Project

Functional in-vitro ligand binding and in-vivo imaging of the opioid- and serotonine-receptorsystem in function of pain management in dogs

Code
01J06109
Duration
01 January 2009 → 30 June 2014
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Anaesthesiology
    • Intensive care and emergency medicine
    • Neurosciences
    • Anaesthesiology
    • Intensive care and emergency medicine
    • Neurosciences
    • Anaesthesiology
    • Intensive care and emergency medicine
    • Neurosciences
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural and food sciences
Keywords
SPET opioidreceptor dogs functional imaging opioidradioligand serotonine-A2-receptor analgesia
 
Project description

Study about opioidligand-binding on opioid-receptors (u) in the central nervous system to evaluate the specific distribution and density of the u-receptors in dogs. Therefore, a specific opioidradioligand will be developed, followed by imaging of opioid- and serotonine-receptorbinding by SPET. Finally the influence of the administration way on binding will be examined.