Research Explorer

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Project

Study of RIPK1 involvement and regulation in inflammatory and infectious diseases

Outputs and Outcomes

Publications

RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia

Onay VeliOyku KayaAna Beatriz VarandaXimena HildebrandtPeng XiaoYann EstornesMatea PoggenbergYuan WangManolis PasparakisMathieu BertrandHenning WalczakAlessandro AnnibaldiAlessandra K. CardozoNieves Peltzer et al.

A1 Journal Article in MOLECULAR METABOLISM

Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma

Jelle VerhoevenKathryn A. JacobsFrancesca RizzolloFrancesca LodiYichao HuaJoanna PoźniakAdhithya Narayanan SrinivasanDiede HoubaertGautam ShankarSanket MoreMarco B. SchaafNikolina Dubroja LakicMaarten GanneJochen LamoteJohan Van WeyenberghLouis BoonOliver BechterFrancesca BosisioYasuo UchiyamaMathieu BertrandJean Christophe MarineDiether LambrechtsGabriele BergersMadhur AgrawalPatrizia Agostinis et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Yves DondelingerDario PriemJon HuygheTom DelanghePeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

Beyond ferrostatin-1 : a comprehensive review of ferroptosis inhibitors

Camilla ScarpelliniGreta KlejborowskaCaroline LanthierBehrouz HassanniaTom Vanden BergheKoen Augustyns

A1 Journal Article in TRENDS IN PHARMACOLOGICAL SCIENCES

Cell death checkpoints in the TNF pathway

Jon HuygheDario PriemMathieu Bertrand

A1 Journal Article in TRENDS IN IMMUNOLOGY

Inhibition of RIPK1 kinase does not affect diabetes development : beta-cells survive RIPK1 activation

Tatiana TakiishiPeng XiaoMarie FranchimontEduardo H. GilglioniErick N. ArrobaEsteban N. GurzovMathieu BertrandAlessandra K. Cardozo

A1 Journal Article in MOLECULAR METABOLISM

From PERK to RIPK1 : design, synthesis and evaluation of novel potent and selective necroptosis inhibitors

Camilla ScarpelliniSophie ValemboisKenneth GoossensMike VadiCaroline LanthierGreta KlejborowskaPieter Van der VekenHans De WinterMathieu BertrandKoen Augustyns

A1 Journal Article in FRONTIERS IN CHEMISTRY

LC3-independent autophagy is vital to prevent TNF cytotoxicity

Dario PriemJon HuygheMathieu Bertrand

A1 Journal Article in AUTOPHAGY

Death by TNF : a road to inflammation

Geert van LooMathieu Bertrand

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.

Jon HuygheDario PriemLisette Van HoveBarbara GilbertJ FritschY UchiyamaEsther HosteGeert van LooMathieu Bertrand

A1 Journal Article in SCIENCE

Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells

Sam BlanchettYves DondelingerAlessandro BarbaruloMathieu BertrandBenedict Seddon

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

Marine GrosElodie SeguraDerek C. RookhuizenBlandine BaudonSandrine Heurtebise-ChretienNina BurgdorfMathieu MaurinEugene A. KappRichard J. SimpsonPatrycja KozikJose A. VilladangosMathieu BertrandMarianne BurbageSebastian Amigorena et al.

A1 Journal Article in CELL REPORTS