A high-throughput electroporation system for rapid strain development for industrial biotechnology purposes

15 December 2022 → 14 December 2024
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Synthetic biology
  • Engineering and technology
    • Sustainable development
    • Bioprocessing, bioproduction and bioproducts
    • Industrial microbiology
    • Industrial biotechnology not elsewhere classified
Industrial biotechnology Synthetic biology Transformation High-throughput equipment Metabolic engineering
Project description

Electroporation is a key transformation method allowing high-efficiency transformation of a wide range of microbial strains. Here, we want to replace our end-of-life electroporation device allowing only one simultaneous electroporation by one allowing high-throughput transformation of no less than 96 strains at once. This system will allow us to rapidly transform both model and non-model organisms with highly interesting properties for industrial biotechnology purposes. Doing so, we can create production strains with economically viable production titres that will enable the shift towards a biobased economy.