Research Explorer

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Researcher

Amanda Gonçalves

Publications & Research Data

Awards & Distinctions

42 Results

2025

AI-driven histologic analysis of human Achilles tendinopathy provides a roadmap to unravel pathogenesis

Guillaume PlanckaertArne BurssensFlore StappersJulie CoudenysSofia DemolderIrem KayaMalaïka Van der LindenAmanda GonçalvesKelly LemeireBenjamin Pavie et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

BonAIr: an AI-driven histological validation of human Achilles tendinopathy provides a roadmap to unravel pathogenesis

Guillaume PlanckaertArne BurssensFlore StappersIrem KayaMalaïka Van der LindenAmanda GonçalvesBenjamin PavieAmber VanhaeckeJo Van DorpeJan Victor et al.

Unmasking budgerigar splenic leukocyte populations with single‐cell transcriptomics and multiplex RNA in situ hybridization

Anne De MeystKelly LemeireAmanda GonçalvesNiels VandammeDaisy Vanrompay

A1 Journal Article in JOURNAL OF IMMUNOLOGY RESEARCH

2024

Metabolite-based inter-kingdom communication controls intestinal tissue recovery following chemotherapeutic injury

Christopher AndersonLaura BoeckaertsPriscilla ChinJavier BurgoaWei XieAmanda GonçalvesGillian BlanckeSam BensonSebastian RogattiMariska S. Simpson et al.

A1 Journal Article in CELL HOST & MICROBE

Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair

Parul MehrotraSophia MaschalidiLaura BoeckaertsChristian MaueröderRochelle TixeiraJonathan PinneyJavier BurgoaVladimir SukhovYunus IncikChristopher Anderson et al.

A1 Journal Article in NATURE

TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice

Mario Ruiz PérezChristian MaueröderWolf SteelsBruno VerstraetenSahine LameireWei XieLaura WyckaertJelle HuysentruytTatyana DivertRia Roelandt et al.

A1 Journal Article in CELLULAR & MOLECULAR IMMUNOLOGY

Type 1 immunity enables neonatal thymic ILC1 production

Peter TougaardMario Ruiz PérezWolf SteelsJelle HuysentruytBruno VerstraetenJessica VettersTatyana DivertAmanda GonçalvesRia RoelandtNozomi Takahashi et al.

A1 Journal Article in SCIENCE ADVANCES

2023

Cell behavior changes and enzymatic biodegradation of hybrid electrospun poly(3-hydroxybutyrate)-based scaffolds with an enhanced piezoresponse after the addition of reduced graphene oxide

Roman ChernozemIgor PariyMaria A. A. SurmenevaVladimir V. V. ShvartsmanGuillaume PlanckaertJoost VerduijnStef GhyselsAnatolii AbalymovBogdan ParakhonskiyEric Gracey et al.

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

Phase separation-based visualization of protein-protein interactions and kinase activities in plants (vol 35, pg 3280, 2023)

Alaeddine SafiWouter SmaggheAmanda GonçalvesQing WangKe XuAna Fernandez SalinaBenjamin CappeFranck RiquetEvelien MylleDominique Eeckhout et al.

Phase separation-based visualization of protein-protein interactions and kinase activities in plants

Alaeddine SafiWouter SmaggheAmanda GonçalvesQing WangKe XuAna Fernandez SalinaBenjamin CappeFranck RiquetEvelien MylleDominique Eeckhout et al.

A1 Journal Article in PLANT CELL

2022

Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells

Anouk SmetJoão Portela CataniTine YsenbaertAmanda GonçalvesHarry KleanthousThorsten U. VogelXavier SaelensEmma Job

A1 Journal Article in PLOS ONE

Detection and quantification of protein aggregates in plants

Ujjal Jyoti PhukanSimon StaelensAmanda GonçalvesFrank Van BreusegemNúria S. Coll

Bookchapter in Plant proteostasis : methods and protocols

GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis

Dhruv ChauhanDieter DemonLieselotte Vande WalleOonagh PaerewijckAnnalisa ZecchinLeslie BosselerKarin SantoniRemi PlanesSilvia Ribó GenéAmelie Fossoul et al.

A1 Journal Article in EMBO REPORTS

Phase separation-based visualization of protein-protein interactions and kinase activities in plants

Alaeddine SafiWouter SmaggheAmanda GonçalvesKe XuAna Ibis FernandezBenjamin CappeFranck B. RiquetEvelien MylleDaniël Van DammeDanny Geelen et al.

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Martin GuilliamsJohnny BonnardelBirthe HaestBart VanderborghtCamille WagnerAnneleen RemmerieAnna BujkoLiesbet MartensTinne ThonéRobin Browaeys et al.

A1 Journal Article in CELL

2021

Microbes exploit death-induced nutrient release by gut epithelial cells

Christopher AndersonChristopher B. MedinaBrady J. BarronLaura KarvelyteTania Love AaesIrina LambertzJustin S. A. PerryParul MehrotraAmanda GonçalvesKelly Lemeire et al.

A1 Journal Article in NATURE

2020

An interactive ImageJ plugin for semi-automated image denoising in electron microscopy

Joris RoelsFrank VernaillenAnna KremerAmanda GonçalvesJan AeltermanHiep LuongBart GoossensWilfried PhilipsSaskia LippensYvan Saeys

A1 Journal Article in NATURE COMMUNICATIONS

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Lise Van WyngeneTineke VanderhaeghenSteven TimmermansJolien VandewalleKelly Van LooverenJolien SouffriauCharlotte WallaeysMelanie EggermontSam ErnstEvelien Van Hamme et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients

Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeKarsten SchmidtEline NysLaurens WeynantsJoachim WeisGert Van PeerJo Vandesompele et al.

Bookchapter in Myokines, adipokines, cytokines in muscle pathophysiology

2019

Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock

Tinneke DelvaeyeMaarten De SmetStijn VerwaerdeElke DecrockAleksandra CzekajRoosmarijn VandenbrouckeKelly LemeireAmanda GonçalvesWim DeclercqPeter Vandenabeele et al.

A1 Journal Article in SCIENTIFIC REPORTS

Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Tim HanderÁlvaro Daniel Fernández FernándezRobert KumpfPatrick WillemsHendrik SchatowitzDebbie RombautAn StaesJonah NolfRobin PottiePanfeng Yao et al.

A1 Journal Article in SCIENCE

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

Nathalia Moraes de VasconcelosGwendolyn VliegenAmanda GonçalvesEmilie De HertRosa Martín-PérezNina Van OpdenboschAnvesh JallapallyRuth Geiss-FriedlanderAnne-Marie LambeirKoen Augustyns et al.

A2 Journal Article in LIFE SCIENCE ALLIANCE

Effect of methylprednisolone on NFAT5 in Duchenne muscular dystrophy fibroblasts

Sandrine HerbeletAmanda GonçalvesJo VandesompeleJan De Bleecker

Epithelial HMGB1 delays skin wound healing and drives tumor initiation by priming neutrophils for NET formation

Esther HosteChristian MaueröderLisette Van HoveLeen CatrysseHanna-Kaisa VikkulaMozes SzeBastiaan MaesDyah KarjosukarsoLiesbet MartensAmanda Gonçalves et al.

A1 Journal Article in CELL REPORTS

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Emma PerssonKenneth VerstraeteInes HeyndrickxElien GevaertHelena Catharine AegerterJean-Michel PercierKim DeswarteKoen VerschuerenAnn DansercoerDelphine Gras et al.

A1 Journal Article in SCIENCE

Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

Evangelia BolliMatthias D'HuyvetterAleksandar MurgaskiDanielle BerusGeert StangeEmile J ClappaertSana ArnoukAna Rita Pombo AntunesAhmet KrasniqiTony Lahoutte et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

Antonella FioravantiFilip Van HauwermeirenSander E Van der VerrenWim JonckheereAmanda GonçalvesEls PardonJan SteyaertHenri De GreveMohamed LamkanfiHan Remaut

A1 Journal Article in NATURE MICROBIOLOGY

The proliferation of Duchenne muscular dystrophy fibroblasts cultured under inflammatory conditions is reduced by methylprednisolone through modulation of NFAT5 localization in the cell

Sandrine HerbeletAmanda GonçalvesJo VandesompeleJan De Bleecker

2018

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Sofie VoetConor Mc GuireNora HagemeyerArne MartensAnna SchroederPeter WieghoferCarmen DaemsOri StaszewskiLieselotte Vande WalleMarta Joana Costa Jordao et al.

A1 Journal Article in NATURE COMMUNICATIONS

Ancient origin of the CARD-coiled coil/Bcl10/MALT1-like paracaspase signaling complex indicates unknown critical functions

Jens StaalYasmine DriegeMira HaegmanAlice BorghiPaco HulpiauLaurens LievensIsmail Sahin GülSrividhya Sundararaman IyerAmanda GonçalvesIneke Dhondt et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients

Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeKarsten SchmidtEline NysLaurens WeynantsJoachim WeisGert Van PeerJo Vandesompele et al.

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99mTc-duramycin during TNF-induced SIRS

Tinneke DelvaeyeLeonie wyffelsSteven DeleyeKelly LemeireAmanda GonçalvesElke DecrockSteven StaelensLuc LeybaertPeter VandenabeeleDmitri Krysko

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D

Andrea Renate TeufelbergerMaria NordengrünHarald BraunTania MaesKatrien De GroveGabriële HoltappelsClara O'BrienSharen ProvoostHamida HammadAmanda Gonçalves et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2017

Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4

Nina Van OpdenboschHanne Van GorpMaarten VerdoncktPedro Henrique Viana SaavedraNathalia Moraes de VasconcelosAmanda GonçalvesLieselotte Vande WalleDieter DemonMagdalena MatusiakFilip Van Hauwermeiren et al.

A1 Journal Article in CELL REPORTS

Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus

Lei DengKenny RooseEmma JobRiet De RyckeEvelien Van HammeAmanda GonçalvesEef ParthoensLaetitia CiccheleroNiek SandersWalter Fiers et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2016

Monitoring ubiquitin-coated bacteria via confocal microscopy

Marie LorkMieke DelvaeyeAmanda GonçalvesEvelien Van HammeRudi Beyaert

Bookchapter in Proteostasis

NFAT5 in Duchenne muscular dystrophy cultured myoblasts after exposure to hyperosmolar salt conditions

Sandrine HerbeletAmanda GonçalvesElly De VlieghereGert Van PeerBoel De PaepeChris GuerinJo VandesompeleOlivier De WeverJan De Bleecker

NFAT5 in inflammatory myopathies and Duchenne muscular dystrophy

Sandrine HerbeletAmanda GonçalvesElly De VlieghereBoel De PaepeChris GuerinOlivier De WeverJan De Bleecker

The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors

Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeChris GuerinOlivier De WeverJan De Bleecker

2014

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten RemijsenVera GoossensSasker GrootjansC Van den HauteNele VanlangenakkerYves DondelingerRia RoelandtInge BruggemanAmanda GonçalvesMathieu Bertrand et al.

A1 Journal Article in CELL DEATH & DISEASE

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates

Yves DondelingerWim DeclercqSylvie MontessuitRia RoelandtAmanda GonçalvesInge BruggemanPaco HulpiauKathrin WeberClark A SehonRobert W Marquis et al.

A1 Journal Article in CELL REPORTS

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

Nozomi TakahashiLars VereeckeMathieu BertrandLinde DuprezScott B BergerTatyana DivertAmanda GonçalvesMozes SzeBarbara GilbertStephanie Kourula et al.

A1 Journal Article in NATURE