Project

Genetic analysis of cytokines and growth factors involved in the development of radiotherapy complications

Code
3E006109
Duration
01 October 2009 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Laboratory medicine
    • Medical systems biology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
Keywords
prediction cytokines growth factors radiotherapy complications polymorphisms
 
Project description

the association between genetic variations in cytokines and growth factors and the development of specific normal tissue radiation toxicity will be investigated. This has to lead to the construction of prognostic models which can predict radiation toxicity on the basis of individual genetic profiles. Risk prediction using these models will enable to individualize treatment schedules and to reduce normal tissue radiation toxicity.