Project

Exploration of macrophage-specific molecules for cell-directed therapy

Duration
01 October 2010 → 01 October 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
  • Engineering and technology
    • Biomaterials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
Keywords
cell-directed therapy macrophages immunoconjugates toxin antigen
 
Project description

Apart from their essential and vital homeostatic role, macrophages are also involved in many pathological conditions and they can function as a hiding place for intracellular pathogens. The use of macrophage-restricted molecules as a gateway for therapeutic immunoconjugates will be evaluated as a strategy to combat severl diseases