Research Explorer

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Onderzoeker

Abhishek Iyer

Prijzen & Erkenningen

16 Resultaten

2023

Development of teixobactin analogues containing hydrophobic, non-proteogenic amino acids that are highly potent against multidrug-resistant bacteria and biofilms

Anish ParmarRajamani LakshminarayananAbhishek IyerEunice Tze Leng GohTsz Ying ToJoey Kuok Hoong YamLiang YangEnas NewireMaria C. RobertsonStephen H. Prior et al.

A1 Artikel in een tijdschrift in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2021

5-Hydroxy-pyrrolone based building blocks as maleimide alternatives for protein bioconjugation and single-site multi-functionalization

Ewout De GeyterEirini AntonatouDimitris KalaitzakisSabina SmolenAbhishek IyerLaure TackEmiel OngenaeGeorgios VassilikogiannakisAnnemieke Madder

A1 Artikel in een tijdschrift in CHEMICAL SCIENCE

2019

Teixobactins : a new class of 21st century antibiotics to combat multidrug-resistant bacterial pathogens

Abhishek IyerAnnemieke MadderIshwar Singh

Redactioneel materiaal

2018

Cysteines and disulfide-bridged macrocyclic mimics of teixobactin analogues and their antibacterial activity evaluation against methicillin-resistant Staphylococcus aureus (MRSA)

Ruba MalkawiAbhishek IyerAnish ParmarDaniel G. LloydEunice Tze Leng GohEdward J. TaylorSarir SarmadAnnemieke MadderRajamani LakshminarayananIshwar Singh

A1 Artikel in een tijdschrift in PHARMACEUTICS

Design and syntheses of highly potent teixobactin analogues against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) in vitro and in vivo

Anish ParmarRajamani LakshminarayananAbhishek IyerVenkatesh MayandiEunice Tze Leng GohDaniel G LloydMadhavi Latha S ChalasaniNavin Kumar VermaStephen H PriorRoger W Beuerman et al.

A1 Artikel in een tijdschrift in JOURNAL OF MEDICINAL CHEMISTRY

Reviving old protecting group chemistry for site-selective peptide-protein conjugation

Smita GunnooAbhishek IyerWillem VanneckeKlaas DecoeneTim HebbrechtJan GettemansMathias LagaStefan LoverixIgnace LastersAnnemieke Madder

A1 Artikel in een tijdschrift in CHEMICAL COMMUNICATIONS

2017

Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities

Anish ParmarStephen H PriorAbhishek IyerCharlotte S VincentDorien Van LysebettenEefjan BreukinkAnnemieke MadderEdward J TaylorIshwar Singh

A1 Artikel in een tijdschrift in CHEMICAL COMMUNICATIONS

Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres

Anish ParmarAbhishek IyerDaniel G LloydCharlotte S VincentStephen H PriorAnnemieke MadderEdward J TaylorIshwar Singh

A1 Artikel in een tijdschrift in CHEMICAL COMMUNICATIONS

Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding

Anish ParmarAbhishek IyerStephen H PriorDaniel G LloydEunice Tze Leng GohCharlotte S VincentTimea Palmai-PallagCsanad Z BachratiEefjan BreukinkAnnemieke Madder et al.

A1 Artikel in een tijdschrift in CHEMICAL SCIENCE

2016

DNA recognition and antimicrobial compounds : exploring the versatility of peptides

Abhishek IyerAnnemieke MadderIshwar Singh

Efficient total syntheses and biological activities of two teixobactin analogues

Anish ParmarAbhishek IyerCharlotte S VincentDorien Van LysebettenStephen H PriorAnnemieke MadderEdward J TaylorIshwar Singh

A1 Artikel in een tijdschrift in CHEMICAL COMMUNICATIONS

2015

Cyclodextrin-peptide conjugates for sequence specific DNA binding

Yara Ruiz GarciaJan ZelenkaY Vladimir PabonAbhishek IyerMiloš BuděšínskýTomáš KrausCI Edvard SmithAnnemieke Madder

A1 Artikel in een tijdschrift in ORGANIC & BIOMOLECULAR CHEMISTRY

Sequence-selective DNA recognition and enhanced cellular up-take by peptide–steroid conjugates

Yara Ruiz GarciaAbhishek IyerDorien Van LysebettenY Vladimir PabonBenoit LouageMalgorzata HoncharenkoBruno De GeestCI Edvard SmithRoger StrömbergAnnemieke Madder

A1 Artikel in een tijdschrift in CHEMICAL COMMUNICATIONS

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake

Abhishek IyerDorien Van LysebettenYara Ruiz GarciaBenoit LouageBruno De GeestAnnemieke Madder

A1 Artikel in een tijdschrift in ORGANIC & BIOMOLECULAR CHEMISTRY

2014

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies

Melanie SandersYirong GuoAbhishek IyerYara Ruiz GarciaAnastasia GalvitaArne HeyerickDieter DeforceMartijn RisseeuwSerge Van CalenberghMarc Bracke et al.

A1 Artikel in een tijdschrift in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

alpha-Helix stabilization of the basic region of the monomeric transcription factor GCN4 using stapled peptides for DNA binding

Abhishek IyerYara Ruiz GarciaAnnemieke Madder