Research Explorer

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Project

The role of myosin II in cancer invastion

Outputs and Outcomes

Code

3G018107

Duration

01 January 2007 → 31 December 2009

Funding

Research Foundation - Flanders (FWO)

Promotor

Marc Bracke

Research disciplines

Medical and health sciences
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology

Keywords

cadherin invasion myosin

Project description

Myosin II was detected in invasive breast cancer cellines but not in not-invasive ones. The causal relationship between pyosin II and invasion is investigated and the actionmechanism, which presumably implicaties cadherins and integrins, is studied. Furthermore the effect of anti-invasive agents on myosin II, and the expression of the molecule in surgically removed breast cancer specimens fall within the project.

English

Dutch

English

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