Project

Characterization of the role of MALT1 paracaspase in antiviral immunity

Duration
01 January 2012 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
    • Microbiology
    • Immunology
    • Medical biochemistry and metabolism
Keywords
infection immunity signal tranduction virus
 
Project description

MALT1 is an intracellular protease that has so far mainly been studied in the context of antigen induced signaling in lymphocytes. In this project we aim to study the role of MALT1 in innate immunity against viral infection. We will concentrate on the role of MALT1 in antiviral signaling in response to specific pathogen recognition receptors.