Research Explorer

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Project

Characterizing and targeting aberrant splicing activity in acute leukemia

Outputs & Impact

Publications & research data ( 10 )

Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia

Patrícia AmaralRhona ChristieDaisy O. F. GreshamEmma J. M. LucasLuyao Kevin XuLena BehrmannJonathan BondSofie DegermanFrederik W. van DelftSteven Goossens et al.

A1 Journal Article in LEUKEMIA

Depletion of the RNA binding protein QKI and circular RNA dysregulation in T-cell acute lymphoblastic leukemia

Alessia BuratinBruno PalhaisEnrico GaffoJuliette RoelsJulie MorscioJolien Van LaereSilvia OrsiGeertruij Te KronniePieter Van VlierberghePanagiotis Ntziachristos et al.

A1 Journal Article in HAEMATOLOGICA

HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia

Jonas De KeselIgor FijalkowskiTim PietersCristina BorinKasper Thorhauge ChristensenManou WittouckJolien Van LaereLaura GuerreroLindy ReunesMarino Caruso et al.

A1 Journal Article in BLOOD

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia

Lisa DemoenFilip MatthijssensLindy ReunesBruno PalhaisBéatrice LintermansSara T'SasIgor FijalkowskiJoachim TaminauMuluembet Z. AkeleSiska Van Belle et al.

A1 Journal Article in SCIENCE ADVANCES

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De AlmeidaSara T'SasLuca PagliaroIgor FijalkowskiWouter SleeckxHannah Van SteenbergeRaffaella ZamponiBéatrice LintermansWouter Van LoockeBruno Palhais et al.

A1 Journal Article in HEMASPHERE

A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia

Igor FijalkowskiJin WangQi JinJolien Van LaereValentina SerafinJohn D. CrispinoPanagiotis Ntziachristos

A1 Journal Article in LEUKEMIA

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette Roels et al.

A1 Journal Article in HAEMATOLOGICA

Emerging epigenetic and posttranslational mechanisms controlling resistance to glucocorticoids in acute lymphoblastic leukemia

Cristina BorinTim PietersValentina SerafinPanagiotis Ntziachristos

A1 Journal Article in HEMASPHERE

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi JinBlanca Gutierrez DiazTim PietersYalu ZhouSonali NarangIgor FijalkowskiCristina BorinJolien Van LaereMonique PaytonByoung-Kyu Cho et al.

A1 Journal Article in SCIENCE ADVANCES

Splicing dysregulation in human hematologic malignancies : beyond splicing mutations

Jonas De KeselIgor FijalkowskiJustin TaylorPanagiotis Ntziachristos

A1 Journal Article in TRENDS IN IMMUNOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )