Project

Generation of a human interactome network using MAPPIT

Code
31512607
Duration
01 January 2007 → 31 December 2009
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Medical biochemistry and metabolism
    • Endocrinology and metabolic diseases
    • Medical biochemistry and metabolism
    • Endocrinology and metabolic diseases
    • Medical biochemistry and metabolism
Keywords
MAPPIT protein function interactome
 
Project description

Protein-protein interactions are crucial for virtually all biological processes. Detailed interaction networks can provide novel insights in the normal and pathological functions of a given protein. Analysis of the human interactome is done using the yeast two-hybrid technique, whereby the accuracy is sometimes questioned. We will contribute to these large-scales programs by asystematic analysis of observed interactions using MAPPIT.