Research Explorer

Project

Efficacy and immunological aspects of self-amplifying (sa) RNA vaccines encoding avian influenza antigens
Code
01CD01124
Duration
15 June 2024 → 14 January 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Agricultural and food sciences
    • Veterinary genetics
    • Other veterinary sciences not elsewhere classified
Keywords
vaccination Self-amplifying RNA platform avian influenza
 
Project description
The first part of the PhD thesis focuses on the design and in vivo evaluation of 4 saRNA vaccines encoding different forms of the HA-antigen of the H5N1 avian influenza virus. The second part aims to determine whether immune responses are elicited against the viral replicase complex and whether this affects the performance of the saRNA vaccine platform.