Research Explorer

Project

The role of aortic side branches in the initiation and evolution of ascending aortic aneurysm and dissecting abdominal aortic aneurysm in ApoE -/- mice
Code
3E022415
Duration
01 October 2015 → 30 September 2019
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Engineering and technology
    • Biofluid mechanics
    • Rehabilitation engineering
    • System and whole body biomechanics
    • Tissue and organ biomechanics
Keywords
mouse model pcxtm imaging aneurysm
 
Project description

The goal of this project is to investigate the pathology of aortic aneurysms in the ApoE-/- mouse model. Using super-resolution synchrotron images and image-guided histology we will study the role of small side branches in the initation and evolution of dissecting abdominal aortic aneurysm. We will also visualize the initation and evolution of ascending aneurysms in the same mouse model.