Project

Paracrine effects during group culture of bovine embryos as a model for human embryo culture

Code

3G021009

Duration

01 January 2009 → 31 December 2014

Funding

Research Foundation - Flanders (FWO)

Promotor

Ann Van Soom

Research disciplines

Natural sciences
- Animal biology
- Genetics
Medical and health sciences
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Nursing
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural and food sciences

Keywords

bovine human group culture embryo paracrine

Project description

Bovine embryos are routinely produced in goups of 25 because of the improved embryo development in such setting. The superiority of the system is probably caused by the secretion of embryonic paracrine factors, which are positively influencing neighbouring embryos. In part 1 we will investage differential secretion between good (fast) and bad (slow) embryos. Next this model will be used in a human preclinical and clinical study.