ WardK WetzelC WiegmanS WilliamsX YangE YeyasinghamW YuW ZetterquistZ ZolkipliAH ZwindermanJ-B PrinsH EvansM PuhlL BuzermanieneV HudsonL BondG WiddershovenA RobertsD SuppleD HamerlijnckJ NegusJ KamphuisL SergisonL VisintinS OnsteinW MacNeeR BernardiniLouis BontP-A WecksellP de BoerM GahlemannR SigmundAleksandra DraperNeil Gozzard

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

From ER stress to T cell biology : IRE1 signaling and TAOK3 function

Lana VandersarrenSophie JanssensBart Lambrecht

GATA2 deficiency and hematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertLeslie NaesensGenevieve LaureysMaria Bordon Cueto De BraemErik WoutersSimon TavernierBart LambrechtFilomeen HaerynckTessa Kerre

How a farming environment protects from atopy

Julie DeckersBart LambrechtHamida Hammad

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

IL-33trap is a novel IL-33-neutralizing biologic that inhibits allergic airway inflammation

Aurora Holgado MunozHarald BraunElien Van NuffelSammy DetryMartijn SchuijsKim DeswarteKarl VergoteMira HaegmanGriet BaudeletJurgen HaustraeteHamida HammadBart LambrechtSavvas SavvidesInna AfoninaRudi Beyaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy

Cristina Gil-CruzChristian Perez-ShibayamaAngelina De MartinFrancesca RonchiKatrien Van Der BorghtRebekka NiedererLucas OnderMechthild LutgeMario NovkovicVeronika NindlGustavo RamosMarkus ArnoldiniEmma MC SlackValerie Boivin-JahnsRoland JahnsMadeleine WyssCatherine MooserBart LambrechtMicha T MaederHans RickliLukas FlatzUrs ErikssonMarkus B GeukingKathy D MccoyBurkhard Ludewig

A1 Journal Article in SCIENCE

Molecular interactions controlling immune homeostasis in the marginal zone

Matthias VanderkerkenBart LambrechtTessa Kerre

ORMDL3 in the regulation of sphingolipid synthesis and in the pathogenesis of allergic asthma

Nincy DebeufBart LambrechtSophie Janssens

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

Jana De VriezeBenoit LouageKim DeswarteZifu ZhongRuben De CoenSimon Van HerckLutz NuhnCamilla Kaas FrichAlexander N ZelikinStefan LienenklausNiek SandersBart LambrechtSunil A DavidBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Professional and 'amateur' antigen-presenting cells in type 2 immunity

Martijn SchuijsHamida HammadBart Lambrecht

A1 Journal Article in TRENDS IN IMMUNOLOGY

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

Eline HaspeslaghManon VanheerswynghelsKim DeswarteJustine Van MoorleghemAlain JacquetBart LambrechtHamida Hammad

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Emma PerssonKenneth VerstraeteInes HeyndrickxElien GevaertHelena Catharine AegerterJean-Michel PercierKim DeswarteKoen VerschuerenAnn DansercoerDelphine GrasPascal ChanezClaus BachertAmanda GonçalvesHanne Van GorpHans De HaardChristophe BlanchetotMichael SaundersHamida HammadSavvas SavvidesBart Lambrecht

A1 Journal Article in SCIENCE

Pulmonary immunomodulation of house dust mite-induced allergic asthma

Eline HaspeslaghHamida HammadBart Lambrecht

Regulators of A20 (TNFAIP3) : new drug-able targets in inflammation

G MomtaziBart LambrechtJR NaranjoBC Schock

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells

Christopher Andrew TibbittJulian Mario StarkLiesbet MartensJunjie MaJeff Eron MoldKim DeswarteGanna OliynykXiaogang FengBart LambrechtPieter De BleserSusanne NylenHamida HammadMarie Arsenian HenrikssonYvan SaeysJonathan Marie Coquet

A1 Journal Article in IMMUNITY

Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche

Johnny BonnardelWouter T'JonckDjoere GaublommeRobin BrowaeysCharlotte ScottLiesbet MartensBavo VannesteSofie De PrijckSergei A NedospasovAnna KremerEvelien Van HammePeter BorghgraefWendy ToussaintPieter De BleserInge MannaertsAlain BeschinLeo A van GrunsvenBart LambrechtTom TaghonSaskia LippensDirk ElewautYvan SaeysMartin Guilliams

A1 Journal Article in IMMUNITY

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

Nincy DebeufAssem ZhakupovaRegula SteinerSofie Van GassenKim DeswarteFarzaneh FayazpourJustine Van MoorleghemKarl VergoteBenjamin PavieKelly LemeireHamida HammadThorsten HornemannSophie JanssensBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The cytokines of asthma

Bart LambrechtHamida HammadJohn V. Fahy

A1 Journal Article in IMMUNITY

The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF

Jessica VettersMary van HeldenSigrid WahlenSimon TavernierArne MartensFarzaneh FayazpourKarl VergoteManon VanheerswynghelsKim DeswarteJustine Van MoorleghemSofie De PrijckNozomi TakahashiPeter VandenabeeleLouis BoonGeert van LooEric VivierBart LambrechtSophie Janssens

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2018

A CARD9 founder mutation disrupts NF-κB signaling by inhibiting BCL10 and MALT1 recruitment and signalosome formation

Marieke De BruyneLevi HosteDelfien BogaertLien Van den BosscheSimon TavernierEef ParthoensMélanie MigaudDeborah KonopnickiJean Cyr YombiBart LambrechtSabine Van daeleAna Alves de MedeirosLieve BrochezRudi BeyaertElfride De BaereAnne PuelJean-Laurent CasanovaJean-Christophe GoffardSavvas SavvidesFilomeen HaerynckJens StaalMelissa Dullaers

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

A bispecific antibody strategy to target multiple type 2 cytokines in asthma

Marie GodarKim DeswarteKarl VergoteMichael SaundersHans de HaardHamida HammadChristophe BlanchetotBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A pathophysiological role of PDE3 in allergic airway inflammation

Jan BeuteMelanie LukkesEwout P KoekoekHedwika NastitiKeerthana GaneshMarjolein JW de BruijnSteve HockmanMenno van NimwegenGert-Jan BraunstahlLouis BoonBart LambrechtVince C ManganielloRudi W HendriksAlex Kleinjan

A1 Journal Article in JCI INSIGHT

Antigen presentation unfolded : identifying convergence points between the UPR and antigen presentation pathways

Fabiola OsorioBart LambrechtSophie Janssens

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Characterization of a lung epithelium specific E-cadherin knock-out model : implications for obstructive lung pathology

S PostIH HeijinkL HesseHK KooF ShaheenM FouadiVNS KuchibhotlaBart LambrechtAJM Van OosterhoutTL HackettMC Nawijn

A1 Journal Article in SCIENTIFIC REPORTS

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De CauwerJonathan ThommisMarnik VuylstekeJan TavernierBart LambrechtHamida HammadKarolien De Bosscher

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dendritic cells in inflammatory disease

Bart LambrechtMartin GuilliamsHamida Hammad

Bookchapter in Inflammation : from molecular and cellular mechanisms to the clinic

Development of novel multifunctional antibodies to treat asthma

Marie GodarBart LambrechtChristophe Blanchetot

Eicosanoid control over antigen presenting cells in asthma

Nincy DebeufBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Exploring the influence of N-glycosylation on allergen-specific immunotherapy

Charlot De WachterNico CallewaertBart Lambrecht

FRET monitoring of intracellular ketal hydrolysis in synthetic nanoparticles

Lutz NuhnSimon Van HerckAndreas BestKim DeswarteMaria KokkinopoulouIngo LieberwirthKaloian KoynovBart LambrechtBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

FcRn is mother's milk to allergen tolerance

Editorial material

FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy

Margot BeringsPhilippe GevaertNatalie De RuyckLara DeryckeGabriële HoltappelsC PiletteClaus BachertBart LambrechtMelissa Dullaers

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Heart macrophages and dendritic cells in sickness and in health : a tale of a complicated marriage

Katrien Van Der BorghtBart Lambrecht

A1 Journal Article in CELLULAR IMMUNOLOGY

House dust mite allergic rhinitis : a novel take on diagnosis and treatment

Margot BeringsPhilippe GevaertMelissa DullaersBart Lambrecht

Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue

Euna YooAlex CD SalyerMichael JH BrushYupeng LiKathryn L TrautmanNikunj M ShuklaAns De BeuckelaerStefan LienenklausKim DeswarteBart LambrechtBruno De GeestSunil A David

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation

Katja ObiegloMartijn SchuijsArifa Ozir-FazalalikhanFrank OttoYolanda van WijckLouis BoonBart LambrechtChristian TaubeHermelijn H Smits

A1 Journal Article in PARASITE IMMUNOLOGY

Isolation of conventional murine lung dendritic cell subsets

Cedric BosteelsBart LambrechtHamida Hammad

A2 Journal Article in CURRENT PROTOCOLS IN IMMUNOLOGY

KIRA1 and ORESARA1 terminate flower receptivity by promoting cell death in the stigma of Arabidopsis

Zhen GaoAnna DanevaYuliya SalanenkaMatthias Van DurmeMarlies HuysmansZongcheng LinFreya De WinterSteffen VannesteMansour KarimiJan Van de VeldeKlaas VandepoeleDavy Van de WalleKoen DewettinckBart LambrechtMoritz Nowack

A1 Journal Article in NATURE PLANTS

Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates

Simon Van HerckKim DeswarteLutz NuhnZifu ZhongJoão Portela CataniYupeng LiNiek SandersStefan LienenklausStefaan De KokerBart LambrechtSunil A DavidBruno De Geest

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells

Katrien Van Der BorghtCharlotte ScottLiesbet MartensDorine SichienGert Van IsterdaelVeronika NindlYvan SaeysLouis BoonBurkhard LudewigThierry GillebertBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses

Lutz NuhnStefaan De KokerSandra Van LintZifu ZhongJoão Portela CataniFrancis CombesKim DeswarteYupeng LiBart LambrechtStefan LienenklausNiek SandersSunil A DavidJan TavernierBruno De Geest

A1 Journal Article in ADVANCED MATERIALS

Osteopontin promotes protective antigenic tolerance against experimental allergic airway disease

Themis AlissafiEvangelia KourepiniDavina C. M. SimoesNikolaos PaschalidisMaria AggelakopoulouTim SparwasserLouis BoonHamida HammadBart LambrechtVily Panoutsakopoulou

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Personalized medicine with biologics for severe type 2 asthma : current status and future prospects

Marie GodarChristophe BlanchetotHans de HaardBart LambrechtGuy Brusselle

A1 Journal Article in MABS

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Lutz NuhnLien Van HoeckeKim DeswarteBert SchepensYupeng LiBart LambrechtStefaan De KokerSunil A DavidXavier SaelensBruno De Geest

A1 Journal Article in BIOMATERIALS

Response to Orlova et al. 'Science not art: statistically sound methods for identifying subsets in multi-dimensional flow and mass cytometry data sets'

Yvan SaeysSofie Van GassenBart Lambrecht

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

Role of NKp46⁺ natural killer cells in house dust mite-driven asthma

Eline HaspeslaghMary van HeldenKim DeswarteSofie De PrijckJustine Van MoorleghemLouis BoonHamida HammadEric VivierBart Lambrecht

A1 Journal Article in EMBO MOLECULAR MEDICINE

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

Srinath GovindarajanDjoere GaublommeRenée Van der CruyssenEveline VerheugenSofie Van GassenYvan SaeysSimon TavernierTakao IwawakiYehudi BlochSavvas SavvidesBart LambrechtSophie JanssensDirk ElewautMichael Drennan

A1 Journal Article in NATURE COMMUNICATIONS

TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma

Heleen VromanIngrid M BergenJennifer AC van HulstMenno van NimwegenDenise van UdenMartijn SchuijsSaravanan Y PillaiGeert van LooHamida HammadBart LambrechtRudi W HendriksMirjam Kool

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The emerging role of ADAM metalloproteinases in immunity

Bart LambrechtMatthias VanderkerkenHamida Hammad

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

The generation and use of allergen-specific TCR transgenic animals

Manon VanheerswynghelsWendy ToussaintMartijn SchuijsLeen VanhoutteNigel KilleenHamida HammadBart Lambrecht

Bookchapter in Type 2 immunity : methods and protocols

The hygiene hypothesis : immunological mechanisms of airway tolerance

Eline HaspeslaghInes HeyndrickxHamida HammadBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

Charlotte ScottWouter T'JonckLiesbet MartensHelena TodorovDorine SichienBieke SoenJohnny BonnardelSofie De PrijckNiels VandammeRobrecht CannoodtWouter SaelensBavo VannesteWendy ToussaintPieter De BleserNozomi TakahashiPeter VandenabeeleSandrine HenriClare PridansDavid A HumeBart LambrechtPatrick De BaetselierSimon WF MillingJo A Van GinderachterBernard MalissenGeert BerxAlain BeschinYvan SaeysMartin Guilliams

A1 Journal Article in IMMUNITY

The unfolded protein response in the immune cell development : putting the caretaker in the driving seat

Simon TavernierBart LambrechtSophie Janssens

A1 Journal Article in CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model

Sanne D'hondtBrecht GuillemynDelfien SyxSofie SymoensRiet De RyckeLeen VanhoutteWendy ToussaintBart LambrechtAnne De PaepeDouglas R KeeneYoshihiro IshikawaHans Peter BächingerSophie JanssensMathieu BertrandFransiska Malfait

A1 Journal Article in MATRIX BIOLOGY

2017

A CARD9 Turkisch founder mutation disrupts NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneLevi HosteDelfien BogaertMélanie MigaudDeborah KonopnickiBart LambrechtRudi BeyaertElfride De BaereAnne PuelJean-Christophe GoffardFilomeen HaerynckJens StaalMelissa Dullaers

A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes

Bénédicte MachielsMickael DourcyXue XiaoJustine JavauxClaire MesnilCatherine SabatelDaniel DesmechtFrançois LallemandPhilippe MartiniveHamida HammadMartin GuilliamsBenjamin DewalsAlain VanderplasschenBart LambrechtFabrice BureauLaurent Gillet

A1 Journal Article in NATURE IMMUNOLOGY

Bacteria isolated from lung modulate asthma susceptibility in mice

Aude RemotDelphyne DescampsMarie-Louise NoordineAbdelhak BoukadiriElliot MathieuVéronique RobertSabine RiffaultBart LambrechtPhilippe LangellaHamida HammadMuriel Thomas

A1 Journal Article in ISME JOURNAL

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneDelfien BogaertLevi HosteMélanie MigaudJean-Christophe GoffardDeborah KonopnickiBart LambrechtRudi BeyaertElfride De BaereAnne PuelFilomeen HaerynckJens StaalMelissa Dullaers

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneLevi HosteDelfien BogaertMélanie MigaudJean-Christophe GoffardDeborah KonopnickiBart LambrechtRudi BeyaertElfride De BaereAnne PuelFilomeen HaerynckJens StaalMelissa Dullaers

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneDelfien BogaertLevi HosteMélanie MigaudJean-Christophe GoffardDeborah KonopnickiBart LambrechtRudi BeyaertElfride De BaereAnne PuelFilomeen HaerynckJens StaalMelissa Dullaers

Cardiac dendritic cell subsets activate autoreactive T cells in the healthy and diseased heart

Katrien Van Der BorghtBart LambrechtThierry Gillebert

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity

Margherita CocciaCatherine CollignonCaroline HervéAurélie ChalonIain WelsbySophie DetienneMary van HeldenSheetij DuttaChristopher J GenitoNorman C WatersKatrijn Van DeunAge K SmildeRobert A van den BergDavid FrancoPatricia BourguignonSandra MorelNathalie GarçonBart LambrechtStanislas GorielyRobbert van der MostArnaud M Didierlaurent

A1 Journal Article in NPJ VACCINES

Computational analysis of multimorbidity between asthma, eczema and rhinitis

Daniel AguilarMariona PinartGerard H KoppelmanYvan SaeysMartijn C NawijnDirkje S PostmaMübeccel AkdisCharles AuffrayStéphane BallereauMarta BenetJudith García-AymerichJuan Ramon GonzálezStefano GuerraThomas KeilManolis KogevinasBart LambrechtNathanael LemonnierErik MelenJordi SunyerRudolf ValentaSergi ValverdeMagnus WickmanJean BousquetBaldo OlivaJosep M Antó

A1 Journal Article in PLOS ONE

Dendritic cells under stress : on the role of the unfolded protein response and hypoxia signaling

Simon TavernierSophie JanssensBart Lambrecht

Development of conventional dendritic cells : from common bone marrow progenitors to multiple subsets in peripheral tissues

Dorine SichienBart LambrechtMartin GuilliamsCharlotte Scott

A1 Journal Article in MUCOSAL IMMUNOLOGY

Differential requirement for IRF8 in the development and function of monocytes and dendritic cells

Dorine SichienBart LambrechtMartin Guilliams

Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes

Delfien BogaertMelissa DullaersHye Sun KuehnBart LeroyJulie E NiemelaHans De WildeSarah De SchryverMarieke De BruyneFrauke CoppietersBart LambrechtFrans De BaetsSergio D RosenzweigElfride De BaereFilomeen Haerynck

A1 Journal Article in SCIENTIFIC REPORTS

Effects of domestic chemical stressors on expression of allergen genes in the European house dust mite

JC Vidal-QuistF OrtegoBart LambrechtP CastañeraP Hernández-Crespo

A1 Journal Article in MEDICAL AND VETERINARY ENTOMOLOGY

Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells

Julie DeckersDorine SichienMaud PlantingaJustine Van MoorleghemManon VanheerswynghelsEsther HosteBernard MalissenDavid DombrowiczMartin GuilliamsKarolien De BosscherBart LambrechtHamida Hammad

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain

Lana VandersarrenCedric BosteelsManon VanheerswynghelsJames J MoonAndrew J EastonGert Van IsterdaelSophie JanssensBart LambrechtMary van Helden

A1 Journal Article in SCIENTIFIC REPORTS

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

Sophie Van WeldenMartine De VosBen WielockxSimon TavernierMelissa DullaersSara NeytBenedicte DescampsLindsey DevisscherSarah DevrieseLien Van den BosscheTom HolvoetAnn BaeyensCarmen CorrealeSilvia D'AlessioChristian VanhoveFilip De VosBruno VerhasseltGeorg BreierBart LambrechtSophie JanssensPeter CarmelietSilvio DaneseDirk ElewautDebby LaukensPieter Hindryckx

A1 Journal Article in JOURNAL OF PATHOLOGY

House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting

Melissa DullaersMartijn SchuijsMonique WillartKaat FierensJustine Van MoorleghemHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-21 is increased in nasal polyposis and after stimulation with Staphylococcus aureus enterotoxin B

Lien CalusLara DeryckeMelissa DullaersThibaut Van ZeleNatalie De RuyckClaudina Perez NovoGabriële HoltappelsGeert De VosBart LambrechtClaus BachertPhilippe Gevaert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

Stefaan De KokerLien Van HoeckeAns De BeuckelaerKenny RooseKim DeswarteMonique WillartPieter BogaertThomas NaessensBruno De GeestXavier SaelensBart LambrechtJohan Grooten

A1 Journal Article in SCIENTIFIC REPORTS

Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin

Julie DeckersKarolien De BosscherBart LambrechtHamida Hammad

A1 Journal Article in IMMUNOLOGICAL REVIEWS

Location, function, and ontogeny of pulmonary macrophages during the steady state

Natalio GarbiBart Lambrecht

A1 Journal Article in PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanisms of the Development of Allergy (MeDALL) : introducing novel concepts in allergy phenotypes

Josep M AntoJean BousquetMubeccel AkdisCharles AuffrayThomas KeilIsabelle MomasDirkje S PostmaRudolf ValentaMagnus WickmanAnne Cambon-ThomsenTari HaahtelaBart LambrechtKarin C Lodrup CarlsenGerard H KoppelmanJordi SunyerTorsten ZuberbierIsabelle Annesi-MaesanoAlbert ArnoCarsten Bindslev-JensenGiuseppe De CarloFrancesco ForastiereJoachim HeinrichMarek L KowalskiDieter MaierErik MelénHenriette A SmitMarie StandlJohn WrightAnna AsarnojMarta BenetNatalia BallardiniJudith Garcia-AymerichUlrike GehringStefano GuerraCynthia HohmannInger KullChristian LupinekMariona PinartIngebjorg SkrindoMarit WestmanDelphine SmaggheCezmi AkdisNiklas AnderssonClaus BachertStephane BallereauFerran BallesterXavier BasaganaAnna BedbrookAnna BergstromAndrea von BergBert BrunekreefEmilie BurteKai-Hakon CarlsenLeda ChatziJonathan M CoquetMirela CurinPascal DemolyEsben EllerMaria Pia FantiniLeena von HertzenVergard HovlandBenedicte JacqueminJocelyne JustTheresa KellerRenata KissManolis KogevinasSibylle KoletzkoSusanne LauIrina LehmannNicolas LemonnierMika MäkeläJordi MestresPeter MowinckelRachel NadifMartijn C NawijnJohan PelletIsabelle PinDaniela PortaFanny RancièreEmmanuelle Rial-SebbagYvan SaeysMartijn J SchuijsValerie SirouxChristina G TischerMathies TorrentRaphaelle VarrasoKalus WenzelCheng-Jian Xu

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mitochondrial priming by CD28

Ramon I Klein GeltinkDavid O'SullivanMauro CorradoAnna BremserMichael D BuckJoerg M BuescherElke FiratXuekai ZhuGabriele NiedermannGeorge CaputaBeth KellyUrsula WarthorstAnne Rensing-EhlRyan L KyleLana VandersarrenJonathan D CurtisAnnette E PattersonSimon LawlessKatarzyna GrzesJing QiuDavid E SaninOliver KretzTobias B HuberSophie JanssensBart LambrechtAngelika S RamboldEdward J PearceErika L Pearce

A1 Journal Article in CELL

Murine models of allergic asthma

Eline HaspeslaghNincy DebeufHamida HammadBart Lambrecht

Bookchapter in Inflammation : methods and protocols

Myeloid cells in asthma

Bart LambrechtEmma PerssonHamida Hammad

A1 Journal Article in MICROBIOLOGY SPECTRUM

Myocardial infarction primes autoreactive T cells through activation of dendritic cells

Katrien Van Der BorghtCharlotte ScottVeronika NindlAnn BouchéLiesbet MartensDorine SichienJustine Van MoorleghemManon VanheerswynghelsSofie De PrijckYvan SaeysBurkhard LudewigThierry GillebertMartin GuilliamsPeter CarmelietBart Lambrecht

A1 Journal Article in CELL REPORTS

Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages

Simon TavernierNele VanlangenakkerJessica VettersPeter CarmelietSophie JanssensBart Lambrecht

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

PPAR-γ promotes type 2 immune responses in allergy and nematode infection

Ting ChenChristopher A TibbittXiaogang FengJulian M StarkLeona RohrbeckLisa RauschSaikiran K SedimbiMikael CI KarlssonBart LambrechtGunilla B Karlsson HedestamRudi W HendriksBenedict J ChambersSusanne NylénJonathan M Coquet

A1 Journal Article in SCIENCE IMMUNOLOGY

Probiotics-impregnated bedding covers for house dust mite allergic rhinitis : a pilot randomized clinical trial

Margot BeringsAnton JultHanne VermeulenNatalie De RuyckLara DeryckeH UcarP GhekiereR TemmermanJ EllisClaus BachertBart LambrechtMelissa DullaersPhilippe Gevaert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Probiotics-impregnated bedding covers in house dust mite allergic rhinitis patients : a double-blind, randomised, placebo-controlled, crossover clinical trial

Margot BeringsAnton JultHans VermeulenNatalie De RuyckLara DeryckeH. UcarP. GhekiereR. TemmermanJ. EllisClaus BachertBart LambrechtMelissa DullaersPhilippe Gevaert

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon TavernierFabiola OsorioLana VandersarrenJessica VettersNele VanlangenakkerGert Van IsterdaelKarl VergoteRiet De RyckeEef ParthoensLianne van de LaarTakao IwawakiJuan R Del ValleChih-Chi Andrew HuBart LambrechtSophie Janssens

A1 Journal Article in NATURE CELL BIOLOGY

Reliable mite-specific IgE testing in nasal secretions by means of allergen microarray

Margot BeringsStefania ArasiNatalie De RuyckSerena PernaYvonne ReschChristian LupinekKuan-Wei ChenSusanne VrtalaGiovanni Battista PajnoClaus BachertBart LambrechtMelissa DullaersRudolf ValentaPaolo Maria MatricardiPhilippe Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

Kenneth VerstraeteFrank PeelmanHarald BraunJuan LopezDries Van RompaeyAnn DansercoerIsabel VandenbergheKris PauwelsJan TavernierBart LambrechtHamida HammadHans De WinterRudi BeyaertGuy LippensSavvas Savvides

A1 Journal Article in NATURE COMMUNICATIONS

Suppression of allergen-induced basophil activation upon treatment with subcutaneous house dust mite immunotherapy: a prospective study

Margot BeringsNatalie De RuyckLara DeryckeGabriële HoltappelsClaus BachertBart LambrechtMelissa DullaersPhilippe Gevaert

TGF-β gives an air of exclusivity to alveolar macrophages

Editorial material

The immunology of the allergy epidemic and the hygiene hypothesis

Bart LambrechtHamida Hammad

A1 Journal Article in NATURE IMMUNOLOGY

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa KerreAndrea CeruttiKarim VermaelenFilomeen HaerynckMelissa Dullaers

A1 Journal Article in HAEMATOLOGICA

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa KerreAndrea CeruttiKarim VermaelenFilomeen HaerynckMelissa Dullaers

The pathogenesis of house dust mite-driven asthma : from barn to bedside

Martijn SchuijsHamida HammadBart Lambrecht

The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome

Lotte PyfferoenElisabeth BrabantsCeline EveraertNancy De CabooterKelly HeynsKim DeswarteManon VanheerswynghelsSofie De PrijckGlenn WaegemansMelissa DullaersHamida HammadOlivier De WeverPieter MestdaghJo VandesompeleBart LambrechtKarim Vermaelen

A1 Journal Article in ONCOIMMUNOLOGY

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10

Hamida HammadMatthias VanderkerkenPhilippe PouliotKim DeswarteWendy ToussaintKarl VergoteLana VandersarrenSophie JanssensIoanna RamouSavvas SavvidesJody HaighRudi HendriksManfred KopfKatleen CraessaertsBart de StrooperJohn F KearneyDaniel H ConradBart Lambrecht

A1 Journal Article in NATURE IMMUNOLOGY

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

Diane LefaudeuxBertrand De MeulderMatthew J LozaNancy PefferAnthony RoweFrederic BaribaudAruna T BansalRene LutterAna R SousaJulie CorfieldIoannis PandisPer S BakkeMassimo CarusoPascal ChanezSven-Erik DahlenLouise J FlemingStephen J FowlerIldiko HorvathNorbert KrugPaolo MontuschiMarek SanakThomas SandstromDominic E ShawFlorian SingerPeter J SterkGraham RobertsIan M AdcockRatko DjukanovicCharles AuffrayKian Fan ChungU-BIOPRED Study GroupBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2016

A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes

N AghaeepourP ChattopadhyayM ChikinaTom DhaeneSofie Van GassenM KursaBart LambrechtM MalekGJ McLachlanY QianP QiuYvan SaeysR StantonD TongCeline VensS WalkowiakK WangG FinakR GottardoT MosmannGP NolanRH ScheuermannRR Brinkman

A1 Journal Article in CYTOMETRY PART A

A generic polymer-protein ligation strategy for vaccine delivery

Lien LybaertNane VanparijsKaat FierensMartijn SchuijsLutz NuhnBart LambrechtBruno De Geest

A1 Journal Article in BIOMACROMOLECULES

A new aDENNDum to genetics of childhood asthma

Marie GodarBart Lambrecht

Editorial material

A20 deficiency in lung epithelial cells protects against influenza A virus infection

Jonathan MaelfaitKenny RooseLars VereeckeConor Mc GuireMozes SzeMartijn SchuijsMonique WillartLorena IbanezHamida HammadBart LambrechtRudi BeyaertXavier SaelensGeert van Loo

A1 Journal Article in PLOS PATHOGENS

ARIA 2016 : care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

J BousquetPW HellingsI AgacheA BedbrookClaus BachertKC BergmannM BewickC Bindslev-JensenS Bosnic-AnticevitchC BuccaDP CaimmiPAM CamargosGW CanonicaT CasaleNH ChavannesAA CruzG De CarloR DahlP DemolyP DevillierJ FonsecaWJ FokkensNA GuldemondT HaahtelaM IllarioJ JustT KeilL KlimekP KunaD Larenas-LinnemannM Morais-AlmeidaJ MullolR MurrayR NaclerioRE O’HehirNG PapadopoulosR PawankarP PotterD RyanB SamolinskiHJ SchunemannA SheikhFER SimonsC StellatoA Todo-BomPV TomazicA ValiulisE ValovirtaMT VenturaM WickmanI YoungA YorganciogluT ZuberbierW AbererCA AkdisM AkdisI Annesi-MaesanoJ AnkriIJ AnsoteguiJM AntoS ArnavielheA AsarnojH ArshadF AvolioI BaiardiniC BarbaraM BarbagalloED BatemanB BeghéEH BelKS BennoorM BensonAZ BiałoszewskiT BieberL BjermerH BlainF BlasiAL BonerM BoniniS BoniniI BosseJ BouchardLP BouletR BourretPJ BousquetF BraidoAH BriggsCE BrightlingJ BrozekR BuhlC BunuE BurteA BushF Caballero-FonsecaMA CalderonT CamuzatV CardonaP Carreiro-MartinsAM CarriazoKH CarlsenW CarrAM Cepeda SarabiaM CesariL ChatziR ChironT ChivatoE ChkhartishviliAG ChuchalinKF ChungG CiprandiJ Correia de SousaL CoxG CrooksA CustovicSE DahlenU DarsowT DedeuD DeleanuJA DenburgG De VriesA DidierAT Dinh-XuanD DokicH DouaguiG DrayR DubakieneSR DurhamG Du ToitMS DykewiczP EklundY El-GamalE EllersR EmuzyteJ FarrellA Fink WagnerA FiocchiM FletcherF ForastiereM GagaA GamkrelidzeB GemicioğluJE GeredaR Gerth van WickS González DiazI GrisleL GrouseZ GutterMA GuzmánB Hellquist-DahlJ HeinrichF HorakJO’B HourihaneM HumbertM HylandG IaccarinoEJ JaresC JeandelSL JohnstonGuy JoosO JonquetKS JungM JutelI KaidashevM KhaitovO KalayciAF KalyoncuP KardasPK KeithM KerkhofHAM KerstjensN KhaltaevM KogevinasV KolekGH KoppelmanML KowalskiM KuitunenI KullV KvedarieneBart LambrechtS LauD LauneLTT LeP LiebermanB LipworthJ LiKC Lodrup CarlsenR LouisC LupinekW MacNeeY MagarA MagnanB MahboubD MaierI MajerJ MalvaP ManningE De Manuel KeenoyGD MarshallMR MasjediE Mathieu-DupasM MaurerS Mavale-ManuelE MelénE Melo-GomesEO MeltzerJ MercierH MerkN MiculinicF MihaltanB MilenkovicJ Millot-KeurinckY MohammadI MomasR MösgesA MuraroL Namazova-BaranovaR NadifH NeffenK NekamA NietoB NiggemannL Nogueira-SilvaM NoguesTD NyembueK OhtaY OkamotoK OkuboM Olive-EliasS OuedraogoP PaggiaroI Pali-SchöllS PalkonenP PanznerA PapiHS ParkG PassalacquaS PedersenAM PereiraO PfaarR PicardB PigeariasI PinD PlavecW PohlTA PopovF PortejoieD PostmaLK PoulsenD PriceKF RabeF RaciborskiG RobertsC Robalo-CordeiroF RodenasL Rodriguez-MañasC RollandM Roman RodriguezA RomanoJ Rosado-PintoN RosarioM RottemM Sanchez-BorgesJ Sastre-DominguezGK ScaddingN ScichiloneP Schmid-GrendelmeierE SerranoM ShieldsV SirouxJC SisulI SkrindoHA SmitD SoléT SooronbaevO SprangerR StelmachPJ SterkT StrandbergJ SunyerC ThijsM TriggianiR ValentaA ValeroM van EerdE van GanseM van HagueO VandenplasLL VaronaB VellasG VezzaniT VazankariG ViegiT VontetsianosM WagenmannS WalkerDY WangU WahnT WerfelB WhalleyDM WilliamsS WilliamsN WilsonJ WrightBP YawnPK YiallourosOM YusufA ZaidiHJ ZarME ZernottiL ZhangN ZhongM Zidarn

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Charlotte ScottFang ZhengPatrick De BaetselierLiesbet MartensYvan SaeysSofie De PrijckSaskia LippensChloé AbelsSteve SchoonoogheGeert RaesNick DevoogdtBart LambrechtAlain BeschinMartin Guilliams

A1 Journal Article in NATURE COMMUNICATIONS

CVID, isolated IgG deficiency and isolated IgG subclass deficiency : clinical features and B cell maturation of the Ghent cohort

Delfien BogaertVeronique De BackerTessa KerreMaria Bordon Cueto De BraemBart LambrechtKarim VermaelenFrans De BaetsElfride De BaereMelissa DullaersFilomeen Haerynck

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice

Muriel SmetLien Van HoeckeAns De BeuckelaerSeppe Vander BekenThomas NaessensKarl VergoteMonique WillartBart LambrechtJan-Ake GustafssonKnut R SteffensenJohan Grooten

A2 Journal Article in IMMUNITY INFLAMMATION AND DISEASE

Chronic and invasive fungal infections in a family with CARD9 deficiency

Ana Alves de MedeirosEVELYNE LODEWICKDelfien BogaertFilomeen HaerynckSabine Van daeleBart LambrechtSarah BosmaLaure VanderdoncktOlivier LortholaryMélanie MigaudJean-Laurent CasanovaAnne PuelFanny LanternierJo LambertLieve BrochezMelissa Dullaers

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Computational flow cytometry: helping to make sense of high-dimensional immunology data

Yvan SaeysSofie Van GassenBart Lambrecht

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

Conventional dendritic cells : identification, subsets, development, and functions

Charlotte ScottBart Lambrecht

Bookchapter in Encyclopedia of immunobiology, vol. 3 : activation of the immune system

Dendritic cells and type 2 inflammation

Bart LambrechtMary van HeldenHamida Hammad

Bookchapter in The Th2 type immune response in health and disease

Double-negative T resident memory cells of the lung react to influenza virus infection via CD11chi dendritic cells

Katrijn NeytCH GeurtsvanKesselBart Lambrecht

A1 Journal Article in MUCOSAL IMMUNOLOGY

Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy

Marie GodarVirginia MorelloAva SadiAnna HultbergNatalie De JongeCristina BasilicoValérie HanssensMichael SaundersBart LambrechtMohamed El KhattabiHans de HaardPaolo MichieliChristophe Blanchetot

A1 Journal Article in SCIENTIFIC REPORTS

Early IL-1 signaling promotes iBALT induction after influenza virus infection

Katrijn NeytCorine H GeurtsvanKesselKim DeswarteHamida HammadBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

FloReMi : flow density survival regression using minimal feature redundancy

Sofie Van GassenCeline VensTom DhaeneBart LambrechtYvan Saeys

A1 Journal Article in CYTOMETRY PART A

GATA1-deficient dendritic cells display impaired CCL21-dependent migration toward lymph nodes due to reduced levels of polysialic acid

Maaike R ScheenstraIris M De CuyperFilipe Branco MadeiraPieter De BleserMirjam KoolMarjolein MeindersMark HoogenboezemErik MuMonika C WolkersFiamma SalernoBenjamin NotaYvan SaeysSjoerd KlarenbeekWilfred FJ van IJckenHamida HammadSjaak PhilipsenTimo K van den BergTaco W KuijpersBart LambrechtLaura Gutierrez

A1 Journal Article in JOURNAL OF IMMUNOLOGY

GM-CSF treatment prevents respiratory syncytial virus– induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation

Thomas NaessensBert SchepensMuriel SmetCharlotte PollardLien Van HoeckeAns De BeuckelaerMonique WillartBart LambrechtStefaan De KokerXavier SaelensJohan Grooten

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genes associated with common variable immunodeficiency: one diagnosis to rule them all?

Delfien BogaertMelissa DullaersBart LambrechtKarim VermaelenElfride De BaereFilomeen Haerynck

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively

Dorine SichienCharlotte ScottLiesbet MartensMatthias VanderkerkenSofie Van GassenMaud PlantingaThorsten JoerisSofie De PrijckLeen VanhoutteManon VanheerswynghelsGert Van IsterdaelWendy ToussaintFilipe Branco MadeiraKarl VergoteWilliam W AgaceBjörn E ClausenHamida HammadMarc DalodYvan SaeysBart LambrechtMartin Guilliams

A1 Journal Article in IMMUNITY

IRF8 transcription-factor-dependent classical dendritic cells are essential for intestinal T cell homeostasis

Katarzyna M LudaThorsten JoerisEmma PerssonAymeric RivollierMimoza DemiriKatarzyna M SitnikLieneke PoolJacob B HolmFelipe Melo-GonzalezLisa RichterBart LambrechtKarsten KristiansenMark A TravisMarcus Svensson-FrejKnut KotarskyWilliam W Agace

A1 Journal Article in IMMUNITY

JAK2 deficiency as a novel cause of impaired Th17 immunity

FILOMEEN HAERYNCKDelfien BogaertElfride De BaereKristof Van SchilFrauke CoppietersMarieke De BruyneMargot HagendorensTessa KerreFrans De BaetsMaria Bordon Cueto De BraemKarim VermaelenJan TavernierBart LambrechtSarah GerloMelissa Dullaers

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Jean BousquetHolger J SchünemannPeter W HellingsSylvie ArnavielheClaus BachertAnna BedbrookKarl-Christian BergmannSinthia Bosnic-AnticevichJan BrozekMoises CalderonG Walter CanonicaThomas B CasaleNiels H ChavannesLinda CoxHenry ChrystynAlvaro A CruzRonald DahlGiuseppe De CarloPascal DemolyPhillipe DevillierGérard DrayMonica FletcherWytske J FokkensJoao FonsecaSandra N Gonzalez-DiazLawrence GrouseThomas KeilPiotr KunaDésirée Larenas-LinnemannKarin C Lodrup CarlsenEli O MeltzerJaoquim MullolAntonella MuraroRobert N NaclerioSusanna PalkonenNikolaos G PapadopoulosGiovanni PassalacquaDavid PriceDermot RyanBoleslaw SamolinskiGlenis K ScaddingAziz SheikhFrançois SpertiniArunas ValiulisErkka ValovirtaSamantha WalkerMagnus WickmanArzu YorganciogluTari HaahtelaTorsten Zuberbieron behalf of the MASK study groupBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophage precursors PLASTed INto alveolar space

Martin GuilliamsBart Lambrecht

Editorial material

Mouse models of asthma

Nincy DebeufEline HaspeslaghMary van HeldenHamida HammadBart Lambrecht

Bookchapter in Current protocols in mouse biology

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNF AIP3/A20

Michael DrennanSrinath GovindarajanEveline VerheugenJonathan CoquetJens StaalConor Mc GuireTom TaghonGeorges LeclercqRudi BeyaertGeert van LooBart LambrechtDirk Elewaut

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase

Assem ZhakupovaNincy DebeufMichiel KrolsWendy ToussaintLeen VanhoutteIrina AlecuZoltán KutalikPeter VollenweiderDaniela ErnstArnold von EckardsteinBart LambrechtSophie JanssensThorsten Hornemann

A1 Journal Article in FASEB JOURNAL

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; project no: 261357; 2010-2015

J BousquetJM AntoM AkdisC AuffrayT KeilI MomasDS PostmaR ValentaM WickmanA Cambon-ThomsenT HaahtelaBart LambrechtKCL CarlsenGH KoppelmanJ SunyerT ZuberbierI Annesi-MaesanoA ArnoC Bindslev-JensenG De CarloF ForastiereJ HeinrichML KowalskiD MaierE MelenS PalkonenHA SmitM StandlJ WrightA AsarnojM BenetN BallardiniJ Garcia-AymerichU GehringS GuerraC HohmanI KullC LupinekM PinartI SkrindoM WestmanD SmaggheC AkdisR AlbangV AnastasovaN AndersonClaus BachertS BallereauF BallesterX BasaganaA BedbrookA BergstromA von BergB BrunekreefE BurteKH CarlsenL ChatziJonathan CoquetM CurinP DemolyE EllerMP FantiniB GerhardHamida HammadL von HertzenV HovlandB JacqueminJ JustT KellerM KerkhofR KissM KogevinasS KoletzkoS LauI LehmannN LemonnierR McEachanM MakelaJ MestresE MininaP MowinckelR NadifM NawijnS OddieJ PelletI PinD PortaF RanciereA Rial-SebbagYvan SaeysMartijn SchuijsV SirouxCG TischerM TorrentR VarrasoJ De VochtK WengerS WieserC Xu

A1 Journal Article in ALLERGY

Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung

Ismé De KleerMirjam KoolMarjolein JW de BruijnMonique WillartJustine Van MoorleghemMartijn SchuijsMaud PlantingaRudi BeyaertEmily HamsPadraic G FallonHamida HammadRudi W HendriksBart Lambrecht

A1 Journal Article in IMMUNITY

Pulmonary immune responses against influenza A virus infection

Katrijn NeytBart LambrechtMartin GuilliamsCorine Geurts van Kessel

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

J BousquetJ FarrellG CrooksP HellingsEH BelM BewickNH ChavannesJ Correia de SousaAA CruzT HaahtelaGuy JoosN KhaltaevJ MalvaA MuraroM NoguesS PalkonenS PedersenC Robalo-CordeiroB SamolinskiT StrandbergA ValiulisA YorganciogluT ZuberbierA BedbrookW AbererM AdachiA AgustiCA AkdisM AkdisJ AnkriA AlonsoI Annesi-MaesanoIJ AnsoteguiJM AntoS ArnavielheH ArshadC BaiI BaiardiniClaus BachertAK BaigenzhinC BarbaraED BatemanB BeghéA Ben KhederKS BennoorM BensonKC BergmannT BieberC Bindslev-JensenL BjermerH BlainF BlasiAL BonerM BoniniS BoniniS Bosnic-AnticevitchLP BouletR BourretPJ BousquetF BraidoAH BriggsCE BrightlingJ BrozekR BuhlPG BurneyA BushF Caballero-FonsecaD CaimmiMA CalderonPM CalverleyPAM CamargosGW CanonicaT CamuzatKH CarlsenW CarrA CarriazoT CasaleAM Cepeda SarabiaL ChatziYZ ChenR ChironE ChkhartishviliAG ChuchalinKF ChungG CiprandiI CiruleL CoxDJ CostaA CustovicR DahlSE DahlenU DarsowG De CarloF De BlayT DedeuD DeleanuE De Manuel KeenoyP DemolyJA DenburgP DevillierA DidierAT Dinh-XuanR DjukanovicD DokicH DouaguiG DrayR DubakieneSR DurhamMS DykewiczY El-GamalR EmuzyteLM FabbriM FletcherA FiocchiA Fink WagnerJ FonsecaWJ FokkensF ForastiereP FrithM GagaA GamkrelidzeJ GarcesJ Garcia-AymerichB GemicioğluJE GeredaS González DiazM GotuaI GrisleL GrouseZ GutterMA GuzmánLG HeaneyB Hellquist-DahlD HendersonA HendryJ HeinrichD HeveF HorakJO’B HourihaneP HowarthM HumbertME HylandM IllarioJC IvancevichJR JardimEJ JaresC JeandelC JenkinsSL JohnstonO JonquetK JulgeKS JungJ JustI KaidashevMR KhaitovO KalayciAF KalyoncuT KeilPK KeithL KlimekB Koffi N’GoranV KolekGH KoppelmanML KowalskiI KullP KunaV KvedarieneBart LambrechtS LauD Larenas-LinnemannD LauneLTT LeP LiebermanB LipworthJ LiK Lodrup CarlsenR LouisW MacNeeY MagardA MagnanB MahboubA MairI MajerMJ MakelaP ManningS MaraGD MarshallMR MasjediP MatignonM MaurerS Mavale-ManuelE MelénE Melo-GomesEO MeltzerA Menzies-GowH MerkJP MichelN MiculinicF MihaltanB MilenkovicGMY MohammadM MolimardI MomasA Montilla-SantanaM Morais-AlmeidaM MorganR MösgesJ MullolS NaftiL Namazova-BaranovaR NaclerioA NeouH NeffenK NekamB NiggemannG NinotTD NyembueRE O’HehirK OhtaY OkamotoK OkuboS OuedraogoP PaggiaroI Pali-SchöllP PanznerN PapadopoulosA PapiHS ParkG PassalacquaI PavordR PawankarR PengellyO PfaarR PicardB PigeariasI PinD PlavecD PoethigW PohlTA PopovF PortejoieP PotterD PostmaD PriceKF RabeF RaciborskiF Radier PontalS Repka-RamirezS ReitamoS RennardF RodenasJ RobertsJ RocaL Rodriguez MañasC RollandM Roman RodriguezA RomanoJ Rosado-PintoN RosarioL RosenwasserM RottemD RyanM Sanchez-BorgesGK ScaddingHJ SchunemannE SerranoP Schmid-GrendelmeierH SchulzA SheikhM ShieldsN SiafakasY SibilleT SimilowskiFER SimonsJC SisulI SkrindoHA SmitD SoléT SooronbaevO SprangerR StelmachPJ SterkJ SunyerC ThijsT ToA Todo-BomM TriggianiR ValentaAL ValeroE ValiaE ValovirtaE Van GanseM van HageO VandenplasT VasankariB VellasJ VestboG VezzaniP VichyanondG ViegiC VogelmeierT VontetsianosM WagenmannB WallaertS WalkerDY WangU WahnM WickmanDM WilliamsS WilliamsJ WrightBP YawnPK YiallourosOM YusufA ZaidiHJ ZarME ZernottiL ZhangN ZhongM ZidarnJ Mercier

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery

Hui LiKaat FierensZhiyue ZhangNane VanparijsMartijn SchuijsKatleen Van SteendamNatalia Feiner GraciaRiet De RyckeThomas De BeerAns De BeuckelaerStefaan De KokerDieter DeforceLorenzo AlbertazziJohan GrootenBart LambrechtBruno De Geest

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology

Delfien BogaertPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemTessa KerreBart LambrechtAndrea CeruttiKarim VermaelenElfride De BaereFilomeen HaerynckMelissa Dullaers

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Charlotte ScottBieke SoenLiesbet MartensNicolas SkrypekWouter SaelensJoachim TaminauGillian BlanckeGert Van IsterdaelDanny HuylebroeckJody HaighYvan SaeysMartin GuilliamsBart LambrechtGeert Berx

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

Martin GuilliamsCharles-Antoine DutertreCharlotte ScottNaomi McGovernDorine SichienSvetoslav ChakarovSofie Van GassenJinmiao ChenMichael PoidingerSofie De PrijckSimon TavernierIvy LowSergio Erdal IracCitra Nurfarah MattarHermi Rizal SumatohGillian Hui Ling LowTam John Kit ChungDedrick Kok Hong ChanKer Kan TanTony Lim Kiat HonEven FossumBjarne BogenMahesh ChoolaniJerry Kok Yen ChanAnis LarbiHervé LucheSandrine HenriYvan SaeysEvan William NewellBart LambrechtBernard MalissenFlorent Ginhoux

A1 Journal Article in IMMUNITY

Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures

Lisa ThyrionRobrecht RaedtJeanelle PortelliPieter Van LooWytse WadmanGriet GlorieuxBart LambrechtSophie JanssensKristl VonckPaul Boon

A1 Journal Article in EXPERIMENTAL NEUROLOGY

Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

Matthew J. LozaRatko DjukanovicKian Fan ChungDaniel HorowitzKeying MaPatrick BraniganElliot S. BarnathanVedrana S. SusulicPhilip E. SilkoffPeter J. SterkFrederic Baribaudfor the U-BIOPRED study groupBart Lambrecht

A1 Journal Article in RESPIRATORY RESEARCH

Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages

Lianne van de LaarWouter SaelensSofie De PrijckLiesbet MartensCharlotte ScottGert Van IsterdaelEik HoffmannRudi BeyaertYvan SaeysBart LambrechtMartin Guilliams

A1 Journal Article in IMMUNITY

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

Lutz NuhnNane VanparijsAns De BeuckelaerLien LybaertGlenn VerstraeteKim DeswarteStefan LienenklausNikunj M ShuklaAlex CD SalyerBart LambrechtJohan GrootenSunil A DavidStefaan De KokerBruno De Geest

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Glucan exacerbates allergic airway responses to house dust mite allergen

Sabelo HadebeFrank KirsteinKaat FierensPierre RedelinghuysGraeme I MurrayDavid L WilliamsBart LambrechtFrank BrombacherGordon D Brown

A1 Journal Article in RESPIRATORY RESEARCH

2015

A novel STAT1 mutation in a patient with pneumocystis jiroveci and chronic mucocutaneous candidiasis

Delfien BogaertMelissa DullaersJens StaalSarah GerloElien VandermarliereVeronique De BackerMaria Bordon Cueto De BraemKathleen De WaeleIsabelle MeytsLeen MoensXavier BossuytFrans De BaetsBart LambrechtKarim VermaelenFilomeen Haerynck

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? : the MeDALL hypothesis

J BousquetJM AntoM WickmanT KeilR ValentaT HaahtelaK Lodrup CarlsenM van HageC AkdisClaus BachertM AkdisC AuffrayI Annesi-MaesanoC Bindslev-JensenA Cambon-ThomsenKH CarlsenL ChatziF ForastiereJ Garcia-AymerichU GehrigS GuerraJ HeinrichGH KoppelmanML KowalskiBart LambrechtC LupinekD MaierE MelénI MomasS PalkonenM PinartD PostmaV SirouxHA SmitJ SunyerJ WrightT ZuberbierSH ArshadR NadifC ThijsN AnderssonA AsarnojN BallardiniS BallereauA BedbrookM BenetA BergstromB BrunekreefE BurteM CalderonG De CarloP DemolyE EllerMP FantiniHamida HammadC HohmanJ JustM KerkhofM KogevinasI KullS LauN LemonnierM MommersM NawijnA NeubauerS OddieJ PelletI PinD PortaYvan SaeysI SkrindoCG TischerM TorrentL von Hertzen

A1 Journal Article in ALLERGY

Barrier epithelial cells and the control of type 2 immunity

Hamida HammadBart Lambrecht

A1 Journal Article in IMMUNITY

CCR2⁺CD103⁻ intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells

Charlotte ScottCC BainPB WrightDorine SichienK KotarskyEmma PerssonK LudaMartin GuilliamsBart LambrechtWW AgaceSWF MillingAM Mowat

A1 Journal Article in MUCOSAL IMMUNOLOGY

Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells

Ruth De BruyneDelfien BogaertNatalie De RuyckBart LambrechtMyriam Van WinckelPhilippe GevaertMelissa Dullaers

A1 Journal Article in CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Does circulating IL-17 identify a subset of patients with idiopathic pulmonary arterial hypertension?: response

Aurélie HautefortBarbara GirerdDavid MontaniSylvia Cohen-KaminskyLaura PriceBart LambrechtMarc HumbertFrédéric Perros

A1 Journal Article in CHEST

Epithelial cell regulation of immune responses in the lung

Bookchapter in Mucosal immunology

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

Martijn SchuijsMonique WillartKarl VergoteDelphine GrasKim DeswarteMarkus J EgeFilipe Branco MadeiraRudi BeyaertGeert van LooFranz BracherErika von MutiusPascal ChanezBart LambrechtHamida Hammad

A1 Journal Article in SCIENCE

FlowSOM: using self-organizing maps for visualization and interpretation of cytometry data

Sofie Van GassenBritt CallebautMary van HeldenBart LambrechtPiet DemeesterTom DhaeneYvan Saeys

A1 Journal Article in CYTOMETRY PART A

Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming

Melanie MatheuShivashankar OthyMilton L GreenbergTobias X DongMartijn SchuijsKim DeswarteHamida HammadBart LambrechtIan ParkerMichael D Cahalan

A1 Journal Article in NATURE COMMUNICATIONS

Immunological characterization of pediatric liver transplant associated food allergy

Ruth De BruynePhilippe GevaertMyriam Van WinckelNatalie De RuyckAurelie MinneDelfien BogaertStephanie Van BiervlietSaskia Vande VeldeFrançoise SmetsEtienne SokalFrédéric GottrandJeremy VanhelstBruno DetryCharles PiletteBart LambrechtMelissa DullaersXavier Rogiers

Impaired survival of regulatory T cells in pulmonary sarcoidosis

Caroline E BroosMenno van NimwegenAlex KleinjanBregje ten BergeFemke MuskensJohannes CCM In't VeenJouke T AnnemaBart LambrechtHenk C HoogstedenRudy W HendriksMirjam KoolBernt van den Blink

A1 Journal Article in RESPIRATORY RESEARCH

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart LambrechtTom TaghonGeorges LeclercqTessa KerreBart Vandekerckhove

A1 Journal Article in HAEMATOLOGICA

Interleukin-21-producing CD4(+) T cells promote type 2 immunity to house dust mites

Jonathan CoquetMartijn SchuijsMark J SmythKim DeswarteRudi BeyaertHarald BraunLouis BoonGunilla B Karlsson HedestamSteven L NuttHamida HammadBart Lambrecht

A1 Journal Article in IMMUNITY

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

J BousquetHJ SchunemannJ FonsecaB SamolinskiClaus BachertGW CanonicaT CasaleAA CruzP DemolyP HellingsA ValiulisM WickmanT ZuberbierS Bosnic-AnticevitchA BedbrookKC BergmannD CaimmiR DahlWJ FokkensI GrisleK Lodrup CarlsenJ MullolA MuraroS PalkonenN PapadopoulosG PassalacquaD RyanE ValovirtaA YorganciogluW AbererI AgacheM AdachiCA AkdisM AkdisI Annesi-MaesanoIJ AnsoteguiJM AntoS ArnavielheH ArshadI BaiardiniAK BaigenzhinC BarbaraED BatemanB BegheEH BelA Ben KhederKS BennoorM BensonM BewickT BieberC Bindslev-JensenL BjermerH BlainAL BonerLP BouletM BoniniS BoniniI BosseR BourretPJ BousquetF BraidoAH BriggsCE BrightlingJ BrozekR BuhlPG BurneyA BushF Caballero-FonsecaMA CalderonPAM CamargosT CamuzatKH CarlsenW CarrAMC SarabiaNH ChavannesL ChatziYZ ChenR ChironE ChkhartishviliAG ChuchalinG CiprandiI CiruleJC de SousaL CoxG CrooksDJ CostaA CustovicSE DahlenU DarsowG De CarloF De BlayT DedeuD DeleanuJA DenburgP DevillierA DidierAT Dinh-XuanD DokicH DouaguiG DrayR DubakieneSR DurhamMS DykewiczY El-GamalR EmuzyteAF WagnerM FletcherA FiocchiF ForastiereA GamkrelidzeB GemiciogluJE GeredaSG DiazM GotuaL GrouseMA GuzmanT HaahtelaB Hellquist-DahlJ HeinrichF HorakJOB HourihaneP HowarthM HumbertME HylandJC IvancevichEJ JaresSL JohnstonGuy JoosO JonquetKS JungJ JustI KaidashevO KalayciAF KalyoncuT KeilPK KeithN KhaltaevL KlimekBK N'GoranV KolekGH KoppelmanML KowalskiI KullP KunaV KvedarieneBart LambrechtS LauD Larenas-LinnemannD LauneLTT LeP LiebermanB LipworthJ LiR LouisY MagardA MagnanB MahboubI MajerMJ MakelaP ManningED KeenoyGD MarshallMR MasjediM MaurerS Mavale-ManuelE MelenE Melo-GomesEO MeltzerH MerkN MiculinicF MihaltanB MilenkovicY MohammadM MolimardI MomasA Montilla-SantanaM Morais-AlmeidaR MosgesL Namazova-BaranovaR NaclerioA NeouH NeffenK NekamB NiggemannTD NyembueRE O'HehirK OhtaY OkamotoK OkuboS OuedraogoP PaggiaroI Pali-SchollS PalmerP PanznerA PapiHS ParkI PavordR PawankarO PfaarR PicardB PigeariasI PinD PlavecW PohlTA PopovF PortejoieD PostmaP PotterD PriceKF RabeF RaciborskiFR PontalS Repka-RamirezC Robalo-CordeiroC RollandJ Rosado-PintoS ReitamoF RodenasM Roman RodriguezA RomanoN RosarioL RosenwasserM RottemM Sanchez-BorgesGK ScaddingE SerranoP Schmid-GrendelmeierA SheikhFER SimonsJC SisulI SkrindoHA SmitD SoleT SooronbaevO SprangerR StelmachT StrandbergJ SunyerC ThijsA Todo-BomM TriggianiR ValentaAL ValeroM van HageO VandenplasG VezzaniP VichyanondG ViegiM WagenmannS WalkerDY WangU WahnDM WilliamsJ WrightBP YawnPK YiallourosOM YusufHJ ZarME ZernottiL ZhangN ZhongM ZidarnJ Mercier

A1 Journal Article in ALLERGY

Microbial ligand costimulation drives neutrophilic steroid-refractory asthma

Sabelo HadebeFrank KirsteinKaat FierensKong ChenRebecca A DrummondSimon VautierSara SajaniemiGraeme MurrayDavid L WilliamsPierre RedelinghuysTodd A ReinhartBeth A Fallert JuneckoJay K KollsBart LambrechtFrank BrombacherGordon D Brown

A1 Journal Article in PLOS ONE

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

Yves-Paul VandewynckelDebby LaukensEliene BogaertsAnnelies ParidaensAnja Van den BusscheXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis LibbrechtRiet De RyckeBart LambrechtAnja GeertsSophie JanssensHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY INTERNATIONAL

Mucosal Immunity in the oral cavity, upper respiratory tract and adjacent areas : an overview

Michael W RussellBart Lambrecht

Bookchapter in Mucosal immunology

Mucosal dendritic cells : origins, subsets and biology

Bart LambrechtAkiko IwasakiBrian L Kelsall

Bookchapter in Mucosal immunology

Mucosal immunology

Mucosal immunology

Nasal immunity, rhinitis, rhinosinustis

Claus BachertOlga KryskoPhilippe GevaertMargot BeringsClaudina Perez NovoKoen Van Crombruggen

Bookchapter in Mucosal immunology

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Lien DejagerKaren DendonckerMelanie EggermontJolien SouffriauFilip Van HauwermeirenMonique WillartElien Van WonterghemThomas NaessensMarlies BallegeerSofie VandevyverHamida HammadBart LambrechtKarolien De BosscherJohan GrootenClaude Libert

A1 Journal Article in MUCOSAL IMMUNOLOGY

Overview : mucosal immunity and disease in the respiratory tract

Bookchapter in Mucosal immunology

Overview : the mucosal immune system

Michael W RussellJiri MesteckyWarren StroberBart LambrechtBrian L. KelsallHilde Cheroutre

Bookchapter in Mucosal immunology

Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster

J Garcia-AymerichM BenetYvan SaeysM PinartX BasagañaHA SmitV SirouxJ JustI MomasF RancièreT KeilC HohmannS LauU WahnJ HeinrichCG TischerMP FantiniJ LenziD PortaGH KoppelmanDS PostmaD BerdelS KoletzkoM KerkhofU GehringM WickmanE MelénJ HallbergC Bindslev-JensenE EllerI KullKC Lødrup CarlsenK-H CarlsenBart LambrechtM KogevinasJ SunyerF KauffmannJ BousquetJM Antó

A1 Journal Article in ALLERGY

Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in paediatric liver transplant patients

Ruth De BruynePhilippe GevaertMyriam Van WinckelNatalie De RuyckAurelie MinneDelfien BogaertStephanie Van BiervlietSaskia Vande VeldeFrancoise SmetsEtienne SokalFréderic GottrandJérémy VanhelstBruno DetryCharles PiletteBart LambrechtMelissa Dullaers

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in pediatric liver transplant patients

Ruth De BruyneMyriam Van WinckelPhilippe GevaertNatalie De RuyckDelfien BogaertBart LambrechtMelissa DullaersFrancoise SmetsEtienne SokalFréderic GottrandCharles Pilette

Role of B cell-activating factor in chronic obstructive pulmonary disease

Leen SeysFien VerhammeAnja SchinwaldHamida HammadDanen Mootoosamy CunoosamyClaudie Bantsimba-MalandaAlan SabirshEileen McCallLiz FlavellRonald HerbstSharen ProvoostBart LambrechtGuy JoosGuy BrusselleKen Bracke

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SnapShot: integrated type 2 immune responses

Bart LambrechtStephen J Galli

Editorial material

T-Helper 17 cell polarization in pulmonary arterial hypertension

Aurélie HautefortBarbara GirerdDavid MontaniSylvia Cohen-KaminskyLaura PriceBart LambrechtMarc HumbertFrédéric Perros

A1 Journal Article in CHEST

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

Mary van HeldenSteven GoossensCécile DaussyAnne-Laure MathieuFabrice FaureAntoine MarçaisNiels VandammeNatalie FarlaKatia MayolSébastien VielSophie DegouveEmilie DebienEve SeuntjensAndrea ConidiJulie ChaixPhilippe MangeotSimon de BernardLaurent BuffatJody HaighDanny HuylebroeckBart LambrechtGeert BerxThierry Walzer

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The immunology of asthma

Bart LambrechtHamida Hammad

A1 Journal Article in NATURE IMMUNOLOGY

The mucosal immune response to respiratory viruses

Bart LambrechtKatrijn NeytMary van Helden

Bookchapter in Mucosal immunology

The potential of radiotherapy to enhance the efficacy of renal cell carcinoma therapy

Katrien De WolfKarim VermaelenGert De MeerleerBart LambrechtPiet Ost

A1 Journal Article in ONCOIMMUNOLOGY

Type III collagen is important for collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckeBart LambrechtPatrick SegersAnne De PaepeSophie JanssensMathieu BertrandFransiska Malfait

Type III collagen is important for type I collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckePatrick SegersBart LambrechtAnne De PaepeSophie JanssensMathieu BertrandFransiska Malfait

Van hygiënehypothese tot theorie

P VankrunkelsvenM FinoulstHamida HammadBart Lambrecht

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2014

A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis

Koen VenkenSylvie SeeuwsLennart ZabeauPeggy JacquesTine DecruyJulie CoudenysEveline VerheugenFien WindelsDominiek CatteeuwMichael DrennanSerge Van CalenberghBart LambrechtAkihiko YoshimuraJan TavernierDirk Elewaut

A1 Journal Article in JOURNAL OF HEPATOLOGY

A case of dendritic cell, monocyte, B and NK lymphoid deficiency (DCML)

Melissa DullaersTessa KerreFrauke CoppietersDorine SichienNancy De CabooterVeronique DebackerReinhart SpeeckaertPaul CouckeElias DebaereFilomeen HaerynckBart LambrechtKarim Vermaelen

A novel Stat1 mutation leading to hyperphosphorylation in a patient with Pneumocystis jjiroveci and chronic mucocutaneous candidiasis

Melissa DullaersJens StaalSarah GerloElien VandermarliereV DebackerMaria Bordon Cueto De BraemK De WaeleI MeytsL MoensX BossuytFrans De BaetsBart LambrechtKarim VermaelenFilomeen Haerynck

A20-Deficient mast cells exacerbate inflammatory responses in vivo

Klaus HegerKaat FierensJ Christoph VahlAttila AszodiKatrin PeschkeDominik SchentenHamida HammadRudi BeyaertDieter SaurGeert van LooAxel RoersBart LambrechtMirjam KoolMarc Schmidt-Supprian

A1 Journal Article in PLOS BIOLOGY

Allergens and the airway epithelium response: gateway to allergic sensitization

Bart LambrechtHamida Hammad

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allopurinol reduces seizure severity and the inflammatory response in a mouse model for status epilepticus: a potential role for uric acid in ictogenesis

Lisa ThyrionRobrecht RaedtElke YdensSophie JanssensJulie KipsPieter Van LooJeanelle PortelliBart LambrechtAlfred MeursKristl VonckPaul Boon

Antigen-presenting dendritic cells

Bart LambrechtHamida Hammad

Bookchapter in Middleton's allergy : principles & practice

Clinical presentation of hyper-IgE syndrome in a family with impaired IL-22 production and STAT3 phosphorylation

Filomeen HaerynckDelfien BogaertElfride De BaereBart LambrechtKarim VermaelenVeronique DebackerKristof Van SchilFrans De BaetsPetra SchelstraeteMaria Bordon Cueto De BraemMelissa Dullaers

Dendritic cell and epithelial cell interactions at the origin of murine asthma

Bart LambrechtHamida Hammad

A2 Journal Article in ANNALS OF THE AMERICAN THORACIC SOCIETY

Dendritic cells

Bookchapter in Global atlas of allergy

Emerging functions of the unfolded protein response in immunity

Sophie JanssensBali PulendranBart Lambrecht

A1 Journal Article in NATURE IMMUNOLOGY

Enhancement of adaptive immunity by the human vaccine adjuvant AS01 depends on activated dendritic cells

Arnaud M DidierlaurentCatherine CollignonPatricia BourguignonSandrine WoutersKaat FierensMichel FochesatoNajoua DendougaChristelle LangletBernard MalissenBart LambrechtNathalie GarçonMarcelle Van MechelenSandra Morel

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Flow cytometric sexing of spider sperm reveals an equal sperm production ratio in a female-biased species

Bram VanthournoutKim DeswarteHamida HammadT BildeBart LambrechtFrederik Hendrickx

A1 Journal Article in BIOLOGY LETTERS

How to generate large numbers of CD103⁺ dendritic cells

Lianne van de LaarBart Lambrecht

Editorial material

Immunity induced by a broad class of inorganic crystalline materials is directly controlled by their chemistry

Gareth R WilliamsKaat FierensStephen G PrestonDaniel LunnOliwia RysnikSofie De PrijckMirjam KoolHannah C BuckleyBart LambrechtDermot O'HareJonathan M Austyn

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Innate immune cells to the help

Bart LambrechtHamida Hammad

Editorial material

Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level

Lotte PyfferoenPieter MestdaghKarl VergoteNancy De CabooterJo VandesompeleBart LambrechtKarim Vermaelen

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Monocytes find a new place to dwell in the niche of heartbreak hotel

Bart LambrechtMartin Guilliams

Editorial material

Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers

Marijke DierendonckKaat FierensRiet De RyckeLien LybaertSamarendra MajiZhiyue ZhangQilu ZhangRichard HoogenboomBart LambrechtJohan GrootenJean Paul RemonStefaan De KokerBruno De Geest

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Nanoporous polyelectrolyte vaccine microcarriers: a formulation platform for enhancing humoral and cellular immune responses

Stefaan De KokerKaat FierensMarijke DierendonckRiet De RyckeBart LambrechtJohan GrootenJean Paul RemonBruno De Geest

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Ontogeny of myeloid cells

Ismé De KleerFabienne WillemsBart LambrechtStanislas Goriely

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Temporal dynamics and therapeutic potential of the unfolded protein espouse in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis LibbrechtRiet De RyckeBart LambrechtSophie Janssens

Temporal dynamics and therapeutic potential of the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis LibbrechtRiet De RyckeBart LambrechtS JanssensHans Van Vlierberghe

The function of Fcγ receptors in dendritic cells and macrophages

Martin GuilliamsPierre BruhnsYvan SaeysHamida HammadBart Lambrecht

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α⁺ dendritic cells

Fabiola OsorioSimon TavernierEik HoffmannYvan SaeysLiesbet MartensJessica VettersIris DelrueRiet De RyckeEef ParthoensPhilippe PouliotTakao IwawakiSophie JanssensBart Lambrecht

A1 Journal Article in NATURE IMMUNOLOGY

Therapeutic effects of artesunate in hepatocellular carcinoma : repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteLouis LibbrechtBart LambrechtS JanssensHans Van Vlierberghe

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsIsabelle ColleLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteLouis LibbrechtBart LambrechtSophie JanssensHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

2013

Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance

Franz PutturCatharina Arnold-SchraufKatharina LahlGulhas SolmazMarc LindenbergChristian Thomas MayerMelanie GohmertMaxine SwallowChristopher van HeltHeike SchmittLars NitschkeBart LambrechtRoland LangMartin MesserleTim Sparwasser

A1 Journal Article in PLOS PATHOGENS

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Martin GuilliamsIsmé De KleerSandrine HenriSijranke PostLeen VanhoutteSofie De PrijckKim DeswarteBernard MalissenHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Asthma and coagulation

Bart LambrechtHamida Hammad

Editorial material

Asthma: the importance of dysregulated barrier immunity

Bart LambrechtHamida Hammad

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Bacterial CD1d-restricted glycolipids induce IL-10 production by human regulatory T cells upon cross-talk with invariant NKT cells

Koen VenkenTine DecruySANDRINE ASPESLAGHSerge Van CalenberghBart LambrechtDirk Elewaut

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Conventional and monocyte-derived CD11b⁺ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen

Maud PlantingaMartin GuilliamsManon VanheerswynghelsKim DeswarteFilipe Branco MadeiraWendy ToussaintLeen VanhoutteKatrijn NeytNigel KilleenBernard MalissenHamida HammadBart Lambrecht

A1 Journal Article in IMMUNITY

Cytokine targets in airway inflammation

Martijn SchuijsMonique WillartHamida HammadBart Lambrecht

A1 Journal Article in CURRENT OPINION IN PHARMACOLOGY

Death at the airway epithelium in asthma

Bart LambrechtHamida Hammad

Editorial material

Dendritic cells in asthma

Mary van HeldenBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

Martin GuilliamsBart LambrechtHamida Hammad

A1 Journal Article in MUCOSAL IMMUNOLOGY

Immune activation at the lung epithelial barrier

Monique WillartHamida HammadBart Lambrecht

Mycobacterium tuberculosis manipulates pulmonary APCs subverting early immune responses

Gina S Garcia-RomoAlexander Pedroza-GonzalezBart LambrechtDiana Aguilar-LeonIris Estrada-GarciaRogelio Hernandez-PandoLeopoldo Flores-Romo

A1 Journal Article in IMMUNOBIOLOGY

Natural and long-lasting cellular immune responses against influenza in the M2e-immune host

Michael SchotsaertTine YsenbaertKristien NeytsLorena IbanezPieter BogaertBert SchepensBart LambrechtWalter FiersXavier Saelens

A1 Journal Article in MUCOSAL IMMUNOLOGY

PAMPs and DAMPs in allergy exacerbation models

Monique WillartPhilippe PoulliotBart LambrechtMirjam Kool

Bookchapter in Mouse models in allergic disease : methods and protocols

Pooling birth cohorts in allergy and asthma: European Union-funded initiatives: a MeDALL, CHICOS, ENRIECO, and GA²LEN joint paper

Jean BousquetJosep AntoJordi SunyerMark NieuwenhuijsenMartine VrijheidThomas Keilthe MeDALL Study GroupBart LambrechtClaus Bachertthe GA²LEN Study GroupPaul Van Cauwenbergethe CHICOS Study Groupthe ENRIECO Study Group

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Potential of immunoglobulin A to prevent allergic asthma

Anouk K GloudemansBart LambrechtHermelijn H Smits

A1 Journal Article in CLINICAL & DEVELOPMENTAL IMMUNOLOGY

Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease

Ken BrackeFien VerhammeLeen SeysClaudie Bantsimba-MalandaDanen Mootoosamy CunoosamyRonald HerbstHamida HammadBart LambrechtGuy JoosGuy Brusselle

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Short cigarette smoke exposure facilitates sensitisation and asthma development in mice

Ellen LanckackerKurt TournoyHamida HammadGabriële HoltappelsBart LambrechtGuy JoosTania Maes

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Temporal dynamics of the unfolded protein response and chemoresistance in hepatocellular carcinoma

Yves-Paul VandewynckelIsabelle ColleDebby LaukensBart LambrechtBenedicte DescampsChristian VanhoveHans Van Vlierberghe

The European Respiratory Society fellowship programme: supporting young careers and building networks

Robert BalsJosephine Ricou YanmazCéline SchaffterCarine PannetierNadia KamelRoelinde MiddelveldSvan-Erik DahlénBart LambrechtBenoit NemeryLaurent NicodStephen Holgate

Editorial material

The UPR and lung disease

Fabiola OsorioBart LambrechtSophie Janssens

A1 Journal Article in SEMINARS IN IMMUNOPATHOLOGY

The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β

Anouk K GloudemansMaud PlantingaMartin GuilliamsMonique WillartArifa Ozir-FazalalikhanAlwin van der HamLouis BoonNicola L HarrisHamida HammadHenk C HoogstedenMaria YazdanbakhshRudi W HendriksBart LambrechtHermelijn H Smits

A1 Journal Article in PLOS ONE

The multi-faceted role of allergen exposure to the local airway mucosa

K GolebskiKIL RoschmannS Toppila-SalmiHamida HammadBart LambrechtR RenkonenWJ FokkensCM van Drunen

A1 Journal Article in ALLERGY

The pathogenesis of pulmonary fibrosis: a moving target

Wim A WuytsCarlo AgostiniKaterina M AntoniouDemosthenes BourosRacherl C ChambersVincent CottinJim J EganBart LambrechtRik LoriesHelen ParfreyAntje PrasseCarlos Robalo-CordeiroEric VerbekenJohny A VerschakelenAthol U WellsGeert M Verleden

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The role of lung dendritic cell subsets in immunity to respiratory viruses

Katrijn NeytBart Lambrecht

A1 Journal Article in IMMUNOLOGICAL REVIEWS

The therapeutic potential of artesunate in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsIsabelle ColleLouis LibbrechtEliene BogaertsLindsey DevisscherAnnelies ParidaensXavier VerhelstChristian VanhoveBenedicte DescampsSophie JanssensBart LambrechtChristophe Van SteenkisteHans Van Vlierberghe

Topical treatment targeting sphingosine-1-phosphate and sphingosine lyase abrogates experimental allergic rhinitis in a murine model

A KleinJanM van NimwegenK LemanHC HoogstedenBart Lambrecht

A1 Journal Article in ALLERGY

2012

A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma

Laurent L ReberFrançois DaubeufMaud PlantingaLode De CauwerSarah GerloWim WaelputSerge Van CalenberghJan TavernierGuy HaegemanBart LambrechtNelly FrossardKarolien De Bosscher

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1

Jonathan ElegheertNathalie BrackePhilippe PouliotIrina GutscheAlexander V ShkumatovNicolas TarbouriechKenneth VerstraeteAnaïs BekaertWim P BurmeisterDmitri I SvergunBart LambrechtBjorn VergauwenSavvas Savvides

A1 Journal Article in NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alum adjuvant: some of the tricks of the oldest adjuvant

Mirjam KoolKaat FierensBart Lambrecht

A1 Journal Article in JOURNAL OF MEDICAL MICROBIOLOGY

Alveolar preservation with high inflation pressure and intermediate oxygen concentration reduces ischemia-reperfusion injury of the lung

Niels P van der KaaijJolanda KluinRobert A LachmannMichael A den BakkerBart LambrechtBurkhard LachmannRon WF de BruinAd JJC Bogers

A1 Journal Article in JOURNAL OF HEART AND LUNG TRANSPLANTATION

Cellular networks controlling Th2 polarization in allergy and immunity

Mirjam KoolHamida HammadBart Lambrecht

A2 Journal Article in F1000 BIOLOGY REPORTS

Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy

H MaaziS ShirinbakMonique WillartHamida HammadM CabanskiL BoonV GaneshAM BaruG HansenBart LambrechtT SparwasserMC NawijnAJM van Oosterhout

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Development of a novel COL3A1 transgenic mouse model for vascular Ehlers Danlos Syndrome

Yike KangSofie SymoensFransiska MalfaitPaul CouckeMarjolijn RenardBrecht GuillemynJulie De BackerFilipe Branco MadeiraWendy ToussaintLeen VanhoutteSophie JanssensBenedicte DescampsChristian VanhovePatrick SegersBart LambrechtAnne De Paepe

Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses

M SemmrichMaud PlantingaM Svensson-FrejH Uronen-HanssonT GustafssonAM MowatU YrlidBart LambrechtWW Agace

A1 Journal Article in MUCOSAL IMMUNOLOGY

Engineered 3D microporous gelatin scaffolds to study cell migration

Liesbeth De CockOlivier De WeverHamida HammadBart LambrechtEls VanderleydenPeter DubruelFilip De VosChris VervaetJean Paul RemonBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

Evidence for local dendritic cell activation in pulmonary sarcoidosis

Bregje Ten BergeAlex KleinJanFemke MuskensHamida HammadHenk C HoogstedenRudi W HendriksBart LambrechtBernt Van den Blink

A1 Journal Article in RESPIRATORY RESEARCH

IL-21 is increased in nasal polyposis and after stimulation with Staphylococus aureus enterotoxins

LIEN CALUSIne DeryckeNatalie De RuyckGabriële HoltappelsMelissa DullaersBart LambrechtClaus BachertPhilippe Gevaert

Increased IL-17A expression in granulomas and in circulating memory T cells in sarcoidosis

Bregje ten BergeMarthe S PaatsIngrid M BergenBernt van den BlinkHenk C HoogstedenBart LambrechtRudi W HendriksAlex KleinJan

A1 Journal Article in RHEUMATOLOGY

Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33

Monique WillartKim DeswartePhilippe PouliotHarald BraunRudi BeyaertBart LambrechtHamida Hammad

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Lung dendritic cells in respiratory viral infection and asthma : from protection to immunopathology

Bart LambrechtHamida Hammad

A1 Journal Article in Annual Review of Immunology

Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection

Bruno De GeestMonique WillartHamida HammadBart LambrechtCharlotte PollardPieter BogaertMarina De FiletteXavier SaelensChris VervaetJean Paul RemonJohan GrootenStefaan De Koker

A1 Journal Article in ACS NANO

Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension

Frédèric PerrosPeter DorfmüllerDavid MontaniHamida HammadWim WaelputBarbara GirerdNicolas RaymondOlaf MercierSacha MussotSylvia Cohen-KaminskyMarc HumbertBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SCID-like symptoms in a patient with chronic mucocutaneous candidiasis caused by STAT1 mutation

Melissa DullaersMaria Bordon Cueto De BraemK De WaeleI MeytsL MoensX BossuytKarim VermaelenBart LambrechtF De BaetsFilomeen Haerynck

Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function

Bruno De GeestMonique WillartBart LambrechtCharlotte PollardChris VervaetJean Paul RemonJohan GrootenStefaan De Koker

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets

Trudy StraetemansMandy van BrakelSabine van SteenbergenMarieke BroertjesJoost DrexhageJoost HegmansBart LambrechtCor LamersPierre van der BruggenPierre G CoulieReno Debets

A1 Journal Article in CLINICAL & DEVELOPMENTAL IMMUNOLOGY

Tertiary lymphoid organs in infection and autoimmunity

Katrijn NeytFrédéric PerrosCorine H GeurtsvanKesselHamida HammadBart Lambrecht

A1 Journal Article in TRENDS IN IMMUNOLOGY

The airway epithelium in asthma

Bart LambrechtHamida Hammad

A1 Journal Article in NATURE MEDICINE

The who, where, and when of IgE in allergic airway disease

Melissa DullaersRuth De BruyneFaruk RamadaniHannah J GouldPhilippe GevaertBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar

Josep M AntóMariona PinartMübeccel AkdisCharles AuffrayClaus BachertXavier BasagañaKai-Håkon CarlsenStefano GuerraLeena von HertzenSabina IlliFrancine KauffmannThomas KeilJames P KileyGerard H KoppelmanChristian LupinekFernando D MartinezMartijn C NawijnDirkje S PostmaValérie SirouxHenriette A SmitPeter J SterkJordi SunyerRudolf ValentaSergio ValverdeCezmi A AkdisIsabella Annesi-MaesanoFerran BallesterMarta BenetAnne Cambon-ThomsenLeda ChatziJonathan CoquetPascal DemolyWeiniu GanJudith Garcia-AymerichElena Gimeno-SantosChantal Guihenneuc-JouyauxTari HaahtelaJoachim HeinrichMarie HerrCynthia HohmannBénédicte JacqueminJocelyne JustMarjan KerkhofManolis KogevinasMarek L KowalskiBart LambrechtSusanne LauKarin C Lødrup CarlsenDieter MaierIsabelle MomasPatricia NoelSam OddieSusanna PalkonenIsabelle PinDaniela PortaAntonello PunturieriFanny RancièreRobert A SmithBarbara StanicRenato T SteinWillem van de VeenAntoon JM van OosterhoutRaphaelle VarrasoMagnus WickmanCisca WijmengaJohn WrightGorkem YamanTorsten ZuberbierJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor

Monique WillartM van NimwegenA GrefhorstHamida HammadL MoonsHC HoogstedenBart LambrechtA KleinJan

A1 Journal Article in ALLERGY

2011

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Mourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars VereeckeYuanyuan ChuLouis BoonSteven StaelensPatrick MatthysBart LambrechtMarc Schmidt-SupprianManolis PasparakisDirk ElewautRudi BeyaertGeert van Loo

A1 Journal Article in NATURE GENETICS

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Dirk ElewautMourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars VereeckeYuanyuan ChuSteven StaelensPatrick MatthysBart LambrechtMarc Schmidt-SupprianManolis PasparakisRudi BeyaertGeert van Loo

An unexpected role for uric Acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma

Mirjam KoolMonique WillartMenno van NimwegenIngrid BergenPhilippe PouliotJ Christian VirchowNeil RogersFabiola OsorioCaetano Reis E SousaHamida HammadBart Lambrecht

A1 Journal Article in IMMUNITY

Anti-inflammatory actions of phosphatidylinositol

Jolanda M van DierenYtje Simons-OosterhuisHC (Rolien) RaatgeepDicky J Lindenbergh-KortleveMargaretha EH LambersC Janneke van der WoudeErnst J KuipersGerry T SnoekRon PotmanHamida HammadBart LambrechtJanneke N SamsomEdward ES Nieuwenhuis

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

C-Kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension

David MontaniFrédéric PerrosNatalia GambaryanBarbara GirerdPeter DorfmullerLaura C PriceAlice HuertasHamida HammadBart LambrechtGérald SimonneauJean-Marie LaunaySylvia Cohen-KaminskyMarc Humbert

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

Diego Mourão-SáMatthew J RobinsonSantiago ZelenayDavid SanchoProbir ChakravartyRasmus LarsenMaud PlantingaNico Van RooijenMiguel P SoaresBart LambrechtCaetano Reis e Sousa

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Cigarette smoking alters epithelial apoptosis and immune composition in murine GALT

Stephanie VERSCHUEREKen BrackeTine DemoorMaud PlantingaPhebe VerbruggheLiesbeth FerdinandeBart LambrechtGuy BrusselleClaude Cuvelier

A1 Journal Article in LABORATORY INVESTIGATION

Cigarette smoking alters intestinal barrier function and Peyer's Patch composition

STEPHANIE VERSCHUEREKen BrackeTine DemoorMaud PlantingaBart LambrechtGuy BrusselleClaude Cuvelier

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

Hamida HammadBart Lambrecht

A1 Journal Article in ALLERGY

Designing polymeric particles for antigen delivery

Stefaan De KokerBart LambrechtMonique WillartYvette van KooykJohan GrootenChris VervaetJean Paul RemonBruno De Geest

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis

Nele FestjensPieter BogaertAnjana BatniErica HouthuysEvelyn PletsDieter VanderschaegheBram LaukensBob AsselberghEef ParthoensRiet De RyckeMonique WillartPeggy JacquesDirk ElewautPeter BrouckaertBart LambrechtKris HuygenNico Callewaert

A1 Journal Article in EMBO MOLECULAR MEDICINE

Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A

Anne-Gaelle BesnardRobert SabatLaure DumoutierJean-Christophe RenauldMonique WillartBart LambrechtMauro M TeixeiraSabine CharronLizette FickFrancois ErardKatarzyna WarszawskaKerstin WolkValerie QuesniauxBernhard RyffelDieudonnee Togbe

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

ERS is founding member of a new Alliance for Biomedical Research in Europe

LP NicodN KamelB WardM DecramerY SibilleBart LambrechtC DiveU SmithKR Sipido

Editorial material

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

Dmitri KryskoPatrizia AgostinisOlga KryskoAbhishek D GargClaus BachertBart LambrechtPeter Vandenabeele

A1 Journal Article in TRENDS IN IMMUNOLOGY

Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCs

Mirjam KoolCorine GeurtsVanKesselFemke MuskensFilipe Branco MadeiraMenno van NimwegenHarmjan KuipersKris ThielemansHenk C HoogstedenHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Highly pathogenic avian influenza virus H5N1 infects alveolar macrophages without virus production or excessive TNF-alpha induction

Debby van RielLonneke ME LeijtenMenno van der EerdenHenk C HoogstedenLeonie A BovenBart LambrechtAlbert DME OsterhausThijs Kuiken

A1 Journal Article in PLOS PATHOGENS

Initiation and maintenance of allergic inflammation: team work at the interface of innate and adaptive immunity

Bart LambrechtDonald YM Leung

Editorial material

Involvement of endoplasmic reticulum stress in inflammatory bowel disease : a different implication for colonic and ileal disease?

Sara BogaertMartine De VosKim OlievierHarald PeetersDirk ElewautBart LambrechtPhilippe PouliotDebby Laukens

A1 Journal Article in PLOS ONE

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine

J BousquetJ AntoC AuffrayM AkdisA Cambon-ThomsenT KeilT HaahtelaBart LambrechtDS PostmaJ SunyerR ValentaCA AkdisI Annesi-MaesanoA ArnoClaus BachertF BallesterX BasaganaU BaumgartnerC Bindslev-JensenB BrunekreefKH CarlsenL ChatziR CrameriE EvenoF ForastiereJ Garcia-AymerichS GuerraHamida HammadJ HeinrichD HirschB JacqueminF KauffmannM KerkhofM KogevinasGH KoppelmanML KowalskiS LauKC Lodrup-CarlsenM Lopez-BotetJ LotvallC LupinekD MaierMJ MakelaFD MartinezJ MestresI MomasMC NawijnA NeubauerS OddieS PalkonenI PinC PisonF RancéS ReitamoE Rial-SebbagM SalapatasV SirouxD SmaggheM TorrentE ToskalaPaul Van CauwenbergeAJM van OosterhoutR VarrasoL von HertzenM WickmanC WijmengaM WormJ WrightT Zuberbier

A1 Journal Article in ALLERGY

NLRP3/Caspase-1-independent IL-1β production mediates diesel exhaust particle-induced pulmonary inflammation

Sharen ProvoostTania MaesNele PauwelsTom Vanden BerghePeter VandenabeeleBart LambrechtGuy JoosKurt Tournoy

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Novel anti-inflammatory drugs based on targeting lung dendritic cells and airway epithelial cells

Bart LambrechtMaud PlantingaMonique WillartHamida Hammad

Bookchapter in Inflammation and allergy drug design

Persistent activation of dendritic cells after resolution of allergic airway inflammation breaks tolerance to inhaled allergens in mice

Leonie van RijtNanda VosMonique WillartFemke MuskensPaul P TakCorine van der HorstHenk C HoogstedenBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pulmonary defence mechanisms and inflammatory pathways in bronchiectasis

Bart LambrechtKatrijn NeytCH GeurtsvanKessel

Bookchapter in Bronchiectasis

Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD

NS PauwelsKen BrackeLisa DupontGeert Van PottelbergeSharen ProvoostTom Vanden BerghePeter VandenabeeleBart LambrechtGuy JoosGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways

Frédèric PerrosBart LambrechtHamida Hammad

A1 Journal Article in RESPIRATORY RESEARCH

TNF driven activation of invariant NKT cells regulates combined gut and joint inflammation

Peggy JacquesSylvie SeeuwsHamida HammadBart LambrechtGeorge KolliasMartine De VosDirk Elewaut

The neuropeptide calcitonin gene-related peptide affects allergic airway inflammation by modulating dendritic cell function

S RochlitzerTZ VeresK KühneF PrenzlerC PilznerS KnotheC WinklerHD LauensteinMonique WillartHamida HammadM MüllerN KrugBart LambrechtA Braun

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation

Tine DemoorKen BrackeLisa DupontMaud PlantingaBenjamin BondueMarie-Odile RoyVincent LannoyBart LambrechtGuy BrusselleGuy Joos

A1 Journal Article in JOURNAL OF IMMUNOLOGY

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity

Mirjam KoolGeert van LooWim WaelputSofie De PrijckFemke MuskensMozes SzeJens Van PraetFilipe Branco MadeiraSophie JanssensBoris ReizisDirk ElewautRudi BeyaertHamida HammadBart Lambrecht

A1 Journal Article in IMMUNITY

2010

Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma

Joost P HegmansJoris D VeltmanMargaretha E LambersJolanda M de VriesCarl G FigdorRudi W HendriksHenk C HoogstedenBart LambrechtJoachim G Aerts

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Diesel exhaust particles stimulate adaptive immunity by acting on pulmonary dendritic cells

Sharen ProvoostTania MaesMonique WillartGuy JoosBart LambrechtKurt Tournoy

A1 Journal Article in Journal of Immunology

Flow cytometric differentiation of avian leukocytes and analysis of their intracellular cytokine expression

Sandra De BoeverSiska CroubelsKristel DemeyereBart LambrechtPatrick De BackerEvelyne Meyer

A1 Journal Article in AVIAN PATHOLOGY

High mobility group box-1 recognition : the beginning of a RAGEless era?

Filipe Branco MadeiraBart Lambrecht

Editorial material

Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

Hamida HammadMaud PlantingaKim DeswartePhilippe PouliotMonique WillartMirjam KoolFemke MuskensBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Invariant natural killer T cells are natural regulators of murine spondylarthritis

Peggy JacquesKoen VenkenKatrien Van BenedenHamida HammadSylvie SeeuwsMichael DrennanDieter DeforceAugust VerbruggenMaria ApostolakiGeorge KolliasBart LambrechtMartine De VosDirk Elewaut

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype

Niek P van TilMerel StokFatima SF Aerts KayaMonique C de WaardElnaz FarahbakhshianTrudi P VisserMarian A KroosEdwin H JacobsMonique WillartPascal van der WegenBob J ScholteBart LambrechtDirk J DunckerAns T van der PloegArnold JJ ReuserMonique M VerstegenGerard Wagemaker

A1 Journal Article in BLOOD

Origin and functional specializations of DC subsets in the lung

Maud PlantingaHamida HammadBart Lambrecht

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma

Wouter HuvenneIna CallebautMaud PlantingaJeroen AJ VanoirbeekOlga KryskoDominique MA BullensPhilippe GevaertPaul Van CauwenbergeBart LambrechtJan L CeuppensClaus BachertPeter W Hellings

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Studying the function of dendritic cells in mouse models of asthma

Philippe PouliotMonique WillartHamida HammadBart Lambrecht

Bookchapter in Dendritic cell protocols

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice

Soheila ShirinbakYousef A TaherHadi MaaziRenee GrasBetty CAM van EschPaul AJ HenricksJanneke N SamsomJ Sjef VerbeekBart LambrechtAntoon JM van OosterhoutMartijn C Nawijn

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Suppression of human natural killer T cell function by CD4(+)CD25(+)FOXP3(+) regulatory T cells

Koen VenkenTine DecruyKim DeswarteSANDRINE ASPESLAGHSerge Van CalenberghBart LambrechtDirk Elewaut

T-cell regulation of neutrophil infiltrate at the early stages of a murine colitis model

Pieter PE van LieropColin de HaarDicky J Lindenbergh-KortleveYtje Simons-OosterhuisLeonie S van RijtBart LambrechtJohanna C EscherJanneke N SamsomEdward ES Nieuwenhuis

A1 Journal Article in INFLAMMATORY BOWEL DISEASES

The role of dendritic and epithelial cells as master regulators of allergic airway inflammation

Bart LambrechtHamida Hammad

A1 Journal Article in LANCET

United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation

Alex KleinjanMonique WillartMenno van NimwegenKarolina LemanHenk HoogstedenRudy HendriksBart Lambrecht

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Vegf regulates embryonic erythroid development through Gata1 modulation

Benjamin DrogatJoanna KaluckaLaura GutierrezHamida HammadSteven GoossensMorvarid Farhang GhahremaniSona BartunkovaKatharina HaighKim DeswarteOmar NyabiMichaël NaessensNapoleone FerraraUursula KlingmullerBart LambrechtAndras NagySjaak PhilipsenJody Haigh

A1 Journal Article in BLOOD

2009

A novel method for isolating dendritic cells from human bronchoalveolar lavage fluid

B Ten BergeF MuskensA KleinJanHamida HammadHC HoogstedenBart LambrechtB Van den Blink

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation

Mirjam KoolMenno van NimwegenMonique WillartFemke MuskensLouis BoonJoost SmitAnthony CoyleBjörn ClausenHenk HoogstedenBart LambrechtHamida Hammad

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Biology of lung dendritic cells at the origin of asthma

Bart LambrechtHamida Hammad

A1 Journal Article in IMMUNITY

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

Frédèric PerrosH.C. HoogstedenA.J. CoyleBart LambrechtHamida Hammad

A1 Journal Article in Allergy

Both Conventional and Interferon Killer Dendritic Cells Have Antigen-Presenting Capacity during Influenza Virus Infection

CH GeurtsvanKesselIM BergenF MuskensL BoonHC HoogstedenADME OsterhausGF RimmelzwaanBart Lambrecht

A1 Journal Article in PLOS ONE

Cholera toxin B suppresses allergic inflammation through induction of secretory IgA

H. SmitsA. GloudemansM. van NimwegenMonique WillartT. SoulliéF. MuskensE. de JongL. BoonC. PiletteF.-E. JohansenH. HoogstedenHamida HammadBart Lambrecht

A1 Journal Article in Mucosal Immunology

Chronic airway inflammation promotes de novo sensitisation to inhaled allergens by persistent activation of dendritic cells

L van RijtN VosF MuskensMonique WillartH HoogstedenBart Lambrecht

Chronic airway inflammation promotes de novo sensitization to inhaled allergen by persistent activation of dendritic cells

LS Van RijtN VosMonique WillartF MuskensH HoogstedenBart Lambrecht

Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4

F BroereMF Du PréLA Van BerkelJ GarssenCB Schmid-WeberBart LambrechtRW HendriksEES NieuwenhuisG KraalJN Samsom

A1 Journal Article in MUCOSAL IMMUNOLOGY

De rol van de dendritische cel in astma

Monique WillartBart Lambrecht

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Dendritic cell-based immunotherapy for malignant pleural mesothelioma

JG AertsJ VeltmanM LambersBart LambrechtHC HoogstedenJJ Hegmans

Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice

Corine H GeurtsvanKesselMonique WillartIngrid M BergenLeonie S van RijtFemke MuskensDirk ElewautAlbert DLE OsterhausRudi HendriksGuus F RimmelzwaanBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic cells in rhinitis

A KleinjanBart Lambrecht

Bookchapter in Dendritic cells

Effect of Cigarette Smoke Extract on Dendritic Cells and Their Impact on T-Cell Proliferation

E MortazAD KraneveldJJ SmitMirjam KoolBart LambrechtSL KunkelNW LukacsFP NijkampG Folkerts

A1 Journal Article in PLOS ONE

Function of dendritic cell subsets in allergic disease

Bart LambrechtHamida Hammad

Bookchapter in Allergy frontiers : classification and pathomechanisms

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

Hamida HammadMarcello ChieppaFrédèric PerrosMonique WillartRonald GermainBart Lambrecht

A1 Journal Article in Nature Medicine

Immune Suppression Feature of Ursodeoxycholic Acid is DC-mediated as Measured in Eosinophilic Airway Inflammation Model

A. KleinjanMonique WillartHamida HammadM. van NimwegenL. MoonsH.C. HoogstedenBart Lambrecht

Lung dendritic cells: targets for therapy in allergic disease

Bart LambrechtHamida Hammad

Bookchapter in Dendritic cells

Mechanism of action of clinically approved adjuvants

Bart LambrechtMirjam KoolMonique WillartHamida Hammad

A1 Journal Article in Current opinion in Immunology

Protein Profiling of Pleural Effusions to Identify Malignant Pleural Mesothelioma Using SELDI-TOF MS

Joost HegmansJoris VeltmanEric FungThorsten VerchCurtis GloverFujun ZhangW. Jeffrey AllardDavy T'JampensHenk HoogstedenBart LambrechtJoachim Aerts

A1 Journal Article in Technology in cancer research and treatment

Protein tyrosine phosphatases regulate asthma development in a murine asthma model

Philippe PouliotPierre CamaterosDanuta RadziochBart LambrechtMartin Olivier

A1 Journal Article in Journal of Immunology

Selective control of SIRP-α-positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation

M RaymondM RubioG FortinKH ShalabyHamida HammadBart LambrechtM Sarfati

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells

Harmjan KuipersThomas SoullieHamida HammadMonique WillartMirjam KoolDanielle HijdraHenk HoogstedenBart Lambrecht

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Surfactant pretreatment decreases long-term damage after ischemia-reperfusion injury of the lung

Niels van der KaaijJolanda KluinJack HaitsmaMichael den BakkerBart LambrechtBurkhard LachmannRon de BruinAd Bogers

A1 Journal Article in EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Technical note: Flow cytometric identification of bovine milk neutrophils and simultaneous quantification of their viability

Sofie PiepersSarne De VliegherKristel DemeyereBart LambrechtAart de KruifEvelyne MeyerGeert Opsomer

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

The danger within: endogenous danger signals, atopy and asthma

Monique WillartBart Lambrecht

A1 Journal Article in Clinical and Experimental Allergy

The influence of oxygen concentration and inflation pressure during ischemia on lung ischemia reperfusion injury

NP van der KaaijJ KluinRA LachmannMA den BakkerJJ HaitsmaBart LambrechtRWF de BruinB LachmannAJJC Bogers

The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen

Monique WillartHendrik Jan de HeerHamida HammadThomas SoulliéKim DeswarteBjörn E ClausenLouis BoonHenk C HoogstedenBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The novel adjuvant CoVaccineHT (TM) increases the immunogenicity of cell-culture derived influenza A/H5N1 vaccine and induces the maturation of murine and human dendritic cells in vitro

R BodewesMM Geelhoed-MierasJGM HeldensJ GloverBart LambrechtRAM FouchierADME OsterhausGF Rimmelzwaan

A1 Journal Article in VACCINE

2008

'United airways': Allergic rhinitis exacerbates lower airway inflammation is controlled by cellular and neurogenic processes in a mouse model

A KLEINJANMonique WillartK LEMANHC HOOGSTEDENBart Lambrecht

Altered expression of epithelial junctional proteins in atopic asthma: possible role in inflammation

WI DE BOERHS SHARMASMI BAELEMANSHC HOOGSTEDENBart LambrechtGJ BRAUNSTAHL

A1 Journal Article in CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

M KOOLT SOULLIEM VAN NIMWEGENMonique WillartF MUSKENSS JUNGHC HOOGSTEDENHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

Mirjam KoolVirginie PetrilliThibaut De SmedtAline RolazHamida HammadMenno van NimwegenIngrid M. BergenRosa CastilloBart LambrechtJuerg Tschopp

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Antigen-presenting dendritic cells

Bart LambrechtHamida Hammad

Bookchapter in Middleton's allergy : principles & practice

Antigen‐presenting dendritic cells and macrophages

Bart LambrechtHamida Hammad

Bookchapter in Allergy and allergic diseases

Clearance of influenza virus from the lung depends on migratory langerin(+)CD11b(-) but not plasmacytoid dendritic cells

CH GEURTSVANKESSELMonique WillartLS VAN RIJTF MUSKENSM KOOLC BAASK THIELEMANSC BENNETTBE CLASENHC HOOGSTEDENADME OSTERHAUSGF RIMMELZWAANBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

De rol van de dendritische cel in astma

Monique WillartBart Lambrecht

A3 Journal Article in Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde

De rol van de dendritische cel in astma

Monique WillartBart Lambrecht

A4 Journal Article in Analyse

Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma

Hamida HammadBart Lambrecht

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

Division of labor between dendritic cell subsets of the lung

C. GeurtsvanKesselBart Lambrecht

A1 Journal Article in MUCOSAL IMMUNOLOGY

IL-2 producing memory CD4+ T lymphocytes are closely associated with the generation of IgG-secreting plasma cells

Nicolle HR LitjensMartin HuismanDanielle HijdraBart LambrechtKoert J StittelaarMichiel GH Betjes

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA(2)LEN paper

J BousquetW FokkensP BurneySR DurhamClaus BachertCA AkdisGW CanonicaSE DahlenT ZuberbierT BieberS BoniniPJ BousquetJL BrozekLO CardellR CrameriA CustovicP DemolyRG Van WijkM GjomarkajC HollandP HowarthM HumbertSL JohnstonF KauffmannML KowalskiBart LambrechtS LehmannB LeynaertK Lodrup-CarlsenJ MullolB NiggemannE Nizankowska-MogilnickaN PapadopoulosG PassalacquaHJ SchunemannHU SimonA Todo-BomE ToskalaR ValentaM WickmanJP Zock

A1 Journal Article in ALLERGY

Inducible costimulator blockade prolongs airway lumnal patency in a mouse model of obliterative bronchiolitis

Alex KleinJanMonique WillartHarmjan KuipersAnthony J. CoyleHenk C. HoogstedenBart Lambrecht

A1 Journal Article in Transplantation

Ischemia of the lung causes extensive long-term pulmonary injury: an experimental study

NP VAN DER KAAIJJ KLUINJJ HAITSMAMA DEN BAKKERBart LambrechtB LACHMANNRWF DE BRUINAJJC BOGERS

A1 Journal Article in RESPIRATORY RESEARCH

Lung dendritic cells are stimulated by ultrafine particles and play a key role in particle adjuvant activity

C DE HAARM KOOLI HASSINGM BOLBart LambrechtR PIETERS

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lung dendritic cells: Targets for therapy in allergic disease

A1 Journal Article in CURRENT MOLECULAR MEDICINE

Proteomics in pleural disease

Joost HegmansBart Lambrecht

Bookchapter in Textbook of pleural diseases

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection

A DIDIERLAURENTJ GOULDINGS PATELR SNELGROVEL LOWM BEBIENT LAWRENCELS VAN RIJTBart LambrechtJC SIRARDT HUSSELL

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The balance between plasmacytoid DC versus conventional DC determines pulmonary immunity to virus infections

Joost J SmitDennis M LindellLouis BoonMirjam KoolBart LambrechtNicholas W Lukacs

A1 Journal Article in PLOS ONE

2007

Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells

Hamida HammadM KOOLT SOULLIES NARUMIYAF TROTTEINHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Cells meeting our immunophenotypic criteria of endothelial cells are large platelets

MH STRIJBOSJ KRAANMA DEN BAKKERBart LambrechtS SLEIJFERJW GRATAMA

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Dendritic cells in asthma and COPD: opportunities for drug development

M KOOLBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

M IDZKOHamida HammadM VAN NIMWEGENM KOOLMonique WillartF MUSKENSHC HOOGSTEDENW LUTTMANND FERRARIF DI VIRGILIOJC VIRCHOWBart Lambrecht

A1 Journal Article in NATURE MEDICINE

GATA3-driven Th2 responses inhibit TGF-beta 1-induced FOXP3 expression and the formation of regulatory T cells

PY MANTELH KUIPERSO BOYMANC RHYNERN OUAKEDB RUCKERTC KARAGIANNIDISBart LambrechtRW HENDRIKSR CRAMERICA AKDISK BLASERCB SCHMIDT-WEBER

A1 Journal Article in PLOS BIOLOGY

Gata1 regulates dendritic-cell development and survival

Laura GutiérrezTatjana NikolicThamar B van DijkHamida HammadNanda VosMonique WillartFrank GrosveldSjaak PhilipsenBart Lambrecht

A1 Journal Article in BLOOD

Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines

C ZANAZZIR HERSMUSIM VELTMANAJM GILLISE VAN DRUNENHB BEVERLOOJPJJ HEGMANSM VERWEIJBart LambrechtJW OOSTERHUISLHJ LOOIJENGA

A1 Journal Article in GENES CHROMOSOMES & CANCER

HIF1a expression in bronchial biopsies correlates with tumor microvascular saturation determined using optical spectroscopy

JGJV AertsA AmelinkC van der LeestJPJJ HegmansA HemmesB den HamerHCJM SterenborgHC HoogstedenBart Lambrecht

A1 Journal Article in LUNG CANCER

Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function

M IDZKOHamida HammadM VAN NIMWEGENM KOOLN VOSHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Keratinocyte growth factor induces expansion of murine peripheral CD4(+)Foxp3(+) regulatory T CON and increases their thymic output

M BRUINSMAPL VAN SOESTPJM LEENENBart LambrechtT CUPEDOB LOWENBERGJJ CORNELISSENE BRAAKMAN

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Lung dendritic cell migration

Hamida HammadBart Lambrecht

A1 Journal Article in ADVANCES IN IMMUNOLOGY, VOL 93

Lung dendritic cells : from basic physiology to clinical applications

A1 Journal Article in ACTA CLINICA BELGICA

Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets

G XANTHOUT ALISSAFIM SEMITEKOLOUDCM SIMOESE ECONOMIDOUM GAGABart LambrechtCM LLOYDV PANOUTSAKOPOULOU

A1 Journal Article in NATURE MEDICINE

Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection

Hermehin H. SmitsHamida HammadMenno van NimwegenThomas SoullieMonique WillartEllen LieversJonathan KadouchMirjam KoolJanneke Kos-van OosterhoudAndre M. DeelderBart LambrechtMaria Yazdanbakhsh

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proteomics of pleural effusion

Joost HegmansAnnabrita HemmesBart Lambrecht

Bookchapter in Proteomics of human body fluids : principles, methods, and applications

Respiratory syncytial virus differentially activates murine myeloid and plasmacytoid dendritic cells

I BOOGAARDM VAN OOSTENLS VAN RIJTF MUSKENSTG KIMMANBart LambrechtAM BUISMAN

A1 Journal Article in IMMUNOLOGY

The pressure mounts on lung dendritic cells

Bart LambrechtLM VAN DEN TOORN

Editorial material

2006

Alveolar macrophage in the driver's seat

Editorial material

An essential role for dendritic cells in human and experimental allergic rhinitis

A KLEINJANMonique WillartLS VAN RIJTGJ BRAUNSTAHLK LEMANS JUNGHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An unexpected role for the anaphylatoxin C5a receptor in allergic sensitization

Editorial material

Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4(+) T cell activation

H KUIPERSF MUSKENSMonique WillartD HIJDRAFBJ VAN ASSEMAAJ COYLEHC HOOGSTEDENBart Lambrecht

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic cells in asthma

Hamida HammadBart Lambrecht

Bookchapter in Handbook of dendritic cells : biology, diseases, and therapies

Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

M IDZKOHamida HammadM VAN NIMWEGENM KOOLT MULLERT SOULLIEMonique WillartD HIJDRAHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses

JPJJ HEGMANSA HEMMESHamida HammadL BOONHC HOOGSTEDENBart Lambrecht

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

Hamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rôle des différentes populations de cellules dendritiques dans l'asthme allergique

Hamida HammadBart Lambrecht

A1 Journal Article in REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE

2005

Dendritic cell subsets and immune regulation in the lung

HJ DE HEERHamida HammadMA KOOLBart Lambrecht

A1 Journal Article in SEMINARS IN IMMUNOLOGY

Dendritic cells and the regulation of the allergic immune response

A1 Journal Article in ALLERGY

Dendritic cells in asthma: a function beyond sensitization

LS VAN RIJTBart Lambrecht

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells

LPJJ HEGMANSA HEMMESJG AERTSHC HOOGSTEDENBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

In vivo depletion of lung CD11c(+) dendritic cells during allergen challenge abrogates the characteristic features of asthma

LS VAN RIJTS JUNGA KLEINJANN VOSMonique WillartC DUEZHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Modification of dendritic cell function as a tool to prevent and treat allergic asthma

H KUIPERSBart Lambrecht

A1 Journal Article in VACCINE

Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease

L VISSERHJ DE HEERLA BOVEND VAN RIELM VAN MEURSMJ MELIEFU ZAHRINGERJ VAN STRIJPBart LambrechtEE NIEUWENHUISJD LAMAN

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Respiratory viral infections and asthma pathogenesis: A critical role for dendritic cells?

LS VAN RIJTCHG VAN KESSELI BOOGAARDBart Lambrecht

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

Surfactant pretreatment ameliorates ischemia-reperfusion injury of the lung

NP VAN DER KAAIJJJ HAITSMAJ KLUINBart LambrechtB LACHMANNRWF DE BRUINAJJC BOGERS

A1 Journal Article in EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Treatment of experimental asthma by decoy-mediated local inhibition of activator protein-1

Christophe DesmetPhilippe GossetEmmanuelle HenryVirginie GarzéPedro FaiscaNanda VosFabrice JasparDorothée MélotteBart LambrechtDaniel DesmechtBernard PajakMuriel MoserPierre LekeuxFabrice Bureau

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2004

A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma

LS VAN RIJTH KUIPERSN VOSD HIJDRAHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice

H YUDAY ADACHIO TAGUCHIEC GABAZZAO HATAJIH FUJIMOTOS TAMAKIK NISHIKUBOK FUKUDOMECN D'ALESSANDRO-GABAZZAJ MARUYAMAM IZUMIZAKIM IWASEI HOMMAR INOUEH KAMADAT HAYASHIM KASPERBart LambrechtPJ BARNESK SUZUKI

A1 Journal Article in BLOOD

Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma

Hamida HammadHJ DE HEERT SOULLIEV ANGELIF TROTTEINHC HOOGSTEDENBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses

W ANGELID STAUMONTAS CHARBONNIERHamida HammadP GOSSETM PICHAVANTBart LambrechtM CAPROND DOMBROWICZF TROTTEIN

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Airways infection with virulent Mycobacterium tuberculosis delays the influx of dendritic cells and the expression of costimulatory molecules in mediastinal lymph nodes

GS GARCIA-ROMOA PEDROZA-GONZALEZD AGUILAR-LEONH OROZCO-ESTEVEZBart LambrechtI ESTRADA-GARCIAL FLORES-ROMOR HERNANDEZ-PANDO

A1 Journal Article in IMMUNOLOGY

Dendritic cells retrovirally overexpressing IL-12 induce strong Th1 responses to inhaled antigen in the lung but fail to revert established Th2 sensitization

H KUIPERSC HEIRMAND HIJDRAF MUSKENSMonique WillartS VAN MEIRVENNEK THIELEMANSHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Differential capacity of CD8 alpha(+) or CD8 alpha(-) dendritic cell subsets to prime for eosinophilic airway inflammation in the T-helper type 2-prone milieu of the lung

Hamida HammadVC DE VRIESR MALDONADO-LOPEZM MOSERC MALISZEWSKIHC HOOGSTEDENBart Lambrecht

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Essential role of dendritic cell CD80/86 costimulation in the induction, but not reactivation, of T(H)2 effector responses in a mouse model of asthma

LS VAN RIFTN VOSMonique WillartA KLEINJANAJ COYLEHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen

HJ DE HEERHamida HammadT SOULLIED HIJDRAN VOSMonique WillartHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

In situ analysis of lung antigen-presenting cells during murine pulmonary infection with virulent Mycobacterium tuberculosis

A PEDROZA-GONZALEZGS GARCIA-ROMOD AGUILAR-LEONJ CALDERON-AMADORR HURTADO-ORTIZH OROZCO-ESTEVEZBart LambrechtI ESTRADA-GARCIAR HERNANDEZ-PANDOL FLORES-ROMO

A1 Journal Article in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Proteomic analysis of exosomes isolated from human malignant pleural effusions

MP BARDJP HEGMANSA HEMMESTM LUIDERR WILLEMSENLAA SEVERIJNENJan Van MeerbeeckSA BURGERSHC HOOGSTEDENBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Proteomic analysis of exosomes secreted by human mesothelioma cells

JPJJ HEGMANSMPL BARDA HEMMESTM LUIDERMJ KLEIJMEERJB PRINSL ZITVOGELSA BURGERSHC HOOGSTEDENBart Lambrecht

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

The interplay of dendritic cells, Th2 cells and regulatory T cells in asthma

H KUIPERSBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

2003

Airway eosinophils accumulate in the mediastinal lymph nodes but lack antigen-presenting potential for naive T cells

LS VAN RIJTN VOSD HIJDRAVC DE VRIESHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Antigen-presenting cells

Henk C HoogstedenHamida HammadBart Lambrecht

Bookchapter in The immunological basis of asthma

B cell differentiation and IgE synthesis

Hamida HammadBart Lambrecht

Bookchapter in The immunological basis of asthma

Immunology of eosinophilic airway inflammation

Bart LambrechtLeonie S van RijtHarmjan Kuipers

Bookchapter in The immunological basis of asthma

Lipopolysaccharide-induced suppression of airway Th2 responses does not require IL-12 production by dendritic cells

H KUIPERSD HIJDRAVC DE VRIESHamida HammadJB PRINSAJ COYLEHC HOOGSTEDENBart Lambrecht

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Opinion - Taking our breath away: dendritic cells in the pathogenesis of asthma

Bart LambrechtHamida Hammad

Editorial material

Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: Consequences for the immune response

W ANGELIHamida HammadB STAELSM CAPRONBart LambrechtF TROTTEIN

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Prostaglandin D-2 inhibits airway dentritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1

Hamida HammadHJ DE HEERT SOULLIEHC HOOGSTEDENF TROTTEINBart Lambrecht

A1 Journal Article in JOURNAL OF IMMUNOLOGY

The immunological basis of asthma

The other cells in asthma: dendritic cell and epithelial cell crosstalk

Bart LambrechtHamida Hammad

A1 Journal Article in CURRENT OPINION IN PULMONARY MEDICINE

2002

Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31(hi)Ly6C(neg) bone marrow precursors in a mouse model of asthma

LS VAN RIJTJB PRINSPJM LEENENK THIELEMANSVC DE VRIESHC HOOGSTEDENBart Lambrecht

A1 Journal Article in BLOOD

Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells.

Pieter DepuydtBart LambrechtGuy JoosRomain Pauwels

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Monocyte-derived dendritic cells induce a house dust mite-specific Th2 allergic inflammation in the lung of humanized SCID mice: Involvement of CCR7

Hamida HammadBart LambrechtP POCHARDP GOSSETP MARQUILLIESAB TONNELJ PESTEL

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Myeloid dendritic cells make it to the top

Bart LambrechtHamida Hammad

Editorial material

2001

Dendritic cells as regulators od the immune response to inhaled allergen: Recent findings in animal models of asthma

Bart LambrechtC HOOGSTEDENRomain Pauwels

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo

MC NAWIJNGM DINGJANR FERREIRABart LambrechtA KARISF GROSVELDH SAVELKOULRW HENDRIKS

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Immunologists getting nervous: neuropeptides, dendritic cells and T cell activation

Editorial material

Lung dendritic cells and host immunity to infection

Bart LambrechtJB PRINSHC HOOGSTEDEN

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Role of dendritic cells and Th2 lymphocytes in asthma: Lessons from eosinophilic airway inflammation in the mouse

LS VAN RIJTBart Lambrecht

A1 Journal Article in MICROSCOPY RESEARCH AND TECHNIQUE

Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes.

Karim VermaelenInes Carro-MuinoBart LambrechtRomain Pauwels

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The dendritic cell in allergic airway diseases: a new player to the game

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

2000

Airway inflammation in asthma and chronic obstructive pulmonary disease with special emphasis on the antigen-presenting dendritic cell: influence of treatment with fluticasone propionate (vol 29, pg 116, 1999)

HC HoogstedenGT VerhoevenBart LambrechtJ-B Prins

Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model

Bart LambrechtRomain PauwelsB FAZEKAS DE ST GROTH

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation.

Bart LambrechtM DE VEERMANAJ COYLEJC GUTIERREZ-RAMOSK THEILEMANSRomain Pauwels

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Sensitization to inhaled antigen by intratracheal instillation of dendritic cells.

Bart LambrechtRenaat PelemanGillian BullockRomain Pauwels

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

1999

Airway inflammation in asthma and chronic obstructive pulmonary disease with special emphasis on the antigen-presenting dendritic cell: influence of treatment with fluticasone propionate

HC HoogstedenGT VerhoevenBart LambrechtJ-B Prins

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Allergen-induced changes in bone-marrow progenitor and airway dendritic cells in sensitized rats.

Bart LambrechtInes Carro-MuinoKarim VermaelenRomain Pauwels

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Antigen presenting dendrititic cells produce neurokinins to stimulate T cell proliferation.

Bart LambrechtEls EveraertPaul GermonpreInes Carro-MuinoM DE VEERMANK THIELEMANSS HUNT

Effect of ozone exposure on the pulmonary immune response induced by dendritic cells.

PO DEPUYDTBart LambrechtGuy JoosRomain Pauwels

Endogenously produced substance P contributes to lymphocyte proliferation induced by dendritic cells and direct TCR ligation

Bart LambrechtPaul GermonpreEls EveraertInes Carro-MuinoM DE VEERMANC DE FELIPESP HUNTK THIELEMANSGuy JoosRomain Pauwels

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Lung antigen presenting cells are an important source of substance P in allergic airway inflammation.

Els EveraertInes Carro-MuinoBart LambrechtGuy JoosRomain Pauwels

Presence of substance P and neurokinin 1 receptors in human sputum macrophages and U-937 cells.

Paul GermonpreGillian BullockBart LambrechtV VAN DE VELDEW LUYTENGuy JoosRomain Pauwels

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

1998

Cytokines and their receptors as therapeutic targets in asthma

Romain PauwelsGuy BrusselleKurt TournoyBart LambrechtJohan Kips

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice

Bart LambrechtB SALOMOND KLATZMANNRomain Pauwels

A1 Journal Article in JOURNAL OF IMMUNOLOGY

1997

The airway inflammatory response induced by intratracheal injection of antigen pulsed dendritic cells is modified by systemic adjuvant

Bart LambrechtRenaat PelemanGillian BullockRomain Pauwels

1996

Bronchiaal astma

Romain PauwelsBart Lambrecht

A4 Journal Article in BIJBLIJVEN (AMSTERDAM.)

The dendritic cell : its potent role in the respiratory immune response

Bart LambrechtRomain PauwelsGillian Bullock

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

1994

AGE-RELATED DIFFERENCES IN PRESENTATION, TREATMENT AND OUTCOME OF ACUTE MYOCARDIAL-INFARCTION.

Paul CalleLuc JordaensMarc De BuyzereL RUBBENSBart LambrechtDenis Clement

A1 Journal Article in CARDIOLOGY

1993

Signal averaged electrocardiography and echocardiography in athletes and age matched controls: importance of left ventricular hypertrophy.

Luc MissaultLuc JordaensBart LambrechtC DEMEESTERDaniel DuprezDenis Clement

A2 Journal Article in ACTA CARDIOLOGICA