Research Explorer

Project

Study of the importance of the choroid plexus (CP) in natural aging with focus on interferon (IFN) signalling
Code
3F012216
Duration
01 October 2016 → 12 January 2021
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Systems biology
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Hematology
    • Laboratory medicine
    • Neurosciences
    • Hematology
    • Laboratory medicine
    • Neurosciences
    • Hematology
    • Laboratory medicine
    • Neurosciences
Keywords
blood-brain barrier blood-CSF barrier inflammaging
 
Project description

The choroid plexus (CP) plays an important role in the central nervous system. Several morphological changes occur in the CP during aging, accompanied by an increase in interferon (IFN) dependent gene expression. Here, I want to gain more insight into the role of IFNs in aging, what causes IFN induction and evaluate the effects of IFN inhibition.