Development and validation of a biomarker to predict severe acute and late dysphagia and therapy response in head and neck cancer patients treated with radio(chemo)therapy

01 July 2009 → 30 September 2012
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
dysphagia biomarker individual risk prediction modeling
Project description

Severe acute and chronic dysphagia, SAD and SCD, respectively, are side effects of radio(chemo)therapy for head-and-neck cancer. The project aims at refining and validating of the SAD biomarker, developing a SCD biomarker and their testing in preventive therapeutic intervention. Both biomarkers are constructed by multivariate logistic regression using predictor-variables reflecting the injury-causing treatment and the susceptibility of the individual patient.