Research Explorer

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Project

Characterizing and targeting aberrant splicing activity in acute leukemia

Outputs and Outcomes

Publications

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia

Lisa DemoenFilip MatthijssensLindy ReunesBruno PalhaisBéatrice LintermansSara T'SasIgor FijalkowskiJoachim TaminauMuluembet Z. AkeleSiska Van BelleTom TaghonDieter DeforceFilip Van NieuwerburghGeert BerxPanagiotis NtziachristosZeger DebyserKaat DurinckTim PietersSteven GoossensPieter Van Vlierberghe et al.

A1 Journal Article in SCIENCE ADVANCES

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De AlmeidaSara T'SasLuca PagliaroIgor FijalkowskiWouter SleeckxHannah Van SteenbergeRaffaella ZamponiBéatrice LintermansWouter Van LoockeBruno PalhaisAlexandra ReekmansValentina BardelliLisa DemoenLindy ReunesDieter DeforceFilip Van NieuwerburghAlex KentsisPanagiotis NtziachristosNadine Van RoyBarbara De MoerlooseCristina MecucciRoberta La StarzaGiovanni RotiSteven GoossensPieter Van VlierbergheTim Pieters et al.

A1 Journal Article in HEMASPHERE

A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia

Igor FijalkowskiJin WangQi JinJolien Van LaereValentina SerafinJohn D. CrispinoPanagiotis Ntziachristos

A1 Journal Article in LEUKEMIA

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette RoelsMalaïka Van der LindenJo Van DorpePanagiotis NtziachristosFrederik W. Van DelftMarc R. MansourTim PietersTim LammensBarbara De MoerlooseCharles E. De BockSteven GoossensPieter Van Vlierberghe et al.

A1 Journal Article in HAEMATOLOGICA

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi JinBlanca Gutierrez DiazTim PietersYalu ZhouSonali NarangIgor FijalkowskiCristina BorinJolien Van LaereMonique PaytonByoung-Kyu ChoCuijuan HanLimin SunValentina SerafinGeorge YacuWouter Von LoockeGiuseppe BassoGiulia VeltriIngrid DrevenyIssam Ben-SahraYoung Ah GooStephanie L. SafgrenYi-Chien TsaiBeat BornhauserPraveen Kumar SuraneniAlexandre Gaspar-MaiaIrawati KandelaPieter Van VlierbergheJohn D. CrispinoAristotelis TsirigosPanagiotis Ntziachristos et al.

A1 Journal Article in SCIENCE ADVANCES

Splicing dysregulation in human hematologic malignancies : beyond splicing mutations

Jonas De KeselIgor FijalkowskiJustin TaylorPanagiotis Ntziachristos

A1 Journal Article in TRENDS IN IMMUNOLOGY