Code
3F003112
Duration
01 October 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Animal biology
- Genetics
-
Agricultural and food sciences
- Veterinary medicine
Keywords
runx
teeth
fgf
zebrafish
Project description
In this project, we wish to test the hypothesis that the transcription factor runx functions in an fgf signaling loop to regulate the formation of replacement teeth in zebrafish. We will test this hypothesis by (1) manipulating fgf signaling and studying its effects on runx expression and associated phenotype, and (2) manipulating runx expression itself through gain- and loss-of-function approaches.